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The map label for this gene is mrdB [H]

Identifier: 71905754

GI number: 71905754

Start: 128387

End: 129499

Strand: Reverse

Name: mrdB [H]

Synonym: Daro_0112

Alternate gene names: 71905754

Gene position: 129499-128387 (Counterclockwise)

Preceding gene: 71905755

Following gene: 71905753

Centisome position: 2.88

GC content: 58.76

Gene sequence:

>1113_bases
ATGATCGACATCGTTGGCACCCTCCGCCGCAGTTGGCAGCAGTTGATCGCCCACATCGATTTTCCGCTGCTCTTCATCAC
GCTGACCATCATGGCGGTCGGCCTCGCCACCGTCTATTCCGCGACCTTCGACGGCAACCAGCGAGTGCTCTCCCAGTTGG
GCAACATGGGCGTGGCCATGACCATCATGTGGTTCGTTTCCCGACTACCGCCCCAGAAACTGATGCGCTTTGCCATTCCG
CTCTACGTCCTGGGCGTTGTGCTGCTTGTCGCCGTCTTCCTGTTCGGGATCAAGGTCAATGGCGCCAAGCGCTGGCTACC
ACTTGGCTTCACACGCATCCAGCCATCCGAGATCATGAAGATCGCCATGCCGCTGATGCTGGCCTGGTATTTCCAGAAAT
ATGAAGCAACCCTCAGGTTCAAGCACTACATTGGCGCAGGTCTTTTGCTGCTCATCCCTTTTGCCCTGATCGCCAAGCAA
CCCGACCTCGGCACGGCCTTACTCGTCGGTGCTGCCGGCTTCTACGTGATCTTCTTTGCCGGCCTGCCATGGAAGGTCAT
CGCCGGCCTGGTCATCGCCGCCGGGTCTGCCGCTCCCCTGATCTGGAGCATGATGCACGACTATCAACGTAAACGCATCC
TGACCCTACTCGACCCGACCACCGACCCACTGGGTGCTGGCTATCACATCATCCAGGCCACCATCGCCATCGGTTCGGGC
GGCGCCATTGGCAAAGGCTACTTGAATGGTACGCAGACGCATCTCGAATTCATCCCGGAAAAGCATACCGACTTCATCTT
CGCCGTCTATTCCGAGGAATGGGGGCTGATCGGCAACGCGACGCTGGTTTTCCTCTACACCCTGCTCATCGGCCGCGGCC
TGATCATCGCCTCGGCGGCCCCGACGCTATTCACACGCCTTCTGGCCGGCGCCATCACCCTTGGCTTCTTTACCTACGCC
TTTATCAACATGGGCATGGTCAGCGGCATCCTGCCCGTCGTCGGTGTCCCGCTGCCCTTCATGAGCTACGGTGGCACGGC
TTTGGTTACACTCTTCCTTGGCATTGGGATTCTGATGTCGATCCATACCCACCGGATGCTGGTCAAGAAATGA

Upstream 100 bases:

>100_bases
CGCCTATCGCCCGCATGGTCATTGACTACTATCTGCTCGGCAAGTTGCCGGGCGGTGCCGCCAAAGATGACCCAGCCGCC
ATCGAAGAGGATAGCGAGGA

Downstream 100 bases:

>100_bases
GTCGTTTTGTCGCCCCGTTGAGTCTTGCGCTGCTGCTTGCCGCCTGTGGCGGCCCCAGTCCGATTCGCGACACAACGGTT
GACGGGCAAAAAGGATCTGT

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MIDIVGTLRRSWQQLIAHIDFPLLFITLTIMAVGLATVYSATFDGNQRVLSQLGNMGVAMTIMWFVSRLPPQKLMRFAIP
LYVLGVVLLVAVFLFGIKVNGAKRWLPLGFTRIQPSEIMKIAMPLMLAWYFQKYEATLRFKHYIGAGLLLLIPFALIAKQ
PDLGTALLVGAAGFYVIFFAGLPWKVIAGLVIAAGSAAPLIWSMMHDYQRKRILTLLDPTTDPLGAGYHIIQATIAIGSG
GAIGKGYLNGTQTHLEFIPEKHTDFIFAVYSEEWGLIGNATLVFLYTLLIGRGLIIASAAPTLFTRLLAGAITLGFFTYA
FINMGMVSGILPVVGVPLPFMSYGGTALVTLFLGIGILMSIHTHRMLVKK

Sequences:

>Translated_370_residues
MIDIVGTLRRSWQQLIAHIDFPLLFITLTIMAVGLATVYSATFDGNQRVLSQLGNMGVAMTIMWFVSRLPPQKLMRFAIP
LYVLGVVLLVAVFLFGIKVNGAKRWLPLGFTRIQPSEIMKIAMPLMLAWYFQKYEATLRFKHYIGAGLLLLIPFALIAKQ
PDLGTALLVGAAGFYVIFFAGLPWKVIAGLVIAAGSAAPLIWSMMHDYQRKRILTLLDPTTDPLGAGYHIIQATIAIGSG
GAIGKGYLNGTQTHLEFIPEKHTDFIFAVYSEEWGLIGNATLVFLYTLLIGRGLIIASAAPTLFTRLLAGAITLGFFTYA
FINMGMVSGILPVVGVPLPFMSYGGTALVTLFLGIGILMSIHTHRMLVKK
>Mature_370_residues
MIDIVGTLRRSWQQLIAHIDFPLLFITLTIMAVGLATVYSATFDGNQRVLSQLGNMGVAMTIMWFVSRLPPQKLMRFAIP
LYVLGVVLLVAVFLFGIKVNGAKRWLPLGFTRIQPSEIMKIAMPLMLAWYFQKYEATLRFKHYIGAGLLLLIPFALIAKQ
PDLGTALLVGAAGFYVIFFAGLPWKVIAGLVIAAGSAAPLIWSMMHDYQRKRILTLLDPTTDPLGAGYHIIQATIAIGSG
GAIGKGYLNGTQTHLEFIPEKHTDFIFAVYSEEWGLIGNATLVFLYTLLIGRGLIIASAAPTLFTRLLAGAITLGFFTYA
FINMGMVSGILPVVGVPLPFMSYGGTALVTLFLGIGILMSIHTHRMLVKK

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=360, Percent_Identity=48.8888888888889, Blast_Score=312, Evalue=3e-86,
Organism=Escherichia coli, GI1786277, Length=380, Percent_Identity=30.2631578947368, Blast_Score=160, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40469; Mature: 40469

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDIVGTLRRSWQQLIAHIDFPLLFITLTIMAVGLATVYSATFDGNQRVLSQLGNMGVAM
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHH
TIMWFVSRLPPQKLMRFAIPLYVLGVVLLVAVFLFGIKVNGAKRWLPLGFTRIQPSEIMK
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCEEEECCCCCCCHHHHHH
IAMPLMLAWYFQKYEATLRFKHYIGAGLLLLIPFALIAKQPDLGTALLVGAAGFYVIFFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
GLPWKVIAGLVIAAGSAAPLIWSMMHDYQRKRILTLLDPTTDPLGAGYHIIQATIAIGSG
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHEEEEECCC
GAIGKGYLNGTQTHLEFIPEKHTDFIFAVYSEEWGLIGNATLVFLYTLLIGRGLIIASAA
CCCCCCCCCCCHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEECCH
PTLFTRLLAGAITLGFFTYAFINMGMVSGILPVVGVPLPFMSYGGTALVTLFLGIGILMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHH
IHTHRMLVKK
HHHHHHHHCC
>Mature Secondary Structure
MIDIVGTLRRSWQQLIAHIDFPLLFITLTIMAVGLATVYSATFDGNQRVLSQLGNMGVAM
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHH
TIMWFVSRLPPQKLMRFAIPLYVLGVVLLVAVFLFGIKVNGAKRWLPLGFTRIQPSEIMK
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCEEEECCCCCCCHHHHHH
IAMPLMLAWYFQKYEATLRFKHYIGAGLLLLIPFALIAKQPDLGTALLVGAAGFYVIFFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
GLPWKVIAGLVIAAGSAAPLIWSMMHDYQRKRILTLLDPTTDPLGAGYHIIQATIAIGSG
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHEEEEECCC
GAIGKGYLNGTQTHLEFIPEKHTDFIFAVYSEEWGLIGNATLVFLYTLLIGRGLIIASAA
CCCCCCCCCCCHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEECCH
PTLFTRLLAGAITLGFFTYAFINMGMVSGILPVVGVPLPFMSYGGTALVTLFLGIGILMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHH
IHTHRMLVKK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]