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The map label for this gene is tcp [H]

Identifier: 73537834

GI number: 73537834

Start: 639397

End: 641154

Strand: Direct

Name: tcp [H]

Synonym: Reut_B4001

Alternate gene names: 73537834

Gene position: 639397-641154 (Clockwise)

Preceding gene: 73537831

Following gene: 73537837

Centisome position: 23.45

GC content: 65.7

Gene sequence:

>1758_bases
ATGAAGACACTGACCCTGAACCAACGGCTCTGGATCCCCTTTGGCCTGATCTGGATCGCCATGCTCGGCATCTGTACGTA
CGAGGCGTTCGTCACGCGCGCGGAAATGTTCGCCGGACGCCAACGAGAAATCCAGAGCGTTGCGGAGGCCTCGGTCAGCC
TGGTCGCCGCCATCGAAAAAGAAGCGGCAAGCGAGGGCCTGTCCGTCGAAGAGGCACAGAAGCTGGCCAAGGAGCGCCTG
CGGCCGCTGCGCTTTGGGACGGACGGCTATGTTTCGATCACGGATTTCTCGGGCCGCTCGCTGATGCATCCGTTCAAGCC
CGAGAACGAAGGCAAGAACCTCAGCACGATGAAGGATCCGAACGGTGTGCTGATCTACGTGGAGATCGCGAAGATCGCCA
GCGGCCAGGGCGCGGGCTTCCTGAACTACATGTGGCCGAAGCCGGGCGCGAGCCAGCCGCTGCCCAAGGTCAGCTACGTC
AAGGCATTCAAGACGTGGGAGTGGACCGTTACCACGGGCGCCTATGTCGATGACATCGAGGCGGCGTTCCGCCAGGCGTT
GTTGCACTCCATCCTGACGCTGGTCATCCTGGGCGGTGCGGCGACGGTACTGGCCGCGTGGCTGCTGCGCGGCGTGCGCC
GCGACCTGGGTGGCGAGCCCGCCTATGCAGCGTCGGTCGCCAACAGCATTGCGGATGGCGATTTCACGCGCGATATCGAC
GTGCGCCCCGGTGACACCTCGAGCCTGCTCTTTGCCATGCAGCGCATGCAGCGCAAGCTGGGGGGCACCGTGAGCGGCAT
CCGTGCATCGGTCGATTCAGTGGCCACGGCCACGGCGCAGATTGCCGCCGGCAATTCGGACCTGTCGTCGCGCACCGAAC
AGCAGGCAGCGTCGCTGCAGGAAACGGCCGCGAGCATGGAAGAGCTGACCACGACCGTGCAGCACAATGCCGACAGCGCG
CGGCAGGCAAGCGGGCTGGCCGACAACGCGTCGGAGATCGCCAACCGCGGCGGCGAGGTGATGGAGCAGGTCATCACCAC
CATGACGCAGATCGCCGACAGTTCCAGTCAGATTGCGGACATCATCGGCGTGATTGAAGGCATTGCGTTCCAGACCAATA
TCCTGGCGCTCAATGCCGCGGTGGAGGCGGCGCGCGCGGGCGAACAGGGCCGGGGCTTCGCCGTGGTCGCGGGCGAAGTG
CGCAGCCTTGCCCAGCGCTCGGCAGGCGCTGCGAAGGAAATCCGCACGCTGATCAGCACGTCGGTCGATCGCGTGCGCAG
CGGTTCGGACCTCGTGGAGCGTGCGGGTTCGACCATGACGGAGATCACGCAGTCGATCCGCCGCGTGACCGATATCATGG
GCGAGATTGCCGCGGCGTCGGTGGAGCAACGCACCGGTATCGAGCAGGTCAACCAGGCCGTGGCCCAGATGGACCAGGTG
ACCCAGCAGAATGCCGCGCTTGTCGAAGAAGCTACTGCAGCCGCGCATTCGCTGGAAGAACAAGCTGCCGCGCTGCGCCA
GTCCGTGGCGGCATTCCGGGTCGCGCAACATGGCGGCGGCGGCGCCGCCGTCGTGCACCAGCCGGCTCCGGCACCGCGCC
GGCCGGCCGCGCCGAAGGCTGAGCCGGTCCTGCCACAAGTACCGAAAGCACCGAAAGCACCGAAAGCACCGAAAGCACTG
AAAGCACTGAAAGCGCAGCCGGCCCGTGCTGCACGCACCGAAAGCGCCGACGCTGGCGACAACTGGGAACAGTTCTGA

