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The map label for this gene is mmgC [H]

Identifier: 73537350

GI number: 73537350

Start: 56274

End: 57554

Strand: Reverse

Name: mmgC [H]

Synonym: Reut_B3515

Alternate gene names: 73537350

Gene position: 57554-56274 (Counterclockwise)

Preceding gene: 73537351

Following gene: 73537349

Centisome position: 2.11

GC content: 64.87

Gene sequence:

>1281_bases
ATGGATTTCCAGCTTCCCGCAGAACTCGTCGCCTACCTGGAGGAACTCGACCGCTTCATCGAAGCCGAGATTGCCCCACT
GCAAGCCGAAAATGACAACCAGCGCTTCTTCGACCACCGCCGCGAGTGGGCGCGCACGGACTTCGACAACCAGGGCCTGC
CGCGTCCCGAATGGGAAGCGCTACTCGCCGAAGCGCGCCGCCGCGCCGATCGCGCTGGGCACCTGCGCTTCGCGCTGCCG
CCGGAGTACGGCGGCAAGGGAGGCGGCAACCTGTGGATGGCCGTGATCCGCGAACATCTGGCAGCAAAGGGACTGGGCCT
GCATAACGACCTGCAGAACGAGCATTCGATCGTCGGCAACAAGCCGTTCGTGCTGGTCATGCGCGACTACGGCACCGATG
CGCAGAAGGCGTTCTTTATCCCCGGCATGCTCGATGAAACCGTCAAGCTCGCGTTCGGCCTGACCGAGCCCGAACACGGC
TCCGATGCCACGCACATGGCAACGCGTGCCATTCCCGAGAAGCGCGATGGCAAGGAAGGCTGGCGCATCGATGGCGAGAA
GATGTGGACCACGGGCATGCACACCGCCACGCATTGCGTGGTTTTCGCGCGCACCAGCGGCGAGGACGGCGACGCACGCG
GCATCACGGCTTTCCTCGTGCCGTCGGACACCGCGGGCGTACGCGTGGAAGAGTACCTGTGGACCTTCAACATGCCGACG
GACCACCCGCGCGTGAGCTTCACCGGCGTGTGGGTGCCAGCCGACGCAGTGCTCGCCAAGGCCGGTTCGGGGCTATCCGT
GGCCCAGCATTTCGTGCACGAGAACCGCATCCGGCAAGCGGCCGCGAGCCTCGGCGCGGCCGAGTACTGCATCCGCGAAA
GCGTGCGCTATGCGCGCGAGCGCAAGCCGTTCGGGCAGGAACTCGCGCGCAACCAGGGCATACAGTTCCCGTTGGTCGAG
CTGGCCACGCGTGCGCAGATGCTGCGTGCGTTTATCCGCCAGACCGCATGGGAGATGGACCGCATCCCGAAGAAGGAGGT
GGAGAAGCAGCTCTCGGACAAGGTCTCGATGTGCAACTACACCGCCAACCGCCTGTGCTGCGAGGCTGCCGACCTGGCCA
TGCAGGTGCACGGCGGCATTGGCTATTCGCGCCACAAGCCGTTCGAGCACATCTACCGTCACCACCGCCGCTACCGCATT
ACCGAAGGCTCGGACGAGATCCAGATGCGCAAGGTGGCGGCTTACCTGTTCGGCTATATCAGCCGCGAATCGAAAGCCTG
A

Upstream 100 bases:

>100_bases
CCTCGCCGCGCATCTGTGGACCACTACCCTGAACAAGCTCGCCATCGACCAGCCTGCGTACAGCAGCTATCGCGCGGCGT
TGCAAGCCATGGAGCAATGA

Downstream 100 bases:

