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The map label for this gene is dctB [H]

Identifier: 71907773

GI number: 71907773

Start: 2319059

End: 2320834

Strand: Reverse

Name: dctB [H]

Synonym: Daro_2150

Alternate gene names: 71907773

Gene position: 2320834-2319059 (Counterclockwise)

Preceding gene: 71907774

Following gene: 71907772

Centisome position: 51.56

GC content: 65.77

Gene sequence:

>1776_bases
ATGCTCGGGGCGGCGGTCGCTTTTTGCCTGCTGCTCGGCTGGCTGGCCTACCGTACCTTGTTCGCCGTCACCCTAGATAA
TGAGCGACGACTGGCTGCGCAGCGCCTTGATGCCTTCGCGTTATCGCTGGAAGCCACGCTGTCGCGGCACGAATCCTTGC
CTGGCCTGCTGGCGCTGGATCCTTCGCTGGCCGCCGTGCTCGGTGAGCCGGACAGCCAGCCGCGGATTGCCGCCGCCAAT
GCCTATCTCGAAGCGGCCCAGCAGGGGGCCAACGTGGCGGTCACGTTCCTGATCGATGCGCAGGGCAAGACGGTGGCCGC
CAGCAACTGGCGCCTGCCGCGCAGCTTTGTCGGCCACAACTACGCGTTTCGCCCGTATTTTCGCGATGCGCTGGCCAATG
GCCTTGGTCGTTTCTACGGTGTTGGTGTCACTACTGGTGAGCCCGGTTATTTTCTTGCAGCGCCGGTGCGCGAGCAGGGC
AGGGTGCTCGGCGTGATCGTCCTCAAGGTCGGGCTGGAGAGCATGGAGCAGGCCCTGGCCAATGCCGGCGATACCCTGCT
GCTGGCCGATGCCGATGGCGTCGTCTTTTTGTCATCCGACCGCCAGTTGCGCTATCGGTCGCTGGCACCACTCGGCGATG
CGGTCCAAGCCCGGCTGGCTGAAACACAGCAATACGGTATGCAGCACATCACGCCGTTGGCCGACCAGCCGTTGATGCTC
ACCGCGACGCAGCCGGTGCGCCTTGCCTTGTCTGGTGAAGCGCCGCGCGAACGGCTGATCCACGCTCGCCCGGTTGGTCA
CTCCGGCTGGCAGGTCGTGCAGCTTGGCGACCCCGGCGAGGCCCGGGCCACCGCCCTTGGGGCCGCGGCGGCGGTGGCCT
TTGCGGCTGCCTTTACCCTCGGTCTGGCCGCCCATTTCCGCCACCGGGCCCGCCGTCGCGACGAGCTGCGCCGCGTCTAT
GACGAACTGGAAAACCGCATTGCCGAGCGTACGGCCGATTTGACCGAGCAGATCGCTGCCCTCGAAAGCACCAAGGCCAT
CCTGCGCGAAACCCGCGATGCTGCGGTGCAGGCCGGCAAGCTGGCGACGCTGGGCCAGATGTCGGCCGGCATCAGCCACG
AACTGAACCAGCCACTGGCCGCGTTGCAAACCTTTGCCGACAACGCCTCTGCCTTGCTGGCGCGCGGTCGTTACGAAGAG
GTCGCCGAAAACCTGCAAATGATCAGCGAACTGGTCGATCGAACCGGGCGCATCGTTCGGCAGCTCAAGACCTTTGCCCG
CAAGGAAGCGCCGACGCCGCAGGCGGTGACGGTGGCCAGCGCCATCGAGCATGCGCTGATGATCGTCGAGCCGCGTCGCC
GCGAAATCGGTGCCCATATTGTCGTCGAGCCGCAATCGGCTGCACTGCTGGTCATCGCCGAGGCAGGCCGGCTGGAACAG
GTTCTGGTCAACCTGCTGCGTAACGGGCTGGATGCCATGGCCGGTCAGACTGCGCCGGTGCTGGAAGTGGCTGCCCGACG
TGAAGGCAGCGTGGTCAGCATGGCCGTTCGCGATCATGGTGCCGGCTTGTCGGACGAGGCGCGCAACCACCTGTTCGAAC
CTTTCTACACCACCAAGCCAGCCGGCGAGGGCCTGGGCCTCGGGCTGGCGCTATCTCTGACCATTGCCGAAAGTTACGGC
GGCACGCTGAGCGCGCACAATGCGCCCGATGGCGGCGCTGTCTTCGTGCTGACCTTGCCAACGGCAGGAGACCCGAATGC
CTCATCTGACACTTGA

Upstream 100 bases:

>100_bases
AAATTGGCTGCGGTCGACTGAGAGAAATGGCCCAAATCGCTACGACGACGGCGTGAACCACATCGATCACGCCGTCCGGC
CCAGCCGCCGCAACTTGCTT

Downstream 100 bases:

>100_bases
ATACACCCGCAATCTAGCCGGCTTCGTCCCCGCGCACGCACTGGCAGCGGTCAATGAAGCGATGTTCGATTCCGGCCTGT
TCAGCGAACCGGATATAAAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MLGAAVAFCLLLGWLAYRTLFAVTLDNERRLAAQRLDAFALSLEATLSRHESLPGLLALDPSLAAVLGEPDSQPRIAAAN
AYLEAAQQGANVAVTFLIDAQGKTVAASNWRLPRSFVGHNYAFRPYFRDALANGLGRFYGVGVTTGEPGYFLAAPVREQG
RVLGVIVLKVGLESMEQALANAGDTLLLADADGVVFLSSDRQLRYRSLAPLGDAVQARLAETQQYGMQHITPLADQPLML
TATQPVRLALSGEAPRERLIHARPVGHSGWQVVQLGDPGEARATALGAAAAVAFAAAFTLGLAAHFRHRARRRDELRRVY
DELENRIAERTADLTEQIAALESTKAILRETRDAAVQAGKLATLGQMSAGISHELNQPLAALQTFADNASALLARGRYEE
VAENLQMISELVDRTGRIVRQLKTFARKEAPTPQAVTVASAIEHALMIVEPRRREIGAHIVVEPQSAALLVIAEAGRLEQ
VLVNLLRNGLDAMAGQTAPVLEVAARREGSVVSMAVRDHGAGLSDEARNHLFEPFYTTKPAGEGLGLGLALSLTIAESYG
GTLSAHNAPDGGAVFVLTLPTAGDPNASSDT

Sequences:

>Translated_591_residues
MLGAAVAFCLLLGWLAYRTLFAVTLDNERRLAAQRLDAFALSLEATLSRHESLPGLLALDPSLAAVLGEPDSQPRIAAAN
AYLEAAQQGANVAVTFLIDAQGKTVAASNWRLPRSFVGHNYAFRPYFRDALANGLGRFYGVGVTTGEPGYFLAAPVREQG
RVLGVIVLKVGLESMEQALANAGDTLLLADADGVVFLSSDRQLRYRSLAPLGDAVQARLAETQQYGMQHITPLADQPLML
TATQPVRLALSGEAPRERLIHARPVGHSGWQVVQLGDPGEARATALGAAAAVAFAAAFTLGLAAHFRHRARRRDELRRVY
DELENRIAERTADLTEQIAALESTKAILRETRDAAVQAGKLATLGQMSAGISHELNQPLAALQTFADNASALLARGRYEE
VAENLQMISELVDRTGRIVRQLKTFARKEAPTPQAVTVASAIEHALMIVEPRRREIGAHIVVEPQSAALLVIAEAGRLEQ
VLVNLLRNGLDAMAGQTAPVLEVAARREGSVVSMAVRDHGAGLSDEARNHLFEPFYTTKPAGEGLGLGLALSLTIAESYG
GTLSAHNAPDGGAVFVLTLPTAGDPNASSDT
>Mature_591_residues
MLGAAVAFCLLLGWLAYRTLFAVTLDNERRLAAQRLDAFALSLEATLSRHESLPGLLALDPSLAAVLGEPDSQPRIAAAN
AYLEAAQQGANVAVTFLIDAQGKTVAASNWRLPRSFVGHNYAFRPYFRDALANGLGRFYGVGVTTGEPGYFLAAPVREQG
RVLGVIVLKVGLESMEQALANAGDTLLLADADGVVFLSSDRQLRYRSLAPLGDAVQARLAETQQYGMQHITPLADQPLML
TATQPVRLALSGEAPRERLIHARPVGHSGWQVVQLGDPGEARATALGAAAAVAFAAAFTLGLAAHFRHRARRRDELRRVY
DELENRIAERTADLTEQIAALESTKAILRETRDAAVQAGKLATLGQMSAGISHELNQPLAALQTFADNASALLARGRYEE
VAENLQMISELVDRTGRIVRQLKTFARKEAPTPQAVTVASAIEHALMIVEPRRREIGAHIVVEPQSAALLVIAEAGRLEQ
VLVNLLRNGLDAMAGQTAPVLEVAARREGSVVSMAVRDHGAGLSDEARNHLFEPFYTTKPAGEGLGLGLALSLTIAESYG
GTLSAHNAPDGGAVFVLTLPTAGDPNASSDT

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=233, Percent_Identity=28.3261802575107, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=31.9838056680162, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786912, Length=223, Percent_Identity=29.5964125560538, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=227, Percent_Identity=29.5154185022026, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI145693157, Length=275, Percent_Identity=26.9090909090909, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790346, Length=219, Percent_Identity=28.310502283105, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62970; Mature: 62970

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGAAVAFCLLLGWLAYRTLFAVTLDNERRLAAQRLDAFALSLEATLSRHESLPGLLALD
CCHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
PSLAAVLGEPDSQPRIAAANAYLEAAQQGANVAVTFLIDAQGKTVAASNWRLPRSFVGHN
CHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCEEEEEEEECCCCEEEECCCCCCHHHHCCC
YAFRPYFRDALANGLGRFYGVGVTTGEPGYFLAAPVREQGRVLGVIVLKVGLESMEQALA
CEECHHHHHHHHHHHHHHEECCEECCCCCEEEECCCCCCCCEEEEHHHHHHHHHHHHHHH
NAGDTLLLADADGVVFLSSDRQLRYRSLAPLGDAVQARLAETQQYGMQHITPLADQPLML
CCCCEEEEECCCCEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHCHHHCCCCCCCCEEE
TATQPVRLALSGEAPRERLIHARPVGHSGWQVVQLGDPGEARATALGAAAAVAFAAAFTL
EECCCEEEEECCCCCHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
GLAAHFRHRARRRDELRRVYDELENRIAERTADLTEQIAALESTKAILRETRDAAVQAGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LATLGQMSAGISHELNQPLAALQTFADNASALLARGRYEEVAENLQMISELVDRTGRIVR
CHHHHHHHCCCHHHHCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
QLKTFARKEAPTPQAVTVASAIEHALMIVEPRRREIGAHIVVEPQSAALLVIAEAGRLEQ
HHHHHHHHCCCCCHHHHHHHHHHHHHEEECCHHHCCCCEEEECCCCCEEEEEECCCCHHH
VLVNLLRNGLDAMAGQTAPVLEVAARREGSVVSMAVRDHGAGLSDEARNHLFEPFYTTKP
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCCC
AGEGLGLGLALSLTIAESYGGTLSAHNAPDGGAVFVLTLPTAGDPNASSDT
CCCCCCEEEEEEEEEEHHCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MLGAAVAFCLLLGWLAYRTLFAVTLDNERRLAAQRLDAFALSLEATLSRHESLPGLLALD
CCHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
PSLAAVLGEPDSQPRIAAANAYLEAAQQGANVAVTFLIDAQGKTVAASNWRLPRSFVGHN
CHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCEEEEEEEECCCCEEEECCCCCCHHHHCCC
YAFRPYFRDALANGLGRFYGVGVTTGEPGYFLAAPVREQGRVLGVIVLKVGLESMEQALA
CEECHHHHHHHHHHHHHHEECCEECCCCCEEEECCCCCCCCEEEEHHHHHHHHHHHHHHH
NAGDTLLLADADGVVFLSSDRQLRYRSLAPLGDAVQARLAETQQYGMQHITPLADQPLML
CCCCEEEEECCCCEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHCHHHCCCCCCCCEEE
TATQPVRLALSGEAPRERLIHARPVGHSGWQVVQLGDPGEARATALGAAAAVAFAAAFTL
EECCCEEEEECCCCCHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
GLAAHFRHRARRRDELRRVYDELENRIAERTADLTEQIAALESTKAILRETRDAAVQAGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LATLGQMSAGISHELNQPLAALQTFADNASALLARGRYEEVAENLQMISELVDRTGRIVR
CHHHHHHHCCCHHHHCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
QLKTFARKEAPTPQAVTVASAIEHALMIVEPRRREIGAHIVVEPQSAALLVIAEAGRLEQ
HHHHHHHHCCCCCHHHHHHHHHHHHHEEECCHHHCCCCEEEECCCCCEEEEEECCCCHHH
VLVNLLRNGLDAMAGQTAPVLEVAARREGSVVSMAVRDHGAGLSDEARNHLFEPFYTTKP
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCCC
AGEGLGLGLALSLTIAESYGGTLSAHNAPDGGAVFVLTLPTAGDPNASSDT
CCCCCCEEEEEEEEEEHHCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]