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The map label for this gene is degP [H]

Identifier: 71907529

GI number: 71907529

Start: 2042669

End: 2044138

Strand: Reverse

Name: degP [H]

Synonym: Daro_1900

Alternate gene names: 71907529

Gene position: 2044138-2042669 (Counterclockwise)

Preceding gene: 71907530

Following gene: 71907528

Centisome position: 45.41

GC content: 62.99

Gene sequence:

>1470_bases
ATGAAACTGAAACCCCTGAAAATGACAGTTGCCGCCATTGCTGTCGCTGCTGCGCTGGGCGGCGCCTATTCGCTGGGTCA
ATACGCGCCCTTTGCCAGTGCCAACGCGACAACCCAGCCTGCCGCTAGCAGCGTCGCCCCTGCCGCCGCTCCGGTCAGCA
CGCCTAACGGCCTGCCGGACATGCGCAGCATTGTCGCCAACAATGCCCAGGCCGTGGTCAACATCAGCGTGACCGGAACG
CGCAAGACGGGCGCCAACCTTCCCGGCATGCCGCAACTCGACCCCGATGACCCGCTTTACCAGTTCTTCCGCCGCTTCGG
TGGACAGATGCCGCAGGACAATGAACCCACGCACGGCCTTGGCTCCGGTTTCATCGTGACGCCTGACGGCACGGTGTTGA
CCAATGCCCATGTCGTCGACGGCGCCGAGGAAGTGACCGTCAAGCTTAACGACAAGCGCGAATTCAAGGCCAAGGTGCTT
GGCCTGGACAAGGCAAGCGATGTGGCCGTCCTGAGAATCGACGCCAAAAACCTGCCTACGGTGAAGATCGGTTCATCGAC
GCAGACTGCCGTCGGCGAATGGGTGCTGGCCATCGGCTCGCCGTTCGGATTCGAAAGCAGCGCCAGTGCCGGCATTGTCT
CGGCCAAGTCGCGCAACCTGCCGGATGGCAGCTACGTGCCCTTCATCCAGACCGATGTGGCAGTGAATCCCGGCAACTCC
GGCGGTCCGCTGTTCAACATGAACGGCGAGGTAATCGGCATCAATTCGCAGATCTACTCACGCAGCGGCGGTTACCAGGG
GCTGTCTTTTGCCATTCCGATCGAGGTCGCGATGAATGTCGAAAAGCAGATCGTCACGCACGGCAAGGTGCAACGCGGCA
AGCTCGGCGTCACCATCCAGGAGGTCAACCAGTCGCTGGCAGACAGCTTCGGCCTGCCCAAACCGGCCGGCGCGCTGGTC
GCTGCAGTCGAGAAAGGCAGCCCGGCGGCCAAGGCGGGTCTGGAGCCTGGCGATGTCATTCTCGGCATCGACGGCAAAAC
CGTCGAGACGCCCGGCGAACTCCCTGCCGCCATCGCCACCAAGCTGCCCGGCGAATCGGCCCGCCTGCAAATCTGGCGCA
AGGGTGGAACGCAGAACATTGATGTCAAGGTTGGCAGTTTCGGAGACGAGAAAGTGGCCGCGAACGACACACAGCCCGCC
ACCAAAGGTCGCCTCGGCGTCGCCGTGCGCCCACTGACGCCGGAAGAACGACGCCAGGCCGAGATCAAGGGTGGCGTGCT
CGTCGAGCAAGCCGACGGCGCCGCCGGTCGTGCCGGCATCCGGCCGGGCGACATCATTGTGTCGGTCAACGGACAGCCGA
TTGGCGACGTCGAACAACTGCGCAGCCTGATCGCCAAATCCGGTAAGAAGGCAGCCATCCTGATCGAACGCGGCGATTCT
CGACTATTCGTTCCGGTCGACCTCGGTTAA

Upstream 100 bases:

>100_bases
CTACAAGGGTAATGAGCGAGTCGCTCACCCCGCTGGACTATCCCTGCATGGCAAGCATCGCTGATCAATGTTCAACAAAC
CCACCCGACAAGAGGTCAAC

Downstream 100 bases:

>100_bases
ACACGGAAAAGGCAGATCGGACGCCCCCCCAAGACTGAAATATTGATGCGCCGGCGTAAGTTGGCCAGGAATGCCTTCCA
TACCCTTTGTGGAAGGCATT

Product: peptidase S1C, Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MKLKPLKMTVAAIAVAAALGGAYSLGQYAPFASANATTQPAASSVAPAAAPVSTPNGLPDMRSIVANNAQAVVNISVTGT
RKTGANLPGMPQLDPDDPLYQFFRRFGGQMPQDNEPTHGLGSGFIVTPDGTVLTNAHVVDGAEEVTVKLNDKREFKAKVL
GLDKASDVAVLRIDAKNLPTVKIGSSTQTAVGEWVLAIGSPFGFESSASAGIVSAKSRNLPDGSYVPFIQTDVAVNPGNS
GGPLFNMNGEVIGINSQIYSRSGGYQGLSFAIPIEVAMNVEKQIVTHGKVQRGKLGVTIQEVNQSLADSFGLPKPAGALV
AAVEKGSPAAKAGLEPGDVILGIDGKTVETPGELPAAIATKLPGESARLQIWRKGGTQNIDVKVGSFGDEKVAANDTQPA
TKGRLGVAVRPLTPEERRQAEIKGGVLVEQADGAAGRAGIRPGDIIVSVNGQPIGDVEQLRSLIAKSGKKAAILIERGDS
RLFVPVDLG

Sequences:

>Translated_489_residues
MKLKPLKMTVAAIAVAAALGGAYSLGQYAPFASANATTQPAASSVAPAAAPVSTPNGLPDMRSIVANNAQAVVNISVTGT
RKTGANLPGMPQLDPDDPLYQFFRRFGGQMPQDNEPTHGLGSGFIVTPDGTVLTNAHVVDGAEEVTVKLNDKREFKAKVL
GLDKASDVAVLRIDAKNLPTVKIGSSTQTAVGEWVLAIGSPFGFESSASAGIVSAKSRNLPDGSYVPFIQTDVAVNPGNS
GGPLFNMNGEVIGINSQIYSRSGGYQGLSFAIPIEVAMNVEKQIVTHGKVQRGKLGVTIQEVNQSLADSFGLPKPAGALV
AAVEKGSPAAKAGLEPGDVILGIDGKTVETPGELPAAIATKLPGESARLQIWRKGGTQNIDVKVGSFGDEKVAANDTQPA
TKGRLGVAVRPLTPEERRQAEIKGGVLVEQADGAAGRAGIRPGDIIVSVNGQPIGDVEQLRSLIAKSGKKAAILIERGDS
RLFVPVDLG
>Mature_489_residues
MKLKPLKMTVAAIAVAAALGGAYSLGQYAPFASANATTQPAASSVAPAAAPVSTPNGLPDMRSIVANNAQAVVNISVTGT
RKTGANLPGMPQLDPDDPLYQFFRRFGGQMPQDNEPTHGLGSGFIVTPDGTVLTNAHVVDGAEEVTVKLNDKREFKAKVL
GLDKASDVAVLRIDAKNLPTVKIGSSTQTAVGEWVLAIGSPFGFESSASAGIVSAKSRNLPDGSYVPFIQTDVAVNPGNS
GGPLFNMNGEVIGINSQIYSRSGGYQGLSFAIPIEVAMNVEKQIVTHGKVQRGKLGVTIQEVNQSLADSFGLPKPAGALV
AAVEKGSPAAKAGLEPGDVILGIDGKTVETPGELPAAIATKLPGESARLQIWRKGGTQNIDVKVGSFGDEKVAANDTQPA
TKGRLGVAVRPLTPEERRQAEIKGGVLVEQADGAAGRAGIRPGDIIVSVNGQPIGDVEQLRSLIAKSGKKAAILIERGDS
RLFVPVDLG

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI7019477, Length=273, Percent_Identity=38.0952380952381, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI4506141, Length=289, Percent_Identity=33.9100346020761, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI24308541, Length=255, Percent_Identity=35.2941176470588, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI22129776, Length=287, Percent_Identity=34.1463414634146, Blast_Score=142, Evalue=9e-34,
Organism=Escherichia coli, GI1789629, Length=457, Percent_Identity=33.9168490153173, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1786356, Length=469, Percent_Identity=33.2622601279318, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1789630, Length=273, Percent_Identity=33.6996336996337, Blast_Score=150, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24646839, Length=319, Percent_Identity=33.5423197492163, Blast_Score=147, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 50424; Mature: 50424

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKPLKMTVAAIAVAAALGGAYSLGQYAPFASANATTQPAASSVAPAAAPVSTPNGLPD
CCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
MRSIVANNAQAVVNISVTGTRKTGANLPGMPQLDPDDPLYQFFRRFGGQMPQDNEPTHGL
HHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
GSGFIVTPDGTVLTNAHVVDGAEEVTVKLNDKREFKAKVLGLDKASDVAVLRIDAKNLPT
CCCEEECCCCCEEEEEEEECCCEEEEEEECCCCCEEEEEEECCCCCCEEEEEECCCCCCE
VKIGSSTQTAVGEWVLAIGSPFGFESSASAGIVSAKSRNLPDGSYVPFIQTDVAVNPGNS
EEECCCCCHHHHHEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEECEEECCCCC
GGPLFNMNGEVIGINSQIYSRSGGYQGLSFAIPIEVAMNVEKQIVTHGKVQRGKLGVTIQ
CCCEEECCCCEEEECHHEEECCCCCCCEEEEEEEEEEECCHHHHHHCCCEECCCCCEEHH
EVNQSLADSFGLPKPAGALVAAVEKGSPAAKAGLEPGDVILGIDGKTVETPGELPAAIAT
HHHHHHHHHCCCCCCCCCEEEEECCCCCHHHCCCCCCCEEEECCCCEECCCCCCCHHHHH
KLPGESARLQIWRKGGTQNIDVKVGSFGDEKVAANDTQPATKGRLGVAVRPLTPEERRQA
CCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHH
EIKGGVLVEQADGAAGRAGIRPGDIIVSVNGQPIGDVEQLRSLIAKSGKKAAILIERGDS
HCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEECCC
RLFVPVDLG
EEEEEEECC
>Mature Secondary Structure
MKLKPLKMTVAAIAVAAALGGAYSLGQYAPFASANATTQPAASSVAPAAAPVSTPNGLPD
CCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
MRSIVANNAQAVVNISVTGTRKTGANLPGMPQLDPDDPLYQFFRRFGGQMPQDNEPTHGL
HHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
GSGFIVTPDGTVLTNAHVVDGAEEVTVKLNDKREFKAKVLGLDKASDVAVLRIDAKNLPT
CCCEEECCCCCEEEEEEEECCCEEEEEEECCCCCEEEEEEECCCCCCEEEEEECCCCCCE
VKIGSSTQTAVGEWVLAIGSPFGFESSASAGIVSAKSRNLPDGSYVPFIQTDVAVNPGNS
EEECCCCCHHHHHEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEECEEECCCCC
GGPLFNMNGEVIGINSQIYSRSGGYQGLSFAIPIEVAMNVEKQIVTHGKVQRGKLGVTIQ
CCCEEECCCCEEEECHHEEECCCCCCCEEEEEEEEEEECCHHHHHHCCCEECCCCCEEHH
EVNQSLADSFGLPKPAGALVAAVEKGSPAAKAGLEPGDVILGIDGKTVETPGELPAAIAT
HHHHHHHHHCCCCCCCCCEEEEECCCCCHHHCCCCCCCEEEECCCCEECCCCCCCHHHHH
KLPGESARLQIWRKGGTQNIDVKVGSFGDEKVAANDTQPATKGRLGVAVRPLTPEERRQA
CCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHH
EIKGGVLVEQADGAAGRAGIRPGDIIVSVNGQPIGDVEQLRSLIAKSGKKAAILIERGDS
HCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEECCC
RLFVPVDLG
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]