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The map label for this gene is exaA [H]

Identifier: 71906662

GI number: 71906662

Start: 1122926

End: 1124707

Strand: Reverse

Name: exaA [H]

Synonym: Daro_1023

Alternate gene names: 71906662

Gene position: 1124707-1122926 (Counterclockwise)

Preceding gene: 71906663

Following gene: 71906661

Centisome position: 24.99

GC content: 64.03

Gene sequence:

>1782_bases
ATGCACAGTCATACCCCCAAGCGGAGTGCCCTCACACTTGCGCTGATCGCCGCCGCCGTTCTGGCCGGCGGGCAGGCTCT
GGCCGGCGTCACCGATGCCGACATCCTGAACGATGCCAAGACCACCGGCGACGTCGTCAGCTTTGGCCTCGGCACGCAGG
GCCAACGCTTCAGCCCGTCTACGCAGATCAACACCAAATCCGTGAAGAACCTGGTCCCGGCCTGGTCGATGTCCTTCGGC
GGCGAGAAGCAGCGCGGCCAGGAATCGCAGCCGGTCATCCACGACGGCAAGATGTTCGTCACCGCCTCCTACAGCCGCCT
GTTCGCCATCGATGCGAAGACCGGCAAGAAGCTGTGGAAGTACGAGCACCGTCTGCCGGACGGCATCATGCCCTGCTGTG
ACGTGATCAATCGCGGCGCCGCGCTGTACGGCGACCTGGTCATCTTCGCCACGCTGGATGCCCAACTCGTGGCCATGAAC
CAGAATACCGGCAAGGTCGTCTGGAAGGAAAAGCTCGGCGATTACGCGGCCGGCTATTCCGCCTCCGCCGCCCCGATCAT
TGCCAAGGGCAAGCTGATCACGGGCATCTCCGGTGGCGAATTCGGCGCTGTCGGCCGCATTGACGCCCGCGACCCGCTGA
CCGGCAAGCTGCTGTGGACCCGTCCGACCGTCGAAGGCCACATGGGCTATCGCTACGACGCCGACGGCAAGGCTATCGAA
AACGGCATCTCCGGCACCCTCAACGCCACCTGGAGCGGCGACCTCTGGCAAACTGGCGGCGCAGCAACCTGGAACGGCGC
CACCTACGATCCGGAAACCAACCTGATCTTCGCCGGCACCGGCAATCCGGCCCCGTGGAACAGCCACCTGCGCCCGGGCG
ACAACCTGTTCTCGTCGTCCACCGTTGCCATCGATGCCGACACCGGCAAGATCGCCTGGCACTTCCAGGGCACCCCGCAC
GACGGCTGGGACTTTGACGGCGTTAACGAGTTCGTCTCCTTTGACCTCAAGGACCCGAAGACCGGCAAGATCGTCAAGGC
AGGTGCAAAGGCTGACCGCAACGGCTTCTTCTTCGTGAACGACCGCACCAACGGCAAGCTGCTCGGCGCCTACCCGTTCG
TCAAGAAGATCACCTGGGCTACCGGCTTCAACCTCGAAACCGGCCGTCCGAACTACATCGAAGAAGGCCGTCCGGGCGAC
CCGAACGCCAGTGCCGATGGCAAGAAGGGCAAGGTCGTCTTCTCGGCTCCGTCCTTCCTCGGCGGCAAGAACCAGCAACA
AATGGCCTACAGCCCGCAAACCGGCCTCTTCTACGTGCCGGCCAACGAGTGGTCGATGGATATCTGGAACGAACCCGTTT
CCTACAAGAAAGGTGCGGCTTACCTCGGCGCCGGCTTCACCATCAAGGCTCTGAACGACGACTACATCGGCGCCCTGCGC
GCGGTCGACCCGGCTACCGGCAAGATCGTCTGGGAAAACAAGAACTACGCTCCGCTGTGGGGCGGCGTCCTGACCACCGC
CGGCGGCCTCGTCTTCTACGGCACCCCCGAAGGCTTCCTGAAGGGTGTCGATGCCAAGACCGGCAAGGAACTGTGGTCCT
TCAACGTCGGCACCGGCATCGTTGCACCACCGGTCAGTTGGGAGCAGGATGGCGAGCAGATGATCGCCGTCACGACCGGC
TGGGGCGGCGCCGTGCCGCTGTGGGGCGGCGACGTCGCCAAGCGCGTGAACTTCCTCGAACAGGGCGGTTCCGTCTGGGT
CTTCAAGCTGCACAAGGGCTAA

Upstream 100 bases:

>100_bases
GGAAAGGAAGGCGACTCGCCGGTGCGTCAGTCCAATCCGCAGCCCACGCCCAGCGCGGCCGGCGGATCAGGAAACATTGG
ATAACCAAGGAGACAAATCC

Downstream 100 bases:

>100_bases
ACGCATCACCATGCCGGGCCGCTTCAGCGGTCCGGCATTTCATGTCTCAATCCATACCCATAACGGAGAACATCCATGTT
CCGTCACCGCAAACTCATCG

Product: Pyrrolo-quinoline quinone

Products: NA

Alternate protein names: QEDH [H]

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MHSHTPKRSALTLALIAAAVLAGGQALAGVTDADILNDAKTTGDVVSFGLGTQGQRFSPSTQINTKSVKNLVPAWSMSFG
GEKQRGQESQPVIHDGKMFVTASYSRLFAIDAKTGKKLWKYEHRLPDGIMPCCDVINRGAALYGDLVIFATLDAQLVAMN
QNTGKVVWKEKLGDYAAGYSASAAPIIAKGKLITGISGGEFGAVGRIDARDPLTGKLLWTRPTVEGHMGYRYDADGKAIE
NGISGTLNATWSGDLWQTGGAATWNGATYDPETNLIFAGTGNPAPWNSHLRPGDNLFSSSTVAIDADTGKIAWHFQGTPH
DGWDFDGVNEFVSFDLKDPKTGKIVKAGAKADRNGFFFVNDRTNGKLLGAYPFVKKITWATGFNLETGRPNYIEEGRPGD
PNASADGKKGKVVFSAPSFLGGKNQQQMAYSPQTGLFYVPANEWSMDIWNEPVSYKKGAAYLGAGFTIKALNDDYIGALR
AVDPATGKIVWENKNYAPLWGGVLTTAGGLVFYGTPEGFLKGVDAKTGKELWSFNVGTGIVAPPVSWEQDGEQMIAVTTG
WGGAVPLWGGDVAKRVNFLEQGGSVWVFKLHKG

Sequences:

>Translated_593_residues
MHSHTPKRSALTLALIAAAVLAGGQALAGVTDADILNDAKTTGDVVSFGLGTQGQRFSPSTQINTKSVKNLVPAWSMSFG
GEKQRGQESQPVIHDGKMFVTASYSRLFAIDAKTGKKLWKYEHRLPDGIMPCCDVINRGAALYGDLVIFATLDAQLVAMN
QNTGKVVWKEKLGDYAAGYSASAAPIIAKGKLITGISGGEFGAVGRIDARDPLTGKLLWTRPTVEGHMGYRYDADGKAIE
NGISGTLNATWSGDLWQTGGAATWNGATYDPETNLIFAGTGNPAPWNSHLRPGDNLFSSSTVAIDADTGKIAWHFQGTPH
DGWDFDGVNEFVSFDLKDPKTGKIVKAGAKADRNGFFFVNDRTNGKLLGAYPFVKKITWATGFNLETGRPNYIEEGRPGD
PNASADGKKGKVVFSAPSFLGGKNQQQMAYSPQTGLFYVPANEWSMDIWNEPVSYKKGAAYLGAGFTIKALNDDYIGALR
AVDPATGKIVWENKNYAPLWGGVLTTAGGLVFYGTPEGFLKGVDAKTGKELWSFNVGTGIVAPPVSWEQDGEQMIAVTTG
WGGAVPLWGGDVAKRVNFLEQGGSVWVFKLHKG
>Mature_593_residues
MHSHTPKRSALTLALIAAAVLAGGQALAGVTDADILNDAKTTGDVVSFGLGTQGQRFSPSTQINTKSVKNLVPAWSMSFG
GEKQRGQESQPVIHDGKMFVTASYSRLFAIDAKTGKKLWKYEHRLPDGIMPCCDVINRGAALYGDLVIFATLDAQLVAMN
QNTGKVVWKEKLGDYAAGYSASAAPIIAKGKLITGISGGEFGAVGRIDARDPLTGKLLWTRPTVEGHMGYRYDADGKAIE
NGISGTLNATWSGDLWQTGGAATWNGATYDPETNLIFAGTGNPAPWNSHLRPGDNLFSSSTVAIDADTGKIAWHFQGTPH
DGWDFDGVNEFVSFDLKDPKTGKIVKAGAKADRNGFFFVNDRTNGKLLGAYPFVKKITWATGFNLETGRPNYIEEGRPGD
PNASADGKKGKVVFSAPSFLGGKNQQQMAYSPQTGLFYVPANEWSMDIWNEPVSYKKGAAYLGAGFTIKALNDDYIGALR
AVDPATGKIVWENKNYAPLWGGVLTTAGGLVFYGTPEGFLKGVDAKTGKELWSFNVGTGIVAPPVSWEQDGEQMIAVTTG
WGGAVPLWGGDVAKRVNFLEQGGSVWVFKLHKG

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is a very poor substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=364, Percent_Identity=26.9230769230769, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 63411; Mature: 63411

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSHTPKRSALTLALIAAAVLAGGQALAGVTDADILNDAKTTGDVVSFGLGTQGQRFSPS
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCEEEECCCCCCCCCCCC
TQINTKSVKNLVPAWSMSFGGEKQRGQESQPVIHDGKMFVTASYSRLFAIDAKTGKKLWK
CCCCHHHHHHHCCCCCCCCCCCHHCCCCCCCEEECCEEEEEEECEEEEEEECCCCHHHHH
YEHRLPDGIMPCCDVINRGAALYGDLVIFATLDAQLVAMNQNTGKVVWKEKLGDYAAGYS
HHHCCCCCHHHHHHHHHCCCCHHCCEEEEEECCEEEEEEECCCCCEEEHHHCCCHHCCCC
ASAAPIIAKGKLITGISGGEFGAVGRIDARDPLTGKLLWTRPTVEGHMGYRYDADGKAIE
CCCCCEEECCEEEEECCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCCEEECCCCHHHH
NGISGTLNATWSGDLWQTGGAATWNGATYDPETNLIFAGTGNPAPWNSHLRPGDNLFSSS
CCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
TVAIDADTGKIAWHFQGTPHDGWDFDGVNEFVSFDLKDPKTGKIVKAGAKADRNGFFFVN
EEEEECCCCEEEEEECCCCCCCCCCCCCCHHEEECCCCCCCCCEEEECCCCCCCCEEEEE
DRTNGKLLGAYPFVKKITWATGFNLETGRPNYIEEGRPGDPNASADGKKGKVVFSAPSFL
CCCCCEEEECCHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHC
GGKNQQQMAYSPQTGLFYVPANEWSMDIWNEPVSYKKGAAYLGAGFTIKALNDDYIGALR
CCCCCCCEEECCCCCEEEEECCCCCHHHCCCCCCCCCCCEEEECCEEEEECCCCHHEEEE
AVDPATGKIVWENKNYAPLWGGVLTTAGGLVFYGTPEGFLKGVDAKTGKELWSFNVGTGI
ECCCCCCEEEECCCCCCCCCCCHHHHCCCEEEEECCHHHHCCCCCCCCCHHEEEECCCCC
VAPPVSWEQDGEQMIAVTTGWGGAVPLWGGDVAKRVNFLEQGGSVWVFKLHKG
EECCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECC
>Mature Secondary Structure
MHSHTPKRSALTLALIAAAVLAGGQALAGVTDADILNDAKTTGDVVSFGLGTQGQRFSPS
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCEEEECCCCCCCCCCCC
TQINTKSVKNLVPAWSMSFGGEKQRGQESQPVIHDGKMFVTASYSRLFAIDAKTGKKLWK
CCCCHHHHHHHCCCCCCCCCCCHHCCCCCCCEEECCEEEEEEECEEEEEEECCCCHHHHH
YEHRLPDGIMPCCDVINRGAALYGDLVIFATLDAQLVAMNQNTGKVVWKEKLGDYAAGYS
HHHCCCCCHHHHHHHHHCCCCHHCCEEEEEECCEEEEEEECCCCCEEEHHHCCCHHCCCC
ASAAPIIAKGKLITGISGGEFGAVGRIDARDPLTGKLLWTRPTVEGHMGYRYDADGKAIE
CCCCCEEECCEEEEECCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCCEEECCCCHHHH
NGISGTLNATWSGDLWQTGGAATWNGATYDPETNLIFAGTGNPAPWNSHLRPGDNLFSSS
CCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
TVAIDADTGKIAWHFQGTPHDGWDFDGVNEFVSFDLKDPKTGKIVKAGAKADRNGFFFVN
EEEEECCCCEEEEEECCCCCCCCCCCCCCHHEEECCCCCCCCCEEEECCCCCCCCEEEEE
DRTNGKLLGAYPFVKKITWATGFNLETGRPNYIEEGRPGDPNASADGKKGKVVFSAPSFL
CCCCCEEEECCHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHC
GGKNQQQMAYSPQTGLFYVPANEWSMDIWNEPVSYKKGAAYLGAGFTIKALNDDYIGALR
CCCCCCCEEECCCCCEEEEECCCCCHHHCCCCCCCCCCCEEEECCEEEEECCCCHHEEEE
AVDPATGKIVWENKNYAPLWGGVLTTAGGLVFYGTPEGFLKGVDAKTGKELWSFNVGTGI
ECCCCCCEEEECCCCCCCCCCCHHHHCCCEEEEECCHHHHCCCCCCCCCHHEEEECCCCC
VAPPVSWEQDGEQMIAVTTGWGGAVPLWGGDVAKRVNFLEQGGSVWVFKLHKG
EECCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9826187; 10984043; 10075429; 10736230 [H]