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The map label for this gene is 71909923

Identifier: 71909923

GI number: 71909923

Start: 120206

End: 121228

Strand: Direct

Name: 71909923

Synonym: M5005_Spy_0109

Alternate gene names: NA

Gene position: 120206-121228 (Clockwise)

Preceding gene: 71909922

Following gene: 71909924

Centisome position: 6.54

GC content: 35.0

Gene sequence:

>1023_bases
ATGAAATTACGTCACTTACTATTAACGGGAGCAGCCCTAACTAGTTTTGCTGCTACAACAGTTCACGGGGAGACTGTTGT
AAACGGAGCCAAACTAACAGTTACAAAAAACCTTGATTTAGTTAATAGCAATGCATTAATTCCAAATACAGATTTTACAT
TTAAAATCGAACCTGATACTACTGTCAACGAAGACGGAAATAAGTTTAAAGGTGTAGCTTTGAACACACCGATGACTAAA
GTCACTTACACCAATTCAGATAAAGGTGGATCAAATACGAAAACTGCAGAATTTGATTTTTCAGAAGTTACTTTTGAAAA
ACCAGGTGTTTATTATTACAAAGTAACTGAGGAGAAGATAGATAAAGTTCCTGGTGTTTCTTATGATACAACATCTTACA
CTGTTCAAGTTCATGTCTTGTGGAATGAAGAGCAACAAAAACCAGTAGCTACTTATATTGTTGGTTATAAAGAAGGTAGT
AAGGTGCCAATTCAGTTCAAAAATAGCTTAGATTCTACTACATTAACGGTGAAGAAAAAAGTTTCAGGTACCGGTGGAGA
TCGCTCTAAAGATTTTAATTTTGGTCTGACTTTAAAAGCAAATCAGTATTATAAGGCGTCAGAAAAAGTCATGATTGAGA
AGACAACTAAAGGTGGTCAAGCTCCTGTTCAAACAGAGGCTAGTATAGATCAACTCTATCATTTTACCTTGAAAGATGGT
GAATCAATCAAAGTCACAAATCTTCCAGTAGGTGTGGATTATGTTGTCACTGAAGACGATTACAAATCAGAAAAATATAC
AACCAACGTGGAAGTTAGTCCTCAAGATGGAGCTGTAAAAAATATCGCAGGTAATTCAACTGAACAAGAGACATCTACTG
ATAAAGATATGACCATTACTTTTACAAATAAAAAAGACTTTGAAGTGCCAACAGGAGTAGCAATGACTGTGGCACCATAT
ATTGCTTTAGGAATTGTAGCAGTTGGTGGAGCTCTTTACTTTGTTAAAAAGAAAAATGCTTAA

Upstream 100 bases:

>100_bases
AAGATGCAATTGCTAAAGATGCTATAAAAGGCACGATTAATACACTTATTCGATTAAGAAACCATTAAGCTAAAGGCTTA
TTTAAAAAAGGAGAGAAACA

Downstream 100 bases:

>100_bases
ATTATTATTATGATAGTAAGACTGATTAAGCTCCTTGACAAGTTGATAAACGTCATTGTTCTTTGTTTCTTCTTTCTTTG
TTTATTGATTGCGGCACTTG

Product: fibronectin-binding protein

Products: NA

Alternate protein names: Lancefield T antigen; Pilus backbone structural protein

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKLRHLLLTGAALTSFAATTVHGETVVNGAKLTVTKNLDLVNSNALIPNTDFTFKIEPDTTVNEDGNKFKGVALNTPMTK
VTYTNSDKGGSNTKTAEFDFSEVTFEKPGVYYYKVTEEKIDKVPGVSYDTTSYTVQVHVLWNEEQQKPVATYIVGYKEGS
KVPIQFKNSLDSTTLTVKKKVSGTGGDRSKDFNFGLTLKANQYYKASEKVMIEKTTKGGQAPVQTEASIDQLYHFTLKDG
ESIKVTNLPVGVDYVVTEDDYKSEKYTTNVEVSPQDGAVKNIAGNSTEQETSTDKDMTITFTNKKDFEVPTGVAMTVAPY
IALGIVAVGGALYFVKKKNA

Sequences:

>Translated_340_residues
MKLRHLLLTGAALTSFAATTVHGETVVNGAKLTVTKNLDLVNSNALIPNTDFTFKIEPDTTVNEDGNKFKGVALNTPMTK
VTYTNSDKGGSNTKTAEFDFSEVTFEKPGVYYYKVTEEKIDKVPGVSYDTTSYTVQVHVLWNEEQQKPVATYIVGYKEGS
KVPIQFKNSLDSTTLTVKKKVSGTGGDRSKDFNFGLTLKANQYYKASEKVMIEKTTKGGQAPVQTEASIDQLYHFTLKDG
ESIKVTNLPVGVDYVVTEDDYKSEKYTTNVEVSPQDGAVKNIAGNSTEQETSTDKDMTITFTNKKDFEVPTGVAMTVAPY
IALGIVAVGGALYFVKKKNA
>Mature_340_residues
MKLRHLLLTGAALTSFAATTVHGETVVNGAKLTVTKNLDLVNSNALIPNTDFTFKIEPDTTVNEDGNKFKGVALNTPMTK
VTYTNSDKGGSNTKTAEFDFSEVTFEKPGVYYYKVTEEKIDKVPGVSYDTTSYTVQVHVLWNEEQQKPVATYIVGYKEGS
KVPIQFKNSLDSTTLTVKKKVSGTGGDRSKDFNFGLTLKANQYYKASEKVMIEKTTKGGQAPVQTEASIDQLYHFTLKDG
ESIKVTNLPVGVDYVVTEDDYKSEKYTTNVEVSPQDGAVKNIAGNSTEQETSTDKDMTITFTNKKDFEVPTGVAMTVAPY
IALGIVAVGGALYFVKKKNA

Specific function: Major component of the pilus. A stack of the pilin subunits, joined by intermolecular isopeptide bonds, forms the pilus. The pilus is required for bacterial adhesion to host cells, for bacterial aggregation, and for biofilm formation

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor. Fimbrium. Note=Attached to the cell wall by a peptidoglycan anchor

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Streptococcus pilin family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PILIN_STRP1 (Q9A1S2)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268517.1
- RefSeq:   YP_281473.1
- PDB:   3B2M
- PDB:   3GLD
- PDB:   3GLE
- PDBsum:   3B2M
- PDBsum:   3GLD
- PDBsum:   3GLE
- ProteinModelPortal:   Q9A1S2
- SMR:   Q9A1S2
- EnsemblBacteria:   EBSTRT00000001095
- EnsemblBacteria:   EBSTRT00000027552
- GeneID:   3572810
- GeneID:   900460
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0128
- KEGG:   spz:M5005_Spy_0109
- GeneTree:   EBGT00050000026672
- HOGENOM:   HBG698074
- OMA:   WTVDVYV
- ProtClustDB:   CLSK698223
- BioCyc:   SPYO160490:SPY0128-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0109-MONOMER
- GO:   GO:0009289
- InterPro:   IPR017503
- InterPro:   IPR022464
- TIGRFAMs:   TIGR03065
- TIGRFAMs:   TIGR03786

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 37188; Mature: 37188

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRHLLLTGAALTSFAATTVHGETVVNGAKLTVTKNLDLVNSNALIPNTDFTFKIEPDT
CCCEEEEEECHHHHHHEEEEECCCEEECCEEEEEEECCEEECCCEECCCCCEEEEECCCC
TVNEDGNKFKGVALNTPMTKVTYTNSDKGGSNTKTAEFDFSEVTFEKPGVYYYKVTEEKI
CCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCEEEEECHHHEEEECCCEEEEEECHHHH
DKVPGVSYDTTSYTVQVHVLWNEEQQKPVATYIVGYKEGSKVPIQFKNSLDSTTLTVKKK
HHCCCCCCCCCEEEEEEEEEECCCCCCCEEEEEEEECCCCCCCEEECCCCCCEEEEEEEE
VSGTGGDRSKDFNFGLTLKANQYYKASEKVMIEKTTKGGQAPVQTEASIDQLYHFTLKDG
ECCCCCCCCCCCEEEEEEECCCEECCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEECCC
ESIKVTNLPVGVDYVVTEDDYKSEKYTTNVEVSPQDGAVKNIAGNSTEQETSTDKDMTIT
CEEEEEECCCCEEEEEECCCCCCCEEEEEEEECCCCCCEEECCCCCCCCCCCCCCCEEEE
FTNKKDFEVPTGVAMTVAPYIALGIVAVGGALYFVKKKNA
ECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCC
>Mature Secondary Structure
MKLRHLLLTGAALTSFAATTVHGETVVNGAKLTVTKNLDLVNSNALIPNTDFTFKIEPDT
CCCEEEEEECHHHHHHEEEEECCCEEECCEEEEEEECCEEECCCEECCCCCEEEEECCCC
TVNEDGNKFKGVALNTPMTKVTYTNSDKGGSNTKTAEFDFSEVTFEKPGVYYYKVTEEKI
CCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCEEEEECHHHEEEECCCEEEEEECHHHH
DKVPGVSYDTTSYTVQVHVLWNEEQQKPVATYIVGYKEGSKVPIQFKNSLDSTTLTVKKK
HHCCCCCCCCCEEEEEEEEEECCCCCCCEEEEEEEECCCCCCCEEECCCCCCEEEEEEEE
VSGTGGDRSKDFNFGLTLKANQYYKASEKVMIEKTTKGGQAPVQTEASIDQLYHFTLKDG
ECCCCCCCCCCCEEEEEEECCCEECCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEECCC
ESIKVTNLPVGVDYVVTEDDYKSEKYTTNVEVSPQDGAVKNIAGNSTEQETSTDKDMTIT
CEEEEEECCCCEEEEEECCCCCCCEEEEEEEECCCCCCEEECCCCCCCCCCCCCCCEEEE
FTNKKDFEVPTGVAMTVAPYIALGIVAVGGALYFVKKKNA
ECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296