Click here to switch to the map view.

The map label for this gene is mdtO [H]

Identifier: 73538182

GI number: 73538182

Start: 1011272

End: 1013269

Strand: Direct

Name: mdtO [H]

Synonym: Reut_B4353

Alternate gene names: 73538182

Gene position: 1011272-1013269 (Clockwise)

Preceding gene: 73538181

Following gene: 73538183

Centisome position: 37.1

GC content: 65.67

Gene sequence:

>1998_bases
ATGGCGCAGCCTGCCGCTGACAAGCTGCGCCTGCGCCTTGCCGATATCGGTGCACTGCTCGCGCCGTTGCCAGGCCGCTA
TGCGGGCGCGACCCGTATCACCGTTGGCTGCACGCTGACGGTATTGGTCACAAGTATCTACGGCACGCCAGAGGCGGCCA
TCTCGGCATACGTCATCTTCTTCATCAACCGCGCCGACCGGACCACCAGCATCATCATGAGCGCGGCAGCACTGGTGCTG
GTCAGCCTGATCATTGCGCTGGTGGTGTGGCTCGCCGACTTCAGCGTCGATGACCCCATGCGCCGCGTAACGTGCATGGC
GGTGCTGTCTGCTGTCCTGCTCTTCCTGACTTCGGCCAGCAAGCTGCGGCCGGTGGGCGCGATCGTCGCGATGATCATCG
GCTTCGCACTCGACGAACTCGGGCTCGTGCCCGGTGGCGAAGTCGCGACGCGCGCACTGCTCTATGCCTGGCTGATGGTG
GCGATCCCGATCGGCGTGAACATTGTCGTCAACCTCGCGATGGGTCCGTCGCCGCGCCGGCTGGCAACGGACCGCCTTGC
GCATTGCCTGCGTATAGCCGCGCGATGCCTGCGGGACCCGCTGGACAACGGCGGCGGGGACGCATTGCATGAGGCGCTGC
ATGGCGGCCTTCAACCCGTCGCGGGCTGGCTCAGGCTTGCCAGGGTCGAAGGCGCCCTCAACGTCCAGGATCTGCACGCG
CTGCAGCAGGCAACGGCATCGACCCTTGCCATCCTGCTAGCCGCCGACGTGATGCAACGACAATCCAGCGCACAGCTTCC
ATCGGCCACGGCAGCAAGCCTTGCAGACACGCTCGACGAAATGGCCCGCATGCTCGCTGCTGGCGGCTATCCGCTCGAGA
TTGCATTGCAGGCAGCGCCCATCGACAACCTCTCGCCGGTTCAACAAGCCGTCTTGCGCGAGCTGGTCGCGGCCATCGAT
GGCTATGCCGAAGCCGGCACAGATCCCAGCGATGCGCCGGCACGCGCAGCGGCAACGCCGAAAAGCGGTTTTCTGAGCGC
CGACGCATTCACCAATCCCGACCACGTCCGCTACGCGCTCAAGACCACCGGCGCGGCGATGTTCTGCTACGTGCTGTACC
AGCAGCTCAACTGGCCCGGCATTCATACCTGCTTCATCACCTGCTATCTGGTGTCGCTCGGCACCACGGCCGAGTCCGTG
GAAAAGCTCTGGCTGCGTTTGGCCGGATGCCTGGTCGGCGCGGTGATCGGGACTGCCGCCATCGTCTACGTGGTCCCGTC
GCTGTCGTCCATCGGCGGCCTGATGCTGCTGGTGTTTGCCGGCACGTGGATTTCCGCATGGGTGGCACAGGGCTCGCCGC
GCATTGCGTATGCGGGCTTCCAGATTGCGTTTGCGTTCTACCTGTGCGTGGTGCAGGGCGCCGCGCCCGGCTTCGACCTG
ACTATCGCACGTGACCGCGTGATCGGCGTATTGCTTGGCAACTTGGTCGTCTACCTGGTGTTCACGCGTATCTGGCCAGT
CAGCATCGCCGGGCGCATCGAATCCGCGCTGGCGGCACTGGTCACGCAATGGCAGGCGCTGGTCGATACGCCGCAGCCCA
CCGCGCGGCGCCAGCATGCGGCAGCCGCGCTCGCCCTGCATGGCACGATCACGCAGGACCTGATTCTGGCGCACTACGAA
CCGGCTTCCGTCGGGCCCGCACAGGAATGGGTGGACATCCACCGCGAGCGGCTGGCCACCCTCGATGCGATCTCCGGTCC
CATGTTCCTGCTCGCCGAGCGCTTTCCCGGTGATCCGGCGCTTGCACAGCGCCTGCACCGTCTGCGGACCGACATCCCGC
TGCAGACAGCCCCGCAGCACGCTGAAGCGATACCCGATGCTCCCGACGATGTCCGGGCCCGCCAGGCACTGCTCGCCATC
GTCGACCAACAACTCGAAACGTCCCATGCCGACGCGTCGGACACGGGCTCCCCTTCATCGATTCATGCGCAAACCTGA

Upstream 100 bases:

>100_bases
TGGGTGCGCGTGGCCAAGCGCTTCCCGGTGCGAATCCGCCTGGAAGACCCGCCCGAGGCACTGGCCCGCGTGGGCGCGAG
CGCAACTGTCGAGATCCGGC

Downstream 100 bases:

>100_bases
GTCCCTGGCCGCGCTGACGCTGTGCGCGCTGACCCTGGCGGGCTGCGCCACGTCGTCGCTCGACCTCGCGCCGGAGCAGC
CGGACCGCCCGTGGCATCCC

Product: fusaric acid resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 665; Mature: 664

Protein sequence:

>665_residues
MAQPAADKLRLRLADIGALLAPLPGRYAGATRITVGCTLTVLVTSIYGTPEAAISAYVIFFINRADRTTSIIMSAAALVL
VSLIIALVVWLADFSVDDPMRRVTCMAVLSAVLLFLTSASKLRPVGAIVAMIIGFALDELGLVPGGEVATRALLYAWLMV
AIPIGVNIVVNLAMGPSPRRLATDRLAHCLRIAARCLRDPLDNGGGDALHEALHGGLQPVAGWLRLARVEGALNVQDLHA
LQQATASTLAILLAADVMQRQSSAQLPSATAASLADTLDEMARMLAAGGYPLEIALQAAPIDNLSPVQQAVLRELVAAID
GYAEAGTDPSDAPARAAATPKSGFLSADAFTNPDHVRYALKTTGAAMFCYVLYQQLNWPGIHTCFITCYLVSLGTTAESV
EKLWLRLAGCLVGAVIGTAAIVYVVPSLSSIGGLMLLVFAGTWISAWVAQGSPRIAYAGFQIAFAFYLCVVQGAAPGFDL
TIARDRVIGVLLGNLVVYLVFTRIWPVSIAGRIESALAALVTQWQALVDTPQPTARRQHAAAALALHGTITQDLILAHYE
PASVGPAQEWVDIHRERLATLDAISGPMFLLAERFPGDPALAQRLHRLRTDIPLQTAPQHAEAIPDAPDDVRARQALLAI
VDQQLETSHADASDTGSPSSIHAQT

Sequences:

>Translated_665_residues
MAQPAADKLRLRLADIGALLAPLPGRYAGATRITVGCTLTVLVTSIYGTPEAAISAYVIFFINRADRTTSIIMSAAALVL
VSLIIALVVWLADFSVDDPMRRVTCMAVLSAVLLFLTSASKLRPVGAIVAMIIGFALDELGLVPGGEVATRALLYAWLMV
AIPIGVNIVVNLAMGPSPRRLATDRLAHCLRIAARCLRDPLDNGGGDALHEALHGGLQPVAGWLRLARVEGALNVQDLHA
LQQATASTLAILLAADVMQRQSSAQLPSATAASLADTLDEMARMLAAGGYPLEIALQAAPIDNLSPVQQAVLRELVAAID
GYAEAGTDPSDAPARAAATPKSGFLSADAFTNPDHVRYALKTTGAAMFCYVLYQQLNWPGIHTCFITCYLVSLGTTAESV
EKLWLRLAGCLVGAVIGTAAIVYVVPSLSSIGGLMLLVFAGTWISAWVAQGSPRIAYAGFQIAFAFYLCVVQGAAPGFDL
TIARDRVIGVLLGNLVVYLVFTRIWPVSIAGRIESALAALVTQWQALVDTPQPTARRQHAAAALALHGTITQDLILAHYE
PASVGPAQEWVDIHRERLATLDAISGPMFLLAERFPGDPALAQRLHRLRTDIPLQTAPQHAEAIPDAPDDVRARQALLAI
VDQQLETSHADASDTGSPSSIHAQT
>Mature_664_residues
AQPAADKLRLRLADIGALLAPLPGRYAGATRITVGCTLTVLVTSIYGTPEAAISAYVIFFINRADRTTSIIMSAAALVLV
SLIIALVVWLADFSVDDPMRRVTCMAVLSAVLLFLTSASKLRPVGAIVAMIIGFALDELGLVPGGEVATRALLYAWLMVA
IPIGVNIVVNLAMGPSPRRLATDRLAHCLRIAARCLRDPLDNGGGDALHEALHGGLQPVAGWLRLARVEGALNVQDLHAL
QQATASTLAILLAADVMQRQSSAQLPSATAASLADTLDEMARMLAAGGYPLEIALQAAPIDNLSPVQQAVLRELVAAIDG
YAEAGTDPSDAPARAAATPKSGFLSADAFTNPDHVRYALKTTGAAMFCYVLYQQLNWPGIHTCFITCYLVSLGTTAESVE
KLWLRLAGCLVGAVIGTAAIVYVVPSLSSIGGLMLLVFAGTWISAWVAQGSPRIAYAGFQIAFAFYLCVVQGAAPGFDLT
IARDRVIGVLLGNLVVYLVFTRIWPVSIAGRIESALAALVTQWQALVDTPQPTARRQHAAAALALHGTITQDLILAHYEP
ASVGPAQEWVDIHRERLATLDAISGPMFLLAERFPGDPALAQRLHRLRTDIPLQTAPQHAEAIPDAPDDVRARQALLAIV
DQQLETSHADASDTGSPSSIHAQT

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MdtO family [H]

Homologues:

Organism=Escherichia coli, GI87082367, Length=554, Percent_Identity=25.6317689530686, Blast_Score=140, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006726 [H]

Pfam domain/function: PF04632 FUSC [H]

EC number: NA

Molecular weight: Translated: 70361; Mature: 70230

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPAADKLRLRLADIGALLAPLPGRYAGATRITVGCTLTVLVTSIYGTPEAAISAYVIF
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHE
FINRADRTTSIIMSAAALVLVSLIIALVVWLADFSVDDPMRRVTCMAVLSAVLLFLTSAS
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCH
KLRPVGAIVAMIIGFALDELGLVPGGEVATRALLYAWLMVAIPIGVNIVVNLAMGPSPRR
HCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHH
LATDRLAHCLRIAARCLRDPLDNGGGDALHEALHGGLQPVAGWLRLARVEGALNVQDLHA
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHH
LQQATASTLAILLAADVMQRQSSAQLPSATAASLADTLDEMARMLAAGGYPLEIALQAAP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
IDNLSPVQQAVLRELVAAIDGYAEAGTDPSDAPARAAATPKSGFLSADAFTNPDHVRYAL
CCCCCHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHHEEHH
KTTGAAMFCYVLYQQLNWPGIHTCFITCYLVSLGTTAESVEKLWLRLAGCLVGAVIGTAA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IVYVVPSLSSIGGLMLLVFAGTWISAWVAQGSPRIAYAGFQIAFAFYLCVVQGAAPGFDL
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCCEE
TIARDRVIGVLLGNLVVYLVFTRIWPVSIAGRIESALAALVTQWQALVDTPQPTARRQHA
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AAALALHGTITQDLILAHYEPASVGPAQEWVDIHRERLATLDAISGPMFLLAERFPGDPA
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHH
LAQRLHRLRTDIPLQTAPQHAEAIPDAPDDVRARQALLAIVDQQLETSHADASDTGSPSS
HHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IHAQT
CCCCC
>Mature Secondary Structure 
AQPAADKLRLRLADIGALLAPLPGRYAGATRITVGCTLTVLVTSIYGTPEAAISAYVIF
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHE
FINRADRTTSIIMSAAALVLVSLIIALVVWLADFSVDDPMRRVTCMAVLSAVLLFLTSAS
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCH
KLRPVGAIVAMIIGFALDELGLVPGGEVATRALLYAWLMVAIPIGVNIVVNLAMGPSPRR
HCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHH
LATDRLAHCLRIAARCLRDPLDNGGGDALHEALHGGLQPVAGWLRLARVEGALNVQDLHA
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHH
LQQATASTLAILLAADVMQRQSSAQLPSATAASLADTLDEMARMLAAGGYPLEIALQAAP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
IDNLSPVQQAVLRELVAAIDGYAEAGTDPSDAPARAAATPKSGFLSADAFTNPDHVRYAL
CCCCCHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHHEEHH
KTTGAAMFCYVLYQQLNWPGIHTCFITCYLVSLGTTAESVEKLWLRLAGCLVGAVIGTAA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IVYVVPSLSSIGGLMLLVFAGTWISAWVAQGSPRIAYAGFQIAFAFYLCVVQGAAPGFDL
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCCEE
TIARDRVIGVLLGNLVVYLVFTRIWPVSIAGRIESALAALVTQWQALVDTPQPTARRQHA
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AAALALHGTITQDLILAHYEPASVGPAQEWVDIHRERLATLDAISGPMFLLAERFPGDPA
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHH
LAQRLHRLRTDIPLQTAPQHAEAIPDAPDDVRARQALLAIVDQQLETSHADASDTGSPSS
HHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IHAQT
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]