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The map label for this gene is intZ [H]

Identifier: 71907955

GI number: 71907955

Start: 2517136

End: 2518416

Strand: Reverse

Name: intZ [H]

Synonym: Daro_2336

Alternate gene names: 71907955

Gene position: 2518416-2517136 (Counterclockwise)

Preceding gene: 71907956

Following gene: 71907954

Centisome position: 55.95

GC content: 56.91

Gene sequence:

>1281_bases
ATGCTCACTGACATGCAGTTGAGGGCTTTGAAGCCCACAGGGCAGATTTATAAGGTTGCTGACCAGCAGGGCCTCTATGT
CGCAGTTACGCGGACAGGGGTTGTCAGTTTCCGGTTCGATTACCGGGTAAACGGGCGCCGTGAGACCCTGGTGATAGGCA
AGTACGACCCGACAGTCGGGACCAAGAAGCCACGCGAACTGGACGGGTTGGATTACGGCATGTCCGTGTCTCTGGCCGAG
GCGCGTTTACTGCTGACACGGGCGCACAGATCCGTCGAGCAGGGAGAGAGCCCCTCGCGTTCCAAGGTTGAGAAGCGGAC
CGAAGCTGCTGACGCGCTAACGTTCGGTAGCTGGGCAGAAAAGTACTTTGCCGAGGCTGATCTGGCTGAGTCCACAAAGG
CCATGCGTAAGTCGGTCTACGATCGCAACTTGGCAGACGAGTTTGGCCGACTGAAGCTGGAAGAAATCACCCCGGTGCGT
CTGATGGCCCGATGCGAGAAAATCAAAGAGCGTGGCGCGGCGGCGCCGGCAGTACATGCTCGCGAGATCGTGTTGCAGGT
ATTTCGCTTCATTCAGGCCCGCGGATTAAAGATCGACAACCCTGCTGAGTCGATTCGACCCAGTGCCATTGCCACATTCA
AGGCCCGCGACAGAGCACTGATGCCGGCCGAGATTCATACTTTTTTTAAAGCGCTTGAGCAGACTGCAACGGCGGCCACG
CTGCGCTTGGCAGTCAAGTTCATGTTGCTGACAATGGTGCGCAAGACGGAGTTCATCGAGGCTAAATGGGACGAGGTTAA
CTTCGAGACTGCAATCTGGACGATCCCCAAGGAACGTATGAAAGCAGGGCGCCCGCATAATGTTTACCTGAGCCAGCAGG
CGCTCGATATCCTGGTGGCCTTCAAAACTTGCTTTAGTGCTAGTTCGTACCTGCATCCTGGGCGGTACGAGACCGCGCTT
CCTATCAGTTCGGCCACGCTGAATCGGGTGATCGACGCCACCGTGAAAGTGATTCACGATCGAGGGGAGGAGTTTGCCCC
CTTCACCGTGCATGACTTGCGCCGTACGGCTAGCACGCTACTGCATGAGGCTGGTTTTAACACTGACTGGATCGAGAAGT
GTCTTGCGCATGAGCAGCGCGGTGTGCGTGCTATCTACAACAAGGCTGAGTACGCCGAGCAGCGCCGAACCATGCTTCAG
GCCTGGGCTGACATGTTGGATGCCTGGATCAAAAATAGCGCCAGCGTGGTGCCCATTAGACGCAGTGCTGGCGTTGCTTG
A

Upstream 100 bases:

>100_bases
ATTGCTGACGGTATAGAGATCTGGTCCTTGAACGACCCAAGTTGATACCGTCAAATGCTCTGACGGTATCGGATGACGGT
ATCAGTTTAAGGAGGATCAG

Downstream 100 bases:

>100_bases
GGTATGGATATGGTCCGTCCGAAATATATCTACAATTTTCGGACATCACTTCTTGCAAATTGTCCGAAAAAATTATACAA
ATATCGGACAAGGAACCCCA

Product: Phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MLTDMQLRALKPTGQIYKVADQQGLYVAVTRTGVVSFRFDYRVNGRRETLVIGKYDPTVGTKKPRELDGLDYGMSVSLAE
ARLLLTRAHRSVEQGESPSRSKVEKRTEAADALTFGSWAEKYFAEADLAESTKAMRKSVYDRNLADEFGRLKLEEITPVR
LMARCEKIKERGAAAPAVHAREIVLQVFRFIQARGLKIDNPAESIRPSAIATFKARDRALMPAEIHTFFKALEQTATAAT
LRLAVKFMLLTMVRKTEFIEAKWDEVNFETAIWTIPKERMKAGRPHNVYLSQQALDILVAFKTCFSASSYLHPGRYETAL
PISSATLNRVIDATVKVIHDRGEEFAPFTVHDLRRTASTLLHEAGFNTDWIEKCLAHEQRGVRAIYNKAEYAEQRRTMLQ
AWADMLDAWIKNSASVVPIRRSAGVA

Sequences:

>Translated_426_residues
MLTDMQLRALKPTGQIYKVADQQGLYVAVTRTGVVSFRFDYRVNGRRETLVIGKYDPTVGTKKPRELDGLDYGMSVSLAE
ARLLLTRAHRSVEQGESPSRSKVEKRTEAADALTFGSWAEKYFAEADLAESTKAMRKSVYDRNLADEFGRLKLEEITPVR
LMARCEKIKERGAAAPAVHAREIVLQVFRFIQARGLKIDNPAESIRPSAIATFKARDRALMPAEIHTFFKALEQTATAAT
LRLAVKFMLLTMVRKTEFIEAKWDEVNFETAIWTIPKERMKAGRPHNVYLSQQALDILVAFKTCFSASSYLHPGRYETAL
PISSATLNRVIDATVKVIHDRGEEFAPFTVHDLRRTASTLLHEAGFNTDWIEKCLAHEQRGVRAIYNKAEYAEQRRTMLQ
AWADMLDAWIKNSASVVPIRRSAGVA
>Mature_426_residues
MLTDMQLRALKPTGQIYKVADQQGLYVAVTRTGVVSFRFDYRVNGRRETLVIGKYDPTVGTKKPRELDGLDYGMSVSLAE
ARLLLTRAHRSVEQGESPSRSKVEKRTEAADALTFGSWAEKYFAEADLAESTKAMRKSVYDRNLADEFGRLKLEEITPVR
LMARCEKIKERGAAAPAVHAREIVLQVFRFIQARGLKIDNPAESIRPSAIATFKARDRALMPAEIHTFFKALEQTATAAT
LRLAVKFMLLTMVRKTEFIEAKWDEVNFETAIWTIPKERMKAGRPHNVYLSQQALDILVAFKTCFSASSYLHPGRYETAL
PISSATLNRVIDATVKVIHDRGEEFAPFTVHDLRRTASTLLHEAGFNTDWIEKCLAHEQRGVRAIYNKAEYAEQRRTMLQ
AWADMLDAWIKNSASVVPIRRSAGVA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=417, Percent_Identity=31.4148681055156, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788690, Length=410, Percent_Identity=28.5365853658537, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1788974, Length=422, Percent_Identity=27.9620853080569, Blast_Score=146, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 48117; Mature: 48117

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDMQLRALKPTGQIYKVADQQGLYVAVTRTGVVSFRFDYRVNGRRETLVIGKYDPTVG
CCCCCCCEEECCCCCEEEEECCCCEEEEEEECCEEEEEEEEEECCCEEEEEEECCCCCCC
TKKPRELDGLDYGMSVSLAEARLLLTRAHRSVEQGESPSRSKVEKRTEAADALTFGSWAE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
KYFAEADLAESTKAMRKSVYDRNLADEFGRLKLEEITPVRLMARCEKIKERGAAAPAVHA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEHHHCCHHHHHHHHHHHHHCCCCCCHHHH
REIVLQVFRFIQARGLKIDNPAESIRPSAIATFKARDRALMPAEIHTFFKALEQTATAAT
HHHHHHHHHHHHHCCCCCCCCHHHCCCCCEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHH
LRLAVKFMLLTMVRKTEFIEAKWDEVNFETAIWTIPKERMKAGRPHNVYLSQQALDILVA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHCCCCCEEEEHHHHHHHHHH
FKTCFSASSYLHPGRYETALPISSATLNRVIDATVKVIHDRGEEFAPFTVHDLRRTASTL
HHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LHEAGFNTDWIEKCLAHEQRGVRAIYNKAEYAEQRRTMLQAWADMLDAWIKNSASVVPIR
HHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEH
RSAGVA
HCCCCC
>Mature Secondary Structure
MLTDMQLRALKPTGQIYKVADQQGLYVAVTRTGVVSFRFDYRVNGRRETLVIGKYDPTVG
CCCCCCCEEECCCCCEEEEECCCCEEEEEEECCEEEEEEEEEECCCEEEEEEECCCCCCC
TKKPRELDGLDYGMSVSLAEARLLLTRAHRSVEQGESPSRSKVEKRTEAADALTFGSWAE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
KYFAEADLAESTKAMRKSVYDRNLADEFGRLKLEEITPVRLMARCEKIKERGAAAPAVHA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEHHHCCHHHHHHHHHHHHHCCCCCCHHHH
REIVLQVFRFIQARGLKIDNPAESIRPSAIATFKARDRALMPAEIHTFFKALEQTATAAT
HHHHHHHHHHHHHCCCCCCCCHHHCCCCCEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHH
LRLAVKFMLLTMVRKTEFIEAKWDEVNFETAIWTIPKERMKAGRPHNVYLSQQALDILVA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHCCCCCEEEEHHHHHHHHHH
FKTCFSASSYLHPGRYETALPISSATLNRVIDATVKVIHDRGEEFAPFTVHDLRRTASTL
HHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LHEAGFNTDWIEKCLAHEQRGVRAIYNKAEYAEQRRTMLQAWADMLDAWIKNSASVVPIR
HHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEH
RSAGVA
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]