Click here to switch to the map view.

The map label for this gene is crt [H]

Identifier: 73538091

GI number: 73538091

Start: 918441

End: 919571

Strand: Direct

Name: crt [H]

Synonym: Reut_B4261

Alternate gene names: 73538091

Gene position: 918441-919571 (Clockwise)

Preceding gene: 73538090

Following gene: 73538097

Centisome position: 33.69

GC content: 66.93

Gene sequence:

>1131_bases
ATGCGACTGACACCTGAAATCGCGCCGGGCAGTTCACTGGCCGACACCGAGCCCGAAGTCCTGTTTCAGGTCATCAACCG
CGTCGGGTTGGTGACGCTGAACCGGCCGCGGCAGCTCAATGCGCTGTCCTACCCGATGATCGTGGCGCTGTCCGGTCAGC
TCGAAGCGTGGGCCGGGCGGGACGATATCGAGGCCGTGGTGCTGCGCGGCGCCGGACCCAAGGCCTTCTGCGCGGGTGGC
GATATCCGCGCGCTGTATGACAGCCATCGCGACGGCACGCCGCTGCAGCGCCAGTTCTTCATCGACGAATATCAGCTCGA
CTACCGGCTGCACCGCTATCCGAAGCCCGTGGTGGCGCTGATGGATGGCATCGTCATGGGCGGCGGCATGGGCCTGTCGC
AGGCCGCGCATCTGCGCGTCGTCACCGAGCGGTCGCGCGTGGCCATGCCGGAAACGGGAATCGGGCTTGTGCCCGATGTG
GGCGCCAGTCACTTCCTGTCGAAAATGCCGGTCCAGCTTGCGCTGTATCTCGGCCTGACTGGTGTGACCATTGGCGCAGA
GGATGCGCTGCTGTGCGGGCTGGCCGACGTCGCGGTCAACAGTGTCACGCTTGCCGCGCTCGACGATGCGCTGGCCGGCA
TCCGCTGGAGCGGGCAGCCGCTGGACGACGTGCGCCGTGCGCTGGTAGGCGAACCGATCTGCAGCGCGGCCGATGCACCG
CTGCTCGAGGTGCTGCCGGCCCTGCTGCGGCACTTCCCTGCTGATGCCGGGCTTCCGGAAATCATCGCGAGCCTGTCCTG
CCAGGACGATCCGCGCTACGCCGAATGGGCGACGCGGACGGCAGAAGCGCTGCGCAAGCGCTCGCCGCTGGCCGCCTGTG
CCACACGCGAACTGCTGCTGCGTGGCCGCCGGCTAGATCTGGCCGATTGCTTCCGCATGGAGCTTGCCGTAGTGGTGCAA
TCGTTCGCGCGCGGAGACTTCATCGAAGGCGTGCGCGCGCTGATCGTCGATAAGGACAATATGCCCCAATGGCGTATTGG
CAGCTACGACGCCGTGGATGCTGCAGCGGTAGAAGCGCTGTTTGCGCACTGGTGGCAGCCGGGCGCCGATCCGCTCCACA
TGCTGGGCTGA

Upstream 100 bases:

>100_bases
GCGCTTTGTCGACCTGTTCGACGGCGAGGACCAGCGCGAAGGCGTCAATGCCTTCCTGCAGAAGCGCGCGCCGCAGTGGC
GCAATGCGTAGGAGCGCATC

Downstream 100 bases:

>100_bases
TGGCTGGCGCCCGGGCGCCGCTTCTCGTCCCGACCTAGTGCCCGGCGCTGCGAATCGAGTCTGGCGAAAAGTAGGCCTCG
TTGAACTGGGGGCTGCTGTT

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MRLTPEIAPGSSLADTEPEVLFQVINRVGLVTLNRPRQLNALSYPMIVALSGQLEAWAGRDDIEAVVLRGAGPKAFCAGG
DIRALYDSHRDGTPLQRQFFIDEYQLDYRLHRYPKPVVALMDGIVMGGGMGLSQAAHLRVVTERSRVAMPETGIGLVPDV
GASHFLSKMPVQLALYLGLTGVTIGAEDALLCGLADVAVNSVTLAALDDALAGIRWSGQPLDDVRRALVGEPICSAADAP
LLEVLPALLRHFPADAGLPEIIASLSCQDDPRYAEWATRTAEALRKRSPLAACATRELLLRGRRLDLADCFRMELAVVVQ
SFARGDFIEGVRALIVDKDNMPQWRIGSYDAVDAAAVEALFAHWWQPGADPLHMLG

Sequences:

>Translated_376_residues
MRLTPEIAPGSSLADTEPEVLFQVINRVGLVTLNRPRQLNALSYPMIVALSGQLEAWAGRDDIEAVVLRGAGPKAFCAGG
DIRALYDSHRDGTPLQRQFFIDEYQLDYRLHRYPKPVVALMDGIVMGGGMGLSQAAHLRVVTERSRVAMPETGIGLVPDV
GASHFLSKMPVQLALYLGLTGVTIGAEDALLCGLADVAVNSVTLAALDDALAGIRWSGQPLDDVRRALVGEPICSAADAP
LLEVLPALLRHFPADAGLPEIIASLSCQDDPRYAEWATRTAEALRKRSPLAACATRELLLRGRRLDLADCFRMELAVVVQ
SFARGDFIEGVRALIVDKDNMPQWRIGSYDAVDAAAVEALFAHWWQPGADPLHMLG
>Mature_376_residues
MRLTPEIAPGSSLADTEPEVLFQVINRVGLVTLNRPRQLNALSYPMIVALSGQLEAWAGRDDIEAVVLRGAGPKAFCAGG
DIRALYDSHRDGTPLQRQFFIDEYQLDYRLHRYPKPVVALMDGIVMGGGMGLSQAAHLRVVTERSRVAMPETGIGLVPDV
GASHFLSKMPVQLALYLGLTGVTIGAEDALLCGLADVAVNSVTLAALDDALAGIRWSGQPLDDVRRALVGEPICSAADAP
LLEVLPALLRHFPADAGLPEIIASLSCQDDPRYAEWATRTAEALRKRSPLAACATRELLLRGRRLDLADCFRMELAVVVQ
SFARGDFIEGVRALIVDKDNMPQWRIGSYDAVDAAAVEALFAHWWQPGADPLHMLG

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=365, Percent_Identity=35.0684931506849, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI37594469, Length=306, Percent_Identity=34.9673202614379, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI194097323, Length=175, Percent_Identity=34.8571428571429, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI68989263, Length=236, Percent_Identity=32.2033898305085, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI31542718, Length=164, Percent_Identity=25.609756097561, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI20127408, Length=194, Percent_Identity=30.9278350515464, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787659, Length=213, Percent_Identity=30.5164319248826, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788682, Length=213, Percent_Identity=29.1079812206573, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI221142681, Length=232, Percent_Identity=27.1551724137931, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI87082183, Length=181, Percent_Identity=28.1767955801105, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25144157, Length=355, Percent_Identity=36.9014084507042, Blast_Score=220, Evalue=8e-58,
Organism=Caenorhabditis elegans, GI25144160, Length=355, Percent_Identity=36.9014084507042, Blast_Score=220, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI25145438, Length=177, Percent_Identity=31.0734463276836, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=170, Percent_Identity=28.2352941176471, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508951, Length=174, Percent_Identity=30.4597701149425, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=174, Percent_Identity=30.4597701149425, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=174, Percent_Identity=30.4597701149425, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17558304, Length=160, Percent_Identity=27.5, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=227, Percent_Identity=38.3259911894273, Blast_Score=153, Evalue=4e-38,
Organism=Drosophila melanogaster, GI28571730, Length=352, Percent_Identity=37.2159090909091, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI28571729, Length=352, Percent_Identity=37.2159090909091, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI20129971, Length=174, Percent_Identity=32.183908045977, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24653477, Length=174, Percent_Identity=32.183908045977, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24653139, Length=189, Percent_Identity=29.1005291005291, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19922422, Length=183, Percent_Identity=27.8688524590164, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 40676; Mature: 40676

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTPEIAPGSSLADTEPEVLFQVINRVGLVTLNRPRQLNALSYPMIVALSGQLEAWAGR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEECCCCCCCCCCCCEEEEECCCCCCCCCC
DDIEAVVLRGAGPKAFCAGGDIRALYDSHRDGTPLQRQFFIDEYQLDYRLHRYPKPVVAL
CCCEEEEEECCCCCEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
MDGIVMGGGMGLSQAAHLRVVTERSRVAMPETGIGLVPDVGASHFLSKMPVQLALYLGLT
HHHHHCCCCCCCCCHHHEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHH
GVTIGAEDALLCGLADVAVNSVTLAALDDALAGIRWSGQPLDDVRRALVGEPICSAADAP
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHCCCCCC
LLEVLPALLRHFPADAGLPEIIASLSCQDDPRYAEWATRTAEALRKRSPLAACATRELLL
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RGRRLDLADCFRMELAVVVQSFARGDFIEGVRALIVDKDNMPQWRIGSYDAVDAAAVEAL
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHHH
FAHWWQPGADPLHMLG
HHHHCCCCCCCHHHCC
>Mature Secondary Structure
MRLTPEIAPGSSLADTEPEVLFQVINRVGLVTLNRPRQLNALSYPMIVALSGQLEAWAGR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEECCCCCCCCCCCCEEEEECCCCCCCCCC
DDIEAVVLRGAGPKAFCAGGDIRALYDSHRDGTPLQRQFFIDEYQLDYRLHRYPKPVVAL
CCCEEEEEECCCCCEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
MDGIVMGGGMGLSQAAHLRVVTERSRVAMPETGIGLVPDVGASHFLSKMPVQLALYLGLT
HHHHHCCCCCCCCCHHHEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHH
GVTIGAEDALLCGLADVAVNSVTLAALDDALAGIRWSGQPLDDVRRALVGEPICSAADAP
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHCCCCCC
LLEVLPALLRHFPADAGLPEIIASLSCQDDPRYAEWATRTAEALRKRSPLAACATRELLL
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RGRRLDLADCFRMELAVVVQSFARGDFIEGVRALIVDKDNMPQWRIGSYDAVDAAAVEAL
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHHH
FAHWWQPGADPLHMLG
HHHHCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]