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The map label for this gene is ycfH [C]

Identifier: 71907816

GI number: 71907816

Start: 2370608

End: 2371381

Strand: Reverse

Name: ycfH [C]

Synonym: Daro_2194

Alternate gene names: 71907816

Gene position: 2371381-2370608 (Counterclockwise)

Preceding gene: 71907817

Following gene: 71907815

Centisome position: 52.68

GC content: 55.04

Gene sequence:

>774_bases
ATGCTGGTCGACTCCCACTGCCATCTCGATTTTCCTGATCTGGCCAATCGCCTGCCTGATGTGCTTCGGCACATGCAGGA
CAACCAGGTTGGGTTGGCCGTCTGCATCGGCGTCAATCTGGAAGATTTTCCCAAGGTTCTCGCGCTGGCCGAACATGAGC
CACGCCTGTTCGCTACCGTGGGGGTACATCCGGAATATACGGATGTCGAAGAGCCTGATGAAAATCGCCTTGTCGAGCTT
GCCTCGCACCCGAAGGTCATCGCCATCGGCGAAACCGGGCTCGACTACTATTGGCAAAAAGACCAGCCAGAGTGGCAACG
CGATCGTTTTCGCACGCATATTCGTGCGGCAAAACGTTGCGACAAGCCGCTGGTTGTGCATACCCGCGATTCCGCTCTCG
ATACGCTTATGCTGCTGAAGGAAGAGGGAGCTGATGCAGTCGGTGGTGTGATGCATTGTTTTACCGAAAACTGGGACATG
GCCAGGCAAGCACTTGATCTCGGCTTCTATATCTCGTTTTCGGGCATTGTTACATTCAAGAACGCCGCCATCGTCAAGGA
AGTGGCTCAAAAATGCCCGCTTGATCGCATTCTCGTCGAAACCGATTCTCCGTACCTGGCCCCGGTGCCGTACCGGGGAA
AGCCTAACGAACCGGCCTATGTTCGTTATGTCGCTGAAGAAATTGCTCGCCTGCGCGGGCTCTCATTTGAAGAGCTTGCC
GCCGCGACGACGAATAATTTTTTCCGCTTGTTCAAACACGCTTGCCGCCCGTGA

Upstream 100 bases:

>100_bases
CAATGACGAAAGCGGTCAGGAAGCGCGGCGCAAGATCGAAGGCCTGCTCGGCGGTGTCATGCAATCTGCACGGCCGACGC
ACACGCTCTGATCAGCCATC

Downstream 100 bases:

>100_bases
AAACCATGAAAAAAACCTTGTTGACCGCTGTCTTTGCGCTGGCCTTTCCCGTGCTGGCCTGCGCTGCGACCTATGATGAT
TTGATCAACTCTGCAAAGAT

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLVDSHCHLDFPDLANRLPDVLRHMQDNQVGLAVCIGVNLEDFPKVLALAEHEPRLFATVGVHPEYTDVEEPDENRLVEL
ASHPKVIAIGETGLDYYWQKDQPEWQRDRFRTHIRAAKRCDKPLVVHTRDSALDTLMLLKEEGADAVGGVMHCFTENWDM
ARQALDLGFYISFSGIVTFKNAAIVKEVAQKCPLDRILVETDSPYLAPVPYRGKPNEPAYVRYVAEEIARLRGLSFEELA
AATTNNFFRLFKHACRP

Sequences:

>Translated_257_residues
MLVDSHCHLDFPDLANRLPDVLRHMQDNQVGLAVCIGVNLEDFPKVLALAEHEPRLFATVGVHPEYTDVEEPDENRLVEL
ASHPKVIAIGETGLDYYWQKDQPEWQRDRFRTHIRAAKRCDKPLVVHTRDSALDTLMLLKEEGADAVGGVMHCFTENWDM
ARQALDLGFYISFSGIVTFKNAAIVKEVAQKCPLDRILVETDSPYLAPVPYRGKPNEPAYVRYVAEEIARLRGLSFEELA
AATTNNFFRLFKHACRP
>Mature_257_residues
MLVDSHCHLDFPDLANRLPDVLRHMQDNQVGLAVCIGVNLEDFPKVLALAEHEPRLFATVGVHPEYTDVEEPDENRLVEL
ASHPKVIAIGETGLDYYWQKDQPEWQRDRFRTHIRAAKRCDKPLVVHTRDSALDTLMLLKEEGADAVGGVMHCFTENWDM
ARQALDLGFYISFSGIVTFKNAAIVKEVAQKCPLDRILVETDSPYLAPVPYRGKPNEPAYVRYVAEEIARLRGLSFEELA
AATTNNFFRLFKHACRP

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=268, Percent_Identity=32.8358208955224, Blast_Score=114, Evalue=6e-26,
Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=32.5842696629214, Blast_Score=114, Evalue=7e-26,
Organism=Homo sapiens, GI226061853, Length=271, Percent_Identity=30.9963099630996, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI226061614, Length=257, Percent_Identity=32.6848249027237, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI14042943, Length=292, Percent_Identity=28.4246575342466, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI225903424, Length=274, Percent_Identity=28.8321167883212, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI226061595, Length=228, Percent_Identity=29.8245614035088, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI225903439, Length=247, Percent_Identity=28.7449392712551, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1787342, Length=255, Percent_Identity=47.4509803921569, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI87082439, Length=254, Percent_Identity=31.8897637795276, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI48994985, Length=257, Percent_Identity=32.295719844358, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17559024, Length=279, Percent_Identity=26.8817204301075, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=27.0992366412214, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=301, Percent_Identity=28.9036544850498, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17565396, Length=304, Percent_Identity=25.6578947368421, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648690, Length=283, Percent_Identity=28.9752650176678, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24586117, Length=250, Percent_Identity=31.2, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI221330018, Length=250, Percent_Identity=31.2, Blast_Score=84, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29201; Mature: 29201

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVDSHCHLDFPDLANRLPDVLRHMQDNQVGLAVCIGVNLEDFPKVLALAEHEPRLFATV
CEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCCEEEEEE
GVHPEYTDVEEPDENRLVELASHPKVIAIGETGLDYYWQKDQPEWQRDRFRTHIRAAKRC
CCCCCCCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
DKPLVVHTRDSALDTLMLLKEEGADAVGGVMHCFTENWDMARQALDLGFYISFSGIVTFK
CCCEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCEEEEECCEEEEC
NAAIVKEVAQKCPLDRILVETDSPYLAPVPYRGKPNEPAYVRYVAEEIARLRGLSFEELA
HHHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHH
AATTNNFFRLFKHACRP
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLVDSHCHLDFPDLANRLPDVLRHMQDNQVGLAVCIGVNLEDFPKVLALAEHEPRLFATV
CEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCCEEEEEE
GVHPEYTDVEEPDENRLVELASHPKVIAIGETGLDYYWQKDQPEWQRDRFRTHIRAAKRC
CCCCCCCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
DKPLVVHTRDSALDTLMLLKEEGADAVGGVMHCFTENWDMARQALDLGFYISFSGIVTFK
CCCEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCEEEEECCEEEEC
NAAIVKEVAQKCPLDRILVETDSPYLAPVPYRGKPNEPAYVRYVAEEIARLRGLSFEELA
HHHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHH
AATTNNFFRLFKHACRP
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]