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The map label for this gene is ttuB [H]

Identifier: 73537952

GI number: 73537952

Start: 759901

End: 761238

Strand: Reverse

Name: ttuB [H]

Synonym: Reut_B4121

Alternate gene names: 73537952

Gene position: 761238-759901 (Counterclockwise)

Preceding gene: 73537953

Following gene: 73537951

Centisome position: 27.92

GC content: 58.89

Gene sequence:

>1338_bases
ATGACAACAATCTCCACCTCCGCGGCGCGTCAGCGCACTGCGGACATACACTCGAGCGACGAAGTCCGAAGTGTCTACGC
CAAGGTCACGCGGCGCATAATTCCGTTCCTTTTCATCTGCTATGTGTTTGCCTATCTGGACCGCGTAAACATTGGCTTTG
CCGCGCTCCAGATGAAGCATGACCTCGGCTTCTCAGATGCTGTCTACGGCCTTGGCGCCGGCATCTTCTTCATTGGCTAT
TTCCTGTTCGAGGTGCCCAGCAACCTGCTGCTCGAGAAAATTGGTGCACGCAAGACCATGATGCGCATCATGGTCGTATG
GGGCGTCATTTCGGCAAGTTTTGCCTTTATCACGAGCCCGACGCAGTTCTATGTGGCTCGCTTCTTCCTTGGCGCTTTCG
AGGCCGGGTTCTTTCCCGGCATCGTGCTCTACCTGACATACTGGTTTCCGCCCGCGATGCGGGGCAAGATCATTACGCTC
TTCATGTCGGCGATCGCGGTATCCGGCATCATCGGCGGCCCCTTGTCCGGCTGGATCATGACCAACCTCAGCGACACCTC
CGGACTGCATGGCTGGCAATGGCTATTCATCATCGAGGCGGTCCCGTCCGTCATCCTCGGCGTGCTCGTCCTCTTTGTGC
TCGCCGACAAGCCCGCCGATGCCAGTTGGTTGTCCGCCAGGGAACAAGAGGTTGTGGCACGCGAAGTAGGCGCCACGGAC
CCACATGGCCATGACCACTCCTTCCTGAAGACGCTGCGCGATCCGCGGCTGTATGCGTTGTCAGTGGTTTATTTCACGAT
TGCTGCGGGCCTTTACATCATCAGCTTCTGGCTTCCCGAAATGGTTCGCAGCTATCACGTGACCAACCCCTTGCACATCG
GCATCCTGACGATGATTCCCTATCTGATCACCACCGTCGGCATGGTGGTGGTCGGCAAGCATTCGGACAAGACGCGTGAA
CGCCGCTGGCACGTCGCGCTCGGCATGATCGTTGCCGCCATGGGCCTGGTGGCCGTGACGTTCGTGCATAGCAGCCTGCC
CGTCGCGTTGGCTGTGCTTTCGATCACTACGCTGGGCGTTCTGACCGCGATGCCCCTGTTCTGGACGATCCCGACCTCCT
ATCTTTCCAGCTCAGGTGCTGCGGGTGGTATCGCAATAATCAACAGTATCGGACTGATCGGAGGGTTCGCCAGCCCATCC
ATGCTCGGCCTGGTGAAGACCACGACGGGGTCGCTGGATTACGGCCTGTACACCTTCGCGGCAGCGCTGGTACTCGGGGC
AGTTCTCCTGCTTGCTGCCATGCCGCAGCATTTGCTGCGAGAGGAAATCGGCGGTTGA

Upstream 100 bases:

>100_bases
TCAGCTTTCGAGGCGGGGTGGAGACCTGTCGTGGATGCTCGCGACCAGACTCCCCTCGGAAGCCACCAACCTCACAACAA
TCTGAACGGATGACAGGATC

Downstream 100 bases:

>100_bases
ACTGCCGACTGACGTTTCAGGGCACGAGCAGCCGCCGTGTCCTGACCCTGTACAACCCTCTGCTGATGGGGCCCGTATGC
GAATTCTTGTTTTGGGTGCT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MTTISTSAARQRTADIHSSDEVRSVYAKVTRRIIPFLFICYVFAYLDRVNIGFAALQMKHDLGFSDAVYGLGAGIFFIGY
FLFEVPSNLLLEKIGARKTMMRIMVVWGVISASFAFITSPTQFYVARFFLGAFEAGFFPGIVLYLTYWFPPAMRGKIITL
FMSAIAVSGIIGGPLSGWIMTNLSDTSGLHGWQWLFIIEAVPSVILGVLVLFVLADKPADASWLSAREQEVVAREVGATD
PHGHDHSFLKTLRDPRLYALSVVYFTIAAGLYIISFWLPEMVRSYHVTNPLHIGILTMIPYLITTVGMVVVGKHSDKTRE
RRWHVALGMIVAAMGLVAVTFVHSSLPVALAVLSITTLGVLTAMPLFWTIPTSYLSSSGAAGGIAIINSIGLIGGFASPS
MLGLVKTTTGSLDYGLYTFAAALVLGAVLLLAAMPQHLLREEIGG

