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The map label for this gene is oxlT [H]

Identifier: 73538159

GI number: 73538159

Start: 986739

End: 988055

Strand: Direct

Name: oxlT [H]

Synonym: Reut_B4329

Alternate gene names: 73538159

Gene position: 986739-988055 (Clockwise)

Preceding gene: 73538157

Following gene: 73538167

Centisome position: 36.2

GC content: 63.25

Gene sequence:

>1317_bases
ATGACTCATCCATCGGCAGCCCTCCCTTCGCAGCAAACTCCGGAAAACACGCGCTGGATCCAGCTGATTGTCGGCGTTGT
CTGCATGATTGCCACAGCGAACATCCAGTACGCGTGGACGCTGTTCGTGCCCGAGATCCAGGAAACCTATGGCTGGTCCC
GGGCCAGCATCCAGATCGCCTTTACGGTATTCGTGCTGGTCCAGACCTGGCTCGCACCGATCGAAGGCTATTTCATCGAC
AAGTTCGGGCCGCGCATGATGGTCGCGTTCGGCGCGGTGTTCATCGGCGCCGCGTGGGTCATCAACTCGCAGGCCACCAC
GCTGATGGGCTTCTACGTCGGCGCGGCGGTCGGCGGTCTTGGCGTGGGTTCGATCTACGCGACCTGCATCAACAACGCGC
TCAAGTGGTTCCCCGACCGGCGCGGCCTGGCCGTAGGCCTGACTGCGGGCGGCTATGGCGCGGGCTCGGCAGCCACCATC
CTGCCGATCGCTGCGATGATCGAGTCGTCGGGCTTCCAGCACACCTTCCTGTTCTTCGGCGTCCTGCAGGGCTCCCTGGC
GTTCGTCGCTGCGTGGTTCCTGCGCTCGCCGCAGGCCAATGAGGTCCGGGCTTCCCAGAAGCTCGTGCAGGCAACGCGCG
ACTACACGCTCAAGGAAGCGATGAGCACGAAGCTGTTCTGGCTGATGCTGGTGATGTTCGTGCTGGTCGTGACCGGCGGC
ATGATGGCCGTTGCGCAGCTCGGCGTCATTGCGAAGGACCTTGGCGTGAAGGAGTTCCAGGTCGACCTGCACTTCTTCGT
GATGGCCGCGCTGCCGCTCGCGCTGATGCTCGACCGCATCATGAACGGCATCTCGCGGCCACTGTTCGGCTGGATCTCGG
ACAACATCGGCCGCGAGAAAACCATGGTCATCGCGTTCTCGCTCGAAGGCCTCGGCATCATCGCGCTCGGCTACTTCGGC
AGCAATCCGTATGCGTTCCTGATCCTGTCCGGCGTGGTGTTCCTGGCCTGGGGCGAGGTGTATTCGCTGTTCTCGGCGCT
GGCGGGCGATGCCTTCGGCACGAAGCACATCGGCAAGATCTACGGCGTGCTTTATACGGCGAAGGGTATCGGCGCGCTAT
TTGTCCCGATTGGTAACCTGCTGATGGAGGCGACCGGCACGTGGTCGACGGTTCTCTACACAGTCGCCGCCATGGATCTT
AGCGCCGCATTCCTCGCGATGATGGTCCTGCGCCCCGTGCTGGCATCGCATGTAGCAACGGCCCGGAGCCTTCACTCTAA
GGAAACCGCGGCAGCCGGCGCTCGGGTTCCCGCCTGA

Upstream 100 bases:

>100_bases
AATAAGCAATGGAACAGGAGACATGAAAAATGAGAGCGACCTCACGAGAACCAGGCATTCACGCCGTCGGATTGCACCGA
TCCAATTCACGGAGCGCACA

Downstream 100 bases:

>100_bases
CGCTGGCGCGAAGTACAAGCGGGCTTCGTCGGAAGCCCGCTTGCTTTTGGGAATGGCGCAGCGCGCTCAGGTTTTGACTT
CGTGGCGCGCCAGACTTTTG

Product: major facilitator transporter

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MTHPSAALPSQQTPENTRWIQLIVGVVCMIATANIQYAWTLFVPEIQETYGWSRASIQIAFTVFVLVQTWLAPIEGYFID
KFGPRMMVAFGAVFIGAAWVINSQATTLMGFYVGAAVGGLGVGSIYATCINNALKWFPDRRGLAVGLTAGGYGAGSAATI
LPIAAMIESSGFQHTFLFFGVLQGSLAFVAAWFLRSPQANEVRASQKLVQATRDYTLKEAMSTKLFWLMLVMFVLVVTGG
MMAVAQLGVIAKDLGVKEFQVDLHFFVMAALPLALMLDRIMNGISRPLFGWISDNIGREKTMVIAFSLEGLGIIALGYFG
SNPYAFLILSGVVFLAWGEVYSLFSALAGDAFGTKHIGKIYGVLYTAKGIGALFVPIGNLLMEATGTWSTVLYTVAAMDL
SAAFLAMMVLRPVLASHVATARSLHSKETAAAGARVPA