>100_bases
ACGAAGGGACGGAGACCTAGATGAACGTGGACCATTTGGCCACACTGCCGCGCGCCGTGCAGCATCTGGCGCGCGTGCAG
AAGACGCAGATCGCCTATGT

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MDFQLPAELVAYLEELDRFIEAEIAPLQAENDNQRFFDHRREWARTDFDNQGLPRPEWEALLAEARRRADRAGHLRFALP
PEYGGKGGGNLWMAVIREHLAAKGLGLHNDLQNEHSIVGNKPFVLVMRDYGTDAQKAFFIPGMLDETVKLAFGLTEPEHG
SDATHMATRAIPEKRDGKEGWRIDGEKMWTTGMHTATHCVVFARTSGEDGDARGITAFLVPSDTAGVRVEEYLWTFNMPT
DHPRVSFTGVWVPADAVLAKAGSGLSVAQHFVHENRIRQAAASLGAAEYCIRESVRYARERKPFGQELARNQGIQFPLVE
LATRAQMLRAFIRQTAWEMDRIPKKEVEKQLSDKVSMCNYTANRLCCEAADLAMQVHGGIGYSRHKPFEHIYRHHRRYRI
TEGSDEIQMRKVAAYLFGYISRESKA

Sequences:

>Translated_426_residues
MDFQLPAELVAYLEELDRFIEAEIAPLQAENDNQRFFDHRREWARTDFDNQGLPRPEWEALLAEARRRADRAGHLRFALP
PEYGGKGGGNLWMAVIREHLAAKGLGLHNDLQNEHSIVGNKPFVLVMRDYGTDAQKAFFIPGMLDETVKLAFGLTEPEHG
SDATHMATRAIPEKRDGKEGWRIDGEKMWTTGMHTATHCVVFARTSGEDGDARGITAFLVPSDTAGVRVEEYLWTFNMPT
DHPRVSFTGVWVPADAVLAKAGSGLSVAQHFVHENRIRQAAASLGAAEYCIRESVRYARERKPFGQELARNQGIQFPLVE
LATRAQMLRAFIRQTAWEMDRIPKKEVEKQLSDKVSMCNYTANRLCCEAADLAMQVHGGIGYSRHKPFEHIYRHHRRYRI
TEGSDEIQMRKVAAYLFGYISRESKA
>Mature_426_residues
MDFQLPAELVAYLEELDRFIEAEIAPLQAENDNQRFFDHRREWARTDFDNQGLPRPEWEALLAEARRRADRAGHLRFALP
PEYGGKGGGNLWMAVIREHLAAKGLGLHNDLQNEHSIVGNKPFVLVMRDYGTDAQKAFFIPGMLDETVKLAFGLTEPEHG
SDATHMATRAIPEKRDGKEGWRIDGEKMWTTGMHTATHCVVFARTSGEDGDARGITAFLVPSDTAGVRVEEYLWTFNMPT
DHPRVSFTGVWVPADAVLAKAGSGLSVAQHFVHENRIRQAAASLGAAEYCIRESVRYARERKPFGQELARNQGIQFPLVE
LATRAQMLRAFIRQTAWEMDRIPKKEVEKQLSDKVSMCNYTANRLCCEAADLAMQVHGGIGYSRHKPFEHIYRHHRRYRI
TEGSDEIQMRKVAAYLFGYISRESKA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI187960098, Length=351, Percent_Identity=30.7692307692308, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI4557231, Length=351, Percent_Identity=30.7692307692308, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI4501859, Length=350, Percent_Identity=28.5714285714286, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI4557233, Length=419, Percent_Identity=26.7303102625298, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI21361497, Length=352, Percent_Identity=28.4090909090909, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI76496475, Length=402, Percent_Identity=27.6119402985075, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4557235, Length=402, Percent_Identity=27.6119402985075, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI7656849, Length=413, Percent_Identity=27.1186440677966, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI4501857, Length=387, Percent_Identity=26.0981912144703, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI226958412, Length=399, Percent_Identity=25.062656641604, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI38505218, Length=297, Percent_Identity=25.5892255892256, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI226958414, Length=346, Percent_Identity=26.0115606936416, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI48976061, Length=290, Percent_Identity=25.5172413793103, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI7669494, Length=282, Percent_Identity=29.4326241134752, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI211971008, Length=290, Percent_Identity=25.5172413793103, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4503943, Length=267, Percent_Identity=30.3370786516854, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI87081958, Length=260, Percent_Identity=28.0769230769231, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786223, Length=258, Percent_Identity=27.906976744186, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17570075, Length=427, Percent_Identity=27.1662763466042, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17534899, Length=364, Percent_Identity=30.2197802197802, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17569725, Length=365, Percent_Identity=29.3150684931507, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71985184, Length=340, Percent_Identity=31.1764705882353, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17506239, Length=399, Percent_Identity=25.5639097744361, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17508101, Length=345, Percent_Identity=27.536231884058, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17533517, Length=371, Percent_Identity=26.9541778975741, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71985192, Length=301, Percent_Identity=29.2358803986711, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17505929, Length=342, Percent_Identity=27.7777777777778, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17551932, Length=337, Percent_Identity=25.8160237388724, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=409, Percent_Identity=25.4278728606357, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71990804, Length=267, Percent_Identity=26.9662921348315, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32563615, Length=243, Percent_Identity=30.4526748971193, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562446, Length=295, Percent_Identity=25.7627118644068, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17534353, Length=273, Percent_Identity=27.1062271062271, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=293, Percent_Identity=24.9146757679181, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24660351, Length=352, Percent_Identity=30.1136363636364, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24646207, Length=404, Percent_Identity=28.960396039604, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24666513, Length=355, Percent_Identity=29.8591549295775, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281363737, Length=392, Percent_Identity=28.0612244897959, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21356377, Length=401, Percent_Identity=26.4339152119701, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21355753, Length=395, Percent_Identity=26.5822784810127, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19920834, Length=277, Percent_Identity=32.4909747292419, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 48327; Mature: 48327

