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The map label for this gene is trpS [H]

Identifier: 71908077

GI number: 71908077

Start: 2659191

End: 2660393

Strand: Reverse

Name: trpS [H]

Synonym: Daro_2459

Alternate gene names: 71908077

Gene position: 2660393-2659191 (Counterclockwise)

Preceding gene: 71908078

Following gene: 71908076

Centisome position: 59.11

GC content: 58.85

Gene sequence:

>1203_bases
ATGTACGCAGAACGTGTTCTCTCCGGCATGCGCCCAACCGGGTCGCTGCACCTTGGCCACTATCACGGTGTTCTCAAGAA
CTGGGTCAAGCTCCAGCATGAATACCCCTGCTTGTTTTTTGTGGCTGACTGGCATGCGCTGACCACCCAATACGACAATC
CGCAGGGGATCGAAAAGTCCTCGATGGACATGGTCATCGACTGGCTGGCGGCTGGTGTCGATCCGAATCAGGCGACGCTG
TTCATCCAGTCCAAGGTGCCGGAGCATGCCGAACTGCACCTGCTGATGTCGATGATGACGCCGCTCAGCTGGCTGGAGCG
GGTGCCGACCTACAAGGACCAGCAGGAAAAGCTGGCAGGCAAGGACCTGACAACCTACGGCTTCCTCGGCTACCCGCTGC
TGATGAGCGCCGACATCCTGATCTATCGTGCCGACAAGGTGCCGGTTGGCGAAGACCAGATTCCGCACGTTGAATTCACC
CGGGAGCTGGCCCGCCGCTTCAATCATATGTATGGCCGTGAGCCGGGTTTCGAAGACAAGGCTCGCGAGGCCGTCAAGAA
GCTGGGCAGCAAGAAGGCACGTTTGTATGAAGAGTTGCGCACCCGTTTTCAGCAGAACGGCGACAAGGAAGCCGTCGAGC
AGGCCAAGGCCATGCTCAACGAAATTCAGCACATGTCGGCGATCGACCGTGAGCGCCTGTTCGGTTTCCTCGAAGGCACG
GGCAAGATGATCCTGGTTGAACCCGGTTACCTGCTGACCGAGGAATCCAAAATGCCCGGCCTGGATGGGCAGAAGATGTC
CAAGTCATATCACAACACCATCACCATGCGCGAATCCGAGGAATCGGTGGCCAAGAAGGTGAAGAGCATGCCGACCGACA
CCAATCGCGTGCGTCGCACCGATCCGGGTGATCCGGCACGTTGCCCGGTCTGGCAGCTGCATCAGGTCTATTCCGACGAC
AGCACCAAGGAATGGGTGCAGCAGGGTTGCAAGACCGCCGGCATCGGTTGCATCGAGTGCAAGCAACCGGTCATTGATGG
CATCCTGAAAGAGCAGGTGCCGATGCGGGAGCGGGCGCAGGTCTATCTGGACGATCCGACGCTGGTCAAGAACATCATTG
CCGACGGCTGCGAGAAGGCTCGTGAATACGCCCGTGAAACGATGCGCGATGTCCGCGAGTCGATGGGGCTGGAATACCAC
TGA

Upstream 100 bases:

>100_bases
CTCCTGTTATTCACCGGTATCCTCGGTGCTGTCATGAACCCGCTGGTTGTTTTGTCAGCCCGGGCGATCGAGTTAATTTT
TGGTCTTTACTAAATAATCT

Downstream 100 bases:

>100_bases
TGTTCGGTTATGACTGGGAAGCGCTGATCTGGATCGGTATTGGCTTTGGCGGCCAGGCGCTGTTCATGATGCGCTTCGTT
ATCCAGTGGTGGAGCAGTGA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MYAERVLSGMRPTGSLHLGHYHGVLKNWVKLQHEYPCLFFVADWHALTTQYDNPQGIEKSSMDMVIDWLAAGVDPNQATL
FIQSKVPEHAELHLLMSMMTPLSWLERVPTYKDQQEKLAGKDLTTYGFLGYPLLMSADILIYRADKVPVGEDQIPHVEFT
RELARRFNHMYGREPGFEDKAREAVKKLGSKKARLYEELRTRFQQNGDKEAVEQAKAMLNEIQHMSAIDRERLFGFLEGT
GKMILVEPGYLLTEESKMPGLDGQKMSKSYHNTITMRESEESVAKKVKSMPTDTNRVRRTDPGDPARCPVWQLHQVYSDD
STKEWVQQGCKTAGIGCIECKQPVIDGILKEQVPMRERAQVYLDDPTLVKNIIADGCEKAREYARETMRDVRESMGLEYH

Sequences:

>Translated_400_residues
MYAERVLSGMRPTGSLHLGHYHGVLKNWVKLQHEYPCLFFVADWHALTTQYDNPQGIEKSSMDMVIDWLAAGVDPNQATL
FIQSKVPEHAELHLLMSMMTPLSWLERVPTYKDQQEKLAGKDLTTYGFLGYPLLMSADILIYRADKVPVGEDQIPHVEFT
RELARRFNHMYGREPGFEDKAREAVKKLGSKKARLYEELRTRFQQNGDKEAVEQAKAMLNEIQHMSAIDRERLFGFLEGT
GKMILVEPGYLLTEESKMPGLDGQKMSKSYHNTITMRESEESVAKKVKSMPTDTNRVRRTDPGDPARCPVWQLHQVYSDD
STKEWVQQGCKTAGIGCIECKQPVIDGILKEQVPMRERAQVYLDDPTLVKNIIADGCEKAREYARETMRDVRESMGLEYH
>Mature_400_residues
MYAERVLSGMRPTGSLHLGHYHGVLKNWVKLQHEYPCLFFVADWHALTTQYDNPQGIEKSSMDMVIDWLAAGVDPNQATL
FIQSKVPEHAELHLLMSMMTPLSWLERVPTYKDQQEKLAGKDLTTYGFLGYPLLMSADILIYRADKVPVGEDQIPHVEFT
RELARRFNHMYGREPGFEDKAREAVKKLGSKKARLYEELRTRFQQNGDKEAVEQAKAMLNEIQHMSAIDRERLFGFLEGT
GKMILVEPGYLLTEESKMPGLDGQKMSKSYHNTITMRESEESVAKKVKSMPTDTNRVRRTDPGDPARCPVWQLHQVYSDD
STKEWVQQGCKTAGIGCIECKQPVIDGILKEQVPMRERAQVYLDDPTLVKNIIADGCEKAREYARETMRDVRESMGLEYH

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=170, Percent_Identity=42.9411764705882, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI41352700, Length=170, Percent_Identity=42.9411764705882, Blast_Score=140, Evalue=3e-33,
Organism=Escherichia coli, GI1789786, Length=167, Percent_Identity=41.9161676646707, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71982800, Length=172, Percent_Identity=35.4651162790698, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71982793, Length=172, Percent_Identity=35.4651162790698, Blast_Score=115, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6320474, Length=184, Percent_Identity=36.9565217391304, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24666151, Length=172, Percent_Identity=38.953488372093, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 45877; Mature: 45877

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAERVLSGMRPTGSLHLGHYHGVLKNWVKLQHEYPCLFFVADWHALTTQYDNPQGIEKS
CCHHHHHHCCCCCCCEECHHHHHHHHHHHHHHCCCCEEEEEECHHHHHCCCCCCCCCCHH
SMDMVIDWLAAGVDPNQATLFIQSKVPEHAELHLLMSMMTPLSWLERVPTYKDQQEKLAG
HHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCC
KDLTTYGFLGYPLLMSADILIYRADKVPVGEDQIPHVEFTRELARRFNHMYGREPGFEDK
CCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHH
AREAVKKLGSKKARLYEELRTRFQQNGDKEAVEQAKAMLNEIQHMSAIDRERLFGFLEGT
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GKMILVEPGYLLTEESKMPGLDGQKMSKSYHNTITMRESEESVAKKVKSMPTDTNRVRRT
CCEEEECCCEEEECCCCCCCCCHHHHHHHHHCEEEEECCHHHHHHHHHHCCCCCCCCCCC
DPGDPARCPVWQLHQVYSDDSTKEWVQQGCKTAGIGCIECKQPVIDGILKEQVPMRERAQ
CCCCCCCCCHHHHHHHHCCCCHHHHHHHCHHHCCCCHHHCCHHHHHHHHHHCCCCHHCCE
VYLDDPTLVKNIIADGCEKAREYARETMRDVRESMGLEYH
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MYAERVLSGMRPTGSLHLGHYHGVLKNWVKLQHEYPCLFFVADWHALTTQYDNPQGIEKS
CCHHHHHHCCCCCCCEECHHHHHHHHHHHHHHCCCCEEEEEECHHHHHCCCCCCCCCCHH
SMDMVIDWLAAGVDPNQATLFIQSKVPEHAELHLLMSMMTPLSWLERVPTYKDQQEKLAG
HHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCC
KDLTTYGFLGYPLLMSADILIYRADKVPVGEDQIPHVEFTRELARRFNHMYGREPGFEDK
CCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHH
AREAVKKLGSKKARLYEELRTRFQQNGDKEAVEQAKAMLNEIQHMSAIDRERLFGFLEGT
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GKMILVEPGYLLTEESKMPGLDGQKMSKSYHNTITMRESEESVAKKVKSMPTDTNRVRRT
CCEEEECCCEEEECCCCCCCCCHHHHHHHHHCEEEEECCHHHHHHHHHHCCCCCCCCCCC
DPGDPARCPVWQLHQVYSDDSTKEWVQQGCKTAGIGCIECKQPVIDGILKEQVPMRERAQ
CCCCCCCCCHHHHHHHHCCCCHHHHHHHCHHHCCCCHHHCCHHHHHHHHHHCCCCHHCCE
VYLDDPTLVKNIIADGCEKAREYARETMRDVRESMGLEYH
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]