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The map label for this gene is mreB [H]

Identifier: 71905758

GI number: 71905758

Start: 132912

End: 133955

Strand: Reverse

Name: mreB [H]

Synonym: Daro_0116

Alternate gene names: 71905758

Gene position: 133955-132912 (Counterclockwise)

Preceding gene: 71905763

Following gene: 71905757

Centisome position: 2.98

GC content: 60.44

Gene sequence:

>1044_bases
ATGTTTGGTTTCCTCAGCAAATACTTCTCGAACGACCTCGCCATTGACCTTGGTACTGCCAACACGCTGATCTATGTGCG
TGCTCGCGGCATCGTTCTGGACGAGCCGTCGGTCGTCGCCATCCGCCTCGAAGGCGGCCCCAATGCCAAAAAGACCATCC
AGGCCGTCGGCCGGGAAGCCAAGGATATGCTTGGCAAGGCACCGGGTACCATCACTGTTATCCGCCCGATGAAGGACGGC
GTGATTGCCGACTTCACCGTCACCGAGCAAATGCTCAAGCAATTCATCAAAAAGGTGCACGACTCGAAGCTGTTCAGCCC
GAGCCCGCGCATCATCATCTGCGTTCCGTCCGGCTCGACCCAGGTCGAACGCCGCGCCATCCGCGAATCCGCCCTCGGCG
CCGGTGCCAGCCAGGTTTACCTGATTGAGGAGCCGATGGCGGCTGCGATCGGTGCCGGCCTGCCGGTTTCCGATGCAACG
GGCTCCATGGTCGTCGACATCGGCGGCGGCACCACCGAAGTTGGTGTCATCTCGCTCGGCGGCATGGTCTATGCCGGTTC
CGTGCGCGTCGGCGGCGACAAGCTGGACGAAGCGATCATCAATTACATCAGCCGCAACTACGGCATGATGATCGGCGAGA
ACACCGCCGAAAACATCAAGAAGAACATCGGTTCCGCCTTCCCGGGCGCCGAGGTCAAGGAAATGGAAGTTTCCGGCATC
AACAAGGCCGAAGGCATCCCGCGCAAGTTCACGATTTCGTCCAACGAAATCCTTGAGGCGCTGACCGACCCGCTGAACCA
GATCGTTTCCGCCGTGAAGTCCGCGCTGGAAAAGACTCCGCCCGAACTCGGTGCCGACATTGCCGAAAAGGGCATGGTAT
TGACTGGCGGCGGCGCCCTGCTCCGCGACCTCGACCGTCTGCTGATGGAAGAAACCGGCCTCCCTGTGATCGTTGCCGAT
GAGCCCCTGACCTGTGTTGCCCGCGGTTGCGGCATGGCACTGGAAAAGATGGACAAGCTGGGCAGCATTTTTGCCTCGGA
CTAA

Upstream 100 bases:

>100_bases
GGTGCCAAAGACTTTTTTGCAGTGCACAAAGTCTTAAAATGGAAAGCGTTATAAGGTATCATAAAAGTTTTCCCTACCGC
ACCCCCCAAGCGGAGCATAC

Downstream 100 bases:

>100_bases
ACCTTGATCGCAGCAAGGCAGGATTGAACGATGGCCGGCCTCGACCACGCGCCTCCACCGTTCTTCAAGCGAGGGCCAGC
ACCGCTGGCCCTTCTGACTT

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFGFLSKYFSNDLAIDLGTANTLIYVRARGIVLDEPSVVAIRLEGGPNAKKTIQAVGREAKDMLGKAPGTITVIRPMKDG
VIADFTVTEQMLKQFIKKVHDSKLFSPSPRIIICVPSGSTQVERRAIRESALGAGASQVYLIEEPMAAAIGAGLPVSDAT
GSMVVDIGGGTTEVGVISLGGMVYAGSVRVGGDKLDEAIINYISRNYGMMIGENTAENIKKNIGSAFPGAEVKEMEVSGI
NKAEGIPRKFTISSNEILEALTDPLNQIVSAVKSALEKTPPELGADIAEKGMVLTGGGALLRDLDRLLMEETGLPVIVAD
EPLTCVARGCGMALEKMDKLGSIFASD

Sequences:

>Translated_347_residues
MFGFLSKYFSNDLAIDLGTANTLIYVRARGIVLDEPSVVAIRLEGGPNAKKTIQAVGREAKDMLGKAPGTITVIRPMKDG
VIADFTVTEQMLKQFIKKVHDSKLFSPSPRIIICVPSGSTQVERRAIRESALGAGASQVYLIEEPMAAAIGAGLPVSDAT
GSMVVDIGGGTTEVGVISLGGMVYAGSVRVGGDKLDEAIINYISRNYGMMIGENTAENIKKNIGSAFPGAEVKEMEVSGI
NKAEGIPRKFTISSNEILEALTDPLNQIVSAVKSALEKTPPELGADIAEKGMVLTGGGALLRDLDRLLMEETGLPVIVAD
EPLTCVARGCGMALEKMDKLGSIFASD
>Mature_347_residues
MFGFLSKYFSNDLAIDLGTANTLIYVRARGIVLDEPSVVAIRLEGGPNAKKTIQAVGREAKDMLGKAPGTITVIRPMKDG
VIADFTVTEQMLKQFIKKVHDSKLFSPSPRIIICVPSGSTQVERRAIRESALGAGASQVYLIEEPMAAAIGAGLPVSDAT
GSMVVDIGGGTTEVGVISLGGMVYAGSVRVGGDKLDEAIINYISRNYGMMIGENTAENIKKNIGSAFPGAEVKEMEVSGI
NKAEGIPRKFTISSNEILEALTDPLNQIVSAVKSALEKTPPELGADIAEKGMVLTGGGALLRDLDRLLMEETGLPVIVAD
EPLTCVARGCGMALEKMDKLGSIFASD

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=341, Percent_Identity=70.6744868035191, Blast_Score=484, Evalue=1e-138,
Organism=Saccharomyces cerevisiae, GI6323401, Length=265, Percent_Identity=25.6603773584906, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322426, Length=233, Percent_Identity=24.4635193133047, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36547; Mature: 36547

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGFLSKYFSNDLAIDLGTANTLIYVRARGIVLDEPSVVAIRLEGGPNAKKTIQAVGREA
CCCHHHHHHCCCEEEEECCCCEEEEEEECCEEECCCCEEEEEECCCCCHHHHHHHHHHHH
KDMLGKAPGTITVIRPMKDGVIADFTVTEQMLKQFIKKVHDSKLFSPSPRIIICVPSGST
HHHHCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCH
QVERRAIRESALGAGASQVYLIEEPMAAAIGAGLPVSDATGSMVVDIGGGTTEVGVISLG
HHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GMVYAGSVRVGGDKLDEAIINYISRNYGMMIGENTAENIKKNIGSAFPGAEVKEMEVSGI
CEEEECEEEECCHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHCCCCCCCCCEEEECCCC
NKAEGIPRKFTISSNEILEALTDPLNQIVSAVKSALEKTPPELGADIAEKGMVLTGGGAL
CHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHCCEEEECCCHH
LRDLDRLLMEETGLPVIVADEPLTCVARGCGMALEKMDKLGSIFASD
HHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFGFLSKYFSNDLAIDLGTANTLIYVRARGIVLDEPSVVAIRLEGGPNAKKTIQAVGREA
CCCHHHHHHCCCEEEEECCCCEEEEEEECCEEECCCCEEEEEECCCCCHHHHHHHHHHHH
KDMLGKAPGTITVIRPMKDGVIADFTVTEQMLKQFIKKVHDSKLFSPSPRIIICVPSGST
HHHHCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCH
QVERRAIRESALGAGASQVYLIEEPMAAAIGAGLPVSDATGSMVVDIGGGTTEVGVISLG
HHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GMVYAGSVRVGGDKLDEAIINYISRNYGMMIGENTAENIKKNIGSAFPGAEVKEMEVSGI
CEEEECEEEECCHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHCCCCCCCCCEEEECCCC
NKAEGIPRKFTISSNEILEALTDPLNQIVSAVKSALEKTPPELGADIAEKGMVLTGGGAL
CHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHCCEEEECCCHH
LRDLDRLLMEETGLPVIVADEPLTCVARGCGMALEKMDKLGSIFASD
HHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]