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFQLPAELVAYLEELDRFIEAEIAPLQAENDNQRFFDHRREWARTDFDNQGLPRPEWEA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHH
LLAEARRRADRAGHLRFALPPEYGGKGGGNLWMAVIREHLAAKGLGLHNDLQNEHSIVGN
HHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCHHCCCCC
KPFVLVMRDYGTDAQKAFFIPGMLDETVKLAFGLTEPEHGSDATHMATRAIPEKRDGKEG
CCEEEEEECCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCC
WRIDGEKMWTTGMHTATHCVVFARTSGEDGDARGITAFLVPSDTAGVRVEEYLWTFNMPT
CEECCCCEEECCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCCEEEHEEEEECCCC
DHPRVSFTGVWVPADAVLAKAGSGLSVAQHFVHENRIRQAAASLGAAEYCIRESVRYARE
CCCCEEEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKPFGQELARNQGIQFPLVELATRAQMLRAFIRQTAWEMDRIPKKEVEKQLSDKVSMCNY
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TANRLCCEAADLAMQVHGGIGYSRHKPFEHIYRHHRRYRITEGSDEIQMRKVAAYLFGYI
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHHH
SRESKA
HHCCCC
>Mature Secondary Structure
MDFQLPAELVAYLEELDRFIEAEIAPLQAENDNQRFFDHRREWARTDFDNQGLPRPEWEA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHH
LLAEARRRADRAGHLRFALPPEYGGKGGGNLWMAVIREHLAAKGLGLHNDLQNEHSIVGN
HHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCHHCCCCC
KPFVLVMRDYGTDAQKAFFIPGMLDETVKLAFGLTEPEHGSDATHMATRAIPEKRDGKEG
CCEEEEEECCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCC
WRIDGEKMWTTGMHTATHCVVFARTSGEDGDARGITAFLVPSDTAGVRVEEYLWTFNMPT
CEECCCCEEECCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCCEEEHEEEEECCCC
DHPRVSFTGVWVPADAVLAKAGSGLSVAQHFVHENRIRQAAASLGAAEYCIRESVRYARE
CCCCEEEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKPFGQELARNQGIQFPLVELATRAQMLRAFIRQTAWEMDRIPKKEVEKQLSDKVSMCNY
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TANRLCCEAADLAMQVHGGIGYSRHKPFEHIYRHHRRYRITEGSDEIQMRKVAAYLFGYI
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHHH
SRESKA
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]