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The map label for this gene is salA [H]

Identifier: 71911444

GI number: 71911444

Start: 1595432

End: 1595578

Strand: Reverse

Name: salA [H]

Synonym: M5005_Spy_1631

Alternate gene names: 71911444

Gene position: 1595578-1595432 (Counterclockwise)

Preceding gene: 229558514

Following gene: 71911443

Centisome position: 86.78

GC content: 34.01

Gene sequence:

>147_bases
ATGAAAAATTCAAAGGATATTTTGACTAATGCTATCGAAGAAGTTTCTGAAAAAGAACTTATGGAAGTAGCTGGTGGTAA
AAAAGGTTCCGGTTGGTTTGCAACTATTACTGATGACTGTCCGAACTCAGTATTTGTTTGTTGTTAA

Upstream 100 bases:

>100_bases
CATTTTTGCACTTTTTACTCATTGAAAATGAAGACGTATTATTTACAATAAAAGTGTAGAAAATAGTCACTACATACTGA
TAGAAAGGAGAATGAGTTTT

Downstream 100 bases:

>100_bases
TTAAAACAATCTGGACAAGCAGACTAAAAATTTCCTGTTTAGACTCAGTCTAGGCAGGATTTTTAAGTAGTGGTAGGAAA
AAATGATAAAAAGAAATGAA

Product: lantibiotic salivaricin A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 48; Mature: 48

Protein sequence:

>48_residues
MKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCPNSVFVCC

Sequences:

>Translated_48_residues
MKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCPNSVFVCC
>Mature_48_residues
MKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCPNSVFVCC

Specific function: Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembran

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type A lantibiotic family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007682 [H]

Pfam domain/function: PF04604 L_biotic_typeA [H]

EC number: NA

Molecular weight: Translated: 5197; Mature: 5197

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
10.4 %Cys+Met (Translated Protein)
6.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
10.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCPNSVFVCC
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEC
>Mature Secondary Structure
MKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCPNSVFVCC
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8357242 [H]