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The map label for this gene is coaE [H]

Identifier: 71910222

GI number: 71910222

Start: 401593

End: 402273

Strand: Direct

Name: coaE [H]

Synonym: M5005_Spy_0409

Alternate gene names: 71910222

Gene position: 401593-402273 (Clockwise)

Preceding gene: 71910221

Following gene: 71910223

Centisome position: 21.84

GC content: 41.85

Gene sequence:

>681_bases
GTGTCCTCGTTGTGGACAGGCTATTGTCAAATTAAAAGTTGGAGGAAGGGGGACGCACATTTGTCCAAAATGCCAGAAAA
AAAGACTATGATTATTGGCATCACAGGAGGCATTGCATCAGGAAAATCGACTGTGGTTAAGGTCATTAGAAAAGCTGGTT
ATCAGGTGATTGATGCGGATCAAGTGGTTCATGACTTGCAAGAAAAAGGCGGTCGTCTTTACGAGGCTCTTAGAGAAGCT
TTTGGGAATCAGATTTTAAAAGCAGATGGTGAGTTAGATCGCACAAAGCTGTCAGAAATGCTTTTTTCAAACCCAGATAA
TATGGCAACATCCTCAGCCATTCAAAATCAAATCATTAAGGAAGAATTGGCGGCTAAGCGTGACCACTTAGCACAGAGCC
AAGCCATTTTTTTCATGGATATTCCCCTTTTAATGGAATTGGGCTACCAAGACTGGTTTGATGCGATTTGGCTGGTTTAT
GTAGATGCTCAGACACAATTGCAGCGCTTAATGGCTAGAAATCGTTTAGACAAAGGAAAAGCAAGGCAGCGAATAGCCAG
TCAGTTACCAATAGAGGAAAAAAAGCCCTATGCCAGTCTAGTGATTGATAATAGTGGGGATATTGCAGCCTTAATAAAGC
AAGTACAATCTGCGTTGTTGTTATTAGCCAATCCGAGGTAG

Upstream 100 bases:

>100_bases
TTGAAAAGGGCGGTTCGACCGTCCGTACTTACCGTAATGCTTTGGGAGCTGATGGCACCATGCAGGACTATTTGCAGGTT
TATGGTCAAACTGGGAAACC

Downstream 100 bases:

>100_bases
CTAAGCTGAGAGATTCGTATCATAGCTGTCAAAATCAAGCTATTTCTGTCTAAAACTAGCTGGTCCCTTTTAAATTAGCG
CATCAAGGGTTATATGTTAT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MSSLWTGYCQIKSWRKGDAHLSKMPEKKTMIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRLYEALREA
FGNQILKADGELDRTKLSEMLFSNPDNMATSSAIQNQIIKEELAAKRDHLAQSQAIFFMDIPLLMELGYQDWFDAIWLVY
VDAQTQLQRLMARNRLDKGKARQRIASQLPIEEKKPYASLVIDNSGDIAALIKQVQSALLLLANPR

Sequences:

>Translated_226_residues
MSSLWTGYCQIKSWRKGDAHLSKMPEKKTMIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRLYEALREA
FGNQILKADGELDRTKLSEMLFSNPDNMATSSAIQNQIIKEELAAKRDHLAQSQAIFFMDIPLLMELGYQDWFDAIWLVY
VDAQTQLQRLMARNRLDKGKARQRIASQLPIEEKKPYASLVIDNSGDIAALIKQVQSALLLLANPR
>Mature_225_residues
SSLWTGYCQIKSWRKGDAHLSKMPEKKTMIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRLYEALREAF
GNQILKADGELDRTKLSEMLFSNPDNMATSSAIQNQIIKEELAAKRDHLAQSQAIFFMDIPLLMELGYQDWFDAIWLVYV
DAQTQLQRLMARNRLDKGKARQRIASQLPIEEKKPYASLVIDNSGDIAALIKQVQSALLLLANPR

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=188, Percent_Identity=35.1063829787234, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI191252795, Length=188, Percent_Identity=35.1063829787234, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI110227607, Length=201, Percent_Identity=27.8606965174129, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI205277394, Length=168, Percent_Identity=29.7619047619048, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI110227605, Length=168, Percent_Identity=29.7619047619048, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI110227603, Length=168, Percent_Identity=29.7619047619048, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI110227601, Length=168, Percent_Identity=29.7619047619048, Blast_Score=84, Evalue=9e-17,
Organism=Escherichia coli, GI1786292, Length=197, Percent_Identity=32.48730964467, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17554944, Length=197, Percent_Identity=35.5329949238579, Blast_Score=126, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI25143409, Length=180, Percent_Identity=29.4444444444444, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320402, Length=196, Percent_Identity=28.0612244897959, Blast_Score=85, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24644728, Length=185, Percent_Identity=35.6756756756757, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24658602, Length=214, Percent_Identity=29.9065420560748, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 25348; Mature: 25216

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLWTGYCQIKSWRKGDAHLSKMPEKKTMIIGITGGIASGKSTVVKVIRKAGYQVIDAD
CCCCHHHHHHHCCCCCCCHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEECHH
QVVHDLQEKGGRLYEALREAFGNQILKADGELDRTKLSEMLFSNPDNMATSSAIQNQIIK
HHHHHHHHCCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EELAAKRDHLAQSQAIFFMDIPLLMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGK
HHHHHHHHHHHHHCEEEEEEHHHHHHCCHHHHHHHHHHHEECHHHHHHHHHHHHCCCCHH
ARQRIASQLPIEEKKPYASLVIDNSGDIAALIKQVQSALLLLANPR
HHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSLWTGYCQIKSWRKGDAHLSKMPEKKTMIIGITGGIASGKSTVVKVIRKAGYQVIDAD
CCCHHHHHHHCCCCCCCHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEECHH
QVVHDLQEKGGRLYEALREAFGNQILKADGELDRTKLSEMLFSNPDNMATSSAIQNQIIK
HHHHHHHHCCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EELAAKRDHLAQSQAIFFMDIPLLMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGK
HHHHHHHHHHHHHCEEEEEEHHHHHHCCHHHHHHHHHHHEECHHHHHHHHHHHHCCCCHH
ARQRIASQLPIEEKKPYASLVIDNSGDIAALIKQVQSALLLLANPR
HHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]