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The map label for this gene is paaG [C]

Identifier: 73537443

GI number: 73537443

Start: 170699

End: 171574

Strand: Reverse

Name: paaG [C]

Synonym: Reut_B3608

Alternate gene names: 73537443

Gene position: 171574-170699 (Counterclockwise)

Preceding gene: 73537447

Following gene: 73537442

Centisome position: 6.29

GC content: 67.92

Gene sequence:

>876_bases
ATGACCCCATCGAATCCCACTTTCGAGACCCTGTGCTATGCCGTGGAAGACGGCGTAGCCACCATCACACTGCACCGGCC
CGACCAGCTCAACGCGTTCACGGGCCAGATGATGCAGGACCTGATCGCCGCCTTTGATGCTACCGATGCCGATGACAACG
TGCGCGCGGTCATCGTCACGGGCTCCGGCCGAGCCTTCTGCGCCGGCGCGGACCTATCGGCCGGCGGCGCCACCTTCGAT
TTCGAGAAGCGCTATGGCGCGAAGCCCGAGACGGCCCACCGCGACGGCGGCGGCCGCGTGTCGCTGCGCATCTTCCGCAG
CCTGAAGCCGGTGATCGCCGCCGTGAATGGCGCCGCGGTCGGTGTGGGCGTCACCATGCAACTGCCCATGGATATCCGGC
TGGCGTCCACCGACGCGAAGTTCGGCTTCGTGTTCGCGCGCCGCGGCATCACGCCGGAGGCAGCGTCGTCGTGGTTCCTG
TCGCGCGTCGTGGGAATCTCGACTGCGCTCGAATGGTGCTACACGGGTCGCGTGTTCTCGGCGCAGGAAGCGCTCGAGCG
CGGCCTCGTGCGCTCGCTCCATGCGCCGGAAGACCTGCTGCCCGCCGCACGCGCGATCGCACGGGAGATTGCCGACAACG
CCGCGCCGGTGTCCGTCGCCATCTCGCGCCAGTTGATCTGGCGCATGGCCGGTGCCAGCCACCCGATGGAAGCACACAAG
CTCGACAGCCGCGCGATCCAGTCGCGCGGCCGCTCGGCCGACGTCAAGGAAGGCGTCAGCGCATTTCTGGAAAAGCGTCC
CGCCGCCTTCCCCGAACGTGTGTCGCAAGACATGCCGGACTTCTTCGACTGGGGCGGCGAGCCCCCATTCGCCTGA

Upstream 100 bases:

>100_bases
TCTAAGATGCCGCCGTGCGCGCCAGCTTCGTCGGAAGCGACGATTGCGGGAGACGCATTCTGCACTAGTGTGGACCGAAT
CATCCCGCCGCCCGACGACC

Downstream 100 bases:

>100_bases
GCAGGAGCCGACATGAAGGTCAGTCAAGCGGTGGAGAGCCGCAAATCCGTGCGCGGCTTTTTGCCTAATCCCATCGATCC
CGACACCATCCGCCGAGTGC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MTPSNPTFETLCYAVEDGVATITLHRPDQLNAFTGQMMQDLIAAFDATDADDNVRAVIVTGSGRAFCAGADLSAGGATFD
FEKRYGAKPETAHRDGGGRVSLRIFRSLKPVIAAVNGAAVGVGVTMQLPMDIRLASTDAKFGFVFARRGITPEAASSWFL
SRVVGISTALEWCYTGRVFSAQEALERGLVRSLHAPEDLLPAARAIAREIADNAAPVSVAISRQLIWRMAGASHPMEAHK
LDSRAIQSRGRSADVKEGVSAFLEKRPAAFPERVSQDMPDFFDWGGEPPFA

Sequences:

>Translated_291_residues
MTPSNPTFETLCYAVEDGVATITLHRPDQLNAFTGQMMQDLIAAFDATDADDNVRAVIVTGSGRAFCAGADLSAGGATFD
FEKRYGAKPETAHRDGGGRVSLRIFRSLKPVIAAVNGAAVGVGVTMQLPMDIRLASTDAKFGFVFARRGITPEAASSWFL
SRVVGISTALEWCYTGRVFSAQEALERGLVRSLHAPEDLLPAARAIAREIADNAAPVSVAISRQLIWRMAGASHPMEAHK
LDSRAIQSRGRSADVKEGVSAFLEKRPAAFPERVSQDMPDFFDWGGEPPFA
>Mature_290_residues
TPSNPTFETLCYAVEDGVATITLHRPDQLNAFTGQMMQDLIAAFDATDADDNVRAVIVTGSGRAFCAGADLSAGGATFDF
EKRYGAKPETAHRDGGGRVSLRIFRSLKPVIAAVNGAAVGVGVTMQLPMDIRLASTDAKFGFVFARRGITPEAASSWFLS
RVVGISTALEWCYTGRVFSAQEALERGLVRSLHAPEDLLPAARAIAREIADNAAPVSVAISRQLIWRMAGASHPMEAHKL
DSRAIQSRGRSADVKEGVSAFLEKRPAAFPERVSQDMPDFFDWGGEPPFA

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=260, Percent_Identity=34.6153846153846, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI260274832, Length=266, Percent_Identity=29.3233082706767, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI45643119, Length=266, Percent_Identity=29.3233082706767, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI260275230, Length=266, Percent_Identity=29.3233082706767, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI31542718, Length=257, Percent_Identity=29.9610894941634, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI116235487, Length=216, Percent_Identity=28.2407407407407, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI68989263, Length=234, Percent_Identity=26.0683760683761, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI70995211, Length=226, Percent_Identity=31.4159292035398, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI4757966, Length=287, Percent_Identity=24.7386759581882, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI51538581, Length=287, Percent_Identity=24.7386759581882, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI25453481, Length=195, Percent_Identity=28.2051282051282, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI51538573, Length=195, Percent_Identity=28.2051282051282, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI221136756, Length=251, Percent_Identity=25.0996015936255, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI221136753, Length=251, Percent_Identity=25.0996015936255, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI221307494, Length=214, Percent_Identity=28.0373831775701, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4757968, Length=203, Percent_Identity=27.0935960591133, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI49355787, Length=203, Percent_Identity=27.0935960591133, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI20127408, Length=188, Percent_Identity=27.1276595744681, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4502327, Length=263, Percent_Identity=27.7566539923954, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787660, Length=277, Percent_Identity=34.2960288808664, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787659, Length=270, Percent_Identity=30, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI221142681, Length=263, Percent_Identity=30.7984790874525, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788597, Length=274, Percent_Identity=27.7372262773723, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082183, Length=271, Percent_Identity=24.7232472324723, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790281, Length=219, Percent_Identity=27.3972602739726, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788682, Length=226, Percent_Identity=27.4336283185841, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17554946, Length=253, Percent_Identity=33.596837944664, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI25145438, Length=254, Percent_Identity=32.6771653543307, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17549921, Length=218, Percent_Identity=33.9449541284404, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17535521, Length=274, Percent_Identity=27.007299270073, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17540714, Length=225, Percent_Identity=29.7777777777778, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17560910, Length=256, Percent_Identity=28.125, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17536985, Length=217, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17540306, Length=246, Percent_Identity=27.2357723577236, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=210, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25141363, Length=188, Percent_Identity=25, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=194, Percent_Identity=29.3814432989691, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI20129971, Length=252, Percent_Identity=33.7301587301587, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24653477, Length=252, Percent_Identity=33.7301587301587, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24653139, Length=265, Percent_Identity=31.3207547169811, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI19920382, Length=218, Percent_Identity=33.9449541284404, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI21357171, Length=179, Percent_Identity=28.4916201117318, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654903, Length=176, Percent_Identity=28.4090909090909, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650670, Length=193, Percent_Identity=29.5336787564767, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 31247; Mature: 31115

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSNPTFETLCYAVEDGVATITLHRPDQLNAFTGQMMQDLIAAFDATDADDNVRAVIVT
CCCCCCCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
GSGRAFCAGADLSAGGATFDFEKRYGAKPETAHRDGGGRVSLRIFRSLKPVIAAVNGAAV
CCCCEEEECCCCCCCCCCEEHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCEE
GVGVTMQLPMDIRLASTDAKFGFVFARRGITPEAASSWFLSRVVGISTALEWCYTGRVFS
EEEEEEECCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEH
AQEALERGLVRSLHAPEDLLPAARAIAREIADNAAPVSVAISRQLIWRMAGASHPMEAHK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
LDSRAIQSRGRSADVKEGVSAFLEKRPAAFPERVSQDMPDFFDWGGEPPFA
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHCCCCCCCC
>Mature Secondary Structure 
TPSNPTFETLCYAVEDGVATITLHRPDQLNAFTGQMMQDLIAAFDATDADDNVRAVIVT
CCCCCCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
GSGRAFCAGADLSAGGATFDFEKRYGAKPETAHRDGGGRVSLRIFRSLKPVIAAVNGAAV
CCCCEEEECCCCCCCCCCEEHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCEE
GVGVTMQLPMDIRLASTDAKFGFVFARRGITPEAASSWFLSRVVGISTALEWCYTGRVFS
EEEEEEECCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEH
AQEALERGLVRSLHAPEDLLPAARAIAREIADNAAPVSVAISRQLIWRMAGASHPMEAHK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
LDSRAIQSRGRSADVKEGVSAFLEKRPAAFPERVSQDMPDFFDWGGEPPFA
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA