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The map label for this gene is benK [H]

Identifier: 73537772

GI number: 73537772

Start: 570052

End: 571422

Strand: Direct

Name: benK [H]

Synonym: Reut_B3938

Alternate gene names: 73537772

Gene position: 570052-571422 (Clockwise)

Preceding gene: 73537771

Following gene: 73537780

Centisome position: 20.91

GC content: 65.57

Gene sequence:

>1371_bases
GTGAGACAGATCGATGTGTACGCAGTGGCGGACGGCGCCACCTTCAACCGCTTCCATGCAGGCGTGCTGTTCTGGTGCGC
GCTGATCATCATTTTCGACGGCTATGACCTGGCAGTGGCCGGCATCGCTTTGCCGGCAATCATGAAGGACATGGGGGTGT
CGGCGACGCACGCGGGCTTCATGGTCAGCTCGGCGTTGTTCGGCATGATGTTTGGGGCCATCTTCCTCGGCACGATTGCC
GACCGCATCGGCCGGCGCAAGGCCATTGCCATCTGCATCCTGCTGTTCAGCGTGTTCACCGCCGCGGCGGGCATGACCAG
CGATCCGATGCTGTTCGCCGCGAGTCGTTTCCTGGCCGGGCTCGGCATCGGCGGGGTCATGCCCAATGTGGTGGCGCAGA
TGACCGAGTACTCGCCACGGCGTATCCGCGGCACGCTCGTGACGCTGATGTTCAGCGGCTACTCTGTCGGCGGCATGCTG
GCCGCGCTGCTCGGCAAGCAACTGCTCGAACAGTACGGCTGGCAGTCGGTGTTCCTGGCCGCTGGTGCACCGGCGCTGCT
GGTGCCGCTGATCCTCAGCAAACTGCCTGACTCCATGCCATTCCTGCTGCGCACCGGACAAAACGACACCGTGCGCAAGA
TCCTGCGCGCCATCGATCCGGCGAACCCTTGCAAGGATGGTGACCGCCTCGTGCTGCCGGACGCCAGCACGGGTGGCCAG
GCTGCTGTGGGCGAGCTGTTCCGCGAAGGGCGCGGCTTCAGCACGCTGATGTTCTGGCTGGCCTTCTTCATGTGCCTGTT
CATGGTCTACGCGCTCAGTTCGTGGCTGACCAAGCTGATGGCGTCGGCCGGCTACAGCCTGGGCTCTGCGCTGACCTTCG
TGCTGGTGCTGAATATCGGCGGCATGCTCGGCGCCATTGGCGGCGGCTGGCTGGCTGATCGCTTCAGCATCAAGTACGTG
CTGATGGGCATGTATGCGCTGGCCGCGGTGTCGATCGCGCTGCTCGGTTACAAGGTGCCCACGCCGGTGCTGTTCCTGCT
GGTGGGCCTGGCCGGTGCGTCGACCATCGGCACGCAGATCGTCACCTATGCGTATGCGGGGCAGTTCTACCCGGTGGCCG
CGCGATCGACGGGCATTGGCTGGGCGTCGGGCGTGGGACGTGCCGGGGCCATCCTTGCGCCGATCGTGATCGGTGTGCTG
GTAGGCATGGCTTTGCCGCTCGAGCAGAACTTCCTGGCGATCGCGGTACCGGCTGTGGTGGCCGTGCTGGCGGTGGGCGG
CATCGACCATCGGCGCGCCGCATCGGTGGGCGCGGTGCCGTCAGAACAGGTTGCGCCGAAGGTCTACGCAGCCTCGCGCG
CTGAGGGTTGA

Upstream 100 bases:

>100_bases
CCGCGCCACTCCTATTCTCCACGCCAGAAGACGTGCCGCCGGCAACGTCGCGGCGATCCCGACGCAAGAAGCGGGACTTT
TGGACAACTGGAGACAGGTA

Downstream 100 bases:

>100_bases
TTTCCGTTACGACCGTGTGCCGGCCACCGCGCCGGCCAGCCGGCCCAGCGTGGCCAGCGCGGTCTCGGCACGCTTGTCCC
ATTCGTGTCCGTAGTTGAGC

Product: major facilitator transporter

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MRQIDVYAVADGATFNRFHAGVLFWCALIIIFDGYDLAVAGIALPAIMKDMGVSATHAGFMVSSALFGMMFGAIFLGTIA
DRIGRRKAIAICILLFSVFTAAAGMTSDPMLFAASRFLAGLGIGGVMPNVVAQMTEYSPRRIRGTLVTLMFSGYSVGGML
AALLGKQLLEQYGWQSVFLAAGAPALLVPLILSKLPDSMPFLLRTGQNDTVRKILRAIDPANPCKDGDRLVLPDASTGGQ
AAVGELFREGRGFSTLMFWLAFFMCLFMVYALSSWLTKLMASAGYSLGSALTFVLVLNIGGMLGAIGGGWLADRFSIKYV
LMGMYALAAVSIALLGYKVPTPVLFLLVGLAGASTIGTQIVTYAYAGQFYPVAARSTGIGWASGVGRAGAILAPIVIGVL
VGMALPLEQNFLAIAVPAVVAVLAVGGIDHRRAASVGAVPSEQVAPKVYAASRAEG

Sequences:

>Translated_456_residues
MRQIDVYAVADGATFNRFHAGVLFWCALIIIFDGYDLAVAGIALPAIMKDMGVSATHAGFMVSSALFGMMFGAIFLGTIA
DRIGRRKAIAICILLFSVFTAAAGMTSDPMLFAASRFLAGLGIGGVMPNVVAQMTEYSPRRIRGTLVTLMFSGYSVGGML
AALLGKQLLEQYGWQSVFLAAGAPALLVPLILSKLPDSMPFLLRTGQNDTVRKILRAIDPANPCKDGDRLVLPDASTGGQ
AAVGELFREGRGFSTLMFWLAFFMCLFMVYALSSWLTKLMASAGYSLGSALTFVLVLNIGGMLGAIGGGWLADRFSIKYV
LMGMYALAAVSIALLGYKVPTPVLFLLVGLAGASTIGTQIVTYAYAGQFYPVAARSTGIGWASGVGRAGAILAPIVIGVL
VGMALPLEQNFLAIAVPAVVAVLAVGGIDHRRAASVGAVPSEQVAPKVYAASRAEG
>Mature_456_residues
MRQIDVYAVADGATFNRFHAGVLFWCALIIIFDGYDLAVAGIALPAIMKDMGVSATHAGFMVSSALFGMMFGAIFLGTIA
DRIGRRKAIAICILLFSVFTAAAGMTSDPMLFAASRFLAGLGIGGVMPNVVAQMTEYSPRRIRGTLVTLMFSGYSVGGML
AALLGKQLLEQYGWQSVFLAAGAPALLVPLILSKLPDSMPFLLRTGQNDTVRKILRAIDPANPCKDGDRLVLPDASTGGQ
AAVGELFREGRGFSTLMFWLAFFMCLFMVYALSSWLTKLMASAGYSLGSALTFVLVLNIGGMLGAIGGGWLADRFSIKYV
LMGMYALAAVSIALLGYKVPTPVLFLLVGLAGASTIGTQIVTYAYAGQFYPVAARSTGIGWASGVGRAGAILAPIVIGVL
VGMALPLEQNFLAIAVPAVVAVLAVGGIDHRRAASVGAVPSEQVAPKVYAASRAEG

