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The map label for this gene is cmpR [H]

Identifier: 73538118

GI number: 73538118

Start: 948773

End: 949660

Strand: Direct

Name: cmpR [H]

Synonym: Reut_B4288

Alternate gene names: 73538118

Gene position: 948773-949660 (Clockwise)

Preceding gene: 73538117

Following gene: 73538119

Centisome position: 34.8

GC content: 65.54

Gene sequence:

>888_bases
ATGCTCGGCGATCTTCTCACGACCTTTTTCGAAGTGGCTCGCCAGGGCAGCATTACCACGGCCGCGCGGCAGCTCGGCGT
CAGCCAGCCCACCGTTACGGCACGCATCCGCCAGCTGGAGGATGTCTATGGCGTGGAGCTGTTCTATCGCCGTGCGAGCC
GGGTCGACCTGAGCGATGTCGGTGTCGCGCTGATGCCCGTGGTGGAGCAGTTGATGCAACAGGAAAGCAATGCCGACTAT
CTCCTGCGCAATGCGGGGAACCTGCGCTTCGGTAATTTGCGCATCGGCGCAACCGGTCCGTATTACATCCTGCGCAGCGT
TGCCGCGTTCCGGCAGCGCTACCCGGCCGTCGAAGTCAGCATCGAGATCGGCAATTCGCAGCAGATGATCGAGGCGCTGC
TGGAATACCGCATCGACGCCGCGGTGTCCTCGCACGCGGTGGACGACAGCCGGCTCGCGCGTATCCGGCTGGCGAGCGAT
CCGATGGTGCTGGTCGTCCATCCGGAACACCCGTTCGCGCGGATGCCCCATATCGATATCGCCCGCCTTGCCGAATGCCA
CCTGCTCGTGCGCGAGCACGGGTCGATGACGCGGCAGGCCACCGAGGCTGCGCTCGCAGCATGCGGCCAGGAACTGCCGC
GCCATATGGTCATCGGCAGCCGCGAGGCCATCTACGAAGCGATCCGCCAGAACATTGGCGCGAGTGTCGTACCCGCTGGC
GAAGTCCCGCGCGATCCCTCGCTGCGCATTGTGCCGTTCGCGCAGCGCCCGCCCGTCATCCACGAGTACCTGTACTGCCT
GGAAAGCCGGCGGCATACGCGGCTGGTCGGCGCCCTTCTCGAATGCGTGGAATCGCTGGCGCCTCACCAGCAGGCTCAGG
CTGCCTGA

Upstream 100 bases:

>100_bases
CGAAAGTCGGGGAAAGCGTAGCGGTACTGTCACATTGCACCGATAGACTGCGCGCTAATCCGGTGCCTGCGCGTCCGCTA
CCTTTCCCTGCCCTCAACCC

Downstream 100 bases:

>100_bases
GTGATGCAGGGCACGCCCTGCCCCGCCCTCACGTGGCCGCGGCGTCGCTCAGCGCCTATATTGGTGCCATGAGCGAGCGC
ACCGCTTTTGCCGAATACGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MLGDLLTTFFEVARQGSITTAARQLGVSQPTVTARIRQLEDVYGVELFYRRASRVDLSDVGVALMPVVEQLMQQESNADY
LLRNAGNLRFGNLRIGATGPYYILRSVAAFRQRYPAVEVSIEIGNSQQMIEALLEYRIDAAVSSHAVDDSRLARIRLASD
PMVLVVHPEHPFARMPHIDIARLAECHLLVREHGSMTRQATEAALAACGQELPRHMVIGSREAIYEAIRQNIGASVVPAG
EVPRDPSLRIVPFAQRPPVIHEYLYCLESRRHTRLVGALLECVESLAPHQQAQAA

Sequences:

>Translated_295_residues
MLGDLLTTFFEVARQGSITTAARQLGVSQPTVTARIRQLEDVYGVELFYRRASRVDLSDVGVALMPVVEQLMQQESNADY
LLRNAGNLRFGNLRIGATGPYYILRSVAAFRQRYPAVEVSIEIGNSQQMIEALLEYRIDAAVSSHAVDDSRLARIRLASD
PMVLVVHPEHPFARMPHIDIARLAECHLLVREHGSMTRQATEAALAACGQELPRHMVIGSREAIYEAIRQNIGASVVPAG
EVPRDPSLRIVPFAQRPPVIHEYLYCLESRRHTRLVGALLECVESLAPHQQAQAA
>Mature_295_residues
MLGDLLTTFFEVARQGSITTAARQLGVSQPTVTARIRQLEDVYGVELFYRRASRVDLSDVGVALMPVVEQLMQQESNADY
LLRNAGNLRFGNLRIGATGPYYILRSVAAFRQRYPAVEVSIEIGNSQQMIEALLEYRIDAAVSSHAVDDSRLARIRLASD
PMVLVVHPEHPFARMPHIDIARLAECHLLVREHGSMTRQATEAALAACGQELPRHMVIGSREAIYEAIRQNIGASVVPAG
EVPRDPSLRIVPFAQRPPVIHEYLYCLESRRHTRLVGALLECVESLAPHQQAQAA

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=235, Percent_Identity=30.2127659574468, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI157672245, Length=265, Percent_Identity=27.9245283018868, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790399, Length=261, Percent_Identity=26.0536398467433, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI145693105, Length=262, Percent_Identity=23.2824427480916, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082132, Length=295, Percent_Identity=26.4406779661017, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787601, Length=170, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788296, Length=215, Percent_Identity=27.4418604651163, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788748, Length=247, Percent_Identity=24.2914979757085, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786401, Length=150, Percent_Identity=30, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787806, Length=164, Percent_Identity=29.2682926829268, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787879, Length=184, Percent_Identity=26.0869565217391, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787530, Length=285, Percent_Identity=24.5614035087719, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32752; Mature: 32752

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGDLLTTFFEVARQGSITTAARQLGVSQPTVTARIRQLEDVYGVELFYRRASRVDLSDV
CCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GVALMPVVEQLMQQESNADYLLRNAGNLRFGNLRIGATGPYYILRSVAAFRQRYPAVEVS
HHHHHHHHHHHHHCCCCCCEEEECCCCEEECCEEECCCCHHHHHHHHHHHHHHCCCEEEE
IEIGNSQQMIEALLEYRIDAAVSSHAVDDSRLARIRLASDPMVLVVHPEHPFARMPHIDI
EEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCEEEEECCCCCCCCCCCCHH
ARLAECHLLVREHGSMTRQATEAALAACGQELPRHMVIGSREAIYEAIRQNIGASVVPAG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCCCCCC
EVPRDPSLRIVPFAQRPPVIHEYLYCLESRRHTRLVGALLECVESLAPHQQAQAA
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MLGDLLTTFFEVARQGSITTAARQLGVSQPTVTARIRQLEDVYGVELFYRRASRVDLSDV
CCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GVALMPVVEQLMQQESNADYLLRNAGNLRFGNLRIGATGPYYILRSVAAFRQRYPAVEVS
HHHHHHHHHHHHHCCCCCCEEEECCCCEEECCEEECCCCHHHHHHHHHHHHHHCCCEEEE
IEIGNSQQMIEALLEYRIDAAVSSHAVDDSRLARIRLASDPMVLVVHPEHPFARMPHIDI
EEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCEEEEECCCCCCCCCCCCHH
ARLAECHLLVREHGSMTRQATEAALAACGQELPRHMVIGSREAIYEAIRQNIGASVVPAG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCCCCCC
EVPRDPSLRIVPFAQRPPVIHEYLYCLESRRHTRLVGALLECVESLAPHQQAQAA
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]