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The map label for this gene is adcA [H]

Identifier: 71910356

GI number: 71910356

Start: 533063

End: 534610

Strand: Direct

Name: adcA [H]

Synonym: M5005_Spy_0543

Alternate gene names: 71910356

Gene position: 533063-534610 (Clockwise)

Preceding gene: 71910355

Following gene: 71910357

Centisome position: 28.99

GC content: 38.82

Gene sequence:

>1548_bases
ATGAAAAAGAAAATTCTTTTAATGATGAGTTTAATCAGTGTCTTTTTTGCTTGGCAACTTACTCAGGCAAAACAAGTCTT
AGCAGAGGGTAAAGTGAAGGTGGTGACAACTTTCTATCCTGTTTATGAATTTACAAAAGGGGTTATTGGTAATGATGGCG
ATGTTTTCATGCTTATGAAAGCAGGAACGGAACCTCATGATTTTGAGCCTTCTACAAAAGACATTAAAAAAATCCAAGAT
GCAGATGCATTTGTTTATATGGATGACAATATGGAAACTTGGGTTTCTGATGTGAAAAAATCATTGACATCTAAAAAAGT
GACCATCGTCAAGGGAACTGGTAACATGCTCTTGGTAGCAGGAGCTGGACATGACCATCACCATGAGGATGCTGACAAAA
AGCATGAGCATAATAAACATAGCGAAGAAGGACACAACCATGCTTTTGACCCACACGTGTGGTTGTCACCATACCGTAGC
ATTACAGTCGTTGAAAATATTCGCGACAGTCTTTCAAAAGCTTACCCAGAAAAAGCAGAGAACTTCAAAGCCAATGCCGC
TACTTATATTGAAAAATTAAAAGAGCTTGACAAAGACTATACGGCAGCACTTTCAGATGCTAAGCAAAAGAGCTTTGTGA
CACAACACGCAGCTTTTGGTTATATGGCACTTGACTATGGCTTGAACCAAATTTCTATTAATGGTGTCACACCAGATGCA
GAACCATCAGCAAAACGTATTGCTACTTTGTCAAAATACGTTAAAAAATATGGCATCAAATACATTTATTTTGAGGAAAA
TGCGTCAAGTAAAGTCGCAAAAACCCTAGCTAAAGAAGCAGGAGTTAAAGCGGCTGTGCTTAGTCCGCTTGAAGGTTTGA
CTGAAAAAGAGATGAAAGCTGGCCAAGATTACTTTACGGTCATGCGTAAAAACCTTGAAACCTTACGCTTAACCACTGAT
GTGGCTGGTAAAGAAATTCTTCCAGAAAAAGACACGACTAAGACAGTTTACAATGGTTATTTCAAAGACAAAGAAGTCAA
AGATCGTCAATTATCTGACTGGTCAGGTAGCTGGCAATCTGTTTACCCCTATCTACAAAATGGTACTTTAGACCAAGTTT
GGGACTACAAGGCTAAAAAATCTAAAGGTAAAATGACAGCAGCCGAGTACAAAGATTACTACACTACTGGTTATAAAACT
GACGTGGAACAAATCAAAATCAATGGTAAGAAAAAGACCATGACCTTTGTTCGTAATGGTGAAAAGAAAACCTTCACTTA
CACATACGCCGGCAAAGAAATCTTGACCTATCCAAAAGGAAATCGCGGGGTTCGTTTCATGTTTGAAGCTAAAGAAGCAG
ATGCTGGCGAATTCAAATACGTTCAATTCAGTGACCATGCCATTGCTCCTGAAAAAGCAAAGCATTTCCACCTGTACTGG
GGTGGTGACAGCCAAGAAAAATTACATAAAGAGTTAGAACATTGGCCAACTTACTACGGTTCAGACTTATCTGGTCGTGA
AATCGCCCAAGAAATCAATGCTCATTAA

Upstream 100 bases:

>100_bases
AGGAAAAGTAATCGCAAAAAGACAAAAACTTGGAAAAAAAATCAAAGTATGCTATACTTAACTGGTCAATTTTTAACCAG
TTAATAACAAAGGAGGAATC

Downstream 100 bases:

