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The map label for this gene is exp5 [H]

Identifier: 71911505

GI number: 71911505

Start: 1651890

End: 1653785

Strand: Reverse

Name: exp5 [H]

Synonym: M5005_Spy_1692

Alternate gene names: 71911505

Gene position: 1653785-1651890 (Counterclockwise)

Preceding gene: 71911506

Following gene: 71911504

Centisome position: 89.95

GC content: 44.73

Gene sequence:

>1896_bases
TTGATCAATCGGATAACAGGTGCTTTTTATGGCGTGTCTAGTACTATGCTAGCTGATCCAGAAGCAAAAATCACAAGCCT
CCTTGGCACTCAAATGATCGTTAAAGATTATTTCACCAGTGTCTTGGAATCTCCAGCTTTAAACACAGGGGTTTTTGTTG
GGATTATTGCAGGGTTCGTAGGAGCAACGGCCTATAACAAATACTATAATTACCGTAAACTTCCTGAAGTTTTGACCTTC
TTTAATGGGAAGCGTTTTGTACCATTTGTCGTTATTTTACGTTCTATTTTTGTAGCCCTTATTTTGGTTGTTGTTTGGCC
GGTGATCCAGTCTGGGATTAACAGTTTTGGGATGTGGATTGCCTCTTCACAAGATTCAGCTCCAATCCTAGCCCCATTCC
TATATGGTACCTTGGAACGTCTCTTGTTGCCATTTGGTCTTCACCACATGTTGACGATCCCAATGAACTATACAGCTCTT
GGTGGAACTTATGAGGTCATGACAGGTGCAGCAGCGGGGACAAAAGTATTTGGTCAAGACCCTTTGTGGCTTGCTTGGGT
AACTGACCTTGTTCACCTTAAAGGATCAGACGCTTCAGCCTATAGTCACTTAATGGATAGTGTGACTCCAGCTCGTTTCA
AAGTAGGACAAATGATTGGAGCTACCGGAACATTGATGGGGGTTGCCTTAGCCATGTACCGTAATGTGGATGCCGATAAA
AAACACACATACAAAATGATGTTCATCTCAGCAGCGGCAGCGGTCTTTTTGACAGGGGTAACTGAGCCACTTGAGTACCT
ATTTATGTTTGCAGCAATGCCACTTTACATCGTCTATGCCCTTGTTCAAGGAGCTTCATTTGCCATGGCAGACCTTGTGA
ATCTCCGTGTTCACTCATTTGGAAATATAGAGCTACTAACCCGCACCCCTATGGCTCTTAAAGCAGGCCTAGGCATGGAT
GTGATTAACTTTGTTTGGGTTTCTGTCCTCTTTGCAGTTATCATGTACTTTATTGCAGATATGATGATCAAGAAAATGCA
TCTCGCAACAGCTGGCCGTTTAGGCAACTACGATGCCGATATACTGGGTGACCGTAACACTCAAACAAGACCTACCCAAG
TAGCAGATAGCAACTCTCAAGTCGTGCAAATCGTTAATCTCCTTGGTGGGGCAGGCAATATTGATGATGTTGATGCTTGT
ATGACGCGCTTACGAGTGACGGTCAAAGACCCCGCTAAGGTTGGTGCTGAGGACGATTGGAAAAAAGCTGGCGCTATAGG
CTTGATCCAAAAAGGCAACGGCGTTCAAGCGGTCTATGGCCCTAAAGCAGATATTTTGAAATCAGATATTCAAGATTTGC
TGGACTCAGGTGCTCTTATTCCAGAAGTCAATATGTCACAGCTCACTAGCAAACCGACTCCCGCAAAAGATTTTAAACAC
GTGACAGAAGATGTGCTATCAGTGGCAGACGGGATGGTTCTCCCAATCACAGGTGTAAAAGACCAGGTGTTTGCGGCTAA
GATGATGGGAGATGGGTTTGCGGTTGAACCAACCCATGGTAATATCTATGCACCCGTAGCTGGCCTTGTGACCAGTGTCT
TTCCGACCAAGCATGCCTTTGGTTTACTGACAGATAATGGTCTTGAAGTGCTGGTGCACGTGGGACTTGATACCGTCGCC
TTAAATGGTGTGCCTTTTTCAGTCAAAGTCTCAGAAGGGCAACGGGTTCATGCAGGTGACCTATTAGTCGTAGCAGATCT
TGCTGCTATTAAATCAGCAGAGCGTGAAACAATCATTGTTGTTGCTTTTACCAACACAACAGAGATCCAAGATGTGACCT
TGACATCTTTAGGAGCTCAGCCTGCTAAGACTAAAGTAGCTACCGTAGAACTTTAA

Upstream 100 bases:

>100_bases
CTGTTATTGTTAACCTTCACTTGCTATTTGCCTTGGCCATTGGTGGTAGTTGGGCTAAAGAAAGAGCTGGAGGGGCCTTT
GCCTCAGGCTTGCTTTTGTC

Downstream 100 bases:

>100_bases
CAAAACATCACGAGATAGTGATAGGTAATAGCCATAGCTGGTTTAGGCCCTATGGCTCTTCTTGTCTTATAAAGGAGGAT
TAATGACCAAGGTATTAACA

Product: PTS system, glucose-specific IIABC component

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MINRITGAFYGVSSTMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGATAYNKYYNYRKLPEVLTF
FNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIASSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTAL
GGTYEVMTGAAAGTKVFGQDPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVDADK
KHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSFGNIELLTRTPMALKAGLGMD
VINFVWVSVLFAVIMYFIADMMIKKMHLATAGRLGNYDADILGDRNTQTRPTQVADSNSQVVQIVNLLGGAGNIDDVDAC
MTRLRVTVKDPAKVGAEDDWKKAGAIGLIQKGNGVQAVYGPKADILKSDIQDLLDSGALIPEVNMSQLTSKPTPAKDFKH
VTEDVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTHGNIYAPVAGLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVA
LNGVPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETIIVVAFTNTTEIQDVTLTSLGAQPAKTKVATVEL

Sequences:

>Translated_631_residues
MINRITGAFYGVSSTMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGATAYNKYYNYRKLPEVLTF
FNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIASSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTAL
GGTYEVMTGAAAGTKVFGQDPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVDADK
KHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSFGNIELLTRTPMALKAGLGMD
VINFVWVSVLFAVIMYFIADMMIKKMHLATAGRLGNYDADILGDRNTQTRPTQVADSNSQVVQIVNLLGGAGNIDDVDAC
MTRLRVTVKDPAKVGAEDDWKKAGAIGLIQKGNGVQAVYGPKADILKSDIQDLLDSGALIPEVNMSQLTSKPTPAKDFKH
VTEDVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTHGNIYAPVAGLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVA
LNGVPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETIIVVAFTNTTEIQDVTLTSLGAQPAKTKVATVEL
>Mature_631_residues
MINRITGAFYGVSSTMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGATAYNKYYNYRKLPEVLTF
FNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIASSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTAL
GGTYEVMTGAAAGTKVFGQDPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVDADK
KHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSFGNIELLTRTPMALKAGLGMD
VINFVWVSVLFAVIMYFIADMMIKKMHLATAGRLGNYDADILGDRNTQTRPTQVADSNSQVVQIVNLLGGAGNIDDVDAC
MTRLRVTVKDPAKVGAEDDWKKAGAIGLIQKGNGVQAVYGPKADILKSDIQDLLDSGALIPEVNMSQLTSKPTPAKDFKH
VTEDVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTHGNIYAPVAGLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVA
LNGVPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETIIVVAFTNTTEIQDVTLTSLGAQPAKTKVATVEL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786894, Length=590, Percent_Identity=33.2203389830508, Blast_Score=241, Evalue=7e-65,
Organism=Escherichia coli, GI1787343, Length=412, Percent_Identity=33.0097087378641, Blast_Score=198, Evalue=1e-51,
Organism=Escherichia coli, GI1787908, Length=419, Percent_Identity=31.980906921241, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1790159, Length=128, Percent_Identity=39.0625, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788757, Length=149, Percent_Identity=35.5704697986577, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011300 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 67800; Mature: 67800

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINRITGAFYGVSSTMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFV
CCCCCCCHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
GATAYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWI
HHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCEEE
ASSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQD
ECCCCCCCHHHHHHHHHHHHHHHHHCCHHEEEECCCEEECCCCHHHHCCCCCCCCCCCCC
PLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVDADK
CCHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC
KHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSF
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
GNIELLTRTPMALKAGLGMDVINFVWVSVLFAVIMYFIADMMIKKMHLATAGRLGNYDAD
CCEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
ILGDRNTQTRPTQVADSNSQVVQIVNLLGGAGNIDDVDACMTRLRVTVKDPAKVGAEDDW
HCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHEEEECCHHHCCCCCCH
KKAGAIGLIQKGNGVQAVYGPKADILKSDIQDLLDSGALIPEVNMSQLTSKPTPAKDFKH
HHCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHH
VTEDVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTHGNIYAPVAGLVTSVFPTKHAF
HHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCEEECCCCCCEECCHHHHHHHHCCCHHHE
GLLTDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETIIV
EEEECCCCEEEEEECCCEEEECCCCEEEEECCCCEEECCCEEEEHHHHHHHCCCCCEEEE
VAFTNTTEIQDVTLTSLGAQPAKTKVATVEL
EEECCCCCCCEEEHHHCCCCCCCCEEEEEEC
>Mature Secondary Structure
MINRITGAFYGVSSTMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFV
CCCCCCCHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
GATAYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWI
HHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCEEE
ASSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQD
ECCCCCCCHHHHHHHHHHHHHHHHHCCHHEEEECCCEEECCCCHHHHCCCCCCCCCCCCC
PLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVDADK
CCHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC
KHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSF
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
GNIELLTRTPMALKAGLGMDVINFVWVSVLFAVIMYFIADMMIKKMHLATAGRLGNYDAD
CCEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
ILGDRNTQTRPTQVADSNSQVVQIVNLLGGAGNIDDVDACMTRLRVTVKDPAKVGAEDDW
HCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHEEEECCHHHCCCCCCH
KKAGAIGLIQKGNGVQAVYGPKADILKSDIQDLLDSGALIPEVNMSQLTSKPTPAKDFKH
HHCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHH
VTEDVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTHGNIYAPVAGLVTSVFPTKHAF
HHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCEEECCCCCCEECCHHHHHHHHCCCHHHE
GLLTDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETIIV
EEEECCCCEEEEEECCCEEEECCCCEEEEECCCCEEECCCEEEEHHHHHHHCCCCCEEEE
VAFTNTTEIQDVTLTSLGAQPAKTKVATVEL
EEECCCCCCCEEEHHHCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11463916; 7934910 [H]