Sequences:

>Translated_438_residues
MTHPSAALPSQQTPENTRWIQLIVGVVCMIATANIQYAWTLFVPEIQETYGWSRASIQIAFTVFVLVQTWLAPIEGYFID
KFGPRMMVAFGAVFIGAAWVINSQATTLMGFYVGAAVGGLGVGSIYATCINNALKWFPDRRGLAVGLTAGGYGAGSAATI
LPIAAMIESSGFQHTFLFFGVLQGSLAFVAAWFLRSPQANEVRASQKLVQATRDYTLKEAMSTKLFWLMLVMFVLVVTGG
MMAVAQLGVIAKDLGVKEFQVDLHFFVMAALPLALMLDRIMNGISRPLFGWISDNIGREKTMVIAFSLEGLGIIALGYFG
SNPYAFLILSGVVFLAWGEVYSLFSALAGDAFGTKHIGKIYGVLYTAKGIGALFVPIGNLLMEATGTWSTVLYTVAAMDL
SAAFLAMMVLRPVLASHVATARSLHSKETAAAGARVPA
>Mature_437_residues
THPSAALPSQQTPENTRWIQLIVGVVCMIATANIQYAWTLFVPEIQETYGWSRASIQIAFTVFVLVQTWLAPIEGYFIDK
FGPRMMVAFGAVFIGAAWVINSQATTLMGFYVGAAVGGLGVGSIYATCINNALKWFPDRRGLAVGLTAGGYGAGSAATIL
PIAAMIESSGFQHTFLFFGVLQGSLAFVAAWFLRSPQANEVRASQKLVQATRDYTLKEAMSTKLFWLMLVMFVLVVTGGM
MAVAQLGVIAKDLGVKEFQVDLHFFVMAALPLALMLDRIMNGISRPLFGWISDNIGREKTMVIAFSLEGLGIIALGYFGS
NPYAFLILSGVVFLAWGEVYSLFSALAGDAFGTKHIGKIYGVLYTAKGIGALFVPIGNLLMEATGTWSTVLYTVAAMDLS
AAFLAMMVLRPVLASHVATARSLHSKETAAAGARVPA

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=365, Percent_Identity=26.5753424657534, Blast_Score=131, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47028; Mature: 46897

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPSAALPSQQTPENTRWIQLIVGVVCMIATANIQYAWTLFVPEIQETYGWSRASIQIA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHCCCCHHHHHHH
FTVFVLVQTWLAPIEGYFIDKFGPRMMVAFGAVFIGAAWVINSQATTLMGFYVGAAVGGL
HHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHCCC
GVGSIYATCINNALKWFPDRRGLAVGLTAGGYGAGSAATILPIAAMIESSGFQHTFLFFG
CHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
VLQGSLAFVAAWFLRSPQANEVRASQKLVQATRDYTLKEAMSTKLFWLMLVMFVLVVTGG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
MMAVAQLGVIAKDLGVKEFQVDLHFFVMAALPLALMLDRIMNGISRPLFGWISDNIGREK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCE
TMVIAFSLEGLGIIALGYFGSNPYAFLILSGVVFLAWGEVYSLFSALAGDAFGTKHIGKI
EEEEEEEECCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YGVLYTAKGIGALFVPIGNLLMEATGTWSTVLYTVAAMDLSAAFLAMMVLRPVLASHVAT
HHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARSLHSKETAAAGARVPA
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
THPSAALPSQQTPENTRWIQLIVGVVCMIATANIQYAWTLFVPEIQETYGWSRASIQIA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHCCCCHHHHHHH
FTVFVLVQTWLAPIEGYFIDKFGPRMMVAFGAVFIGAAWVINSQATTLMGFYVGAAVGGL
HHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHCCC
GVGSIYATCINNALKWFPDRRGLAVGLTAGGYGAGSAATILPIAAMIESSGFQHTFLFFG
CHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
VLQGSLAFVAAWFLRSPQANEVRASQKLVQATRDYTLKEAMSTKLFWLMLVMFVLVVTGG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
MMAVAQLGVIAKDLGVKEFQVDLHFFVMAALPLALMLDRIMNGISRPLFGWISDNIGREK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCE
TMVIAFSLEGLGIIALGYFGSNPYAFLILSGVVFLAWGEVYSLFSALAGDAFGTKHIGKI
EEEEEEEECCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YGVLYTAKGIGALFVPIGNLLMEATGTWSTVLYTVAAMDLSAAFLAMMVLRPVLASHVAT
HHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARSLHSKETAAAGARVPA
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]