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The map label for this gene is ydcA [H]

Identifier: 71910005

GI number: 71910005

Start: 197506

End: 198177

Strand: Direct

Name: ydcA [H]

Synonym: M5005_Spy_0191

Alternate gene names: 71910005

Gene position: 197506-198177 (Clockwise)

Preceding gene: 71910004

Following gene: 71910009

Centisome position: 10.74

GC content: 38.24

Gene sequence:

>672_bases
ATGACACAGTTATTAAAACGATATCCTATTACTATTTTCCTTTTAGGGTTAACAGGCTTAATTTTTATAGCAATGCAAGT
GGTATATGGACATTTAGCAACTGGTGCTCAAGCTATTTATCAAGTTGGAGGTATGTTTGGATTACTAGTAAAAGCAATGC
CAGACCAGTTGTGGCGATTGGTGACTCCGATATTTATTCATATCGGCTTTGGTCATTTTTTTGTCAATGGATTAACACTA
TATTTTGTTGGTCAAATCGTCGAAGACCTCTGGGGCTCACGCCGTTTTTTATTACTTTATGTTTTATCAGGTGTTATGGG
CAATGCCTTTACTTTTTGGTTGACTCCTGAAACAGTAGCTGCAGGAGCATCGACGTCGTTATTTGGACTTTTTGCTGCTA
TTGTAGTATTGAGTTTTTTGGGTAAGAACCAAGCGTTGAAAGATTTGGGCAAGTCATACCAGACGTTAATTGTAGTCAAT
TTACTGATGAATCTTTTTATGCCAAACGTGAGTATGGCAGGCCATATTGGCGGTGTCGTGGGTGGTGCGTTACTGAGTAT
AGTTTTTCCAACTAAGATGAGAGTGATAACAGTGAAGAAAACCAAGCGAATGTTGGCTTTAGTGAGCTATGGTATTATTT
TGGTTGGTGTGTTAGTGCTTGGGTTTTTATAA

Upstream 100 bases:

>100_bases
TTTATTAGTGGATGTTGTTAGCAATCAAGCTTATCAGCGGGCCAATACGATTGCCAAATCAAACGATTTATGATATTGCT
GTTTAGGAGGTTTATCTTAG

Downstream 100 bases:

>100_bases
AAATAAGTGAGTGGTTAGCACTGTTACTTCTCAGATGGCTAGTAGGATGAAATGACTTAAAAACCATAAAAATAAGGAGG
GATTTTCCCTCCTTATTTTT

Product: rhomboid family integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MTQLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGGMFGLLVKAMPDQLWRLVTPIFIHIGFGHFFVNGLTL
YFVGQIVEDLWGSRRFLLLYVLSGVMGNAFTFWLTPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLGKSYQTLIVVN
LLMNLFMPNVSMAGHIGGVVGGALLSIVFPTKMRVITVKKTKRMLALVSYGIILVGVLVLGFL

Sequences:

>Translated_223_residues
MTQLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGGMFGLLVKAMPDQLWRLVTPIFIHIGFGHFFVNGLTL
YFVGQIVEDLWGSRRFLLLYVLSGVMGNAFTFWLTPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLGKSYQTLIVVN
LLMNLFMPNVSMAGHIGGVVGGALLSIVFPTKMRVITVKKTKRMLALVSYGIILVGVLVLGFL
>Mature_222_residues
TQLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGGMFGLLVKAMPDQLWRLVTPIFIHIGFGHFFVNGLTLY
FVGQIVEDLWGSRRFLLLYVLSGVMGNAFTFWLTPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLGKSYQTLIVVNL
LMNLFMPNVSMAGHIGGVVGGALLSIVFPTKMRVITVKKTKRMLALVSYGIILVGVLVLGFL

Specific function: Unknown

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Homo sapiens, GI93352558, Length=184, Percent_Identity=28.804347826087, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI301069362, Length=184, Percent_Identity=28.804347826087, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI190341097, Length=160, Percent_Identity=30, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115532986, Length=187, Percent_Identity=31.5508021390374, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI133901888, Length=187, Percent_Identity=31.5508021390374, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF01694 Rhomboid [H]

EC number: NA

Molecular weight: Translated: 24293; Mature: 24162

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGGMFGLLVKAMPDQLWRL
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTPIFIHIGFGHFFVNGLTLYFVGQIVEDLWGSRRFLLLYVLSGVMGNAFTFWLTPETVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECHHHHH
AGASTSLFGLFAAIVVLSFLGKNQALKDLGKSYQTLIVVNLLMNLFMPNVSMAGHIGGVV
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GGALLSIVFPTKMRVITVKKTKRMLALVSYGIILVGVLVLGFL
HHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGGMFGLLVKAMPDQLWRL
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTPIFIHIGFGHFFVNGLTLYFVGQIVEDLWGSRRFLLLYVLSGVMGNAFTFWLTPETVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECHHHHH
AGASTSLFGLFAAIVVLSFLGKNQALKDLGKSYQTLIVVNLLMNLFMPNVSMAGHIGGVV
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GGALLSIVFPTKMRVITVKKTKRMLALVSYGIILVGVLVLGFL
HHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9341680; 9384377 [H]