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The map label for this gene is aer [H]

Identifier: 71906313

GI number: 71906313

Start: 742204

End: 743838

Strand: Reverse

Name: aer [H]

Synonym: Daro_0674

Alternate gene names: 71906313

Gene position: 743838-742204 (Counterclockwise)

Preceding gene: 71906314

Following gene: 71906307

Centisome position: 16.53

GC content: 65.32

Gene sequence:

>1635_bases
ATGCGTAACAACCAGCCTGTCACGGACGTCGAAACACGCTTGCCGGAGGGCCAGTTCATCTACTCCCGCACCGACCTCAA
GGGGGTCATCACCGAAGCCAACGAGGCCTTCGCCCAGATCAGCGCCTACCGGCGTGAAGAGATGCTGGGCGAAAACCACA
ACATGGTGCGACATCCGGACATGCCGGCCGCCGCCTTTGCCGACATGTGGAACGATCTCCGCGCGGGCCGCCCCTGGCGC
GGCGTGGTCAAGAACCGGCGCCGGGATGGCGGCTACTACTGGGTGCTCGCCAATGCCTCGCCGATCCGCGAACACGGGCA
GATCGTCGGTTACCAGTCGGTCCGGACCGCCCCCGGCCGCGAGGAAATCAAGGCGGCAGAAAACGCCTACCAGCGTATCC
GCCAGGGCGACACGTCGATCGCCGTCAAGCACGGCCGGGTCGTCGCCGCCCGAAAATCCCTGCTCACCCGTTTTACCGGT
CTCGGCTTCCAGTTGCCGTTGATGGGCATCCTCGGCTGTTTGCTCGGCCTGTCCGCGCTGCTAGCCAGCCTGCACCCGGA
CCCGGCACTGGCTCCGCTGCACCTGACGGCAGGCGGCATCGGCATCCTGCTCAGCCTCAACTACCTGCTCGTCTTCGCGC
CGCGCCTGAAAAACGACCTCGGCGATACCTTCGCCGCGCTCGACAAGATGCTGACCAGCGGCGACCTGCGCCAGCGCATC
GAGCATCGTCGGCACGATCTGGTCGGCGACATGGTCGGCCACATTGACCGCGTCATTTCCTCCTTCCAATCCACCGTCCA
GGGCATGGCCGACACCGCTTCGCACGTGCATCGCGTCGCTGGCGAAGTCAGGGAAGGCGTCGGCAATGTCCGCGAGGCGG
CCCGCGTGCAGAGCGATGCCACGGCCACTGCCGCCGCCGGCATCGAGCAGATTACCGTCTCGATCGGTGAGGTCGCCACC
CATGCCGGCTCGACGCGCGAGGCAGCCGCCCAGGCTTCGGCGCTATCCGAGGAAGGGGCCCGGCTGTCGTCCGAGGCGTG
CAGTACCATCCTGTCGCTGGCCGAAACGGTCAAGGGATCGGCCGTTCAGGTCGAGCTTCTGGGCCAGCAATCGGAAGAAA
TCTCGCGCATCACCGCCGTCATCAAGGGCATTGCCGACCAGACCAACCTGCTGGCGCTCAATGCCGCCATCGAGGCCGCC
CGCGCCGGGGATGCCGGCCGCGGCTTTTCGGTGGTCGCCGACGAAGTCCGCAAGCTGGCCGAAAGCACAGCCAAGGCGAC
CGGCGAGATCGCCGCGATGACCCTATCCGTGCAAGTCGAAACCGGCAAGGCGGTGAACTCCATGCGCCAGGGTGCCCAGC
AGGTCGAGAGCGGCGTCCAGCTTGTCCATGAGGCGCAAAACGCCCTGCAGGAAATCAATGCCCAGATGAACCTGACCGTC
GGCATGGTCAACGACATCTCCCACTCCTCCATCGAACAGGAGCAGGGCATGACCGTGATGGCGCAAAGCGTTGAGCGGGT
GGCCGCCATGACCGAGCAAAACATGGCCGTGGTCAGCCAGACGACGAATACGACCGACTATCTGGCCGAACTGGCCGAGC
GGATGAACAAGGCGGTCAACCAGTACATGATCTAG

Upstream 100 bases:

>100_bases
GCGGAAAGGTTCATCCGCAACAATCCGCCGATGAAGGGCCTCGGGACCATTGACCTGTGGCCAGCCCAGGAACAACTCAC
CCCAATCGAAGAGCACTGCC

Downstream 100 bases:

>100_bases
CCGATCAGGATCAGATGCACCCGACACGGGCCGTGGGCACCGAGGACGATGGTTTGCTCAATATCGCCGGTGCGTGACGG
GCCGGAAATGAAATTGACGG

Product: PAS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MRNNQPVTDVETRLPEGQFIYSRTDLKGVITEANEAFAQISAYRREEMLGENHNMVRHPDMPAAAFADMWNDLRAGRPWR
GVVKNRRRDGGYYWVLANASPIREHGQIVGYQSVRTAPGREEIKAAENAYQRIRQGDTSIAVKHGRVVAARKSLLTRFTG
LGFQLPLMGILGCLLGLSALLASLHPDPALAPLHLTAGGIGILLSLNYLLVFAPRLKNDLGDTFAALDKMLTSGDLRQRI
EHRRHDLVGDMVGHIDRVISSFQSTVQGMADTASHVHRVAGEVREGVGNVREAARVQSDATATAAAGIEQITVSIGEVAT
HAGSTREAAAQASALSEEGARLSSEACSTILSLAETVKGSAVQVELLGQQSEEISRITAVIKGIADQTNLLALNAAIEAA
RAGDAGRGFSVVADEVRKLAESTAKATGEIAAMTLSVQVETGKAVNSMRQGAQQVESGVQLVHEAQNALQEINAQMNLTV
GMVNDISHSSIEQEQGMTVMAQSVERVAAMTEQNMAVVSQTTNTTDYLAELAERMNKAVNQYMI

Sequences:

>Translated_544_residues
MRNNQPVTDVETRLPEGQFIYSRTDLKGVITEANEAFAQISAYRREEMLGENHNMVRHPDMPAAAFADMWNDLRAGRPWR
GVVKNRRRDGGYYWVLANASPIREHGQIVGYQSVRTAPGREEIKAAENAYQRIRQGDTSIAVKHGRVVAARKSLLTRFTG
LGFQLPLMGILGCLLGLSALLASLHPDPALAPLHLTAGGIGILLSLNYLLVFAPRLKNDLGDTFAALDKMLTSGDLRQRI
EHRRHDLVGDMVGHIDRVISSFQSTVQGMADTASHVHRVAGEVREGVGNVREAARVQSDATATAAAGIEQITVSIGEVAT
HAGSTREAAAQASALSEEGARLSSEACSTILSLAETVKGSAVQVELLGQQSEEISRITAVIKGIADQTNLLALNAAIEAA
RAGDAGRGFSVVADEVRKLAESTAKATGEIAAMTLSVQVETGKAVNSMRQGAQQVESGVQLVHEAQNALQEINAQMNLTV
GMVNDISHSSIEQEQGMTVMAQSVERVAAMTEQNMAVVSQTTNTTDYLAELAERMNKAVNQYMI
>Mature_544_residues
MRNNQPVTDVETRLPEGQFIYSRTDLKGVITEANEAFAQISAYRREEMLGENHNMVRHPDMPAAAFADMWNDLRAGRPWR
GVVKNRRRDGGYYWVLANASPIREHGQIVGYQSVRTAPGREEIKAAENAYQRIRQGDTSIAVKHGRVVAARKSLLTRFTG
LGFQLPLMGILGCLLGLSALLASLHPDPALAPLHLTAGGIGILLSLNYLLVFAPRLKNDLGDTFAALDKMLTSGDLRQRI
EHRRHDLVGDMVGHIDRVISSFQSTVQGMADTASHVHRVAGEVREGVGNVREAARVQSDATATAAAGIEQITVSIGEVAT
HAGSTREAAAQASALSEEGARLSSEACSTILSLAETVKGSAVQVELLGQQSEEISRITAVIKGIADQTNLLALNAAIEAA
RAGDAGRGFSVVADEVRKLAESTAKATGEIAAMTLSVQVETGKAVNSMRQGAQQVESGVQLVHEAQNALQEINAQMNLTV
GMVNDISHSSIEQEQGMTVMAQSVERVAAMTEQNMAVVSQTTNTTDYLAELAERMNKAVNQYMI

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=540, Percent_Identity=31.2962962962963, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI1787690, Length=312, Percent_Identity=29.4871794871795, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788194, Length=297, Percent_Identity=31.3131313131313, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788195, Length=298, Percent_Identity=29.8657718120805, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI2367378, Length=284, Percent_Identity=28.8732394366197, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 58493; Mature: 58493

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNNQPVTDVETRLPEGQFIYSRTDLKGVITEANEAFAQISAYRREEMLGENHNMVRHPD
CCCCCCCCHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
MPAAAFADMWNDLRAGRPWRGVVKNRRRDGGYYWVLANASPIREHGQIVGYQSVRTAPGR
CCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEECCCCHHHCCCEECCHHHCCCCCH
EEIKAAENAYQRIRQGDTSIAVKHGRVVAARKSLLTRFTGLGFQLPLMGILGCLLGLSAL
HHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LASLHPDPALAPLHLTAGGIGILLSLNYLLVFAPRLKNDLGDTFAALDKMLTSGDLRQRI
HHHCCCCCCCCCEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
EHRRHDLVGDMVGHIDRVISSFQSTVQGMADTASHVHRVAGEVREGVGNVREAARVQSDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TATAAAGIEQITVSIGEVATHAGSTREAAAQASALSEEGARLSSEACSTILSLAETVKGS
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
AVQVELLGQQSEEISRITAVIKGIADQTNLLALNAAIEAARAGDAGRGFSVVADEVRKLA
CEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ESTAKATGEIAAMTLSVQVETGKAVNSMRQGAQQVESGVQLVHEAQNALQEINAQMNLTV
HHHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEE
GMVNDISHSSIEQEQGMTVMAQSVERVAAMTEQNMAVVSQTTNTTDYLAELAERMNKAVN
EEHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHH
QYMI
HCCC
>Mature Secondary Structure
MRNNQPVTDVETRLPEGQFIYSRTDLKGVITEANEAFAQISAYRREEMLGENHNMVRHPD
CCCCCCCCHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
MPAAAFADMWNDLRAGRPWRGVVKNRRRDGGYYWVLANASPIREHGQIVGYQSVRTAPGR
CCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEECCCCHHHCCCEECCHHHCCCCCH
EEIKAAENAYQRIRQGDTSIAVKHGRVVAARKSLLTRFTGLGFQLPLMGILGCLLGLSAL
HHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LASLHPDPALAPLHLTAGGIGILLSLNYLLVFAPRLKNDLGDTFAALDKMLTSGDLRQRI
HHHCCCCCCCCCEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
EHRRHDLVGDMVGHIDRVISSFQSTVQGMADTASHVHRVAGEVREGVGNVREAARVQSDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TATAAAGIEQITVSIGEVATHAGSTREAAAQASALSEEGARLSSEACSTILSLAETVKGS
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
AVQVELLGQQSEEISRITAVIKGIADQTNLLALNAAIEAARAGDAGRGFSVVADEVRKLA
CEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ESTAKATGEIAAMTLSVQVETGKAVNSMRQGAQQVESGVQLVHEAQNALQEINAQMNLTV
HHHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEE
GMVNDISHSSIEQEQGMTVMAQSVERVAAMTEQNMAVVSQTTNTTDYLAELAERMNKAVN
EEHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHH
QYMI
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]