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The map label for this gene is norM [H]

Identifier: 71909855

GI number: 71909855

Start: 62807

End: 63778

Strand: Direct

Name: norM [H]

Synonym: M5005_Spy_0041

Alternate gene names: 71909855

Gene position: 62807-63778 (Clockwise)

Preceding gene: 161936128

Following gene: 71909856

Centisome position: 3.42

GC content: 40.64

Gene sequence:

>972_bases
ATGATATATAATAATAGAAGAAAAATTTTCTCTTTAGCTCTGCCTTCTATGATAGAAAATATTTTACAGATGTTAATGGG
AATGGTTGATAATTACCTGGTGGCTCAAATTGGACTTGTAGCAGTCTCTGGTGTCTCCATAGCTAACAACATTATCAGTA
TTTATCAGTCCCTCTTTATCGCGCTGGGAGCTGCTGTATCTAGTCTGATTGCTCGAAGTATTGGAGAAAATAATCAGAAC
AAACAATTAAACTATATGGCAGGTGTCTTGCAAGTAACACTCCTCCTTTCGGTCGGCTTAGGGTTGTTATCAGTTGCTGG
ACATCATCAGGTGTTAGAATGGCTAGGAGCTGAAGCTTCTGTAACATTGGTTGGAGGGCAATATCTATCCATTGTCGGCG
GTATGATTGTTAGTCTAGGACTTTTAACTAGCTTAGGAGCTATTGTTCGAGCTCAAGGGTATCCTAAGATTCCTATGCAA
GTGAGCTTATTAATAAACGTACTCAATGCCATTTTTTCTGCCTTGTCTATCTATGTATGGGGATTTGGTCTTCTTGGTGT
TGCTTGGGCGACGGTTTTATCTCGTTTAGTGGGTGTGTTTTTACTTTGTCAGTTTATTCCTATTAAACAGGTTGCGAAAC
GATTGATGAGACCTTTGGACAAAATTATTTTTGATTTATCACTACCTGCTGCTGGTGAACGTTTGATGATGAGAGCAGGA
GATGTCCTAATTATTGGCATTGTTGTTCGCTTTGGGACAACGGCCTTGGCAGGTAATGCTATTGGAGAAACCTTGACTCA
GTTTAATTACATGCCTGGCTTAGCCATGGCAACGGCAACAATTATTCTAGTGGCTAGGCAACTGGGGGGCGGTAAGGTGA
CTGAGATAAGGTATATTATTAGAGAAGCTTTTATTTTATCCACCCTCATGATGCTGGTTATGGGAGCCTTGACCTATTCT
GCTAGGTCCTAG

Upstream 100 bases:

>100_bases
AGACTTTATGAATTCATTAATGGACCAAAATAACTGAATGAGTCCAGTGACTGTGTTTGAAAAAATCGTTTGATCAAGAA
TTTTTTATTAGGGGACATAA

Downstream 100 bases:

>100_bases
TCTCTTGCCGCTATTTACACAGAATACTGATGCTCAAAGGTCTGCCATGATTGTTTTACTTTTTTCTTTACTAGGAGCTC
CCGCAACGGCAGGCACTTTA

Product: Na+ driven multidrug efflux pump

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MIYNNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGVSIANNIISIYQSLFIALGAAVSSLIARSIGENNQN
KQLNYMAGVLQVTLLLSVGLGLLSVAGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQ
VSLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPLDKIIFDLSLPAAGERLMMRAG
DVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMATATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYS
ARS

Sequences:

>Translated_323_residues
MIYNNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGVSIANNIISIYQSLFIALGAAVSSLIARSIGENNQN
KQLNYMAGVLQVTLLLSVGLGLLSVAGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQ
VSLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPLDKIIFDLSLPAAGERLMMRAG
DVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMATATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYS
ARS
>Mature_323_residues
MIYNNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGVSIANNIISIYQSLFIALGAAVSSLIARSIGENNQN
KQLNYMAGVLQVTLLLSVGLGLLSVAGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQ
VSLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPLDKIIFDLSLPAAGERLMMRAG
DVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMATATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYS
ARS

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=332, Percent_Identity=28.0120481927711, Blast_Score=101, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 34589; Mature: 34589

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYNNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGVSIANNIISIYQSLFI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGLGLLSVAGHHQVLEWLGAEAS
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQVSLLINVLNAIFSALSIYVW
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPLDKIIFDLSLPAAGERLMMRAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
DVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMATATIILVARQLGGGKVTEIRYII
CHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
REAFILSTLMMLVMGALTYSARS
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIYNNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGVSIANNIISIYQSLFI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGLGLLSVAGHHQVLEWLGAEAS
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQVSLLINVLNAIFSALSIYVW
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPLDKIIFDLSLPAAGERLMMRAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
DVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMATATIILVARQLGGGKVTEIRYII
CHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
REAFILSTLMMLVMGALTYSARS
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]