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=448, Percent_Identity=22.9910714285714, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI7662270, Length=228, Percent_Identity=27.6315789473684, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI73695465, Length=219, Percent_Identity=28.310502283105, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI216548223, Length=219, Percent_Identity=29.2237442922374, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI166064021, Length=338, Percent_Identity=25.4437869822485, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI262399383, Length=168, Percent_Identity=27.9761904761905, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI213021148, Length=453, Percent_Identity=21.6335540838852, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI87081723, Length=379, Percent_Identity=30.3430079155673, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786229, Length=391, Percent_Identity=25.5754475703325, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI87082159, Length=389, Percent_Identity=29.5629820051414, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082404, Length=379, Percent_Identity=23.4828496042216, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082231, Length=185, Percent_Identity=24.8648648648649, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788074, Length=363, Percent_Identity=28.9256198347107, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788068, Length=462, Percent_Identity=24.2424242424242, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790463, Length=221, Percent_Identity=27.1493212669683, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=418, Percent_Identity=23.444976076555, Blast_Score=106, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320595, Length=193, Percent_Identity=27.4611398963731, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24640198, Length=231, Percent_Identity=26.4069264069264, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640196, Length=231, Percent_Identity=26.4069264069264, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640200, Length=231, Percent_Identity=26.4069264069264, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19922874, Length=412, Percent_Identity=22.0873786407767, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19922616, Length=357, Percent_Identity=23.8095238095238, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47727; Mature: 47727

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS00120 LIPASE_SER ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQIDVYAVADGATFNRFHAGVLFWCALIIIFDGYDLAVAGIALPAIMKDMGVSATHAGF
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHH
MVSSALFGMMFGAIFLGTIADRIGRRKAIAICILLFSVFTAAAGMTSDPMLFAASRFLAG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LGIGGVMPNVVAQMTEYSPRRIRGTLVTLMFSGYSVGGMLAALLGKQLLEQYGWQSVFLA
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEHH
AGAPALLVPLILSKLPDSMPFLLRTGQNDTVRKILRAIDPANPCKDGDRLVLPDASTGGQ
CCCHHHHHHHHHHHCCCCCCHHEECCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCH
AAVGELFREGRGFSTLMFWLAFFMCLFMVYALSSWLTKLMASAGYSLGSALTFVLVLNIG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
GMLGAIGGGWLADRFSIKYVLMGMYALAAVSIALLGYKVPTPVLFLLVGLAGASTIGTQI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHH
VTYAYAGQFYPVAARSTGIGWASGVGRAGAILAPIVIGVLVGMALPLEQNFLAIAVPAVV
HHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AVLAVGGIDHRRAASVGAVPSEQVAPKVYAASRAEG
HHHHHCCCCHHHHHCCCCCCCHHHCCHHHHHCCCCC
>Mature Secondary Structure
MRQIDVYAVADGATFNRFHAGVLFWCALIIIFDGYDLAVAGIALPAIMKDMGVSATHAGF
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHH
MVSSALFGMMFGAIFLGTIADRIGRRKAIAICILLFSVFTAAAGMTSDPMLFAASRFLAG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LGIGGVMPNVVAQMTEYSPRRIRGTLVTLMFSGYSVGGMLAALLGKQLLEQYGWQSVFLA
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEHH
AGAPALLVPLILSKLPDSMPFLLRTGQNDTVRKILRAIDPANPCKDGDRLVLPDASTGGQ
CCCHHHHHHHHHHHCCCCCCHHEECCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCH
AAVGELFREGRGFSTLMFWLAFFMCLFMVYALSSWLTKLMASAGYSLGSALTFVLVLNIG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
GMLGAIGGGWLADRFSIKYVLMGMYALAAVSIALLGYKVPTPVLFLLVGLAGASTIGTQI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHH
VTYAYAGQFYPVAARSTGIGWASGVGRAGAILAPIVIGVLVGMALPLEQNFLAIAVPAVV
HHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AVLAVGGIDHRRAASVGAVPSEQVAPKVYAASRAEG
HHHHHCCCCHHHHHCCCCCCCHHHCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]