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The map label for this gene is thcR [H]

Identifier: 73537306

GI number: 73537306

Start: 9260

End: 10366

Strand: Reverse

Name: thcR [H]

Synonym: Reut_B3471

Alternate gene names: 73537306

Gene position: 10366-9260 (Counterclockwise)

Preceding gene: 73537307

Following gene: 73537305

Centisome position: 0.38

GC content: 62.33

Gene sequence:

>1107_bases
ATGCGGCGATCATCCTCGCAGGCTCCAACGATACAGACAGCCCTCGAACATTCCGACGCAATGCCGCCCCGTCAAAGTAT
CGAACAAGACGCGTTTCCGGATCTGCTCGCCCACTATCCCTTGTTTCGCTCCAAGGATGTCGAGGAAACGCAGGGCAAGG
TTGCGGCGGTGTTTTGCCCGCACGTGCTTCGCGTCGTTGGTGCGACGCAGCATCTGCGCGTCCAGCACAACCTGGTAAAG
CTGCATGACACCGCTATCAATTTCCTGTCGTACGGTGCGGACGTAGACATCGACCCGGGCCGGCTGGGCAACTTTTACCT
GGCGCAGATTCCTGTCGCAGGCCATGCAGACATCCAGTGTGGCGCGCAAAGTCTGGTGTCTGACGTCAGGACAGCCAGTT
TGCTCAGCCCGGACACGCCCACGCGAATGCACTGGCACCAGGACTGCGCGCAAGTGTTGCTCTGGATAGAGAAGGCGGCA
ATGGAGCACCGCTTCGCCTTGTTGACAGGGCGCGACCCCGTGGGCTCGCTCGCCTTCGATCCGTCGCTGCCCCAGCACGC
AGGTCTTGCCAGCCCCTGGACGCAGGCTGTGCTCGACCTCGCACGGAATATCGATCAGCACGGCACGCACTGGCTCGCGT
TTCCCGCAGCGGTGGCTTCGATGGAAGACTATCTCTTGCGGACACTGCTGCTGCTTCAGCCGCACACCTACACCTATCTC
CTCGCGCGCAGCGCCGAACCGGCCAGGCCGCGTCATATGCAGCGGGTCATCGACTACGTCCACGCGAATGCGGAAACGCC
CCTGACGGTGGCAGATCTGGCGCAGATCGCGTGCGTCAGTGTCCGGGCACTGGAGGAAGGCTTCCGACGTCATCTCAATA
CCACGCCGGTTGGATATCTGCGCGACGTCAGGCTGGACGGGGTGCGACAAGCACTGATCGCCGCAGCGGGAGCCGAGCAC
GCCTCCATCACGGATATCGCATATCGGTTTGGCTTTACGCATCTGGGCCGCTTTGCGGCCTATTACAAGCAGCGCTTCGG
CGTTTCTCCCTCGGCGACTTTGCGTGGCGAGGCGACGGAACGCCCTTCCGGCGATACGCGGCGTTGA

Upstream 100 bases:

>100_bases
ATGTCGTATCTTTCCCGTGATCCCATTCCCTCCGTCAGCCCGGCCACAAATATGATTTTGGAATTATTTAGTCTTAAATT
ATGATTGTCCTAAGCCCGGA

Downstream 100 bases:

>100_bases
GAGGCATCGGTCTGCGTCGTTGATACGACAATAGGGCGGCGCACGCCGCACACTAGCACCGGCGGGCGAGCTGTCTGCCA
GGTGGCCCTCTTCTTTCTGC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MRRSSSQAPTIQTALEHSDAMPPRQSIEQDAFPDLLAHYPLFRSKDVEETQGKVAAVFCPHVLRVVGATQHLRVQHNLVK
LHDTAINFLSYGADVDIDPGRLGNFYLAQIPVAGHADIQCGAQSLVSDVRTASLLSPDTPTRMHWHQDCAQVLLWIEKAA
MEHRFALLTGRDPVGSLAFDPSLPQHAGLASPWTQAVLDLARNIDQHGTHWLAFPAAVASMEDYLLRTLLLLQPHTYTYL
LARSAEPARPRHMQRVIDYVHANAETPLTVADLAQIACVSVRALEEGFRRHLNTTPVGYLRDVRLDGVRQALIAAAGAEH
ASITDIAYRFGFTHLGRFAAYYKQRFGVSPSATLRGEATERPSGDTRR

Sequences:

>Translated_368_residues
MRRSSSQAPTIQTALEHSDAMPPRQSIEQDAFPDLLAHYPLFRSKDVEETQGKVAAVFCPHVLRVVGATQHLRVQHNLVK
LHDTAINFLSYGADVDIDPGRLGNFYLAQIPVAGHADIQCGAQSLVSDVRTASLLSPDTPTRMHWHQDCAQVLLWIEKAA
MEHRFALLTGRDPVGSLAFDPSLPQHAGLASPWTQAVLDLARNIDQHGTHWLAFPAAVASMEDYLLRTLLLLQPHTYTYL
LARSAEPARPRHMQRVIDYVHANAETPLTVADLAQIACVSVRALEEGFRRHLNTTPVGYLRDVRLDGVRQALIAAAGAEH
ASITDIAYRFGFTHLGRFAAYYKQRFGVSPSATLRGEATERPSGDTRR
>Mature_368_residues
MRRSSSQAPTIQTALEHSDAMPPRQSIEQDAFPDLLAHYPLFRSKDVEETQGKVAAVFCPHVLRVVGATQHLRVQHNLVK
LHDTAINFLSYGADVDIDPGRLGNFYLAQIPVAGHADIQCGAQSLVSDVRTASLLSPDTPTRMHWHQDCAQVLLWIEKAA
MEHRFALLTGRDPVGSLAFDPSLPQHAGLASPWTQAVLDLARNIDQHGTHWLAFPAAVASMEDYLLRTLLLLQPHTYTYL
LARSAEPARPRHMQRVIDYVHANAETPLTVADLAQIACVSVRALEEGFRRHLNTTPVGYLRDVRLDGVRQALIAAAGAEH
ASITDIAYRFGFTHLGRFAAYYKQRFGVSPSATLRGEATERPSGDTRR

Specific function: Probably involved in the positive regulation of the thc operon for the degradation of the thiocarbamate herbicide EPTC [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788778, Length=104, Percent_Identity=38.4615384615385, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 40738; Mature: 40738

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSSSQAPTIQTALEHSDAMPPRQSIEQDAFPDLLAHYPLFRSKDVEETQGKVAAVFCP
CCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEHHHH
HVLRVVGATQHLRVQHNLVKLHDTAINFLSYGADVDIDPGRLGNFYLAQIPVAGHADIQC
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCHHH
GAQSLVSDVRTASLLSPDTPTRMHWHQDCAQVLLWIEKAAMEHRFALLTGRDPVGSLAFD
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCC
PSLPQHAGLASPWTQAVLDLARNIDQHGTHWLAFPAAVASMEDYLLRTLLLLQPHTYTYL
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LARSAEPARPRHMQRVIDYVHANAETPLTVADLAQIACVSVRALEEGFRRHLNTTPVGYL
EECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
RDVRLDGVRQALIAAAGAEHASITDIAYRFGFTHLGRFAAYYKQRFGVSPSATLRGEATE
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
RPSGDTRR
CCCCCCCC
>Mature Secondary Structure
MRRSSSQAPTIQTALEHSDAMPPRQSIEQDAFPDLLAHYPLFRSKDVEETQGKVAAVFCP
CCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEHHHH
HVLRVVGATQHLRVQHNLVKLHDTAINFLSYGADVDIDPGRLGNFYLAQIPVAGHADIQC
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCHHH
GAQSLVSDVRTASLLSPDTPTRMHWHQDCAQVLLWIEKAAMEHRFALLTGRDPVGSLAFD
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCC
PSLPQHAGLASPWTQAVLDLARNIDQHGTHWLAFPAAVASMEDYLLRTLLLLQPHTYTYL
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LARSAEPARPRHMQRVIDYVHANAETPLTVADLAQIACVSVRALEEGFRRHLNTTPVGYL
EECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
RDVRLDGVRQALIAAAGAEHASITDIAYRFGFTHLGRFAAYYKQRFGVSPSATLRGEATE
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
RPSGDTRR
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7836301 [H]