Upstream 100 bases:

>100_bases
TTGGTCTGACATTCCGTTGCTTGCAGGCTGGAGGCATTGTCGTTCGGGGATACGGCCCCGTCCCAATGGCCTGTCAGACG
CCCCCCACATCGCAACTGTA

Downstream 100 bases:

>100_bases
GCGCCGGTTGCTAGCGCGGTTGCGTGGCCGATGACGCCGGCGTGTCCGGTGTCTCGCCCGCAGCGGCGGCGACGGACGGC
ATCAACTGGAGTTCATGCCG

Product: histidine kinase

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MKTLTLNQRLWIPFGLIWIAMLGICTYEAFVTRAEMFAGRQREIQSVAEASVSLVAAIEKEAASEGLSVEEAQKLAKERL
RPLRFGTDGYVSITDFSGRSLMHPFKPENEGKNLSTMKDPNGVLIYVEIAKIASGQGAGFLNYMWPKPGASQPLPKVSYV
KAFKTWEWTVTTGAYVDDIEAAFRQALLHSILTLVILGGAATVLAAWLLRGVRRDLGGEPAYAASVANSIADGDFTRDID
VRPGDTSSLLFAMQRMQRKLGGTVSGIRASVDSVATATAQIAAGNSDLSSRTEQQAASLQETAASMEELTTTVQHNADSA
RQASGLADNASEIANRGGEVMEQVITTMTQIADSSSQIADIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEV
RSLAQRSAGAAKEIRTLISTSVDRVRSGSDLVERAGSTMTEITQSIRRVTDIMGEIAAASVEQRTGIEQVNQAVAQMDQV
TQQNAALVEEATAAAHSLEEQAAALRQSVAAFRVAQHGGGGAAVVHQPAPAPRRPAAPKAEPVLPQVPKAPKAPKAPKAL
KALKAQPARAARTESADAGDNWEQF

Sequences:

>Translated_585_residues
MKTLTLNQRLWIPFGLIWIAMLGICTYEAFVTRAEMFAGRQREIQSVAEASVSLVAAIEKEAASEGLSVEEAQKLAKERL
RPLRFGTDGYVSITDFSGRSLMHPFKPENEGKNLSTMKDPNGVLIYVEIAKIASGQGAGFLNYMWPKPGASQPLPKVSYV
KAFKTWEWTVTTGAYVDDIEAAFRQALLHSILTLVILGGAATVLAAWLLRGVRRDLGGEPAYAASVANSIADGDFTRDID
VRPGDTSSLLFAMQRMQRKLGGTVSGIRASVDSVATATAQIAAGNSDLSSRTEQQAASLQETAASMEELTTTVQHNADSA
RQASGLADNASEIANRGGEVMEQVITTMTQIADSSSQIADIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEV
RSLAQRSAGAAKEIRTLISTSVDRVRSGSDLVERAGSTMTEITQSIRRVTDIMGEIAAASVEQRTGIEQVNQAVAQMDQV
TQQNAALVEEATAAAHSLEEQAAALRQSVAAFRVAQHGGGGAAVVHQPAPAPRRPAAPKAEPVLPQVPKAPKAPKAPKAL
KALKAQPARAARTESADAGDNWEQF
>Mature_585_residues
MKTLTLNQRLWIPFGLIWIAMLGICTYEAFVTRAEMFAGRQREIQSVAEASVSLVAAIEKEAASEGLSVEEAQKLAKERL
RPLRFGTDGYVSITDFSGRSLMHPFKPENEGKNLSTMKDPNGVLIYVEIAKIASGQGAGFLNYMWPKPGASQPLPKVSYV
KAFKTWEWTVTTGAYVDDIEAAFRQALLHSILTLVILGGAATVLAAWLLRGVRRDLGGEPAYAASVANSIADGDFTRDID
VRPGDTSSLLFAMQRMQRKLGGTVSGIRASVDSVATATAQIAAGNSDLSSRTEQQAASLQETAASMEELTTTVQHNADSA
RQASGLADNASEIANRGGEVMEQVITTMTQIADSSSQIADIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEV
RSLAQRSAGAAKEIRTLISTSVDRVRSGSDLVERAGSTMTEITQSIRRVTDIMGEIAAASVEQRTGIEQVNQAVAQMDQV
TQQNAALVEEATAAAHSLEEQAAALRQSVAAFRVAQHGGGGAAVVHQPAPAPRRPAAPKAEPVLPQVPKAPKAPKAPKAL
KALKAQPARAARTESADAGDNWEQF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=346, Percent_Identity=56.9364161849711, Blast_Score=312, Evalue=4e-86,
Organism=Escherichia coli, GI2367378, Length=411, Percent_Identity=51.338199513382, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI1788194, Length=291, Percent_Identity=60.8247422680412, Blast_Score=307, Evalue=2e-84,
Organism=Escherichia coli, GI1787690, Length=337, Percent_Identity=52.2255192878338, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI1789453, Length=250, Percent_Identity=44, Blast_Score=201, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 61986; Mature: 61986

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLTLNQRLWIPFGLIWIAMLGICTYEAFVTRAEMFAGRQREIQSVAEASVSLVAAIEK
CCCEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
EAASEGLSVEEAQKLAKERLRPLRFGTDGYVSITDFSGRSLMHPFKPENEGKNLSTMKDP
HHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
NGVLIYVEIAKIASGQGAGFLNYMWPKPGASQPLPKVSYVKAFKTWEWTVTTGAYVDDIE
CCEEEEEEEEHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHCEEEEEECCCHHHHHH
AAFRQALLHSILTLVILGGAATVLAAWLLRGVRRDLGGEPAYAASVANSIADGDFTRDID
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC
VRPGDTSSLLFAMQRMQRKLGGTVSGIRASVDSVATATAQIAAGNSDLSSRTEQQAASLQ
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ETAASMEELTTTVQHNADSARQASGLADNASEIANRGGEVMEQVITTMTQIADSSSQIAD
HHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHH
IIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSAGAAKEIRTLIST
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHH
SVDRVRSGSDLVERAGSTMTEITQSIRRVTDIMGEIAAASVEQRTGIEQVNQAVAQMDQV
HHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TQQNAALVEEATAAAHSLEEQAAALRQSVAAFRVAQHGGGGAAVVHQPAPAPRRPAAPKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCC
EPVLPQVPKAPKAPKAPKALKALKAQPARAARTESADAGDNWEQF
CCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTLTLNQRLWIPFGLIWIAMLGICTYEAFVTRAEMFAGRQREIQSVAEASVSLVAAIEK
CCCEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
EAASEGLSVEEAQKLAKERLRPLRFGTDGYVSITDFSGRSLMHPFKPENEGKNLSTMKDP
HHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
NGVLIYVEIAKIASGQGAGFLNYMWPKPGASQPLPKVSYVKAFKTWEWTVTTGAYVDDIE
CCEEEEEEEEHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHCEEEEEECCCHHHHHH
AAFRQALLHSILTLVILGGAATVLAAWLLRGVRRDLGGEPAYAASVANSIADGDFTRDID
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC
VRPGDTSSLLFAMQRMQRKLGGTVSGIRASVDSVATATAQIAAGNSDLSSRTEQQAASLQ
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ETAASMEELTTTVQHNADSARQASGLADNASEIANRGGEVMEQVITTMTQIADSSSQIAD
HHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHH
IIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSAGAAKEIRTLIST
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHH
SVDRVRSGSDLVERAGSTMTEITQSIRRVTDIMGEIAAASVEQRTGIEQVNQAVAQMDQV
HHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TQQNAALVEEATAAAHSLEEQAAALRQSVAAFRVAQHGGGGAAVVHQPAPAPRRPAAPKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCC
EPVLPQVPKAPKAPKAPKALKALKAQPARAARTESADAGDNWEQF
CCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]