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The map label for this gene is dctD [H]

Identifier: 71907771

GI number: 71907771

Start: 2317395

End: 2318723

Strand: Reverse

Name: dctD [H]

Synonym: Daro_2148

Alternate gene names: 71907771

Gene position: 2318723-2317395 (Counterclockwise)

Preceding gene: 71907772

Following gene: 71907767

Centisome position: 51.51

GC content: 63.58

Gene sequence:

>1329_bases
ATGGCTGATCACCCGGTCTTTCTGGTCGAGGACGATGCCGCCGTTCGCAAGGGCTGCGAGCAGGCCTTGTCGCTGGCTGA
CATTGCGGTGCGCGGCTTTGCCGATGGCGAATCCATGCTCGCTGCGCTGGCGACATCAAGCCCGGCCTTGGTGGTGACCG
ATGTCCGCCTGCCCGGCAAGGACGGCCTCAGCCTGTTGCGCGAACTGCGCCAGCTTGACCGCGAACTGCCGGTGCTGCTG
ATGACTGGTCACGGTGACGTGGCGATGGCCGTCGAAGCCATGCGCGAAGGGGCTTACGATTTCATCGAAAAGCCGTTTCC
TTCTGAGCGCCTGATCGCCGCCGTGCGCAGCGCCCTGGAAAAAAGGGCGCTGATTCTGGAGAACCGCCTGCTGAAGGAGC
GTATCGGCGACAACGGCGTGGCCCCTATCATCGGCCAGTCGCCGGCCATGCAGCATATCCGGCAACTGGTCGCCACGCTG
GCGCCGACCGGCGTCGATATCCTGATTAACGGCGAAACCGGCAGTGGCAAGGAGGTCGTGGCTCGTGCCATTCACGAAGC
CAGCGGCCGGCGTGGCCCTTTCGTCGCGATCAATTGCGGCGCCTTGCCGGAAACGGTGTTCGAGAGCGAATTGTTCGGCC
ACGAAGCCGGCGCCTTCACCGGGGCAGGGAAGCGACGTATCGGCCGCATCGAGCACGCCAACGGCGGCACACTGTTTCTC
GATGAAATCGAATCGATGCCGCTCAACCTACAGGTCAAGCTGCTGCGGGTGTTGCAGGAACGCTGTGTCGAACGACTCGG
CAGTAATGCTTCGATTCCGGTCGATTGCCGTCTCGTCGCGGCCAGCAAGGTCGATCTCAAGGCGGCCTCGGAGGCTGGCC
AGTTTCGGGCTGACGTTTATTATCGGCTCAATGTCGTCAGTCTCGAATTGCCGCCGCTGCGCCAGCGTCGCGAAGATATT
CCGCTCCTGATGGCGCATTTCCTGCACGAAGCGGCGCAGCGCTTCTCGCGGCCGGATGCGGTCTGGTCGGCGGCCGAACT
GGCCCGCTGGTCAGCTCATGCCTGGCCCGGCAATGTTCGCGAACTGAAGAATGTGGCCGAACGCTGGGCGCTCGGCTTGC
CTGATGCGCTGGGGGGCAACGCAATCCAGCCAGACACCACGCTGCCGCTGGCCGAGCAGGTCGATATCGCCGAGCGCGCC
ATTATCGAAACCGTCCTTGGCCAATCGGCCGGCAATGTGGCCCGGGCCGCTGAACTGCTGCAGACGCCGAAGAAGACGCT
TTACGACAAGCTGGTTCGCCACGGGATCAATGTCGAGAGCTTCCGGTAG

Upstream 100 bases:

>100_bases
GCGTTGAACACCACGGTCAATGGCGAAAAAGGCATGGACATCCAGCTCAGCGTGGAGACGGTCGATCTCGACCGCCCGAG
CTATGCCAAGGCGGTGATCC

Downstream 100 bases:

>100_bases
GGCATCGCCGGCCGTTTTTCAAAAATAAGAGCGGGTGGCTAATAGGTCATCTGCAGCCCTAATGTGAGGGGCTGCGCTCA
ACTCCGGCGCCATTGGTTTC

Product: helix-turn-helix, Fis-type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MADHPVFLVEDDAAVRKGCEQALSLADIAVRGFADGESMLAALATSSPALVVTDVRLPGKDGLSLLRELRQLDRELPVLL
MTGHGDVAMAVEAMREGAYDFIEKPFPSERLIAAVRSALEKRALILENRLLKERIGDNGVAPIIGQSPAMQHIRQLVATL
APTGVDILINGETGSGKEVVARAIHEASGRRGPFVAINCGALPETVFESELFGHEAGAFTGAGKRRIGRIEHANGGTLFL
DEIESMPLNLQVKLLRVLQERCVERLGSNASIPVDCRLVAASKVDLKAASEAGQFRADVYYRLNVVSLELPPLRQRREDI
PLLMAHFLHEAAQRFSRPDAVWSAAELARWSAHAWPGNVRELKNVAERWALGLPDALGGNAIQPDTTLPLAEQVDIAERA
IIETVLGQSAGNVARAAELLQTPKKTLYDKLVRHGINVESFR

Sequences:

>Translated_442_residues
MADHPVFLVEDDAAVRKGCEQALSLADIAVRGFADGESMLAALATSSPALVVTDVRLPGKDGLSLLRELRQLDRELPVLL
MTGHGDVAMAVEAMREGAYDFIEKPFPSERLIAAVRSALEKRALILENRLLKERIGDNGVAPIIGQSPAMQHIRQLVATL
APTGVDILINGETGSGKEVVARAIHEASGRRGPFVAINCGALPETVFESELFGHEAGAFTGAGKRRIGRIEHANGGTLFL
DEIESMPLNLQVKLLRVLQERCVERLGSNASIPVDCRLVAASKVDLKAASEAGQFRADVYYRLNVVSLELPPLRQRREDI
PLLMAHFLHEAAQRFSRPDAVWSAAELARWSAHAWPGNVRELKNVAERWALGLPDALGGNAIQPDTTLPLAEQVDIAERA
IIETVLGQSAGNVARAAELLQTPKKTLYDKLVRHGINVESFR
>Mature_441_residues
ADHPVFLVEDDAAVRKGCEQALSLADIAVRGFADGESMLAALATSSPALVVTDVRLPGKDGLSLLRELRQLDRELPVLLM
TGHGDVAMAVEAMREGAYDFIEKPFPSERLIAAVRSALEKRALILENRLLKERIGDNGVAPIIGQSPAMQHIRQLVATLA
PTGVDILINGETGSGKEVVARAIHEASGRRGPFVAINCGALPETVFESELFGHEAGAFTGAGKRRIGRIEHANGGTLFLD
EIESMPLNLQVKLLRVLQERCVERLGSNASIPVDCRLVAASKVDLKAASEAGQFRADVYYRLNVVSLELPPLRQRREDIP
LLMAHFLHEAAQRFSRPDAVWSAAELARWSAHAWPGNVRELKNVAERWALGLPDALGGNAIQPDTTLPLAEQVDIAERAI
IETVLGQSAGNVARAAELLQTPKKTLYDKLVRHGINVESFR

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=451, Percent_Identity=41.2416851441242, Blast_Score=323, Evalue=9e-90,
Organism=Escherichia coli, GI1790299, Length=469, Percent_Identity=39.8720682302772, Blast_Score=315, Evalue=4e-87,
Organism=Escherichia coli, GI1790437, Length=396, Percent_Identity=44.4444444444444, Blast_Score=309, Evalue=3e-85,
Organism=Escherichia coli, GI1788905, Length=445, Percent_Identity=40.4494382022472, Blast_Score=294, Evalue=8e-81,
Organism=Escherichia coli, GI87082117, Length=346, Percent_Identity=47.1098265895954, Blast_Score=251, Evalue=5e-68,
Organism=Escherichia coli, GI1789087, Length=355, Percent_Identity=45.0704225352113, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1789233, Length=307, Percent_Identity=41.042345276873, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI87082152, Length=317, Percent_Identity=40.0630914826498, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1786524, Length=248, Percent_Identity=45.9677419354839, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI87081872, Length=319, Percent_Identity=38.871473354232, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1787583, Length=254, Percent_Identity=39.7637795275591, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI87081858, Length=300, Percent_Identity=33.3333333333333, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1789828, Length=229, Percent_Identity=37.9912663755458, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1789809, Length=121, Percent_Identity=33.8842975206612, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789402, Length=101, Percent_Identity=36.6336633663366, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082012, Length=116, Percent_Identity=31.8965517241379, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 47978; Mature: 47847

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4 ; PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADHPVFLVEDDAAVRKGCEQALSLADIAVRGFADGESMLAALATSSPALVVTDVRLPGK
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCC
DGLSLLRELRQLDRELPVLLMTGHGDVAMAVEAMREGAYDFIEKPFPSERLIAAVRSALE
HHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHH
KRALILENRLLKERIGDNGVAPIIGQSPAMQHIRQLVATLAPTGVDILINGETGSGKEVV
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
ARAIHEASGRRGPFVAINCGALPETVFESELFGHEAGAFTGAGKRRIGRIEHANGGTLFL
HHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHCCCEEECCCCEEEE
DEIESMPLNLQVKLLRVLQERCVERLGSNASIPVDCRLVAASKVDLKAASEAGQFRADVY
EHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHCCCCEEEEE
YRLNVVSLELPPLRQRREDIPLLMAHFLHEAAQRFSRPDAVWSAAELARWSAHAWPGNVR
EEEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHH
ELKNVAERWALGLPDALGGNAIQPDTTLPLAEQVDIAERAIIETVLGQSAGNVARAAELL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
QTPKKTLYDKLVRHGINVESFR
HCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ADHPVFLVEDDAAVRKGCEQALSLADIAVRGFADGESMLAALATSSPALVVTDVRLPGK
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCC
DGLSLLRELRQLDRELPVLLMTGHGDVAMAVEAMREGAYDFIEKPFPSERLIAAVRSALE
HHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHH
KRALILENRLLKERIGDNGVAPIIGQSPAMQHIRQLVATLAPTGVDILINGETGSGKEVV
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
ARAIHEASGRRGPFVAINCGALPETVFESELFGHEAGAFTGAGKRRIGRIEHANGGTLFL
HHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHCCCEEECCCCEEEE
DEIESMPLNLQVKLLRVLQERCVERLGSNASIPVDCRLVAASKVDLKAASEAGQFRADVY
EHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHCCCCEEEEE
YRLNVVSLELPPLRQRREDIPLLMAHFLHEAAQRFSRPDAVWSAAELARWSAHAWPGNVR
EEEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHH
ELKNVAERWALGLPDALGGNAIQPDTTLPLAEQVDIAERAIIETVLGQSAGNVARAAELL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
QTPKKTLYDKLVRHGINVESFR
HCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]