Click here to switch to the map view.

The map label for this gene is exbB [H]

Identifier: 71906754

GI number: 71906754

Start: 1217756

End: 1218499

Strand: Reverse

Name: exbB [H]

Synonym: Daro_1115

Alternate gene names: 71906754

Gene position: 1218499-1217756 (Counterclockwise)

Preceding gene: 71906755

Following gene: 71906753

Centisome position: 27.07

GC content: 63.84

Gene sequence:

>744_bases
ATGCAGGAAACAGCACAAAATGCCTTCGGCTTTGCCCACCTTTGGGCCAGCGGTGACCTGATCTCCCATGCCATTGCCTG
CATTCTTGCCGTCATGTCGATCGCCAGCTGGTATCTGATTCTGGCCAAAGCCTGGGACTGGTTCCGGGCCCGCCGCGCCG
CCAAGGCCATGGCCGCTTTCTGGGCCGCCAGCAGTGTCAGCGAAGGCATCGAACAACTGCGCAAGGCAGGTGAAGACAGC
CCGTACGCCCAGTTGGCCACCCAGGCGAATTGCTGCAACCATGACTGCGAAGCGGTTACCGGCCGCCTGGCTTCCCGTTT
CGACCCAGCCGAGCAGATGGAACGCGCCCTGCGCCAGCAACTTTCCGCCACCCAGGCCCGGATGGAAAACGGCCTGACCC
TGCTCGCGACCACCGGTGCGACATCACCGTTCGTCGGTCTGTTCGGCACCGTCTGGGGCATTTATCACGCCTTGGTCGCC
ATCGGCATTTCCGGCCAGGCCGCGCTGGAAAAAATCGCCGGCCCGGTCGGCGAAGCGCTGATCATGACCGCTGCCGGCCT
CGCCGTTGCGTTGCCTGCCGTCTTTGCCTACAACGCCTTCACCCGCGCCAACCGTGTCCTATTGGCGGATCTCGACGCCT
TCGCCCACGATCTGCACGCCTTCTTCACGGTCGGCAAGCCATTTGTCGCCAACAGTGCGCAGATTCACCCGATGCGCGCC
CGCGCCGCCACGGAGGCTGCATAA

Upstream 100 bases:

>100_bases
GACCGTGCGCAACTGGAAATTTGTGCCAGCCAAACGAGGCGACACCGCCATCCAGAGCTGGGTACTGGTGCCCATCATTT
TCAAATTGGAGCAATAACAA

Downstream 100 bases:

>100_bases
CATGGCCATTGGTAGCTTCAGTTCGCAAAATCACCAGATGCCGACCGCCGAAATCAACATGACGCCGCTGGTGGACGTGA
TGTTGGTACTACTGATCATC

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MQETAQNAFGFAHLWASGDLISHAIACILAVMSIASWYLILAKAWDWFRARRAAKAMAAFWAASSVSEGIEQLRKAGEDS
PYAQLATQANCCNHDCEAVTGRLASRFDPAEQMERALRQQLSATQARMENGLTLLATTGATSPFVGLFGTVWGIYHALVA
IGISGQAALEKIAGPVGEALIMTAAGLAVALPAVFAYNAFTRANRVLLADLDAFAHDLHAFFTVGKPFVANSAQIHPMRA
RAATEAA

Sequences:

>Translated_247_residues
MQETAQNAFGFAHLWASGDLISHAIACILAVMSIASWYLILAKAWDWFRARRAAKAMAAFWAASSVSEGIEQLRKAGEDS
PYAQLATQANCCNHDCEAVTGRLASRFDPAEQMERALRQQLSATQARMENGLTLLATTGATSPFVGLFGTVWGIYHALVA
IGISGQAALEKIAGPVGEALIMTAAGLAVALPAVFAYNAFTRANRVLLADLDAFAHDLHAFFTVGKPFVANSAQIHPMRA
RAATEAA
>Mature_247_residues
MQETAQNAFGFAHLWASGDLISHAIACILAVMSIASWYLILAKAWDWFRARRAAKAMAAFWAASSVSEGIEQLRKAGEDS
PYAQLATQANCCNHDCEAVTGRLASRFDPAEQMERALRQQLSATQARMENGLTLLATTGATSPFVGLFGTVWGIYHALVA
IGISGQAALEKIAGPVGEALIMTAAGLAVALPAVFAYNAFTRANRVLLADLDAFAHDLHAFFTVGKPFVANSAQIHPMRA
RAATEAA

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=232, Percent_Identity=31.8965517241379, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789381, Length=196, Percent_Identity=30.1020408163265, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26311; Mature: 26311

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQETAQNAFGFAHLWASGDLISHAIACILAVMSIASWYLILAKAWDWFRARRAAKAMAAF
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WAASSVSEGIEQLRKAGEDSPYAQLATQANCCNHDCEAVTGRLASRFDPAEQMERALRQQ
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
LSATQARMENGLTLLATTGATSPFVGLFGTVWGIYHALVAIGISGQAALEKIAGPVGEAL
HHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IMTAAGLAVALPAVFAYNAFTRANRVLLADLDAFAHDLHAFFTVGKPFVANSAQIHPMRA
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHH
RAATEAA
HHHHCCC
>Mature Secondary Structure
MQETAQNAFGFAHLWASGDLISHAIACILAVMSIASWYLILAKAWDWFRARRAAKAMAAF
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WAASSVSEGIEQLRKAGEDSPYAQLATQANCCNHDCEAVTGRLASRFDPAEQMERALRQQ
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
LSATQARMENGLTLLATTGATSPFVGLFGTVWGIYHALVAIGISGQAALEKIAGPVGEAL
HHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IMTAAGLAVALPAVFAYNAFTRANRVLLADLDAFAHDLHAFFTVGKPFVANSAQIHPMRA
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHH
RAATEAA
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]