Sequences:

>Translated_445_residues
MTTISTSAARQRTADIHSSDEVRSVYAKVTRRIIPFLFICYVFAYLDRVNIGFAALQMKHDLGFSDAVYGLGAGIFFIGY
FLFEVPSNLLLEKIGARKTMMRIMVVWGVISASFAFITSPTQFYVARFFLGAFEAGFFPGIVLYLTYWFPPAMRGKIITL
FMSAIAVSGIIGGPLSGWIMTNLSDTSGLHGWQWLFIIEAVPSVILGVLVLFVLADKPADASWLSAREQEVVAREVGATD
PHGHDHSFLKTLRDPRLYALSVVYFTIAAGLYIISFWLPEMVRSYHVTNPLHIGILTMIPYLITTVGMVVVGKHSDKTRE
RRWHVALGMIVAAMGLVAVTFVHSSLPVALAVLSITTLGVLTAMPLFWTIPTSYLSSSGAAGGIAIINSIGLIGGFASPS
MLGLVKTTTGSLDYGLYTFAAALVLGAVLLLAAMPQHLLREEIGG
>Mature_444_residues
TTISTSAARQRTADIHSSDEVRSVYAKVTRRIIPFLFICYVFAYLDRVNIGFAALQMKHDLGFSDAVYGLGAGIFFIGYF
LFEVPSNLLLEKIGARKTMMRIMVVWGVISASFAFITSPTQFYVARFFLGAFEAGFFPGIVLYLTYWFPPAMRGKIITLF
MSAIAVSGIIGGPLSGWIMTNLSDTSGLHGWQWLFIIEAVPSVILGVLVLFVLADKPADASWLSAREQEVVAREVGATDP
HGHDHSFLKTLRDPRLYALSVVYFTIAAGLYIISFWLPEMVRSYHVTNPLHIGILTMIPYLITTVGMVVVGKHSDKTRER
RWHVALGMIVAAMGLVAVTFVHSSLPVALAVLSITTLGVLTAMPLFWTIPTSYLSSSGAAGGIAIINSIGLIGGFASPSM
LGLVKTTTGSLDYGLYTFAAALVLGAVLLLAAMPQHLLREEIGG

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=376, Percent_Identity=23.4042553191489, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI87082071, Length=414, Percent_Identity=34.5410628019324, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI87082320, Length=305, Percent_Identity=25.5737704918033, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789152, Length=425, Percent_Identity=22.8235294117647, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1789515, Length=450, Percent_Identity=24.4444444444444, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI2367379, Length=423, Percent_Identity=22.6950354609929, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115533556, Length=453, Percent_Identity=22.7373068432671, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI115533554, Length=373, Percent_Identity=23.8605898123324, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=240, Percent_Identity=27.9166666666667, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6321698, Length=324, Percent_Identity=24.0740740740741, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319876, Length=365, Percent_Identity=26.3013698630137, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319250, Length=304, Percent_Identity=25.6578947368421, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324410, Length=151, Percent_Identity=23.841059602649, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322612, Length=265, Percent_Identity=22.2641509433962, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323032, Length=246, Percent_Identity=24.7967479674797, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321502, Length=210, Percent_Identity=25.2380952380952, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI20130167, Length=428, Percent_Identity=21.9626168224299, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24584153, Length=381, Percent_Identity=22.3097112860892, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24639764, Length=370, Percent_Identity=24.0540540540541, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24583789, Length=385, Percent_Identity=23.1168831168831, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641682, Length=187, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24648416, Length=332, Percent_Identity=22.5903614457831, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356189, Length=332, Percent_Identity=22.5903614457831, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48378; Mature: 48246

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTISTSAARQRTADIHSSDEVRSVYAKVTRRIIPFLFICYVFAYLDRVNIGFAALQMKH
CCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DLGFSDAVYGLGAGIFFIGYFLFEVPSNLLLEKIGARKTMMRIMVVWGVISASFAFITSP
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TQFYVARFFLGAFEAGFFPGIVLYLTYWFPPAMRGKIITLFMSAIAVSGIIGGPLSGWIM
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
TNLSDTSGLHGWQWLFIIEAVPSVILGVLVLFVLADKPADASWLSAREQEVVAREVGATD
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
PHGHDHSFLKTLRDPRLYALSVVYFTIAAGLYIISFWLPEMVRSYHVTNPLHIGILTMIP
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
YLITTVGMVVVGKHSDKTRERRWHVALGMIVAAMGLVAVTFVHSSLPVALAVLSITTLGV
HHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTAMPLFWTIPTSYLSSSGAAGGIAIINSIGLIGGFASPSMLGLVKTTTGSLDYGLYTFA
HHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHEEEEECCCCCHHHHHHHH
AALVLGAVLLLAAMPQHLLREEIGG
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTISTSAARQRTADIHSSDEVRSVYAKVTRRIIPFLFICYVFAYLDRVNIGFAALQMKH
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]