Click here to switch to the map view.

The map label for this gene is corA [H]

Identifier: 71906720

GI number: 71906720

Start: 1185654

End: 1186619

Strand: Reverse

Name: corA [H]

Synonym: Daro_1081

Alternate gene names: 71906720

Gene position: 1186619-1185654 (Counterclockwise)

Preceding gene: 71906721

Following gene: 71906719

Centisome position: 26.36

GC content: 56.31

Gene sequence:

>966_bases
ATGCTGATCAATTGTGTTGCCTATGAGAACGGCTCGCGCCTGGCCGACTTGGCAGTTGAGGAAATCAGCGACTATCTGGC
CAAACCGGATTGCTTCGTCTGGGTAGCCCTACGCGATGCAACACTGCAAGAGCTCGACAAGATGAAGGAAGAGTTCTCGC
TGCACGAACTGGCCGTGGAGGATGCTCGCCATGGTCACCAGCGACCGAAGATCGAGGAGTATGGTGATTCGGTATTCGCC
GTCATGCACCTACTCGAAGATGACAAGGGCGAGTTCAATATCGGGGAGGTCAATGTCTTCGTCGGTCAGAACTACATTCT
GTCGGTCAGAAACCATAGCCAGCAGCATTTTCTCGGGGTGCGCGAACGCTGCGAGCGGGAGCCGCACCTGCTCAGTCACG
GGGCGGGCTTCGTCCTCTATGCCCTGATGGATGCAGTCGTCGATCGCTACTTTCCGATCATGGACCGGCTGGAGTCGGAA
CTCGAAGAAATCGAGGAGCAGATCTTTACCAAGGGCGCCGCCCGCAGCAATATCGAGCGGCTTTACGACCTGAAGCGCAA
GATTACTTTGCTCAAGCATGCCGTCGCGCCAATGATGGAGGCCACTGGCAAGCTTTCAGGTGGCCGTGGGCCGGCAGTCT
GTGCCAACAGCCGGGATTACTTTCGCGATGTCTATGATCACCTCGCGCGGATCAACGCCTCGCTGGATACGATCAGGGAC
ACCATTGGTACCGCCATTCAGGTCAACCTGTCCATGGTGACCATTGAAGAAAGCGAAGTGAACAAGAAGCTGGCGGCATG
GGCTGGTATTTTTGCCATCGCCACCGCTTTTGCCGGCATCTGGGGAATGAACTTCAAGGCAATGCCCGAACTGCAATGGG
AGTACGGTTACCCGATGGCGCTTCTGACCATCAGCGCGGCCTGTGTTGCGCTATATGTCCACTTCAGACGCGTCGGCTGG
CTATAA

Upstream 100 bases:

>100_bases
ACTGCAAGTCGGTCTTCCCGGGGTTGATTCGGGCGCGCGTGCTCGCTGAAATGGCTAAAAGCGTGCAGGATAGGGTTGTC
GAAACGCAGGGGGATATTGA

Downstream 100 bases:

>100_bases
GGATGGATTGATGGCTGATCAAAGACCCGACCCCGATCAACTGCTCAACCGCGTGAATGCGGAAGAAGCCAGGTCCAAAC
GCGGCAAGCTGAAGATATTT

Product: magnesium/cobalt transporter CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MLINCVAYENGSRLADLAVEEISDYLAKPDCFVWVALRDATLQELDKMKEEFSLHELAVEDARHGHQRPKIEEYGDSVFA
VMHLLEDDKGEFNIGEVNVFVGQNYILSVRNHSQQHFLGVRERCEREPHLLSHGAGFVLYALMDAVVDRYFPIMDRLESE
LEEIEEQIFTKGAARSNIERLYDLKRKITLLKHAVAPMMEATGKLSGGRGPAVCANSRDYFRDVYDHLARINASLDTIRD
TIGTAIQVNLSMVTIEESEVNKKLAAWAGIFAIATAFAGIWGMNFKAMPELQWEYGYPMALLTISAACVALYVHFRRVGW
L

Sequences:

>Translated_321_residues
MLINCVAYENGSRLADLAVEEISDYLAKPDCFVWVALRDATLQELDKMKEEFSLHELAVEDARHGHQRPKIEEYGDSVFA
VMHLLEDDKGEFNIGEVNVFVGQNYILSVRNHSQQHFLGVRERCEREPHLLSHGAGFVLYALMDAVVDRYFPIMDRLESE
LEEIEEQIFTKGAARSNIERLYDLKRKITLLKHAVAPMMEATGKLSGGRGPAVCANSRDYFRDVYDHLARINASLDTIRD
TIGTAIQVNLSMVTIEESEVNKKLAAWAGIFAIATAFAGIWGMNFKAMPELQWEYGYPMALLTISAACVALYVHFRRVGW
L
>Mature_321_residues
MLINCVAYENGSRLADLAVEEISDYLAKPDCFVWVALRDATLQELDKMKEEFSLHELAVEDARHGHQRPKIEEYGDSVFA
VMHLLEDDKGEFNIGEVNVFVGQNYILSVRNHSQQHFLGVRERCEREPHLLSHGAGFVLYALMDAVVDRYFPIMDRLESE
LEEIEEQIFTKGAARSNIERLYDLKRKITLLKHAVAPMMEATGKLSGGRGPAVCANSRDYFRDVYDHLARINASLDTIRD
TIGTAIQVNLSMVTIEESEVNKKLAAWAGIFAIATAFAGIWGMNFKAMPELQWEYGYPMALLTISAACVALYVHFRRVGW
L

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=119, Percent_Identity=31.0924369747899, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36351; Mature: 36351

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLINCVAYENGSRLADLAVEEISDYLAKPDCFVWVALRDATLQELDKMKEEFSLHELAVE
CEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
DARHGHQRPKIEEYGDSVFAVMHLLEDDKGEFNIGEVNVFVGQNYILSVRNHSQQHFLGV
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECEEEEEECCCEEEEECCCCHHHHHHH
RERCEREPHLLSHGAGFVLYALMDAVVDRYFPIMDRLESELEEIEEQIFTKGAARSNIER
HHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LYDLKRKITLLKHAVAPMMEATGKLSGGRGPAVCANSRDYFRDVYDHLARINASLDTIRD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHH
TIGTAIQVNLSMVTIEESEVNKKLAAWAGIFAIATAFAGIWGMNFKAMPELQWEYGYPMA
HHCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
LLTISAACVALYVHFRRVGWL
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLINCVAYENGSRLADLAVEEISDYLAKPDCFVWVALRDATLQELDKMKEEFSLHELAVE
CEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
DARHGHQRPKIEEYGDSVFAVMHLLEDDKGEFNIGEVNVFVGQNYILSVRNHSQQHFLGV
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECEEEEEECCCEEEEECCCCHHHHHHH
RERCEREPHLLSHGAGFVLYALMDAVVDRYFPIMDRLESELEEIEEQIFTKGAARSNIER
HHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LYDLKRKITLLKHAVAPMMEATGKLSGGRGPAVCANSRDYFRDVYDHLARINASLDTIRD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHH
TIGTAIQVNLSMVTIEESEVNKKLAAWAGIFAIATAFAGIWGMNFKAMPELQWEYGYPMA
HHCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
LLTISAACVALYVHFRRVGWL
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]