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The map label for this gene is carA [H]

Identifier: 71891909

GI number: 71891909

Start: 151822

End: 152961

Strand: Direct

Name: carA [H]

Synonym: BPEN_126

Alternate gene names: 71891909

Gene position: 151822-152961 (Clockwise)

Preceding gene: 71891908

Following gene: 71891910

Centisome position: 19.18

GC content: 34.12

Gene sequence:

>1140_bases
ATGAAATCAGCATTGTTAGTACTAGAAGATGGTAATCAATTTTATGGTTATGCAATAGGCGCAGAAGGAGAAACAGTAGG
AGAAGTAGTGTTTAACACATCAATGACTGGATATCAAGAAATAATTACTGACCCTTCTTATGCTTATCAAATAGTCATAT
TAACTTGTCCTCATATTGGAAATGTGGGTACTAATGAATTTGATAATGAATCTTCTTGTATTCAGGTAAGAGGACTAATT
ATTCGTGACCTAGCAATGGTTGTTAGTAATTTTCGTTATACATTGAGCCTTTCAGATTATTTAGTGCAACAAAATATTGT
TGGAATTGCTGGAGTAGATACTCGTAAGTTAACTCGTTTAATACGAGAAAAAGGAATACAACACGGCTGTATCATTGCTT
GTGATATGCCTGATGCTACATTAGCATTGCGTAAGGCTCGTGAATTTACTGGATTGAGTGGACTTAATCTTGTTCATGAA
GTAAGTACTTCTCAACGGTATATTTGGAATCAAGGTACTTGGAATATTAAATCTGGAGTATTCTGCACTCCATTGTACTT
ACCTTATCGTGTTGTAGTATATGATTTTGGTGTTAAACGAAATATAATGCGTATATTAGTAGATTATGGTTGTTTATTAA
CTGTGGTTCCGGCACATACTACAGCGCAAGAAATAATTGATATGCAACCAGATGGTATCTTTCTGGCCAATGGGCCCGGA
GATCCAAATGCATATGAATACGCCATTAATTCTATACAAACTTTTTTAAATACAACTACAATCCCATTGTTTGGAATTTG
TTTAGGACATCAGTTACTTGCGTTAGCTAGCGGAGCTAAAACGGTAAAAATGAAATTTGGACATCATGGTTCCAATCATC
CAGTTAAAGATATAGAAACAAACAAGGTTATAATTACCGCGCAAAATCATAATTTTGTAGTAGACAAACAAACTTTACCT
GATACGTTGAAAATAACGCATATTTCATTATTTGATGGTACTCTCCAAGGTATTCATCATACTAATAAACCTGCTTTTAG
TTTTCAAGGACATCCAGAGGCTAGTCCTGGCCCTCATGATGCTGCATCATCGTTATTTGGTCATTTCATTAAATTAATTA
AAAATTACCGTAATAAATAA

Upstream 100 bases:

>100_bases
TATTATTAATTTAATATTTGACTTATCAATTTCTTCTAATAAATTAAATGTAAGTTATATACTTAATGATTTATTTATCT
ATTAAGATAGAGTTATTTTA

Downstream 100 bases:

>100_bases
TAAGTTTGAGAGTATAATAATATGCCAAAAAGAACCGATATACACAGCATCTTACTATTGGGAGCTGGACCAATAGTTAT
TGGTCAAGCCTGTGAATTTG

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKSALLVLEDGNQFYGYAIGAEGETVGEVVFNTSMTGYQEIITDPSYAYQIVILTCPHIGNVGTNEFDNESSCIQVRGLI
IRDLAMVVSNFRYTLSLSDYLVQQNIVGIAGVDTRKLTRLIREKGIQHGCIIACDMPDATLALRKAREFTGLSGLNLVHE
VSTSQRYIWNQGTWNIKSGVFCTPLYLPYRVVVYDFGVKRNIMRILVDYGCLLTVVPAHTTAQEIIDMQPDGIFLANGPG
DPNAYEYAINSIQTFLNTTTIPLFGICLGHQLLALASGAKTVKMKFGHHGSNHPVKDIETNKVIITAQNHNFVVDKQTLP
DTLKITHISLFDGTLQGIHHTNKPAFSFQGHPEASPGPHDAASSLFGHFIKLIKNYRNK

Sequences:

>Translated_379_residues
MKSALLVLEDGNQFYGYAIGAEGETVGEVVFNTSMTGYQEIITDPSYAYQIVILTCPHIGNVGTNEFDNESSCIQVRGLI
IRDLAMVVSNFRYTLSLSDYLVQQNIVGIAGVDTRKLTRLIREKGIQHGCIIACDMPDATLALRKAREFTGLSGLNLVHE
VSTSQRYIWNQGTWNIKSGVFCTPLYLPYRVVVYDFGVKRNIMRILVDYGCLLTVVPAHTTAQEIIDMQPDGIFLANGPG
DPNAYEYAINSIQTFLNTTTIPLFGICLGHQLLALASGAKTVKMKFGHHGSNHPVKDIETNKVIITAQNHNFVVDKQTLP
DTLKITHISLFDGTLQGIHHTNKPAFSFQGHPEASPGPHDAASSLFGHFIKLIKNYRNK
>Mature_379_residues
MKSALLVLEDGNQFYGYAIGAEGETVGEVVFNTSMTGYQEIITDPSYAYQIVILTCPHIGNVGTNEFDNESSCIQVRGLI
IRDLAMVVSNFRYTLSLSDYLVQQNIVGIAGVDTRKLTRLIREKGIQHGCIIACDMPDATLALRKAREFTGLSGLNLVHE
VSTSQRYIWNQGTWNIKSGVFCTPLYLPYRVVVYDFGVKRNIMRILVDYGCLLTVVPAHTTAQEIIDMQPDGIFLANGPG
DPNAYEYAINSIQTFLNTTTIPLFGICLGHQLLALASGAKTVKMKFGHHGSNHPVKDIETNKVIITAQNHNFVVDKQTLP
DTLKITHISLFDGTLQGIHHTNKPAFSFQGHPEASPGPHDAASSLFGHFIKLIKNYRNK

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=383, Percent_Identity=38.1201044386423, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI21361331, Length=385, Percent_Identity=37.4025974025974, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI169790915, Length=385, Percent_Identity=37.4025974025974, Blast_Score=228, Evalue=5e-60,
Organism=Escherichia coli, GI1786215, Length=380, Percent_Identity=68.1578947368421, Blast_Score=539, Evalue=1e-154,
Organism=Caenorhabditis elegans, GI193204318, Length=388, Percent_Identity=34.5360824742268, Blast_Score=203, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6324878, Length=388, Percent_Identity=37.8865979381443, Blast_Score=229, Evalue=7e-61,
Organism=Saccharomyces cerevisiae, GI6322331, Length=392, Percent_Identity=35.2040816326531, Blast_Score=217, Evalue=2e-57,
Organism=Drosophila melanogaster, GI45555749, Length=388, Percent_Identity=35.5670103092784, Blast_Score=218, Evalue=6e-57,
Organism=Drosophila melanogaster, GI24642586, Length=388, Percent_Identity=35.5670103092784, Blast_Score=218, Evalue=6e-57,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 41875; Mature: 41875

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSALLVLEDGNQFYGYAIGAEGETVGEVVFNTSMTGYQEIITDPSYAYQIVILTCPHIG
CCCEEEEEECCCEEEEEEECCCCCEEEHEEEECCCCCHHHHHCCCCCEEEEEEEECCCCC
NVGTNEFDNESSCIQVRGLIIRDLAMVVSNFRYTLSLSDYLVQQNIVGIAGVDTRKLTRL
CCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCEEEECCCHHHHHHH
IREKGIQHGCIIACDMPDATLALRKAREFTGLSGLNLVHEVSTSQRYIWNQGTWNIKSGV
HHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCEEECCCE
FCTPLYLPYRVVVYDFGVKRNIMRILVDYGCLLTVVPAHTTAQEIIDMQPDGIFLANGPG
EEEECCCCEEEEEEECCCHHHHHHHHHHCCCEEEEECCCCCHHHHHCCCCCCEEEECCCC
DPNAYEYAINSIQTFLNTTTIPLFGICLGHQLLALASGAKTVKMKFGHHGSNHPVKDIET
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
NKVIITAQNHNFVVDKQTLPDTLKITHISLFDGTLQGIHHTNKPAFSFQGHPEASPGPHD
CEEEEEECCCCEEEECCCCCCEEEEEEEEEECCHHHHCCCCCCCCEEECCCCCCCCCCCH
AASSLFGHFIKLIKNYRNK
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSALLVLEDGNQFYGYAIGAEGETVGEVVFNTSMTGYQEIITDPSYAYQIVILTCPHIG
CCCEEEEEECCCEEEEEEECCCCCEEEHEEEECCCCCHHHHHCCCCCEEEEEEEECCCCC
NVGTNEFDNESSCIQVRGLIIRDLAMVVSNFRYTLSLSDYLVQQNIVGIAGVDTRKLTRL
CCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCEEEECCCHHHHHHH
IREKGIQHGCIIACDMPDATLALRKAREFTGLSGLNLVHEVSTSQRYIWNQGTWNIKSGV
HHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCEEECCCE
FCTPLYLPYRVVVYDFGVKRNIMRILVDYGCLLTVVPAHTTAQEIIDMQPDGIFLANGPG
EEEECCCCEEEEEEECCCHHHHHHHHHHCCCEEEEECCCCCHHHHHCCCCCCEEEECCCC
DPNAYEYAINSIQTFLNTTTIPLFGICLGHQLLALASGAKTVKMKFGHHGSNHPVKDIET
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
NKVIITAQNHNFVVDKQTLPDTLKITHISLFDGTLQGIHHTNKPAFSFQGHPEASPGPHD
CEEEEEECCCCEEEECCCCCCEEEEEEEEEECCHHHHCCCCCCCCEEECCCCCCCCCCCH
AASSLFGHFIKLIKNYRNK
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]