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The map label for this gene is infC [H]

Identifier: 71908289

GI number: 71908289

Start: 2872168

End: 2872581

Strand: Reverse

Name: infC [H]

Synonym: Daro_2676

Alternate gene names: 71908289

Gene position: 2872581-2872168 (Counterclockwise)

Preceding gene: 71908290

Following gene: 71908288

Centisome position: 63.82

GC content: 54.83

Gene sequence:

>414_bases
ATGGCTGAAGAAGCCGGTGTCGATCTGGTTGAGATTGCACCGACTGCAAAGCCGCCGGTCTGCCGCATCATGGACTACGG
CAAGTTCAAGTATCAGGAACAAAAGCGTGCGCATGAGGCCAAGCTGAAGCAGAAACAGGTGCAGGTTAAGGAAATCAAAC
TGCGCCCGGGTACCGACGAAAACGATTACCAGATCAAGCTCAGGAATATGACGCGTTTCCTGGAAGAGGGCGACAAGGTC
AAAGTGACTCTGCGCTTCCGGGGGCGTGAAATGGCGCATCAGGAATTCGGCATGCGCCAGTTGGAACGAATCAAGGCAGA
CCTCGACGCCGTTGGTGCGGTTGAGCAGATGCCGAAGATGGAAGGTCGTCAGATGATCATGATCATCGGGCCGGCCAAGA
AGAAGCAAGCGTAG

Upstream 100 bases:

>100_bases
GGCGCATCGCCTCAACGAAGAAATCACGGTTCCTGAGATTCGTCTCCAGGGTGCAGAAGGTGAACAGCTAGGCATCGTCA
ACATTCGTGCCGCGCTGCAA

Downstream 100 bases:

>100_bases
TAAATCAGTTGTTATTAGTGCTTTCGGGTAGTAAAAGCGTTCCCGCCGGGAATCACCTGACGGCATGTCATTAAGGAGCA
TCTAAATGCCCAAAATGAAG

Product: translation initiation factor 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MAEEAGVDLVEIAPTAKPPVCRIMDYGKFKYQEQKRAHEAKLKQKQVQVKEIKLRPGTDENDYQIKLRNMTRFLEEGDKV
KVTLRFRGREMAHQEFGMRQLERIKADLDAVGAVEQMPKMEGRQMIMIIGPAKKKQA

Sequences:

>Translated_137_residues
MAEEAGVDLVEIAPTAKPPVCRIMDYGKFKYQEQKRAHEAKLKQKQVQVKEIKLRPGTDENDYQIKLRNMTRFLEEGDKV
KVTLRFRGREMAHQEFGMRQLERIKADLDAVGAVEQMPKMEGRQMIMIIGPAKKKQA
>Mature_136_residues
AEEAGVDLVEIAPTAKPPVCRIMDYGKFKYQEQKRAHEAKLKQKQVQVKEIKLRPGTDENDYQIKLRNMTRFLEEGDKVK
VTLRFRGREMAHQEFGMRQLERIKADLDAVGAVEQMPKMEGRQMIMIIGPAKKKQA

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=135, Percent_Identity=68.1481481481482, Blast_Score=179, Evalue=6e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 15859; Mature: 15728

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEEAGVDLVEIAPTAKPPVCRIMDYGKFKYQEQKRAHEAKLKQKQVQVKEIKLRPGTDE
CCCCCCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCC
NDYQIKLRNMTRFLEEGDKVKVTLRFRGREMAHQEFGMRQLERIKADLDAVGAVEQMPKM
CCEEEEHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EGRQMIMIIGPAKKKQA
CCCEEEEEECCCCCCCC
>Mature Secondary Structure 
AEEAGVDLVEIAPTAKPPVCRIMDYGKFKYQEQKRAHEAKLKQKQVQVKEIKLRPGTDE
CCCCCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCC
NDYQIKLRNMTRFLEEGDKVKVTLRFRGREMAHQEFGMRQLERIKADLDAVGAVEQMPKM
CCEEEEHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EGRQMIMIIGPAKKKQA
CCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA