Definition Streptococcus pyogenes MGAS5005 chromosome, complete genome.
Accession NC_007297
Length 1,838,554

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The map label for this gene is butA [H]

Identifier: 71910348

GI number: 71910348

Start: 522545

End: 522691

Strand: Direct

Name: butA [H]

Synonym: M5005_Spy_0535

Alternate gene names: 71910348

Gene position: 522545-522691 (Clockwise)

Preceding gene: 71910347

Following gene: 71910349

Centisome position: 28.42

GC content: 37.41

Gene sequence:

>147_bases
ATGGAGCAATTTGCAAAAGATATCACTTTGAAACGCTTGTCTGAACCAGAAGATATTGCTAATGCAGTAGGCTTCTTAGC
GGGAGATGATTCAAATTATATCACTGGACAAACAATAGTTGTCGATGGTGGTATGGTATTCCATTAA

Upstream 100 bases:

>100_bases
CACAGTCAATGCTTACGCACCAGGTATTGTTAAGACACCTATGATGTTTGCTATTGCCCATGAAGTTGGTAAAAATGCAG
GCAAAGATGATGAATGAGGT

Downstream 100 bases:

>100_bases
AAATGATTAATACTGACACTGTGGGTTTCACTCACAGTGTTTTTTAAGAAGTATAAAAAATTATCCTATCTTGGTTATTG
GAGTGATGGCACCTTTGAGG

Product: acetoin dehydrogenase

Products: NA

Alternate protein names: Acetoin(diacetyl) reductase; AR; Meso-2,3-butanediol dehydrogenase [H]

Number of amino acids: Translated: 48; Mature: 48

Protein sequence:

>48_residues
MEQFAKDITLKRLSEPEDIANAVGFLAGDDSNYITGQTIVVDGGMVFH

Sequences:

>Translated_48_residues
MEQFAKDITLKRLSEPEDIANAVGFLAGDDSNYITGQTIVVDGGMVFH
>Mature_48_residues
MEQFAKDITLKRLSEPEDIANAVGFLAGDDSNYITGQTIVVDGGMVFH

Specific function: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014007
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.304 [H]

Molecular weight: Translated: 5215; Mature: 5215

Theoretical pI: Translated: 4.03; Mature: 4.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQFAKDITLKRLSEPEDIANAVGFLAGDDSNYITGQTIVVDGGMVFH
CCCHHHHHHHHHCCCCHHHHHHHCEEECCCCCEECCCEEEECCCEEEC
>Mature Secondary Structure
MEQFAKDITLKRLSEPEDIANAVGFLAGDDSNYITGQTIVVDGGMVFH
CCCHHHHHHHHHCCCCHHHHHHHCEEECCCCCEECCCEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA