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The map label for this gene is uppP

Identifier: 71910052

GI number: 71910052

Start: 246148

End: 246987

Strand: Direct

Name: uppP

Synonym: M5005_Spy_0238

Alternate gene names: 71910052

Gene position: 246148-246987 (Clockwise)

Preceding gene: 71910051

Following gene: 71910053

Centisome position: 13.39

GC content: 37.02

Gene sequence:

>840_bases
ATGTTAATTATCGAATTGCTAAAAGCCATTTTCTTTGGCATCATTGAGGGAATCACAGAATGGTTACCAGTTTCAAGCAC
TGGTCACCTCATTTTGGTGCAGGAATTTATCCGACTAAATCAGGATAAGGCTTTTATAGAAATGTTTAATATCGTTATTC
AATTAGGGGCGATTATCGCTGTTATGTTGATTTATTTTGAACGTCTCAATCCCTTTCAACCTGGGAAAACAGCAAGAGAA
GTACAGCTTACCTGGCAATTATGGCTAAAAGTGGTGATTGCGTGTATTCCTTCTATTTTAATAGCGGTTCCTCTTGATAA
TTGGTTTGAAGCACATTTTTATTTTATGGTTCCGATTGCCATCGCTTTAATCGTCTACGGGATTGCCTTTATCTGGATTG
AAAAACGAAATGCTCAACAAGAACCTGCTGTCACTGAATTAGCTAGAATGTCTTACAAAACAGCTTTCTTCATTGGTTGT
TTTCAAGTCTTAAGTATTGTGCCTGGTACTAGTCGATCAGGGGCTACCATCTTAGGAGCTATTATTTTAGGAACTAGTCG
AACAGTGGCCGCTGATTTCACCTTCTTTTTGGCCATTCCTACCATGTTTGGATATAGTGGATTAAAGGCTGTAAAATTTT
TCCTTGATGGCCATCACCTTGATTTTGCACAAGTCCTTATTCTTTTAGTGGCTAGCTTGACCGCTTTTGTGGTTAGTTTA
TTGGCGATTAGGTTCTTGACAGATTATGTTAAGAAACACGATTTCACCATTTTTGGGAAATACCGTATTGTGTTAGGAAG
CCTTTTACTTATTTATAGCTTCTTTAAATTTGTTTTTTAA

Upstream 100 bases:

>100_bases
GGATTAGTGGTGGTGGCGGCGGCGGTGCCTTTTAAAAAAGCTGCTTGGCATTAATCACAGTTTAGAAAATCACAATAAGA
GTGGTTAATAAGGAGAAAAC

Downstream 100 bases:

>100_bases
ACTTACATATCGTTTAGGATGTTGCGACAGACCTTGGGGACTGTCGCTTTTTAAATTTCCTTTTGTAGACGAGGAGTTAG
TCATAAATTGCGAAATTACA

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKAFIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTARE
VQLTWQLWLKVVIACIPSILIAVPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKRNAQQEPAVTELARMSYKTAFFIGC
FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGHHLDFAQVLILLVASLTAFVVSL
LAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFKFVF

Sequences:

>Translated_279_residues
MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKAFIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTARE
VQLTWQLWLKVVIACIPSILIAVPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKRNAQQEPAVTELARMSYKTAFFIGC
FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGHHLDFAQVLILLVASLTAFVVSL
LAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFKFVF
>Mature_279_residues
MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKAFIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTARE
VQLTWQLWLKVVIACIPSILIAVPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKRNAQQEPAVTELARMSYKTAFFIGC
FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGHHLDFAQVLILLVASLTAFVVSL
LAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFKFVF

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=275, Percent_Identity=35.2727272727273, Blast_Score=148, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_STRP1 (P67392)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268631.1
- RefSeq:   YP_281602.1
- ProteinModelPortal:   P67392
- EnsemblBacteria:   EBSTRT00000001323
- EnsemblBacteria:   EBSTRT00000029044
- GeneID:   3572666
- GeneID:   900577
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0280
- KEGG:   spz:M5005_Spy_0238
- GeneTree:   EBGT00050000027344
- HOGENOM:   HBG391969
- OMA:   VATIPVM
- ProtClustDB:   PRK00281
- BioCyc:   SPYO160490:SPY0280-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0238-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 31538; Mature: 31538

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0xc489818)-; HASH(0xc316b4c)-; HASH(0xbfe48a4)-; HASH(0xb09ffe8)-; HASH(0xbbc61c0)-; HASH(0xc95c328)-; HASH(0x403d49ac)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKAFIEMFNIVIQLGAIIA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIAVPLDNWFEAHFYFMVPIA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
IALIVYGIAFIWIEKRNAQQEPAVTELARMSYKTAFFIGCFQVLSIVPGTSRSGATILGA
HHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
IILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGHHLDFAQVLILLVASLTAFVVSL
HHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFKFVF
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11296296