>100_bases
TCTTAACTCACTAAGCAAATCTTCTTTTAAGGAGGTTTGCTTTTTCTTTGTGGAGTAAAAAAATTTAATAATTCTCAACA
TTAATTTGACGGACACTTAT

Product: high-affinity zinc uptake system protein znuA precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEFTKGVIGNDGDVFMLMKAGTEPHDFEPSTKDIKKIQD
ADAFVYMDDNMETWVSDVKKSLTSKKVTIVKGTGNMLLVAGAGHDHHHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRS
ITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAAFGYMALDYGLNQISINGVTPDA
EPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTLAKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTD
VAGKEILPEKDTTKTVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQNGTLDQVWDYKAKKSKGKMTAAEYKDYYTTGYKT
DVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEAKEADAGEFKYVQFSDHAIAPEKAKHFHLYW
GGDSQEKLHKELEHWPTYYGSDLSGREIAQEINAH

Sequences:

>Translated_515_residues
MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEFTKGVIGNDGDVFMLMKAGTEPHDFEPSTKDIKKIQD
ADAFVYMDDNMETWVSDVKKSLTSKKVTIVKGTGNMLLVAGAGHDHHHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRS
ITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAAFGYMALDYGLNQISINGVTPDA
EPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTLAKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTD
VAGKEILPEKDTTKTVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQNGTLDQVWDYKAKKSKGKMTAAEYKDYYTTGYKT
DVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEAKEADAGEFKYVQFSDHAIAPEKAKHFHLYW
GGDSQEKLHKELEHWPTYYGSDLSGREIAQEINAH
>Mature_515_residues
MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEFTKGVIGNDGDVFMLMKAGTEPHDFEPSTKDIKKIQD
ADAFVYMDDNMETWVSDVKKSLTSKKVTIVKGTGNMLLVAGAGHDHHHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRS
ITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAAFGYMALDYGLNQISINGVTPDA
EPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTLAKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTD
VAGKEILPEKDTTKTVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQNGTLDQVWDYKAKKSKGKMTAAEYKDYYTTGYKT
DVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEAKEADAGEFKYVQFSDHAIAPEKAKHFHLYW
GGDSQEKLHKELEHWPTYYGSDLSGREIAQEINAH

Specific function: Part of the ATP-driven transport system AdcABC for zinc [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI1788284, Length=188, Percent_Identity=48.4042553191489, Blast_Score=182, Evalue=6e-47,
Organism=Escherichia coli, GI87081990, Length=261, Percent_Identity=24.904214559387, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR006128
- InterPro:   IPR015304 [H]

Pfam domain/function: PF01297 SBP_bac_9; PF09223 YodA [H]

EC number: NA

Molecular weight: Translated: 58560; Mature: 58560

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEFTKGVIGNDGDVFMLMK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHCCCCCCCCCEEEEEE
AGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVSDVKKSLTSKKVTIVKGTGNMLLVA
CCCCCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEE
GAGHDHHHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRSITVVENIRDSLSKAYPEKAE
ECCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHCCHHHH
NFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAAFGYMALDYGLNQISINGVTPDA
CCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEECCCCCCC
EPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTLAKEAGVKAAVLSPLEGLTEKEMKA
CCHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHC
GQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTKTVYNGYFKDKEVKDRQLSDWSGSWQS
CHHHHHHHHHCHHHEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHH
VYPYLQNGTLDQVWDYKAKKSKGKMTAAEYKDYYTTGYKTDVEQIKINGKKKTMTFVRNG
HHHHHCCCCHHHHHCCHHHHCCCCEEHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEECC
EKKTFTYTYAGKEILTYPKGNRGVRFMFEAKEADAGEFKYVQFSDHAIAPEKAKHFHLYW
CCEEEEEEECCCEEEECCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCCEEEEEE
GGDSQEKLHKELEHWPTYYGSDLSGREIAQEINAH
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEFTKGVIGNDGDVFMLMK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHCCCCCCCCCEEEEEE
AGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVSDVKKSLTSKKVTIVKGTGNMLLVA
CCCCCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEE
GAGHDHHHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRSITVVENIRDSLSKAYPEKAE
ECCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHCCHHHH
NFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAAFGYMALDYGLNQISINGVTPDA
CCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEECCCCCCC
EPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTLAKEAGVKAAVLSPLEGLTEKEMKA
CCHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHC
GQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTKTVYNGYFKDKEVKDRQLSDWSGSWQS
CHHHHHHHHHCHHHEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHH
VYPYLQNGTLDQVWDYKAKKSKGKMTAAEYKDYYTTGYKTDVEQIKINGKKKTMTFVRNG
HHHHHCCCCHHHHHCCHHHHCCCCEEHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEECC
EKKTFTYTYAGKEILTYPKGNRGVRFMFEAKEADAGEFKYVQFSDHAIAPEKAKHFHLYW
CCEEEEEEECCCEEEECCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCCEEEEEE
GGDSQEKLHKELEHWPTYYGSDLSGREIAQEINAH
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]