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The map label for this gene is ureC

Identifier: 71907059

GI number: 71907059

Start: 1553493

End: 1555202

Strand: Reverse

Name: ureC

Synonym: Daro_1427

Alternate gene names: 71907059

Gene position: 1555202-1553493 (Counterclockwise)

Preceding gene: 71907060

Following gene: 71907058

Centisome position: 34.55

GC content: 65.03

Gene sequence:

>1710_bases
ATGATGGCAAACAAGATTACCCGTCAGGCCTATGCCGAAATGTTCGGCCCCACGACCGGCGACCGCATGCGCCTGGCAGA
CACCGAGCTGATCATCGAAGTCGAGAAGGACTACACGATCTACGGCGAGGAAGTGAAATTCGGCGGCGGCAAGGTCATCC
GCGACGGCATGGGCCAGGGCCAGCGCCTCTCGGCCGAAACGGTCGACACGGTCATCACCAATGCCCTGATCGTCGATGCC
GTGACCGGCATCGTCAAGGCCGACATCGGCTTGAAGGAAGGCCGCATCGCTGCCATCGGCAAGGCCGGCAACCCGGACAT
CCAGCCGGGCGTCACCATTGTCATCGGCCCCGGCACTGAAGTCATCGCCGGCGAAGGCATGATCGTCACGGCCGGCGGCA
TCGACAGCCACATCCATTTCATCTGCCCGCAGCAGATCGACGAGGCGCTGTATTCCGGTGTCACGACCATGATCGGTGGC
GGCACCGGGCCGGCGACCGGCACCTTCGCCACCACCTGCACGCCGGGGCCGTGGCATATCCACCGCATGCTGGAGGCGGC
CGACGCCTTCCCGATGAACCTCGGCTTCCTCGGCAAGGGCAACGCCAGCCTGCCGGAAGCCCTGCGCGAGCAGGTCGAAG
CCGGCGTCATGGGTTTGAAGCTGCATGAAGACTGGGGCACGACGCCGGCCGCCATCGACTGCTGCCTGACGGTGGCCGAC
GAAATGGACGTGCAGGTCGCCATCCACTCCGACACGCTCAACGAATCGGGCTTCGTCGAAGCGACGCTGGGCGCCTTCAA
GGGCCGCACCATCCACACCTTCCACACCGAAGGCGCCGGCGGCGGCCATGCGCCGGACATCATCAAGGCCGCTGGGCTGC
CCAATGTCCTGCCTAGCTCGACCAACCCAACCATGCCCTACACGGTGAACACCATCGACGAGCATCTCGACATGCTGATG
GTTTGCCACCACCTCGACCCGAGCATCGCCGAGGACATCGCCTTCGCCGAAAGCCGCATCCGCCGCGAAACCATCGCCGC
CGAAGACATCCTGCACGACCTTGGCGCCTTCTCGATGATGTCGTCCGACTCGCAGGCCATGGGCCGGGTCGGCGAGGTCA
TCATCCGCACCTGGCAGGCGGCGCACAAGATGAAGCTGCAGCGCGGCGCCTTGCCGGAAGACAGCGCCCGCAACGACAAC
TTCCGGGTCAAGCGCTACATCGCCAAATACACCATCAACCCGGCGCTGACCCACGGCATCGCCCACACCGTCGGCTCCGT
CGAAGTCGGCAAGCTGGCCGATCTGGTGCTTTGGAAGCCGGCCTTCTTCGGCGTCAAGCCGAGCCTGATCCTGAAGGGCG
GCATGATCGCCGCCGCCGCGATGGGCGATCCCAACGCCTCGATCCCGACGCCGCAGCCGGTGCATTACCGGCCAATGTTC
GGCAGCTTCGGCAAGGCGCTGAAAACCTCGGTCACCTTCATTTCGCAGGCGGCCCTGAACAATCCGGCCATTGCCGCGTT
GGGCTTGAGCAAGCCACTGGTCGCCGTCTCCGGCACGCGCACGCTGACCAAGGCCGACATGGTGCACAACGGCGCGACGC
CGGAAATCACCGTCGATCCCGAAACCTACGTGGTCAAGGCCGACGGCGTGCATCTCGTCTGCGAACCGGCCACCGAACTG
CCGCTAGCCCAACGCTACTTCCTGTTCTGA

Upstream 100 bases:

>100_bases
CCGTGCGCTTCGAGCCGGGCCAGACGCGGACCGTGCAACTGGTCGCGCTGGCCGGTGACCGCAAGGTCTATGGCTTCCGC
GGCCTCGTTCAGGGAGCACT

Downstream 100 bases:

>100_bases
CATGCTGATCCTGAACCAACGCACCCAACAACTCGCTACCGACTCGGTCGCCCTCGCCTACGACGAACGCAAACGCAGCC
GCCTGAAGGTCACGCTGGCC

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MMANKITRQAYAEMFGPTTGDRMRLADTELIIEVEKDYTIYGEEVKFGGGKVIRDGMGQGQRLSAETVDTVITNALIVDA
VTGIVKADIGLKEGRIAAIGKAGNPDIQPGVTIVIGPGTEVIAGEGMIVTAGGIDSHIHFICPQQIDEALYSGVTTMIGG
GTGPATGTFATTCTPGPWHIHRMLEAADAFPMNLGFLGKGNASLPEALREQVEAGVMGLKLHEDWGTTPAAIDCCLTVAD
EMDVQVAIHSDTLNESGFVEATLGAFKGRTIHTFHTEGAGGGHAPDIIKAAGLPNVLPSSTNPTMPYTVNTIDEHLDMLM
VCHHLDPSIAEDIAFAESRIRRETIAAEDILHDLGAFSMMSSDSQAMGRVGEVIIRTWQAAHKMKLQRGALPEDSARNDN
FRVKRYIAKYTINPALTHGIAHTVGSVEVGKLADLVLWKPAFFGVKPSLILKGGMIAAAAMGDPNASIPTPQPVHYRPMF
GSFGKALKTSVTFISQAALNNPAIAALGLSKPLVAVSGTRTLTKADMVHNGATPEITVDPETYVVKADGVHLVCEPATEL
PLAQRYFLF

Sequences:

>Translated_569_residues
MMANKITRQAYAEMFGPTTGDRMRLADTELIIEVEKDYTIYGEEVKFGGGKVIRDGMGQGQRLSAETVDTVITNALIVDA
VTGIVKADIGLKEGRIAAIGKAGNPDIQPGVTIVIGPGTEVIAGEGMIVTAGGIDSHIHFICPQQIDEALYSGVTTMIGG
GTGPATGTFATTCTPGPWHIHRMLEAADAFPMNLGFLGKGNASLPEALREQVEAGVMGLKLHEDWGTTPAAIDCCLTVAD
EMDVQVAIHSDTLNESGFVEATLGAFKGRTIHTFHTEGAGGGHAPDIIKAAGLPNVLPSSTNPTMPYTVNTIDEHLDMLM
VCHHLDPSIAEDIAFAESRIRRETIAAEDILHDLGAFSMMSSDSQAMGRVGEVIIRTWQAAHKMKLQRGALPEDSARNDN
FRVKRYIAKYTINPALTHGIAHTVGSVEVGKLADLVLWKPAFFGVKPSLILKGGMIAAAAMGDPNASIPTPQPVHYRPMF
GSFGKALKTSVTFISQAALNNPAIAALGLSKPLVAVSGTRTLTKADMVHNGATPEITVDPETYVVKADGVHLVCEPATEL
PLAQRYFLF
>Mature_569_residues
MMANKITRQAYAEMFGPTTGDRMRLADTELIIEVEKDYTIYGEEVKFGGGKVIRDGMGQGQRLSAETVDTVITNALIVDA
VTGIVKADIGLKEGRIAAIGKAGNPDIQPGVTIVIGPGTEVIAGEGMIVTAGGIDSHIHFICPQQIDEALYSGVTTMIGG
GTGPATGTFATTCTPGPWHIHRMLEAADAFPMNLGFLGKGNASLPEALREQVEAGVMGLKLHEDWGTTPAAIDCCLTVAD
EMDVQVAIHSDTLNESGFVEATLGAFKGRTIHTFHTEGAGGGHAPDIIKAAGLPNVLPSSTNPTMPYTVNTIDEHLDMLM
VCHHLDPSIAEDIAFAESRIRRETIAAEDILHDLGAFSMMSSDSQAMGRVGEVIIRTWQAAHKMKLQRGALPEDSARNDN
FRVKRYIAKYTINPALTHGIAHTVGSVEVGKLADLVLWKPAFFGVKPSLILKGGMIAAAAMGDPNASIPTPQPVHYRPMF
GSFGKALKTSVTFISQAALNNPAIAALGLSKPLVAVSGTRTLTKADMVHNGATPEITVDPETYVVKADGVHLVCEPATEL
PLAQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE1_DECAR (Q47G55)

Other databases:

- EMBL:   CP000089
- RefSeq:   YP_284646.1
- ProteinModelPortal:   Q47G55
- SMR:   Q47G55
- STRING:   Q47G55
- GeneID:   3569073
- GenomeReviews:   CP000089_GR
- KEGG:   dar:Daro_1427
- NMPDR:   fig|159087.4.peg.1280
- eggNOG:   COG0804
- HOGENOM:   HBG357507
- OMA:   TIHAFHT
- ProtClustDB:   PRK13207
- BioCyc:   DARO159087:DARO_1427-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01953
- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950
- PRINTS:   PR01752
- TIGRFAMs:   TIGR01792

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha; SSF51338 Metalo_hydrolase

EC number: =3.5.1.5

Molecular weight: Translated: 60410; Mature: 60410

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS01120 UREASE_1; PS00145 UREASE_2; PS51368 UREASE_3

Important sites: ACT_SITE 323-323 BINDING 222-222

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMANKITRQAYAEMFGPTTGDRMRLADTELIIEVEKDYTIYGEEVKFGGGKVIRDGMGQG
CCCHHHHHHHHHHHHCCCCCCCEEEECCEEEEEEECCEEEECCEEEECCCEEEECCCCCC
QRLSAETVDTVITNALIVDAVTGIVKADIGLKEGRIAAIGKAGNPDIQPGVTIVIGPGTE
CEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCC
VIAGEGMIVTAGGIDSHIHFICPQQIDEALYSGVTTMIGGGTGPATGTFATTCTPGPWHI
EEECCCEEEEECCCCCCEEEECHHHHHHHHHCCHHHEECCCCCCCCCCEEECCCCCHHHH
HRMLEAADAFPMNLGFLGKGNASLPEALREQVEAGVMGLKLHEDWGTTPAAIDCCLTVAD
HHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHCCC
EMDVQVAIHSDTLNESGFVEATLGAFKGRTIHTFHTEGAGGGHAPDIIKAAGLPNVLPSS
CCEEEEEEECCCCCCCCCEEEEHHHCCCCEEEEEECCCCCCCCCCHHHHHCCCCCCCCCC
TNPTMPYTVNTIDEHLDMLMVCHHLDPSIAEDIAFAESRIRRETIAAEDILHDLGAFSMM
CCCCCCEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSDSQAMGRVGEVIIRTWQAAHKMKLQRGALPEDSARNDNFRVKRYIAKYTINPALTHGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEEEEHHEECCHHHHHHH
AHTVGSVEVGKLADLVLWKPAFFGVKPSLILKGGMIAAAAMGDPNASIPTPQPVHYRPMF
HHHCCCCCHHHHHHHHEECCHHHCCCHHHEEECCEEEEEECCCCCCCCCCCCCCEECCCH
GSFGKALKTSVTFISQAALNNPAIAALGLSKPLVAVSGTRTLTKADMVHNGATPEITVDP
HHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCHHHHHHHHCCCCCCEEEECC
ETYVVKADGVHLVCEPATELPLAQRYFLF
CEEEEEECCEEEEECCCCCCCCCHHHHCC
>Mature Secondary Structure
MMANKITRQAYAEMFGPTTGDRMRLADTELIIEVEKDYTIYGEEVKFGGGKVIRDGMGQG
CCCHHHHHHHHHHHHCCCCCCCEEEECCEEEEEEECCEEEECCEEEECCCEEEECCCCCC
QRLSAETVDTVITNALIVDAVTGIVKADIGLKEGRIAAIGKAGNPDIQPGVTIVIGPGTE
CEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCC
VIAGEGMIVTAGGIDSHIHFICPQQIDEALYSGVTTMIGGGTGPATGTFATTCTPGPWHI
EEECCCEEEEECCCCCCEEEECHHHHHHHHHCCHHHEECCCCCCCCCCEEECCCCCHHHH
HRMLEAADAFPMNLGFLGKGNASLPEALREQVEAGVMGLKLHEDWGTTPAAIDCCLTVAD
HHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHCCC
EMDVQVAIHSDTLNESGFVEATLGAFKGRTIHTFHTEGAGGGHAPDIIKAAGLPNVLPSS
CCEEEEEEECCCCCCCCCEEEEHHHCCCCEEEEEECCCCCCCCCCHHHHHCCCCCCCCCC
TNPTMPYTVNTIDEHLDMLMVCHHLDPSIAEDIAFAESRIRRETIAAEDILHDLGAFSMM
CCCCCCEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSDSQAMGRVGEVIIRTWQAAHKMKLQRGALPEDSARNDNFRVKRYIAKYTINPALTHGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEEEEHHEECCHHHHHHH
AHTVGSVEVGKLADLVLWKPAFFGVKPSLILKGGMIAAAAMGDPNASIPTPQPVHYRPMF
HHHCCCCCHHHHHHHHEECCHHHCCCHHHEEECCEEEEEECCCCCCCCCCCCCCEECCCH
GSFGKALKTSVTFISQAALNNPAIAALGLSKPLVAVSGTRTLTKADMVHNGATPEITVDP
HHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCHHHHHHHHCCCCCCEEEECC
ETYVVKADGVHLVCEPATELPLAQRYFLF
CEEEEEECCEEEEECCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA