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The map label for this gene is dnaQ [H]

Identifier: 71907224

GI number: 71907224

Start: 1708387

End: 1709103

Strand: Reverse

Name: dnaQ [H]

Synonym: Daro_1592

Alternate gene names: 71907224

Gene position: 1709103-1708387 (Counterclockwise)

Preceding gene: 71907225

Following gene: 71907223

Centisome position: 37.97

GC content: 60.25

Gene sequence:

>717_bases
ATGCGACAGATCGTTCTCGACACTGAAACCACCGGCCTAGACCCCCGCTCAGGCCACCGTATCATCGAAGTGGCGTGCAT
CGAGATGGTGAACCGCCGCTTTACCGGTCACCACCTGCACAAATATATTAACCCTGAGCGCGAAATCGACGAAGGCGCCC
AGGCGGTGCACGGCATCACCCTTGAATTCCTGGCCGACAAGCCTAAATTCGCCGACATCGCCGACGAGTTTCTTGAGTTC
ATCAACGGCGCCGAATTGATCATCCACAACGCGCCTTTCGACATCGGCTTCCTCAATGCCGAACTCGACCGGCTCGGCCG
GGTGCCGGTCGGCACCATTTGCAATGGCGTCATCGACACCCTGCGCATGGCCAAGGAGTTGCATCCCGGCAAGCGCAACA
GCCTTGATGCGCTGTGTGAACGCTACGAGATCGACAATTCGAGCCGGACCCTGCACGGCGCGCTGCTCGATACGGAATTG
CTGGCCGACGTTTTCCTGGCCATGACCCGAGGCCAGAACAGCCTGATGATCGAACCCGATGCAGAGCCACGTCCGAACAT
CGGCGCCGACGGCCAGGTTCGCGAACGCAAGCCACTCAGCGTACGCCGCGCCGCGCCGGAGGAAATCGCCGAGCACGAAA
CGGTATTGGCGGCAATCGACAAGGAATCGAAGGGTGCCTGCATCTGGTTGCCCAAGCCAGAAACCGAAGCAGCCTGA

Upstream 100 bases:

>100_bases
ATGGATCTGGGTCAGGGGGCATTCCGGGCATCCGGAAAACGAACGCGCCGATGCATTGGCCAACCGTGGCATCGAAGAAT
TGAAGGGTTAAGGAAGCACC

Downstream 100 bases:

>100_bases
TTTCGACATGCTGCCAATTTCCCTGCTCATCTGGATCTCTCTGGAAGTCACCGGCTACCTCTACATCGGTCGCCACTTCA
TGCATCTCGACTGGCCGCTC

Product: DNA polymerase III, epsilon subunit:DNA polymerase 3, epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MRQIVLDTETTGLDPRSGHRIIEVACIEMVNRRFTGHHLHKYINPEREIDEGAQAVHGITLEFLADKPKFADIADEFLEF
INGAELIIHNAPFDIGFLNAELDRLGRVPVGTICNGVIDTLRMAKELHPGKRNSLDALCERYEIDNSSRTLHGALLDTEL
LADVFLAMTRGQNSLMIEPDAEPRPNIGADGQVRERKPLSVRRAAPEEIAEHETVLAAIDKESKGACIWLPKPETEAA

Sequences:

>Translated_238_residues
MRQIVLDTETTGLDPRSGHRIIEVACIEMVNRRFTGHHLHKYINPEREIDEGAQAVHGITLEFLADKPKFADIADEFLEF
INGAELIIHNAPFDIGFLNAELDRLGRVPVGTICNGVIDTLRMAKELHPGKRNSLDALCERYEIDNSSRTLHGALLDTEL
LADVFLAMTRGQNSLMIEPDAEPRPNIGADGQVRERKPLSVRRAAPEEIAEHETVLAAIDKESKGACIWLPKPETEAA
>Mature_238_residues
MRQIVLDTETTGLDPRSGHRIIEVACIEMVNRRFTGHHLHKYINPEREIDEGAQAVHGITLEFLADKPKFADIADEFLEF
INGAELIIHNAPFDIGFLNAELDRLGRVPVGTICNGVIDTLRMAKELHPGKRNSLDALCERYEIDNSSRTLHGALLDTEL
LADVFLAMTRGQNSLMIEPDAEPRPNIGADGQVRERKPLSVRRAAPEEIAEHETVLAAIDKESKGACIWLPKPETEAA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=237, Percent_Identity=53.1645569620253, Blast_Score=238, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26472; Mature: 26472

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQIVLDTETTGLDPRSGHRIIEVACIEMVNRRFTGHHLHKYINPEREIDEGAQAVHGIT
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHCCC
LEFLADKPKFADIADEFLEFINGAELIIHNAPFDIGFLNAELDRLGRVPVGTICNGVIDT
EEECCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEHHHHHHHCCCCHHHHHHHHHHH
LRMAKELHPGKRNSLDALCERYEIDNSSRTLHGALLDTELLADVFLAMTRGQNSLMIEPD
HHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEECCC
AEPRPNIGADGQVRERKPLSVRRAAPEEIAEHETVLAAIDKESKGACIWLPKPETEAA
CCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHEEECCCCCCCEEECCCCCCCCC
>Mature Secondary Structure
MRQIVLDTETTGLDPRSGHRIIEVACIEMVNRRFTGHHLHKYINPEREIDEGAQAVHGIT
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHCCC
LEFLADKPKFADIADEFLEFINGAELIIHNAPFDIGFLNAELDRLGRVPVGTICNGVIDT
EEECCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEHHHHHHHCCCCHHHHHHHHHHH
LRMAKELHPGKRNSLDALCERYEIDNSSRTLHGALLDTELLADVFLAMTRGQNSLMIEPD
HHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEECCC
AEPRPNIGADGQVRERKPLSVRRAAPEEIAEHETVLAAIDKESKGACIWLPKPETEAA
CCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHEEECCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]