Click here to switch to the map view.

The map label for this gene is mraW

Identifier: 71891921

GI number: 71891921

Start: 169378

End: 170367

Strand: Direct

Name: mraW

Synonym: BPEN_138

Alternate gene names: 71891921

Gene position: 169378-170367 (Clockwise)

Preceding gene: 71891911

Following gene: 71891922

Centisome position: 21.4

GC content: 30.91

Gene sequence:

>990_bases
ATGTGTGCATCTGTATTTTTTATTATTATATACATGTTCTATATTCACTACAGTCATAAAAGTGTATTGCTAAATGAAGC
GATACAATCATTGAATATTAAAGCAACAGGAATGTATATTGACGGAACGTTTGGTTCAGGAGGTCATTCTAAATTAATTT
TATCTCAATTAAATAAACGAGGTCGTTTGTTAGCAATAGATAAAGATTTATTGGCTGTCAAAATTGGAAAGCACATTGCT
GAACAAGATGATAGATTTACTATAATACATAGTTCATTTTCCAAAATGATCAACCATGTTAAAAATATAGGATTAATTGG
ATCAGTGGATGGTATTTTACTAGATTTAGGGATCAGTACATTTCAGATAAATGATTGTAGCAGAGGATTTTCGTTTATGC
AAGATGGTCTACTAGATATGCGGATGGACATTAGTAGCGGAATATCTGCTGCTGAATGGTTATCGAAGGCATCTCAAGAA
AATATTACTTGGGTTTTAAAAAATTTTGGAGAAGAACGATTTGCAAAAAATATCGCTAAGATTTTAGTGTCTAAAAGACG
ATACACGCCTATTATACGCTCGATTGTTTTATCGAAATTAATCTGCGATGCTATTCCGCATCGCAATATGAATAAACATC
CTGCAACTAAAAGTTTTCTGGCAATTAGAATGTTCATTAATAATGAACTAGAAGAAATAATGCAAGTATTAAAAGATGCA
TTGATTATATTGTCTCCACGAGGCAGATTGGTGGTAATTAGTTTTAATTCTCTAGAAGATCGATTGGTAAAATACTTCAT
TCGTGAACATAGTTGTGCTTTATCTATTCCTCCCAAGCTTCCATTAACAAATAATCAAATATTTAGTAAATATAAAAATA
AGTGTCAATTAAAAAATATAGGAAAATTAACACCTTCAAAACAAGAAATTAAAAGAAATATACGTGCTCGTAGCGCGATA
TTACGTTGCGCTGAAAAATTGGCTATCTAA

Upstream 100 bases:

>100_bases
ATTTCAATTGCAGTTCATATAAACACTTAGTAGTATGAAACATAGAAAGTTGCGTGTCTGATATTTTTTATTATTAAGTA
TTTTGTTCATAAAATAACAA

Downstream 100 bases:

>100_bases
ATATGACGGAAAAGAAACAATATAACCTTGTTAGTATTATTTATGATGATTTGTGCTTATATGGTAAGTGGCAGTTGCTT
TTATTGTTGTTAGTGTTAAT

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MCASVFFIIIYMFYIHYSHKSVLLNEAIQSLNIKATGMYIDGTFGSGGHSKLILSQLNKRGRLLAIDKDLLAVKIGKHIA
EQDDRFTIIHSSFSKMINHVKNIGLIGSVDGILLDLGISTFQINDCSRGFSFMQDGLLDMRMDISSGISAAEWLSKASQE
NITWVLKNFGEERFAKNIAKILVSKRRYTPIIRSIVLSKLICDAIPHRNMNKHPATKSFLAIRMFINNELEEIMQVLKDA
LIILSPRGRLVVISFNSLEDRLVKYFIREHSCALSIPPKLPLTNNQIFSKYKNKCQLKNIGKLTPSKQEIKRNIRARSAI
LRCAEKLAI

Sequences:

>Translated_329_residues
MCASVFFIIIYMFYIHYSHKSVLLNEAIQSLNIKATGMYIDGTFGSGGHSKLILSQLNKRGRLLAIDKDLLAVKIGKHIA
EQDDRFTIIHSSFSKMINHVKNIGLIGSVDGILLDLGISTFQINDCSRGFSFMQDGLLDMRMDISSGISAAEWLSKASQE
NITWVLKNFGEERFAKNIAKILVSKRRYTPIIRSIVLSKLICDAIPHRNMNKHPATKSFLAIRMFINNELEEIMQVLKDA
LIILSPRGRLVVISFNSLEDRLVKYFIREHSCALSIPPKLPLTNNQIFSKYKNKCQLKNIGKLTPSKQEIKRNIRARSAI
LRCAEKLAI
>Mature_329_residues
MCASVFFIIIYMFYIHYSHKSVLLNEAIQSLNIKATGMYIDGTFGSGGHSKLILSQLNKRGRLLAIDKDLLAVKIGKHIA
EQDDRFTIIHSSFSKMINHVKNIGLIGSVDGILLDLGISTFQINDCSRGFSFMQDGLLDMRMDISSGISAAEWLSKASQE
NITWVLKNFGEERFAKNIAKILVSKRRYTPIIRSIVLSKLICDAIPHRNMNKHPATKSFLAIRMFINNELEEIMQVLKDA
LIILSPRGRLVVISFNSLEDRLVKYFIREHSCALSIPPKLPLTNNQIFSKYKNKCQLKNIGKLTPSKQEIKRNIRARSAI
LRCAEKLAI

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=338, Percent_Identity=34.9112426035503, Blast_Score=177, Evalue=9e-45,
Organism=Homo sapiens, GI165377202, Length=190, Percent_Identity=33.6842105263158, Blast_Score=112, Evalue=6e-25,
Organism=Escherichia coli, GI1786270, Length=311, Percent_Identity=52.7331189710611, Blast_Score=348, Evalue=3e-97,
Organism=Drosophila melanogaster, GI62472493, Length=333, Percent_Identity=35.4354354354354, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28571637, Length=333, Percent_Identity=35.4354354354354, Blast_Score=162, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_BLOPB (Q493Q9)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277651.1
- ProteinModelPortal:   Q493Q9
- SMR:   Q493Q9
- STRING:   Q493Q9
- GeneID:   3563106
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_138
- eggNOG:   COG0275
- HOGENOM:   HBG302779
- OMA:   PQLDDPE
- ProtClustDB:   PRK00050
- BioCyc:   CBLO291272:BPEN_138-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 37256; Mature: 37256

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: BINDING 67-67 BINDING 93-93 BINDING 115-115 BINDING 122-122

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCASVFFIIIYMFYIHYSHKSVLLNEAIQSLNIKATGMYIDGTFGSGGHSKLILSQLNKR
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHCCC
GRLLAIDKDLLAVKIGKHIAEQDDRFTIIHSSFSKMINHVKNIGLIGSVDGILLDLGIST
CCEEEECCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCEECCCHHHEECCCCE
FQINDCSRGFSFMQDGLLDMRMDISSGISAAEWLSKASQENITWVLKNFGEERFAKNIAK
EEECCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHH
ILVSKRRYTPIIRSIVLSKLICDAIPHRNMNKHPATKSFLAIRMFINNELEEIMQVLKDA
HHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LIILSPRGRLVVISFNSLEDRLVKYFIREHSCALSIPPKLPLTNNQIFSKYKNKCQLKNI
HEEECCCCCEEEEECCCHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHCCCCCC
GKLTPSKQEIKRNIRARSAILRCAEKLAI
CCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MCASVFFIIIYMFYIHYSHKSVLLNEAIQSLNIKATGMYIDGTFGSGGHSKLILSQLNKR
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHCCC
GRLLAIDKDLLAVKIGKHIAEQDDRFTIIHSSFSKMINHVKNIGLIGSVDGILLDLGIST
CCEEEECCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCEECCCHHHEECCCCE
FQINDCSRGFSFMQDGLLDMRMDISSGISAAEWLSKASQENITWVLKNFGEERFAKNIAK
EEECCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHH
ILVSKRRYTPIIRSIVLSKLICDAIPHRNMNKHPATKSFLAIRMFINNELEEIMQVLKDA
HHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LIILSPRGRLVVISFNSLEDRLVKYFIREHSCALSIPPKLPLTNNQIFSKYKNKCQLKNI
HEEECCCCCEEEEECCCHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHCCCCCC
GKLTPSKQEIKRNIRARSAILRCAEKLAI
CCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA