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The map label for this gene is slyD [H]

Identifier: 71907968

GI number: 71907968

Start: 2531318

End: 2531818

Strand: Reverse

Name: slyD [H]

Synonym: Daro_2349

Alternate gene names: 71907968

Gene position: 2531818-2531318 (Counterclockwise)

Preceding gene: 161377473

Following gene: 71907963

Centisome position: 56.25

GC content: 56.89

Gene sequence:

>501_bases
ATGAACATGCAAGTCGCCAAGAATACCGTCGTTACCCTCGACTACCACGTCACCGATCCGGATGGCGAAGTGGTCGATGA
AGGCCGTGAGCCGTTGGTCTACCTGCATGGTGGTTATGAAGACATCTTCCCGAAAATCGAAGAAGCCATGCAGGGCAAGA
AGATTGGCGAATCGATCCAGGTCAAGCTGCAGCCCGACGAAGCCTTTGGTGACTACGATGCCGAGATGGTGCAGATCGAG
CCGCGCAAGGATTTTCCGAAGGAACTCCAGGTTGGCATGCAGTTCGAAGGCGGTCCGGAAGATGGCGGCGAGGATGACTT
CATCATCTATCGCGTCACCGATATCGCCGACGACAAGGTCGTCCTCGACGGCAATCACCCCTTGGCCGGCATGGCACTGG
TGTTCACCTGCACGGTGACGTCGATTCGCCCGGCTAGCGAGGAAGAAGTCGAACACGGTCACGTCCATCACCCGGATGAA
GATGGCGAAACCTGCCACTGA

Upstream 100 bases:

>100_bases
GGTAGAATTCGCCAATCTGGCGGACTCAGGATGTGCCACGTGCTGGCGGCAATATCCGTAGTTTGCTGAAAAAGCCCATC
AATACTAGGAATGCCACAGA

Downstream 100 bases:

>100_bases
TTCCGGTTTCAGCCGGATGGAAAGATACCCGCTGCGGCGGGTATTTTTTTGCCCCCGATTTATTGTGCTTCCTGCTGTGC
TGCGTCAATCCGGCTTTGGC

Product: peptidylprolyl isomerase, FKBP-type

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MNMQVAKNTVVTLDYHVTDPDGEVVDEGREPLVYLHGGYEDIFPKIEEAMQGKKIGESIQVKLQPDEAFGDYDAEMVQIE
PRKDFPKELQVGMQFEGGPEDGGEDDFIIYRVTDIADDKVVLDGNHPLAGMALVFTCTVTSIRPASEEEVEHGHVHHPDE
DGETCH

Sequences:

>Translated_166_residues
MNMQVAKNTVVTLDYHVTDPDGEVVDEGREPLVYLHGGYEDIFPKIEEAMQGKKIGESIQVKLQPDEAFGDYDAEMVQIE
PRKDFPKELQVGMQFEGGPEDGGEDDFIIYRVTDIADDKVVLDGNHPLAGMALVFTCTVTSIRPASEEEVEHGHVHHPDE
DGETCH
>Mature_166_residues
MNMQVAKNTVVTLDYHVTDPDGEVVDEGREPLVYLHGGYEDIFPKIEEAMQGKKIGESIQVKLQPDEAFGDYDAEMVQIE
PRKDFPKELQVGMQFEGGPEDGGEDDFIIYRVTDIADDKVVLDGNHPLAGMALVFTCTVTSIRPASEEEVEHGHVHHPDE
DGETCH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=153, Percent_Identity=40.5228758169935, Blast_Score=98, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 18483; Mature: 18483

Theoretical pI: Translated: 4.06; Mature: 4.06

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMQVAKNTVVTLDYHVTDPDGEVVDEGREPLVYLHGGYEDIFPKIEEAMQGKKIGESIQ
CCCEECCCEEEEEEEEEECCCCHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCEEE
VKLQPDEAFGDYDAEMVQIEPRKDFPKELQVGMQFEGGPEDGGEDDFIIYRVTDIADDKV
EEECCCCCCCCCCCEEEEEECCCCCCCHHHCCEEECCCCCCCCCCCEEEEEEECCCCCEE
VLDGNHPLAGMALVFTCTVTSIRPASEEEVEHGHVHHPDEDGETCH
EEECCCCHHHEEEEEEEEECCCCCCCHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNMQVAKNTVVTLDYHVTDPDGEVVDEGREPLVYLHGGYEDIFPKIEEAMQGKKIGESIQ
CCCEECCCEEEEEEEEEECCCCHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCEEE
VKLQPDEAFGDYDAEMVQIEPRKDFPKELQVGMQFEGGPEDGGEDDFIIYRVTDIADDKV
EEECCCCCCCCCCCEEEEEECCCCCCCHHHCCEEECCCCCCCCCCCEEEEEEECCCCCEE
VLDGNHPLAGMALVFTCTVTSIRPASEEEVEHGHVHHPDEDGETCH
EEECCCCHHHEEEEEEEEECCCCCCCHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]