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The map label for this gene is fabG [H]

Identifier: 71905729

GI number: 71905729

Start: 103668

End: 104351

Strand: Reverse

Name: fabG [H]

Synonym: Daro_0087

Alternate gene names: 71905729

Gene position: 104351-103668 (Counterclockwise)

Preceding gene: 71905730

Following gene: 71905728

Centisome position: 2.32

GC content: 62.28

Gene sequence:

>684_bases
ATGTCCAACCAAAGCCTAGTCGGCAAGCGAGTGCTCATTACCCAGGCCGATATGTTCATGGGGCCAGTGCTCTGCGAGGT
ATTTGCCCGGCATGGCGCAACGGTCATTGCCAATACGGATGCTCTGCTTGCGCCTGATGCCCCGGCCACCGTGGTCGCAC
AAGCAGGTCAGATTGATGCGCTGGTCGCCAATCTGGCCATGCCGGCACCGACGACAGCAGCCACGGAAGTCTCGGATGAG
GAATGGCGTGACACCTTCGCCATCCTCGTCGATCCGCTGGCCCGATTGCTCCGTGCGGCCCTGCCAGCCATGATAGAGCG
GCGGTCTGGCAAGATTCTGGTGATGGGCAGCGCGTCGGCCCTGCGCGGGATGAAGCGTGCGTCCACCTACAGCGCTGCAC
GCGGCGCCCAGCTGGCCTACGTTCAGGCGGTCGGTGTGGAAGTCGCGCCGCACAACGTTCAGGTCAATGCCATTGCGCAG
AATTTCGTCGATAACCCGACTTATTTCCCGCCCGAAGTTCAGGCCAACCCGCGCTTCCAGGAGCGCCTGAAGCGTGAGGT
TCCGCTCGGGCGTCTGGTCGGCGCCGATGAAGATGCCGAGTTTGCGGCTTATCTGTGCAGCGATTCGGCGAATTGTTTTG
TCGGGCAGGTCTTTCCGGTTTGCGGCGGCTGGGTGATGCGCTAG

Upstream 100 bases:

>100_bases
CCATCACCTTCGGGACACAGCTGCCGCAGATGGGCAACCGAAACCATCGGGGGCAGCCAAGCATTTACCACTTGATCCAC
TTGTCGTTACAGGAGCCGCG

Downstream 100 bases:

>100_bases
CGAAGCCTGATCCCGCTGCTTTAAAACGAATAGCGCCTGCTTTTGTTTAACCAAACCTCTCAAAATCCACTGCCGAGCAT
TCGCCATGTCCCTCCCCGCC

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSNQSLVGKRVLITQADMFMGPVLCEVFARHGATVIANTDALLAPDAPATVVAQAGQIDALVANLAMPAPTTAATEVSDE
EWRDTFAILVDPLARLLRAALPAMIERRSGKILVMGSASALRGMKRASTYSAARGAQLAYVQAVGVEVAPHNVQVNAIAQ
NFVDNPTYFPPEVQANPRFQERLKREVPLGRLVGADEDAEFAAYLCSDSANCFVGQVFPVCGGWVMR

Sequences:

>Translated_227_residues
MSNQSLVGKRVLITQADMFMGPVLCEVFARHGATVIANTDALLAPDAPATVVAQAGQIDALVANLAMPAPTTAATEVSDE
EWRDTFAILVDPLARLLRAALPAMIERRSGKILVMGSASALRGMKRASTYSAARGAQLAYVQAVGVEVAPHNVQVNAIAQ
NFVDNPTYFPPEVQANPRFQERLKREVPLGRLVGADEDAEFAAYLCSDSANCFVGQVFPVCGGWVMR
>Mature_226_residues
SNQSLVGKRVLITQADMFMGPVLCEVFARHGATVIANTDALLAPDAPATVVAQAGQIDALVANLAMPAPTTAATEVSDEE
WRDTFAILVDPLARLLRAALPAMIERRSGKILVMGSASALRGMKRASTYSAARGAQLAYVQAVGVEVAPHNVQVNAIAQN
FVDNPTYFPPEVQANPRFQERLKREVPLGRLVGADEDAEFAAYLCSDSANCFVGQVFPVCGGWVMR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=175, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI66933014, Length=244, Percent_Identity=26.2295081967213, Blast_Score=67, Evalue=9e-12,
Organism=Homo sapiens, GI126723750, Length=148, Percent_Identity=25.6756756756757, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=29.0983606557377, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=26.6932270916335, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=26.7716535433071, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788459, Length=178, Percent_Identity=28.0898876404494, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI87082160, Length=210, Percent_Identity=24.2857142857143, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1789208, Length=177, Percent_Identity=25.9887005649718, Blast_Score=62, Evalue=4e-11,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=26.2948207171315, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355319, Length=176, Percent_Identity=23.2954545454545, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24244; Mature: 24113

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQSLVGKRVLITQADMFMGPVLCEVFARHGATVIANTDALLAPDAPATVVAQAGQIDA
CCCCHHCCCEEEEEHHHHHHHHHHHHHHHHCCCEEEECCCEEECCCCCHHHHCCCCCHHH
LVANLAMPAPTTAATEVSDEEWRDTFAILVDPLARLLRAALPAMIERRSGKILVMGSASA
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHH
LRGMKRASTYSAARGAQLAYVQAVGVEVAPHNVQVNAIAQNFVDNPTYFPPEVQANPRFQ
HHHHHHHHHHHHHCCCEEEEEEEECEEECCCCEEEHHHHHHHCCCCCCCCCCCCCCCCHH
ERLKREVPLGRLVGADEDAEFAAYLCSDSANCFVGQVFPVCGGWVMR
HHHHHHCCHHHHCCCCCCHHHHHHHHCCCCCEEEEEHHHHCCCCCCC
>Mature Secondary Structure 
SNQSLVGKRVLITQADMFMGPVLCEVFARHGATVIANTDALLAPDAPATVVAQAGQIDA
CCCHHCCCEEEEEHHHHHHHHHHHHHHHHCCCEEEECCCEEECCCCCHHHHCCCCCHHH
LVANLAMPAPTTAATEVSDEEWRDTFAILVDPLARLLRAALPAMIERRSGKILVMGSASA
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHH
LRGMKRASTYSAARGAQLAYVQAVGVEVAPHNVQVNAIAQNFVDNPTYFPPEVQANPRFQ
HHHHHHHHHHHHHCCCEEEEEEEECEEECCCCEEEHHHHHHHCCCCCCCCCCCCCCCCHH
ERLKREVPLGRLVGADEDAEFAAYLCSDSANCFVGQVFPVCGGWVMR
HHHHHHCCHHHHCCCCCCHHHHHHHHCCCCCEEEEEHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1556094; 8905232; 9278503; 1314802 [H]