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The map label for this gene is tyrA

Identifier: 68537120

GI number: 68537120

Start: 2365577

End: 2366716

Strand: Direct

Name: tyrA

Synonym: jk2025

Alternate gene names: NA

Gene position: 2365577-2366716 (Clockwise)

Preceding gene: 68537115

Following gene: 68537124

Centisome position: 96.06

GC content: 69.74

Gene sequence:

>1140_bases
GTGAGCTACGAAATCTCTTCCGACTACCGCCTGAGCACCCTCCCCGAGGATCGCCGCCCGCTGTGCATCCTGGGGCTGGG
GCTGATCGGCGGCTCGCTGATGCGCGATGCGCAGGCCGCCGGCTGGCCCGTGTTCGGCTGGAATCGGTCGGAGAAAACCG
TCACCCGCGCGCGCCGCGATGGCTACGACGTCTCGGCCGACCTCGAGGCAACGCTCCGCCGCGCCGAGGAGACCGATGCA
CTGTTAATCCTCGGCGTACCGATGCCCGCGCTGTCTTTTCTTCTTGACGCCATATCTCAGCACGCCCCGACCTGCGGCTT
TACTGACGTGACCAGTGTGAAGCAGGAGGTGCACGACCTCGTGGAGGCGAAGGGCATGTCCGATCGCTTCGTGGGCGGGC
ATCCAATGGCTGGCACCGCAAACTCGGGCTGGCAGGCGACGATGCACGGGCTGTTCCGGGGTGCCGTGTGGGTCGTGACG
TATGACAACGCGCGGGAGCTTGCGGGGGCTGGCGCAGAGGCGGGCGCGGCCGCAAGCACGGGTTCCAGCGCGGCAGGCGG
CGGCGCGACTTCGGGCGCAGCGGGCGCGGCTCCCGGCGCCGACGCCGACGAGGTCAGCAAGCGCTGGCTGGATACGTGGG
TGCGCGTGGTCGGGCTGGCCGAGGAAGTCGGTGCGTCGGTAATCCCCGCCATCGCGCGCCGGCATGACAGCGCCGTGGGG
CGTGTCAGCCACCTGCCACACATCCTCGCCGAGTCGCTGGCAGTCGCCGGCGATAGTGGAGGTCCGCTGGCGCTGAGCCT
GGCGGCGTCCAGCTTCCGCGACGGCACGCGCGTGGCTGGCACGGATCCGGACCTGGTGCGCGCGATGGTGGAGAACAACC
GTCCTGCCGTGCTAGAGGCCTTGGACCAGACCATCGAACTGCTGCAGGGCGCGCGGGAGGATATCGCCCACCCGGATCGC
TCCCTGAAGACCCTTGCCGAGGATGGCCACGCCGCGCGCGGGCGTTTCGAGGCCCGCGCCGGCCGCAACAAGGGCGATGC
TTCCAACCGGCCGATTATCCGCGTGCGGCCGGGGGCGCCGGGTTGGCTGGATCAGCTCCGCTCGGCGGAGTCCATGGGCG
CGCAGATCGGAATTTTCTAG

Upstream 100 bases:

>100_bases
CACGGCGAAGGTCAGGTCGCCGCCGTCGCTGCTGCCGTTATCGAAGCTGTCGGTGCTCATGCCTCCCAACGCTAGTCGGC
TTTGTGGAACACTGGGTAGC

Downstream 100 bases:

>100_bases
CAGTCGTCCTTCGTCTTGGCCGGCGGGGCGCCTTCCAGCACGTCAGGCAGCTTCTTCGCCAGGGCATCCACGCCATCCCA
CGCAGTAGGTTCCAGCCCAT

Product: prephenate dehydrogenase

Products: 4-hydroxyphenylpyruvate; CO2; NADH

Alternate protein names: Prephenate Dehydrogenase TyrA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSYEISSDYRLSTLPEDRRPLCILGLGLIGGSLMRDAQAAGWPVFGWNRSEKTVTRARRDGYDVSADLEATLRRAEETDA
LLILGVPMPALSFLLDAISQHAPTCGFTDVTSVKQEVHDLVEAKGMSDRFVGGHPMAGTANSGWQATMHGLFRGAVWVVT
YDNARELAGAGAEAGAAASTGSSAAGGGATSGAAGAAPGADADEVSKRWLDTWVRVVGLAEEVGASVIPAIARRHDSAVG
RVSHLPHILAESLAVAGDSGGPLALSLAASSFRDGTRVAGTDPDLVRAMVENNRPAVLEALDQTIELLQGAREDIAHPDR
SLKTLAEDGHAARGRFEARAGRNKGDASNRPIIRVRPGAPGWLDQLRSAESMGAQIGIF

Sequences:

>Translated_379_residues
MSYEISSDYRLSTLPEDRRPLCILGLGLIGGSLMRDAQAAGWPVFGWNRSEKTVTRARRDGYDVSADLEATLRRAEETDA
LLILGVPMPALSFLLDAISQHAPTCGFTDVTSVKQEVHDLVEAKGMSDRFVGGHPMAGTANSGWQATMHGLFRGAVWVVT
YDNARELAGAGAEAGAAASTGSSAAGGGATSGAAGAAPGADADEVSKRWLDTWVRVVGLAEEVGASVIPAIARRHDSAVG
RVSHLPHILAESLAVAGDSGGPLALSLAASSFRDGTRVAGTDPDLVRAMVENNRPAVLEALDQTIELLQGAREDIAHPDR
SLKTLAEDGHAARGRFEARAGRNKGDASNRPIIRVRPGAPGWLDQLRSAESMGAQIGIF
>Mature_378_residues
SYEISSDYRLSTLPEDRRPLCILGLGLIGGSLMRDAQAAGWPVFGWNRSEKTVTRARRDGYDVSADLEATLRRAEETDAL
LILGVPMPALSFLLDAISQHAPTCGFTDVTSVKQEVHDLVEAKGMSDRFVGGHPMAGTANSGWQATMHGLFRGAVWVVTY
DNARELAGAGAEAGAAASTGSSAAGGGATSGAAGAAPGADADEVSKRWLDTWVRVVGLAEEVGASVIPAIARRHDSAVGR
VSHLPHILAESLAVAGDSGGPLALSLAASSFRDGTRVAGTDPDLVRAMVENNRPAVLEALDQTIELLQGAREDIAHPDRS
LKTLAEDGHAARGRFEARAGRNKGDASNRPIIRVRPGAPGWLDQLRSAESMGAQIGIF

Specific function: Unknown

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.3.1.12

Molecular weight: Translated: 39702; Mature: 39571

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYEISSDYRLSTLPEDRRPLCILGLGLIGGSLMRDAQAAGWPVFGWNRSEKTVTRARRD
CCCCCCCCCEECCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHC
GYDVSADLEATLRRAEETDALLILGVPMPALSFLLDAISQHAPTCGFTDVTSVKQEVHDL
CCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
VEAKGMSDRFVGGHPMAGTANSGWQATMHGLFRGAVWVVTYDNARELAGAGAEAGAAAST
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCHHHHHCCCCCCCCCCCC
GSSAAGGGATSGAAGAAPGADADEVSKRWLDTWVRVVGLAEEVGASVIPAIARRHDSAVG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVSHLPHILAESLAVAGDSGGPLALSLAASSFRDGTRVAGTDPDLVRAMVENNRPAVLEA
HHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
LDQTIELLQGAREDIAHPDRSLKTLAEDGHAARGRFEARAGRNKGDASNRPIIRVRPGAP
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHCCCHHHHCCCCCCCCCCCCEEEECCCCC
GWLDQLRSAESMGAQIGIF
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SYEISSDYRLSTLPEDRRPLCILGLGLIGGSLMRDAQAAGWPVFGWNRSEKTVTRARRD
CCCCCCCCEECCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHC
GYDVSADLEATLRRAEETDALLILGVPMPALSFLLDAISQHAPTCGFTDVTSVKQEVHDL
CCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
VEAKGMSDRFVGGHPMAGTANSGWQATMHGLFRGAVWVVTYDNARELAGAGAEAGAAAST
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCHHHHHCCCCCCCCCCCC
GSSAAGGGATSGAAGAAPGADADEVSKRWLDTWVRVVGLAEEVGASVIPAIARRHDSAVG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVSHLPHILAESLAVAGDSGGPLALSLAASSFRDGTRVAGTDPDLVRAMVENNRPAVLEA
HHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
LDQTIELLQGAREDIAHPDRSLKTLAEDGHAARGRFEARAGRNKGDASNRPIIRVRPGAP
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHCCCHHHHCCCCCCCCCCCCEEEECCCCC
GWLDQLRSAESMGAQIGIF
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: prephenate; NAD+

Specific reaction: prephenate + NAD+ = 4-hydroxyphenylpyruvate + CO2 + NADH

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA