Click here to switch to the map view.

The map label for this gene is trxB [H]

Identifier: 71906928

GI number: 71906928

Start: 1402896

End: 1403858

Strand: Reverse

Name: trxB [H]

Synonym: Daro_1293

Alternate gene names: 71906928

Gene position: 1403858-1402896 (Counterclockwise)

Preceding gene: 71906932

Following gene: 71906927

Centisome position: 31.19

GC content: 60.33

Gene sequence:

>963_bases
ATGCCCCAGAATGTCCGCCACAATCCCCTCATCATCCTCGGTTCTGGCCCGGCCGGCTATACCGCTGCCGTCTATGCTGC
CCGCGCCAACCTCAAGCCGGTGCTGATCACCGGCATGGCTCAGGGCGGCCAGTTGATGACCACGACCGAAGTCGATAACT
GGCCAGCTGCCGCCGATGGCATTCAGGGTCCGGAATTGATGGCCAATTTCGAAGCCCATGCCCGTCGCTTCGAAACTGAA
ATCGTGTTCGACCATATCCACACCACCCAGCTGACCGAAAAGCCCTTCACGTTGATCGGCGATGCCGGCACCTACACCTG
CGACGCGCTGATCATCGCGACCGGCGCTTCTGCCATGTACCTTGGCCTGCCTTCCGAAGAAACCTTCGCCGGCAAGGGCG
TTTCGGCCTGTGCCACCTGCGACGGTTTCTTCTACCGCAACAAGCCGGTCGCCGTGGTCGGCGGTGGCAACACCGCTGTC
GAGGAAGCACTATACCTCGCCAATATTGCCAGCCATGTGACAGTGATTCACCGCCGCGAGAAGTTCAAGGCCGAGAAAAT
CATGCAGGACAAGCTCTTCCAGCGCGAAAAGGAAGGCAAGGTCACCATCCTCTGGAACAGCACACTGGACGAAGTACTCG
GCGACGACTCCGGCGTTACCGGCCTGTCGATCAAGAACGTGAAGAGCGGGGAAACCCAGAAGGTCGATGTGCACGGCGTC
TTCATCGCCATCGGCCACAAGCCGAATACCGACATTTTTGCTGGCCAACTGGAAATGGACAACGGCTACCTGGTCACTCA
GGCTGGCCGCAATGGCAACGCCACGCAAACCAGCATTCCCGGCATCTTCGCCGCTGGCGACGTGCAGGACCAGATCTACA
AGCAGGCCTGCACCTCGGCCGGCTCGGGCTGCATGGCAGCGCTCGATGCTGAGCGTTACCTGGACAACCTCGGTCACGCC
TGA

Upstream 100 bases:

>100_bases
ACAATTATAAACCGCTTTCCCAAATTACATAGGAACTTCGGAAAAATTGGAAGCTCAGACAACGCTATAATTTTCCGATC
AGTCACCCAAGAGGATCGTC

Downstream 100 bases:

>100_bases
ACCAACTTGATCGATCCGGAAGACCTCGCTGCCTTCCAGGCGGCAGTGGCCGACATCAAGCCACTGCCGCCGGTTAACCG
TGTTCATCTGACCAAACCGC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MPQNVRHNPLIILGSGPAGYTAAVYAARANLKPVLITGMAQGGQLMTTTEVDNWPAAADGIQGPELMANFEAHARRFETE
IVFDHIHTTQLTEKPFTLIGDAGTYTCDALIIATGASAMYLGLPSEETFAGKGVSACATCDGFFYRNKPVAVVGGGNTAV
EEALYLANIASHVTVIHRREKFKAEKIMQDKLFQREKEGKVTILWNSTLDEVLGDDSGVTGLSIKNVKSGETQKVDVHGV
FIAIGHKPNTDIFAGQLEMDNGYLVTQAGRNGNATQTSIPGIFAAGDVQDQIYKQACTSAGSGCMAALDAERYLDNLGHA

Sequences:

>Translated_320_residues
MPQNVRHNPLIILGSGPAGYTAAVYAARANLKPVLITGMAQGGQLMTTTEVDNWPAAADGIQGPELMANFEAHARRFETE
IVFDHIHTTQLTEKPFTLIGDAGTYTCDALIIATGASAMYLGLPSEETFAGKGVSACATCDGFFYRNKPVAVVGGGNTAV
EEALYLANIASHVTVIHRREKFKAEKIMQDKLFQREKEGKVTILWNSTLDEVLGDDSGVTGLSIKNVKSGETQKVDVHGV
FIAIGHKPNTDIFAGQLEMDNGYLVTQAGRNGNATQTSIPGIFAAGDVQDQIYKQACTSAGSGCMAALDAERYLDNLGHA
>Mature_319_residues
PQNVRHNPLIILGSGPAGYTAAVYAARANLKPVLITGMAQGGQLMTTTEVDNWPAAADGIQGPELMANFEAHARRFETEI
VFDHIHTTQLTEKPFTLIGDAGTYTCDALIIATGASAMYLGLPSEETFAGKGVSACATCDGFFYRNKPVAVVGGGNTAVE
EALYLANIASHVTVIHRREKFKAEKIMQDKLFQREKEGKVTILWNSTLDEVLGDDSGVTGLSIKNVKSGETQKVDVHGVF
IAIGHKPNTDIFAGQLEMDNGYLVTQAGRNGNATQTSIPGIFAAGDVQDQIYKQACTSAGSGCMAALDAERYLDNLGHA

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=316, Percent_Identity=65.5063291139241, Blast_Score=436, Evalue=1e-124,
Organism=Escherichia coli, GI87081763, Length=300, Percent_Identity=31.6666666666667, Blast_Score=150, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6320560, Length=323, Percent_Identity=48.9164086687306, Blast_Score=290, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6321898, Length=320, Percent_Identity=47.1875, Blast_Score=280, Evalue=3e-76,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34097; Mature: 33966

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQNVRHNPLIILGSGPAGYTAAVYAARANLKPVLITGMAQGGQLMTTTEVDNWPAAADG
CCCCCCCCCEEEEECCCCCCEEEEEEECCCCCEEEEEEECCCCEEEEEEECCCCCCCCCC
IQGPELMANFEAHARRFETEIVFDHIHTTQLTEKPFTLIGDAGTYTCDALIIATGASAMY
CCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEECCCCEEEEEEEEEECCCEEE
LGLPSEETFAGKGVSACATCDGFFYRNKPVAVVGGGNTAVEEALYLANIASHVTVIHRRE
EECCCCCCCCCCCCCCEEECCCEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
KFKAEKIMQDKLFQREKEGKVTILWNSTLDEVLGDDSGVTGLSIKNVKSGETQKVDVHGV
HHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCCEEEECCCCCCCEEEEEEEE
FIAIGHKPNTDIFAGQLEMDNGYLVTQAGRNGNATQTSIPGIFAAGDVQDQIYKQACTSA
EEEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCC
GSGCMAALDAERYLDNLGHA
CCCCEEEHHHHHHHHHHCCC
>Mature Secondary Structure 
PQNVRHNPLIILGSGPAGYTAAVYAARANLKPVLITGMAQGGQLMTTTEVDNWPAAADG
CCCCCCCCEEEEECCCCCCEEEEEEECCCCCEEEEEEECCCCEEEEEEECCCCCCCCCC
IQGPELMANFEAHARRFETEIVFDHIHTTQLTEKPFTLIGDAGTYTCDALIIATGASAMY
CCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEECCCCEEEEEEEEEECCCEEE
LGLPSEETFAGKGVSACATCDGFFYRNKPVAVVGGGNTAVEEALYLANIASHVTVIHRRE
EECCCCCCCCCCCCCCEEECCCEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
KFKAEKIMQDKLFQREKEGKVTILWNSTLDEVLGDDSGVTGLSIKNVKSGETQKVDVHGV
HHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCCEEEECCCCCCCEEEEEEEE
FIAIGHKPNTDIFAGQLEMDNGYLVTQAGRNGNATQTSIPGIFAAGDVQDQIYKQACTSA
EEEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCC
GSGCMAALDAERYLDNLGHA
CCCCEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]