| Definition | Streptococcus pyogenes MGAS5005 chromosome, complete genome. |
|---|---|
| Accession | NC_007297 |
| Length | 1,838,554 |
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The map label for this gene is 71909921
Identifier: 71909921
GI number: 71909921
Start: 117335
End: 119623
Strand: Direct
Name: 71909921
Synonym: M5005_Spy_0107
Alternate gene names: NA
Gene position: 117335-119623 (Clockwise)
Preceding gene: 71909916
Following gene: 71909922
Centisome position: 6.38
GC content: 34.73
Gene sequence:
>2289_bases TTGAGAGGAGAGAAAATGAAAAAAACAAGGTTTCCAAATAAGCTTAATACTCTTAATACTCAAAGGGTATTAAGTAAAAA CTCAAAACGATTTACTGTCACTTTAGTGGGAGTCTTTTTAATGATCTTCGCTTTGGTAACTTCCATGGTTGGTGCTAAGA CTGTTTTTGGTTTAGTAGAATCCTCGACGCCAAACGCAATAAATCCAGATTCAAGTTCGGAATACAGATGGTATGGATAT GAATCTTATGTAAGAGGGCATCCATATTATAAACAGTTTAGAGTAGCACACGATTTAAGGGTTAACTTAGAAGGAAGTAG AAGTTATCAAGTTTATTGCTTTAATTTAAAGAAAGCATTTCCTCTCGGATCAGATAGTAGTGTTAAAAAGTGGTATAAAA AACATGATGGAATCTCTACAAAATTTGAAGATTATGCGATAAGCCCTAGAATTACGGGAGATGAGCTAAATCAGAAGTTA CGAGCTGTTATGTATAATGGACATCCACAAAATGCCAATGGTATTATGGAAGGCTTGGAACCCTTGAATGCTATCAGAGT TACACAAGAGGCGGTATGGTACTATTCTGATAATGCTCCTATTTCTAATCCAGATGAAAGTTTTAAAAGGGAGTCAGAAA GTAACTTGGTTAGTACTTCTCAATTATCTTTGATGCGTCAAGCTTTGAAGCAACTGATTGATCCGAATTTGGCAACTAAA ATGCCAAAACAAGTTCCGGATGATTTTCAGCTAAGTATTTTTGAGTCTGAGGACAAGGGAGATAAATATAATAAAGGATA CCAAAATCTTTTGAGTGGTGGTTTAGTTCCTACTAAACCACCAACTCCAGGAGACCCACCAATGCCTCCAAATCAACCTC AAACGACTTCAGTACTTATTAGAAAGTATGCTATAGGTGATTACTCTAAATTGCTTGAAGGTGCAACATTACAGTTGACA GGGGATAACGTGAATAGTTTTCAAGCGAGAGTGTTTAGCAGTAATGATATTGGAGAAAGAATTGAACTATCAGATGGAAC TTATACTTTAACTGAATTGAATTCTCCAGCTGGTTATAGTATCGCAGAGCCAATCACTTTTAAGGTTGAAGCTGGCAAAG TGTATACTATTATTGATGGAAAACAGATTGAAAATCCCAATAAAGAGATAGTAGAGCCTTACTCAGTAGAAGCATATAAT GATTTTGAAGAATTTAGCGTTTTAACTACACAAAACTATGCAAAATTTTATTATGCAAAAAATAAAAATGGAAGTTCACA GGTTGTCTATTGCTTTAATGCAGATCTAAAATCTCCACCAGACTCTGAAGATGGTGGGAAAACAATGACTCCAGACTTTA CAACAGGAGAAGTAAAATACACTCATATTGCAGGTCGTGACCTCTTTAAATATACTGTGAAACCAAGAGATACCGATCCT GACACTTTCTTAAAACATATCAAAAAAGTAATTGAGAAGGGTTACAGGGAAAAAGGACAAGCTATTGAGTATAGTGGTCT AACTGAGACACAATTGCGTGCGGCTACTCAGTTAGCAATATATTATTTCACTGATAGTGCTGAATTAGATAAGGATAAAC TAAAAGACTATCATGGTTTTGGAGACATGAATGATAGTACTTTAGCAGTTGCTAAAATCCTTGTAGAATACGCTCAAGAT AGTAATCCTCCACAGCTAACTGACCTTGATTTCTTTATTCCGAATAACAATAAATATCAATCCCTTATTGGAACTCAGTG GCATCCAGAAGATTTAGTTGATATTATTCGTATGGAAGATAAAAAAGAAGTTATACCTGTAACTCATAATTTAACATTGA GAAAAACGGTGACTGGTTTAGCTGGTGACAGAACTAAAGATTTCCATTTTGAAATTGAATTAAAAAATAATAAGCAAGAA TTGCTTTCTCAAACTGTTAAAACAGATAAAACAAACCTCGAATTTAAAGATGGTAAAGCAACCATTAATTTAAAACATGG GGAAAGTTTAACACTTCAAGGTTTACCAGAAGGTTATTCTTACCTTGTCAAAGAAACAGATTCTGAAGGCTATAAGGTTA AAGTTAATAGCCAAGAAGTAGCAAATGCTACAGTTTCAAAAACAGGAATAACAAGTGATGAGACACTTGCTTTTGAAAAT AATAAAGAGCCTGTTGTTCCTACAGGAGTTGATCAAAAGATCAATGGCTATCTAGCTTTGATAGTTATCGCTGGTATCAG TTTGGGGATCTGGGGAATTCACACGATAAGGATAAGAAAACATGACTAG
Upstream 100 bases:
>100_bases GCAATATTTTCTCAAAAAATCATTTTCAAAAACACTAATTTGGTGAAAAACTTAGTACGAATATATTTCTTTGACTTCAA TAGAATGATATGATGTCACA
Downstream 100 bases:
>100_bases AGCTGATTTCAGAACTTCTAATTCATCTGGAGAACTTAACAAACTATCATTTTCAGATAAAGAAGCAATAAAGCCCTTAC TCATAGGACTTGTTAAAAAA
Product: fibronectin-binding protein
Products: NA
Alternate protein names: Lancefield T antigen; Pilus backbone structural protein [H]
Number of amino acids: Translated: 762; Mature: 762
Protein sequence:
>762_residues MRGEKMKKTRFPNKLNTLNTQRVLSKNSKRFTVTLVGVFLMIFALVTSMVGAKTVFGLVESSTPNAINPDSSSEYRWYGY ESYVRGHPYYKQFRVAHDLRVNLEGSRSYQVYCFNLKKAFPLGSDSSVKKWYKKHDGISTKFEDYAISPRITGDELNQKL RAVMYNGHPQNANGIMEGLEPLNAIRVTQEAVWYYSDNAPISNPDESFKRESESNLVSTSQLSLMRQALKQLIDPNLATK MPKQVPDDFQLSIFESEDKGDKYNKGYQNLLSGGLVPTKPPTPGDPPMPPNQPQTTSVLIRKYAIGDYSKLLEGATLQLT GDNVNSFQARVFSSNDIGERIELSDGTYTLTELNSPAGYSIAEPITFKVEAGKVYTIIDGKQIENPNKEIVEPYSVEAYN DFEEFSVLTTQNYAKFYYAKNKNGSSQVVYCFNADLKSPPDSEDGGKTMTPDFTTGEVKYTHIAGRDLFKYTVKPRDTDP DTFLKHIKKVIEKGYREKGQAIEYSGLTETQLRAATQLAIYYFTDSAELDKDKLKDYHGFGDMNDSTLAVAKILVEYAQD SNPPQLTDLDFFIPNNNKYQSLIGTQWHPEDLVDIIRMEDKKEVIPVTHNLTLRKTVTGLAGDRTKDFHFEIELKNNKQE LLSQTVKTDKTNLEFKDGKATINLKHGESLTLQGLPEGYSYLVKETDSEGYKVKVNSQEVANATVSKTGITSDETLAFEN NKEPVVPTGVDQKINGYLALIVIAGISLGIWGIHTIRIRKHD
Sequences:
>Translated_762_residues MRGEKMKKTRFPNKLNTLNTQRVLSKNSKRFTVTLVGVFLMIFALVTSMVGAKTVFGLVESSTPNAINPDSSSEYRWYGY ESYVRGHPYYKQFRVAHDLRVNLEGSRSYQVYCFNLKKAFPLGSDSSVKKWYKKHDGISTKFEDYAISPRITGDELNQKL RAVMYNGHPQNANGIMEGLEPLNAIRVTQEAVWYYSDNAPISNPDESFKRESESNLVSTSQLSLMRQALKQLIDPNLATK MPKQVPDDFQLSIFESEDKGDKYNKGYQNLLSGGLVPTKPPTPGDPPMPPNQPQTTSVLIRKYAIGDYSKLLEGATLQLT GDNVNSFQARVFSSNDIGERIELSDGTYTLTELNSPAGYSIAEPITFKVEAGKVYTIIDGKQIENPNKEIVEPYSVEAYN DFEEFSVLTTQNYAKFYYAKNKNGSSQVVYCFNADLKSPPDSEDGGKTMTPDFTTGEVKYTHIAGRDLFKYTVKPRDTDP DTFLKHIKKVIEKGYREKGQAIEYSGLTETQLRAATQLAIYYFTDSAELDKDKLKDYHGFGDMNDSTLAVAKILVEYAQD SNPPQLTDLDFFIPNNNKYQSLIGTQWHPEDLVDIIRMEDKKEVIPVTHNLTLRKTVTGLAGDRTKDFHFEIELKNNKQE LLSQTVKTDKTNLEFKDGKATINLKHGESLTLQGLPEGYSYLVKETDSEGYKVKVNSQEVANATVSKTGITSDETLAFEN NKEPVVPTGVDQKINGYLALIVIAGISLGIWGIHTIRIRKHD >Mature_762_residues MRGEKMKKTRFPNKLNTLNTQRVLSKNSKRFTVTLVGVFLMIFALVTSMVGAKTVFGLVESSTPNAINPDSSSEYRWYGY ESYVRGHPYYKQFRVAHDLRVNLEGSRSYQVYCFNLKKAFPLGSDSSVKKWYKKHDGISTKFEDYAISPRITGDELNQKL RAVMYNGHPQNANGIMEGLEPLNAIRVTQEAVWYYSDNAPISNPDESFKRESESNLVSTSQLSLMRQALKQLIDPNLATK MPKQVPDDFQLSIFESEDKGDKYNKGYQNLLSGGLVPTKPPTPGDPPMPPNQPQTTSVLIRKYAIGDYSKLLEGATLQLT GDNVNSFQARVFSSNDIGERIELSDGTYTLTELNSPAGYSIAEPITFKVEAGKVYTIIDGKQIENPNKEIVEPYSVEAYN DFEEFSVLTTQNYAKFYYAKNKNGSSQVVYCFNADLKSPPDSEDGGKTMTPDFTTGEVKYTHIAGRDLFKYTVKPRDTDP DTFLKHIKKVIEKGYREKGQAIEYSGLTETQLRAATQLAIYYFTDSAELDKDKLKDYHGFGDMNDSTLAVAKILVEYAQD SNPPQLTDLDFFIPNNNKYQSLIGTQWHPEDLVDIIRMEDKKEVIPVTHNLTLRKTVTGLAGDRTKDFHFEIELKNNKQE LLSQTVKTDKTNLEFKDGKATINLKHGESLTLQGLPEGYSYLVKETDSEGYKVKVNSQEVANATVSKTGITSDETLAFEN NKEPVVPTGVDQKINGYLALIVIAGISLGIWGIHTIRIRKHD
Specific function: Major component of the pilus. A stack of the pilin subunits, joined by intermolecular isopeptide bonds, forms the pilus. The pilus is required for bacterial adhesion to host cells, for bacterial aggregation, and for biofilm formation [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Secreted, cell wall; Peptidoglycan-anchor. Fimbrium. Note=Attached to the cell wall by a peptidoglycan anchor [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the Streptococcus pilin family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR017503 - InterPro: IPR022464 [H]
Pfam domain/function: NA
EC number: NA
Molecular weight: Translated: 85745; Mature: 85745
Theoretical pI: Translated: 6.59; Mature: 6.59
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRGEKMKKTRFPNKLNTLNTQRVLSKNSKRFTVTLVGVFLMIFALVTSMVGAKTVFGLVE CCCCCCHHHCCCCHHHCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHC SSTPNAINPDSSSEYRWYGYESYVRGHPYYKQFRVAHDLRVNLEGSRSYQVYCFNLKKAF CCCCCCCCCCCCCCEEEECHHHHHCCCCCHHHHEEEEEEEEEECCCCEEEEEEEEEEECC PLGSDSSVKKWYKKHDGISTKFEDYAISPRITGDELNQKLRAVMYNGHPQNANGIMEGLE CCCCCHHHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHEEECCCCCCCHHHHHHHH PLNAIRVTQEAVWYYSDNAPISNPDESFKRESESNLVSTSQLSLMRQALKQLIDPNLATK HHHHHEEEEEEEEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHH MPKQVPDDFQLSIFESEDKGDKYNKGYQNLLSGGLVPTKPPTPGDPPMPPNQPQTTSVLI CHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHH RKYAIGDYSKLLEGATLQLTGDNVNSFQARVFSSNDIGERIELSDGTYTLTELNSPAGYS HHHHCCCHHHHHCCCEEEEECCCCCCEEEEEECCCCCCCEEEECCCEEEEEECCCCCCCC IAEPITFKVEAGKVYTIIDGKQIENPNKEIVEPYSVEAYNDFEEFSVLTTQNYAKFYYAK CCCCEEEEEECCEEEEEECCCCCCCCCHHHCCCCEECCCCCHHHHEEEEECCCEEEEEEE NKNGSSQVVYCFNADLKSPPDSEDGGKTMTPDFTTGEVKYTHIAGRDLFKYTVKPRDTDP CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCH DTFLKHIKKVIEKGYREKGQAIEYSGLTETQLRAATQLAIYYFTDSAELDKDKLKDYHGF HHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHEEEEEEEEEECCCCCCHHHHHHHCCC GDMNDSTLAVAKILVEYAQDSNPPQLTDLDFFIPNNNKYQSLIGTQWHPEDLVDIIRMED CCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHCCCCCCHHHHHHHHHCCC KKEVIPVTHNLTLRKTVTGLAGDRTKDFHFEIELKNNKQELLSQTVKTDKTNLEFKDGKA CCCEEEEECCEEEEHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCEEEECCEE TINLKHGESLTLQGLPEGYSYLVKETDSEGYKVKVNSQEVANATVSKTGITSDETLAFEN EEEEECCCEEEECCCCCCCEEHEEECCCCCEEEEECCHHHHCCCHHCCCCCCCCEEEECC NKEPVVPTGVDQKINGYLALIVIAGISLGIWGIHTIRIRKHD CCCCCCCCCCCCHHCCEEEEEEHHHHHCCEEEEEEEEEEECC >Mature Secondary Structure MRGEKMKKTRFPNKLNTLNTQRVLSKNSKRFTVTLVGVFLMIFALVTSMVGAKTVFGLVE CCCCCCHHHCCCCHHHCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHC SSTPNAINPDSSSEYRWYGYESYVRGHPYYKQFRVAHDLRVNLEGSRSYQVYCFNLKKAF CCCCCCCCCCCCCCEEEECHHHHHCCCCCHHHHEEEEEEEEEECCCCEEEEEEEEEEECC PLGSDSSVKKWYKKHDGISTKFEDYAISPRITGDELNQKLRAVMYNGHPQNANGIMEGLE CCCCCHHHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHEEECCCCCCCHHHHHHHH PLNAIRVTQEAVWYYSDNAPISNPDESFKRESESNLVSTSQLSLMRQALKQLIDPNLATK HHHHHEEEEEEEEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHH MPKQVPDDFQLSIFESEDKGDKYNKGYQNLLSGGLVPTKPPTPGDPPMPPNQPQTTSVLI CHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHH RKYAIGDYSKLLEGATLQLTGDNVNSFQARVFSSNDIGERIELSDGTYTLTELNSPAGYS HHHHCCCHHHHHCCCEEEEECCCCCCEEEEEECCCCCCCEEEECCCEEEEEECCCCCCCC IAEPITFKVEAGKVYTIIDGKQIENPNKEIVEPYSVEAYNDFEEFSVLTTQNYAKFYYAK CCCCEEEEEECCEEEEEECCCCCCCCCHHHCCCCEECCCCCHHHHEEEEECCCEEEEEEE NKNGSSQVVYCFNADLKSPPDSEDGGKTMTPDFTTGEVKYTHIAGRDLFKYTVKPRDTDP CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCH DTFLKHIKKVIEKGYREKGQAIEYSGLTETQLRAATQLAIYYFTDSAELDKDKLKDYHGF HHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHEEEEEEEEEECCCCCCHHHHHHHCCC GDMNDSTLAVAKILVEYAQDSNPPQLTDLDFFIPNNNKYQSLIGTQWHPEDLVDIIRMED CCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHCCCCCCHHHHHHHHHCCC KKEVIPVTHNLTLRKTVTGLAGDRTKDFHFEIELKNNKQELLSQTVKTDKTNLEFKDGKA CCCEEEEECCEEEEHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCEEEECCEE TINLKHGESLTLQGLPEGYSYLVKETDSEGYKVKVNSQEVANATVSKTGITSDETLAFEN EEEEECCCEEEECCCCCCCEEHEEECCCCCEEEEECCHHHHCCCHHCCCCCCCCEEEECC NKEPVVPTGVDQKINGYLALIVIAGISLGIWGIHTIRIRKHD CCCCCCCCCCCCHHCCEEEEEEHHHHHCCEEEEEEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11296296 [H]