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The map label for this gene is ftsX [H]

Identifier: 71910345

GI number: 71910345

Start: 519822

End: 520751

Strand: Direct

Name: ftsX [H]

Synonym: M5005_Spy_0532

Alternate gene names: 71910345

Gene position: 519822-520751 (Clockwise)

Preceding gene: 71910344

Following gene: 71910347

Centisome position: 28.27

GC content: 35.81

Gene sequence:

>930_bases
ATGATTAGATACTTTTTCCGTCATATTTGGGAATCCATTAAAAATCTTAAACGCAACTTTTGGATGACATTTGCTTCAGT
TAGTATGGTGGCTGTTACATTGACTTTAGTTGGTGTTTTTGCGGCGACATTGTTGAATATACAGCGTGTTGCTTCGGGTG
TTGAAAATAATGTCCATATCAATACCTACTTACAAGTTGATTCAACTGATGCTGCAAAAGTTATTCAAAATACTGCCGGT
GAACCTGTTAATAACGATAACTACCACAGTGTTTACGACAAAATTGCTCAGATAAAAGGTGTCAAAAAGATTACATTTTC
TAGCAAGGATGAACAATTGAAAAAATTGCAAGAAACCTTAGGTGATGTTTGGAATATGTATGACCAAGACACTAATCCGC
TCCAAGATATCTATCTTATTGAGACCCAGACGCCTAAACAAGTTAAGGCGATCACTAAAAAGATCAGAACGATTGAAGGC
GTAGAAGCCGCAGATTATGGAGGGATTAACTCCGATAAACTATTTAAGTTTTCAACATTAATTCAAACTTGGGGGCTGAT
CGGAACAGCAATGCTATTATTTGTAGCTGTCTTTCTCATTTCAAACACTATTCGTATGACTATTATGTCTCGTAAACGTG
ACATTGAAATTATGCGGTTAGTTGGTGCTAAAAATTCTTATATTCGAGGGCCTTTCTTTTTTGAAGGGGCTTGGGTTGGC
TTGTTAGGAGCTGTTTTACCATCTCTTCTGATTTATTATGGATATGATCTTGTTTATAAGCATTTTGCACAAGAATTACA
ACGTAATAATCTCTCGATGTATCCGCTTGATCCTTATGTATATTACCTGATTGGTGCTTTGTTTGTCATAGGTATTATGA
TTGGTTCGCTTGGTTCAGTGCTTTCTATGAGACGTTATTTAAAATTCTAA

Upstream 100 bases:

>100_bases
ACACACAACAGTCATATTGTGAATACATTCCGTCATCGTGTTGTTGCTATTGAAGATGGTCGCATAGTACGTGATGAAGA
AAAAGGAGATTATGGTTACG

Downstream 100 bases:

>100_bases
AAAAAGCGCTGCTGACGAAACGTAGCGACCCTCAAAAGTTGGACCTCTTATGTTATTCCAAGGACCTCGTTTTGTATTGC
ACAGGACTGGTCCTTTTCAT

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATLLNIQRVASGVENNVHINTYLQVDSTDAAKVIQNTAG
EPVNNDNYHSVYDKIAQIKGVKKITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEG
VEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIMRLVGAKNSYIRGPFFFEGAWVG
LLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPLDPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF

Sequences:

>Translated_309_residues
MIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATLLNIQRVASGVENNVHINTYLQVDSTDAAKVIQNTAG
EPVNNDNYHSVYDKIAQIKGVKKITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEG
VEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIMRLVGAKNSYIRGPFFFEGAWVG
LLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPLDPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF
>Mature_309_residues
MIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATLLNIQRVASGVENNVHINTYLQVDSTDAAKVIQNTAG
EPVNNDNYHSVYDKIAQIKGVKKITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEG
VEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIMRLVGAKNSYIRGPFFFEGAWVG
LLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPLDPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF

Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap

COG id: COG2177

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789872, Length=257, Percent_Identity=26.4591439688716, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 35229; Mature: 35229

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATLLNIQRVASGVENNVHI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
NTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVKKITFSSKDEQLKKLQETL
EEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHEECCCHHHHHHHHHHHH
GDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEGVEAADYGGINSDKLFKFSTL
HHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHH
IQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIMRLVGAKNSYIRGPFFFEGAWVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECHHHHH
LLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPLDPYVYYLIGALFVIGIMIGSLGSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSMRRYLKF
HHHHHHHCC
>Mature Secondary Structure
MIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATLLNIQRVASGVENNVHI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
NTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVKKITFSSKDEQLKKLQETL
EEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHEECCCHHHHHHHHHHHH
GDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEGVEAADYGGINSDKLFKFSTL
HHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHH
IQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIMRLVGAKNSYIRGPFFFEGAWVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECHHHHH
LLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPLDPYVYYLIGALFVIGIMIGSLGSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSMRRYLKF
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]