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The map label for this gene is luxQ [H]

Identifier: 71907253

GI number: 71907253

Start: 1739474

End: 1741882

Strand: Reverse

Name: luxQ [H]

Synonym: Daro_1622

Alternate gene names: 71907253

Gene position: 1741882-1739474 (Counterclockwise)

Preceding gene: 71907256

Following gene: 71907252

Centisome position: 38.7

GC content: 51.85

Gene sequence:

>2409_bases
ATGCAGGGAAATGAGGAAATCGTTAAGAGGTTGTTCCCTAGGTATCTGGCCCTGGCCCTCACATTGCTCCTCGTCATGGG
CAATACGCTGCCGCCGACCAAATTCTTCTCTTCCCCGGAACACTACCTCCCGCTACATACCGTTCTCGAATTCCTTGCCA
TGACCATTTCGGCAATGGTTTTCAGCCTCTCGTGGAACCTGAGAACGCAACCACGGAGCAGCAATAACCTGCTGTTGGGA
ATTGGCCTGATGATTGTCTGCATGATCGACATGGCTCACACCCTGTCGTATGCCGGCATGCCAAAGTTGGTAACACCCAG
CTCACCGGAAAAGGCCATCAATTTCTGGCTAGCAGGACGCTTTGTTGCCGCGATATCGCTTCTCGCCTACGCGACCTTGC
CCGAAAAAACATGGAATGCTCTGGTTTCTGCACTGGCCTTATTCGGCGGGCTTTTATTTGCAGCGCTGGTTTGGTGGATC
GGTCTTTTTCATGCAGACACGCTGCCCTGCACATTTATTCCAGGAGAAGGCCTGACTGTATTCAAAATTGCCGCCGAATA
TAGTTTGAGCGCTTTTTACGCCATCGCAGCCCTGCTCCTGTATTTGCGCGGCCAGAAAACACGTCGCCCCGAGCTTTATT
GGGTTGCCGCCGCATCCTGGACTCTCGGCCTTGCTGAGATGTTCTTTACGCTCTATGTGGACGTCACAGACCTCTTCAAT
CTGCTTGGACACATCTACAAGGCCTTTGCTTACTGGATGATTTATCGGGCACTCTTCGCGGAAGGTGTGCGTGCACCCCA
ACATGCACTAAGCCGACAGGCGCAACGACTATCTGCCATTCTCGACGGCACAAACGTCGGTACGTGGGAATGGAATATAC
AGAACGGCAAAGTCATTATTAACGAGCGCTGGGCCAACATTATCGGCTACGACCTCGCTGAAATGCAGCCAGTGAATTTT
CAGACATGGGTCGGGTTTGTCCACCCAGAGGATATTCAGACATCCCAATTTTTGCTTGAACAGCATTTTTCCGGAGAAAT
ACCCTATTACGAATGTGTTGTCCGCATGCGGCACAAGGATGGTCACTGGGTTTGGGTACTCGACCGCGGCCGCATCGCAA
CCTGGGCAGCCGACGGCAAACCGCTCTGGATGTTTGGCACCCACCAGGACATCACGGCACAAAAAATGGCTGAGCAGGAA
TTGCTCGCTCATCGTGACCATCTGGAAGAACTGGTCAGTATCAGAACGCATGATCTTTCTATCGCCAAAGATGCCGCCGA
TGCCGCAAGTCGGGCAAAAAGCGCCTTCTTGTCCAACATGAGTCACGAGTTGCGGACCCCGCTACACGGCATTCTTGGTT
TGGGTAATATCTTGAAGGGCAAGATCAATGACCAGCATAGCCGGTTACTGGTCGCCAAATTACTGACCACAGCGTCACAC
ATGAATGATGTCGTCAATAACGTCCTCGACCTGGCACGAATTGAGGCGGGCCGCTTTGTAATCAAAAACGCTGATTTCTC
GACCGCTACGCTAAAAGAAAAACTGGATTCGATCTGCGCCATCAACGCCCAAGCCAAAGGACTTGAATACAAAGCGAATT
TTGATTTACCTCCCCGAGTTCACGGCGACTCAGTACAGATCCTTCAGGTGCTGATCAACATTGTCGGCAACGCAATCAAA
TTTACAGAACATGGCAGCATCCACGTCTCCGCTTTTGTTCTCTCTGAAGAAAGCTCCCGCTTGCGGCTGTGTTTTGAAGT
CCGCGATACCGGCATAGGTATTCCTCCAGAAAAACTGGAAAGCATATTTGAAGACTTCGAACAAGCTGATGGCGGCATCA
ATCGGAAATATGGAGGCTCGGGCCTGGGCCTTGCCATCACACGCCGACTTGTGCAAATGATGGAAGGAGAAACACAGGTT
GAGAGCCAGCCAGGCATTGGCAGCCTCTTCCGCTTTGAAATCAATGTCGGAAAAGTCGCCAGCCATGATACCGGCGGTGC
TACGGAAGCCTCACCGGCTCCCCCAGTAAACCTCCTGGGGGCACACATACTGGTGGTTGATGACGAGCCACTAAACGGCA
TGATATTGACCGACATTCTCGCCGAGCATCAGGTCAACGTATCGCTTGCAGAAAATGGCCAAAGTGCCATCGATCTGGCC
AAGACGGAACATTTCGACCTGATCCTGATGGATATGCAAATGCCTGTCCTCAACGGACTGGCTGCGACTGAACAAATTCG
CCAGCTGCCAGGGTATGAAACAACCCCCATCATTGCCCTGACGGCAAATGTTCAGCCAGAGCACAAGGCACAGGCCGAAG
GAGCCGGGATGAACGATTTCCTGGGAAAACCATTCAATGGCGAGGTACTTCTGGCAAAAATCAGCTACTGGCTACAAGCA
AGTAAATAG

Upstream 100 bases:

>100_bases
CCGGATTCTCATACTCTGGAAGACCATTGCCATACTGAAAGTGCTAAGGTACGCCCCCAAGAAAATTGCTCACTAACAAC
AAGGGGGGAAGACAGAGCAC

Downstream 100 bases:

>100_bases
TCAGAAAATAGCGCACATCGCCCCATCTACTGCGCTCTTCAGTCGCGTGAAAGCCCCCAGGCAGTCTTGGCTTTCTGCAA
CGAGCCGGGCTGTTTCGGAC

Product: PAS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 802; Mature: 802

Protein sequence:

>802_residues
MQGNEEIVKRLFPRYLALALTLLLVMGNTLPPTKFFSSPEHYLPLHTVLEFLAMTISAMVFSLSWNLRTQPRSSNNLLLG
IGLMIVCMIDMAHTLSYAGMPKLVTPSSPEKAINFWLAGRFVAAISLLAYATLPEKTWNALVSALALFGGLLFAALVWWI
GLFHADTLPCTFIPGEGLTVFKIAAEYSLSAFYAIAALLLYLRGQKTRRPELYWVAAASWTLGLAEMFFTLYVDVTDLFN
LLGHIYKAFAYWMIYRALFAEGVRAPQHALSRQAQRLSAILDGTNVGTWEWNIQNGKVIINERWANIIGYDLAEMQPVNF
QTWVGFVHPEDIQTSQFLLEQHFSGEIPYYECVVRMRHKDGHWVWVLDRGRIATWAADGKPLWMFGTHQDITAQKMAEQE
LLAHRDHLEELVSIRTHDLSIAKDAADAASRAKSAFLSNMSHELRTPLHGILGLGNILKGKINDQHSRLLVAKLLTTASH
MNDVVNNVLDLARIEAGRFVIKNADFSTATLKEKLDSICAINAQAKGLEYKANFDLPPRVHGDSVQILQVLINIVGNAIK
FTEHGSIHVSAFVLSEESSRLRLCFEVRDTGIGIPPEKLESIFEDFEQADGGINRKYGGSGLGLAITRRLVQMMEGETQV
ESQPGIGSLFRFEINVGKVASHDTGGATEASPAPPVNLLGAHILVVDDEPLNGMILTDILAEHQVNVSLAENGQSAIDLA
KTEHFDLILMDMQMPVLNGLAATEQIRQLPGYETTPIIALTANVQPEHKAQAEGAGMNDFLGKPFNGEVLLAKISYWLQA
SK

Sequences:

>Translated_802_residues
MQGNEEIVKRLFPRYLALALTLLLVMGNTLPPTKFFSSPEHYLPLHTVLEFLAMTISAMVFSLSWNLRTQPRSSNNLLLG
IGLMIVCMIDMAHTLSYAGMPKLVTPSSPEKAINFWLAGRFVAAISLLAYATLPEKTWNALVSALALFGGLLFAALVWWI
GLFHADTLPCTFIPGEGLTVFKIAAEYSLSAFYAIAALLLYLRGQKTRRPELYWVAAASWTLGLAEMFFTLYVDVTDLFN
LLGHIYKAFAYWMIYRALFAEGVRAPQHALSRQAQRLSAILDGTNVGTWEWNIQNGKVIINERWANIIGYDLAEMQPVNF
QTWVGFVHPEDIQTSQFLLEQHFSGEIPYYECVVRMRHKDGHWVWVLDRGRIATWAADGKPLWMFGTHQDITAQKMAEQE
LLAHRDHLEELVSIRTHDLSIAKDAADAASRAKSAFLSNMSHELRTPLHGILGLGNILKGKINDQHSRLLVAKLLTTASH
MNDVVNNVLDLARIEAGRFVIKNADFSTATLKEKLDSICAINAQAKGLEYKANFDLPPRVHGDSVQILQVLINIVGNAIK
FTEHGSIHVSAFVLSEESSRLRLCFEVRDTGIGIPPEKLESIFEDFEQADGGINRKYGGSGLGLAITRRLVQMMEGETQV
ESQPGIGSLFRFEINVGKVASHDTGGATEASPAPPVNLLGAHILVVDDEPLNGMILTDILAEHQVNVSLAENGQSAIDLA
KTEHFDLILMDMQMPVLNGLAATEQIRQLPGYETTPIIALTANVQPEHKAQAEGAGMNDFLGKPFNGEVLLAKISYWLQA
SK
>Mature_802_residues
MQGNEEIVKRLFPRYLALALTLLLVMGNTLPPTKFFSSPEHYLPLHTVLEFLAMTISAMVFSLSWNLRTQPRSSNNLLLG
IGLMIVCMIDMAHTLSYAGMPKLVTPSSPEKAINFWLAGRFVAAISLLAYATLPEKTWNALVSALALFGGLLFAALVWWI
GLFHADTLPCTFIPGEGLTVFKIAAEYSLSAFYAIAALLLYLRGQKTRRPELYWVAAASWTLGLAEMFFTLYVDVTDLFN
LLGHIYKAFAYWMIYRALFAEGVRAPQHALSRQAQRLSAILDGTNVGTWEWNIQNGKVIINERWANIIGYDLAEMQPVNF
QTWVGFVHPEDIQTSQFLLEQHFSGEIPYYECVVRMRHKDGHWVWVLDRGRIATWAADGKPLWMFGTHQDITAQKMAEQE
LLAHRDHLEELVSIRTHDLSIAKDAADAASRAKSAFLSNMSHELRTPLHGILGLGNILKGKINDQHSRLLVAKLLTTASH
MNDVVNNVLDLARIEAGRFVIKNADFSTATLKEKLDSICAINAQAKGLEYKANFDLPPRVHGDSVQILQVLINIVGNAIK
FTEHGSIHVSAFVLSEESSRLRLCFEVRDTGIGIPPEKLESIFEDFEQADGGINRKYGGSGLGLAITRRLVQMMEGETQV
ESQPGIGSLFRFEINVGKVASHDTGGATEASPAPPVNLLGAHILVVDDEPLNGMILTDILAEHQVNVSLAENGQSAIDLA
KTEHFDLILMDMQMPVLNGLAATEQIRQLPGYETTPIIALTANVQPEHKAQAEGAGMNDFLGKPFNGEVLLAKISYWLQA
SK

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=381, Percent_Identity=33.3333333333333, Blast_Score=200, Evalue=3e-52,
Organism=Escherichia coli, GI1789149, Length=255, Percent_Identity=38.4313725490196, Blast_Score=182, Evalue=7e-47,
Organism=Escherichia coli, GI87081816, Length=415, Percent_Identity=31.0843373493976, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1788713, Length=388, Percent_Identity=30.1546391752577, Blast_Score=163, Evalue=4e-41,
Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=36.5957446808511, Blast_Score=149, Evalue=1e-36,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=31.7073170731707, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786600, Length=265, Percent_Identity=30.5660377358491, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790346, Length=214, Percent_Identity=29.9065420560748, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788393, Length=208, Percent_Identity=28.3653846153846, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=29.6296296296296, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=23.6734693877551, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=27.1551724137931, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790300, Length=265, Percent_Identity=25.6603773584906, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1786784, Length=118, Percent_Identity=35.5932203389831, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1790861, Length=211, Percent_Identity=28.9099526066351, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786783, Length=211, Percent_Identity=25.1184834123223, Blast_Score=63, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=152, Percent_Identity=36.1842105263158, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323034, Length=142, Percent_Identity=33.0985915492958, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322000, Length=120, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88851; Mature: 88851

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGNEEIVKRLFPRYLALALTLLLVMGNTLPPTKFFSSPEHYLPLHTVLEFLAMTISAMV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHH
FSLSWNLRTQPRSSNNLLLGIGLMIVCMIDMAHTLSYAGMPKLVTPSSPEKAINFWLAGR
HHHCCCCEECCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
FVAAISLLAYATLPEKTWNALVSALALFGGLLFAALVWWIGLFHADTLPCTFIPGEGLTV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEE
FKIAAEYSLSAFYAIAALLLYLRGQKTRRPELYWVAAASWTLGLAEMFFTLYVDVTDLFN
EEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHH
LLGHIYKAFAYWMIYRALFAEGVRAPQHALSRQAQRLSAILDGTNVGTWEWNIQNGKVII
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEE
NERWANIIGYDLAEMQPVNFQTWVGFVHPEDIQTSQFLLEQHFSGEIPYYECVVRMRHKD
EECHHHHHCCCHHHCCCCCHHHEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCC
GHWVWVLDRGRIATWAADGKPLWMFGTHQDITAQKMAEQELLAHRDHLEELVSIRTHDLS
CCEEEEEECCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
IAKDAADAASRAKSAFLSNMSHELRTPLHGILGLGNILKGKINDQHSRLLVAKLLTTASH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHH
MNDVVNNVLDLARIEAGRFVIKNADFSTATLKEKLDSICAINAQAKGLEYKANFDLPPRV
HHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHEEECCCCCCCEEEECCCCCCCC
HGDSVQILQVLINIVGNAIKFTEHGSIHVSAFVLSEESSRLRLCFEVRDTGIGIPPEKLE
CCCHHHHHHHHHHHHCCCEEEECCCCEEEEEEEEECCCCCEEEEEEEECCCCCCCHHHHH
SIFEDFEQADGGINRKYGGSGLGLAITRRLVQMMEGETQVESQPGIGSLFRFEINVGKVA
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCEE
SHDTGGATEASPAPPVNLLGAHILVVDDEPLNGMILTDILAEHQVNVSLAENGQSAIDLA
CCCCCCCCCCCCCCCHHCCCCEEEEECCCCCCCCHHHHHHHHHCCEEEECCCCCHHHHHH
KTEHFDLILMDMQMPVLNGLAATEQIRQLPGYETTPIIALTANVQPEHKAQAEGAGMNDF
CCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHCCCCCCHHH
LGKPFNGEVLLAKISYWLQASK
CCCCCCCCEEEEEEHHHHHCCC
>Mature Secondary Structure
MQGNEEIVKRLFPRYLALALTLLLVMGNTLPPTKFFSSPEHYLPLHTVLEFLAMTISAMV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHH
FSLSWNLRTQPRSSNNLLLGIGLMIVCMIDMAHTLSYAGMPKLVTPSSPEKAINFWLAGR
HHHCCCCEECCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
FVAAISLLAYATLPEKTWNALVSALALFGGLLFAALVWWIGLFHADTLPCTFIPGEGLTV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEE
FKIAAEYSLSAFYAIAALLLYLRGQKTRRPELYWVAAASWTLGLAEMFFTLYVDVTDLFN
EEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHH
LLGHIYKAFAYWMIYRALFAEGVRAPQHALSRQAQRLSAILDGTNVGTWEWNIQNGKVII
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEE
NERWANIIGYDLAEMQPVNFQTWVGFVHPEDIQTSQFLLEQHFSGEIPYYECVVRMRHKD
EECHHHHHCCCHHHCCCCCHHHEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCC
GHWVWVLDRGRIATWAADGKPLWMFGTHQDITAQKMAEQELLAHRDHLEELVSIRTHDLS
CCEEEEEECCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
IAKDAADAASRAKSAFLSNMSHELRTPLHGILGLGNILKGKINDQHSRLLVAKLLTTASH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHH
MNDVVNNVLDLARIEAGRFVIKNADFSTATLKEKLDSICAINAQAKGLEYKANFDLPPRV
HHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHEEECCCCCCCEEEECCCCCCCC
HGDSVQILQVLINIVGNAIKFTEHGSIHVSAFVLSEESSRLRLCFEVRDTGIGIPPEKLE
CCCHHHHHHHHHHHHCCCEEEECCCCEEEEEEEEECCCCCEEEEEEEECCCCCCCHHHHH
SIFEDFEQADGGINRKYGGSGLGLAITRRLVQMMEGETQVESQPGIGSLFRFEINVGKVA
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCEE
SHDTGGATEASPAPPVNLLGAHILVVDDEPLNGMILTDILAEHQVNVSLAENGQSAIDLA
CCCCCCCCCCCCCCCHHCCCCEEEEECCCCCCCCHHHHHHHHHCCEEEECCCCCHHHHHH
KTEHFDLILMDMQMPVLNGLAATEQIRQLPGYETTPIIALTANVQPEHKAQAEGAGMNDF
CCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHCCCCCCHHH
LGKPFNGEVLLAKISYWLQASK
CCCCCCCCEEEEEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA