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The map label for this gene is cobP [H]

Identifier: 71905789

GI number: 71905789

Start: 161356

End: 161922

Strand: Reverse

Name: cobP [H]

Synonym: Daro_0147

Alternate gene names: 71905789

Gene position: 161922-161356 (Counterclockwise)

Preceding gene: 71905792

Following gene: 71905788

Centisome position: 3.6

GC content: 67.2

Gene sequence:

>567_bases
ATGCCGCCCATGAAAGAACTGATTCTCGGCGGTGCCCGGTCGGGCAAGAGCCTGCTGGCCGAACAACGCGCCCACGACTC
CGGACTGAAGGTGACCTACCTCGCCACGGCCCAGGCGCTCGATGGCGAAATGGCCCGCCGCGTGGCCCATCATCGCGAAC
GCCGGCCGGTCGAGTGGGGCTGCATCGAAGAAACACTGCATCTGGCGGCCTGCCTGCGCGAGTTGGCAGCGGCGGATACC
TGCGTGCTGGTCGACTGCCTGACCCTGTGGCTGTCCAACCTGTTGTTCGCCGGCCAGGCCGCGGCACAGGCTGAAGCAGG
CGAAGCCATCGACTGCCCGCTGTTCCGCGCGGAAACCAGCGCGCTGATCGAACTGCTGCCGCAGCTGCCCGGCCGCATCA
TTCTGGTTTCCAATGAGGTCGGCTGGGGCATCGTGCCGATGCATCCGGTATCGCGCCTCTTCGCCGATGAACAGGGACGC
CTGAACCAGCGCGTCGCCGCCGTTTGCGACCAGGTCACGCTGGTCGCCGCCGGACTGCCACTCAGCCTCAAGTCCACCGC
GGGCTGA

Upstream 100 bases:

>100_bases
AGCGGCGGGCCCGCCCCGGAATTGAGTCAGACTCGCACCGGGTTCCGTATTGTCGAAGGCGAAATTATACCGGTTGCCGC
CGGGCCGGCCTTCACCCAAA

Downstream 100 bases:

>100_bases
TCGGACTGCCAATTCGGAATGCATTTCTCCGAAGGCAGGCATCTCGACAAAAAGATCGGTATCCTTGTTGCAGATAGACA
CGCAAGATGTCTTTGGAGGG

Product: adenosylcobinamide kinase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MPPMKELILGGARSGKSLLAEQRAHDSGLKVTYLATAQALDGEMARRVAHHRERRPVEWGCIEETLHLAACLRELAAADT
CVLVDCLTLWLSNLLFAGQAAAQAEAGEAIDCPLFRAETSALIELLPQLPGRIILVSNEVGWGIVPMHPVSRLFADEQGR
LNQRVAAVCDQVTLVAAGLPLSLKSTAG

Sequences:

>Translated_188_residues
MPPMKELILGGARSGKSLLAEQRAHDSGLKVTYLATAQALDGEMARRVAHHRERRPVEWGCIEETLHLAACLRELAAADT
CVLVDCLTLWLSNLLFAGQAAAQAEAGEAIDCPLFRAETSALIELLPQLPGRIILVSNEVGWGIVPMHPVSRLFADEQGR
LNQRVAAVCDQVTLVAAGLPLSLKSTAG
>Mature_187_residues
PPMKELILGGARSGKSLLAEQRAHDSGLKVTYLATAQALDGEMARRVAHHRERRPVEWGCIEETLHLAACLRELAAADTC
VLVDCLTLWLSNLLFAGQAAAQAEAGEAIDCPLFRAETSALIELLPQLPGRIILVSNEVGWGIVPMHPVSRLFADEQGRL
NQRVAAVCDQVTLVAAGLPLSLKSTAG

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=183, Percent_Identity=39.8907103825137, Blast_Score=122, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 20153; Mature: 20021

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPMKELILGGARSGKSLLAEQRAHDSGLKVTYLATAQALDGEMARRVAHHRERRPVEWG
CCCHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCH
CIEETLHLAACLRELAAADTCVLVDCLTLWLSNLLFAGQAAAQAEAGEAIDCPLFRAETS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCHHHHHHH
ALIELLPQLPGRIILVSNEVGWGIVPMHPVSRLFADEQGRLNQRVAAVCDQVTLVAAGLP
HHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
LSLKSTAG
CCCCCCCC
>Mature Secondary Structure 
PPMKELILGGARSGKSLLAEQRAHDSGLKVTYLATAQALDGEMARRVAHHRERRPVEWG
CCHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCH
CIEETLHLAACLRELAAADTCVLVDCLTLWLSNLLFAGQAAAQAEAGEAIDCPLFRAETS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCHHHHHHH
ALIELLPQLPGRIILVSNEVGWGIVPMHPVSRLFADEQGRLNQRVAAVCDQVTLVAAGLP
HHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
LSLKSTAG
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]