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The map label for this gene is ftsW [H]

Identifier: 71910319

GI number: 71910319

Start: 492501

End: 493775

Strand: Direct

Name: ftsW [H]

Synonym: M5005_Spy_0506

Alternate gene names: 71910319

Gene position: 492501-493775 (Clockwise)

Preceding gene: 71910318

Following gene: 71910321

Centisome position: 26.79

GC content: 36.94

Gene sequence:

>1275_bases
ATGAAGATTGATAAAAGGCACCTCTTAAATTATTCTATATTATTGCCTTATTTAATTTTATCGGTGATAGGCTTAATAAT
GGTTTACTCAACCACAAGTGTCAGCTTGATTCAAGCACATGCTAATCCATTTAAATCGGTGATTAACCAGGGAGTTTTTT
GGATAATAAGTCTAGTGGCTATTACATTTATCTATAAATTAAAATTAAATTTTTTAACGAATACAAGGGTATTAACTGTG
GTTATGTTAGGAGAGGCCTTTCTTTTAATCATTGCCCGCTTCTTTACAACTGCTATCAAAGGAGCGCATGGTTGGATTGT
GATCGGACCAGTCAGCTTTCAGCCTGCTGAGTATTTAAAGATCATTATGGTATGGTATTTGGCATTGACCTTTGCTAAGA
TCCAAAAAAACATTAGCCTTTATGATTATCAAGCACTAACTCGTCGAAAATGGTGGCCAACACAATGGAACGATTTACGG
GACTGGCGTGTTTATTCTTTGTTGATGGTACTTTTGGTTGCTGCTCAGCCTGACTTGGGAAATGCTTCCATTATTGTATT
GACAGCCATTATTATGTTTTCTATCAGTGGCATTGGTTACCGATGGTTTTCGGCTATCCTAGTCATGATTACCGGTCTAT
CCACGGTCTTTCTTGGGACTATTGCCGTTATTGGGGTAGAAAGAGTTGCTAAGATTCCTGTTTTTGGCTATGTCGCTAAA
CGTTTTAGTGCCTTTTTTAATCCTTTTCATGACTTGACCGATTCAGGTCACCAATTAGCCAATTCTTACTATGCTATGAG
TAATGGTGGGTGGTTTGGCCAAGGGTTAGGAAATTCCATTGAAAAGCGTGGCTATTTGCCCGAAGCACAGACAGACTTTG
TCTTTTCAGTTGTCATTGAAGAGTTAGGTCTAATAGGAGCAGGGTTTATTTTGGCACTTGTTTTCTTCTTAATTTTACGT
ATTATGAATGTTGGTATTAAAGCAAAAAATCCTTTTAATGCCATGATGGCTTTAGGAGTAGGCGGTATGATGCTCATGCA
AGTCTTTGTTAATATTGGTGGTATCTCAGGCTTAATTCCATCTACTGGTGTTACCTTCCCTTTTTTGTCTCAAGGTGGAA
ATAGCTTACTTGTCTTATCTGTTGCAGTGGGTTTTGTACTAAATATTGATGCTAGCGAAAAGCGAGATGATATATTTAAA
GAAGCTGAATTATCTTATCGAAAGGACACTCGAAAAGAAAATAGTAAAGTTGTAAATATCAAGCAATTTCAATAA

Upstream 100 bases:

>100_bases
TTGGAGCTTCTTTTTTTGAGGATTCTTGACTTTTTCTTTTGTTTGATATAGAAAGATGTTATAATGCTAAATGATTATCT
CAAGAAGTAGAGGGAAAACT

Downstream 100 bases:

>100_bases
TATTCTAAAATCTCCTTTAAGGAGATTTTAGAATATAGACAATCCCAGTTTGATGCTCAAAAAACTTGAACTGCTCTGCT
GATTTCTTATTTTTGCGTGT

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAHANPFKSVINQGVFWIISLVAITFIYKLKLNFLTNTRVLTV
VMLGEAFLLIIARFFTTAIKGAHGWIVIGPVSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRKWWPTQWNDLR
DWRVYSLLMVLLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILVMITGLSTVFLGTIAVIGVERVAKIPVFGYVAK
RFSAFFNPFHDLTDSGHQLANSYYAMSNGGWFGQGLGNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGFILALVFFLILR
IMNVGIKAKNPFNAMMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVGFVLNIDASEKRDDIFK
EAELSYRKDTRKENSKVVNIKQFQ

Sequences:

>Translated_424_residues
MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAHANPFKSVINQGVFWIISLVAITFIYKLKLNFLTNTRVLTV
VMLGEAFLLIIARFFTTAIKGAHGWIVIGPVSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRKWWPTQWNDLR
DWRVYSLLMVLLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILVMITGLSTVFLGTIAVIGVERVAKIPVFGYVAK
RFSAFFNPFHDLTDSGHQLANSYYAMSNGGWFGQGLGNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGFILALVFFLILR
IMNVGIKAKNPFNAMMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVGFVLNIDASEKRDDIFK
EAELSYRKDTRKENSKVVNIKQFQ
>Mature_424_residues
MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAHANPFKSVINQGVFWIISLVAITFIYKLKLNFLTNTRVLTV
VMLGEAFLLIIARFFTTAIKGAHGWIVIGPVSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRKWWPTQWNDLR
DWRVYSLLMVLLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILVMITGLSTVFLGTIAVIGVERVAKIPVFGYVAK
RFSAFFNPFHDLTDSGHQLANSYYAMSNGGWFGQGLGNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGFILALVFFLILR
IMNVGIKAKNPFNAMMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVGFVLNIDASEKRDDIFK
EAELSYRKDTRKENSKVVNIKQFQ

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=402, Percent_Identity=32.089552238806, Blast_Score=175, Evalue=6e-45,
Organism=Escherichia coli, GI1786853, Length=314, Percent_Identity=30.8917197452229, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 47252; Mature: 47252

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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ECCC
>Mature Secondary Structure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ECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]