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The map label for this gene is aroA [H]

Identifier: 68536712

GI number: 68536712

Start: 1903423

End: 1904712

Strand: Direct

Name: aroA [H]

Synonym: jk1625

Alternate gene names: 68536712

Gene position: 1903423-1904712 (Clockwise)

Preceding gene: 68536706

Following gene: 68536713

Centisome position: 77.3

GC content: 66.51

Gene sequence:

>1290_bases
ATGTCTGAACAACTCTGGCCGGCCCCGGTCGCCACCGAGCCCGTACAGGCCACCGTGGCGATCCCCGGCTCGAAATCCAT
CACGAACCGTGCGCTGATCCTCGCCGCGCTGGCGGATGCGCCTTCCACCATCACCGGTGGGCTGGTGAGCCGCGATACGG
AGCTGATGATGTCGGCTCTGCGTGCCTTGGGGACCCAGATCCTATTGAAGAACGACCAAATCTACGTCACCCCAGCGGAA
AAGCTGCACGGCGGTGAGGTGGATTGCGGCCTGGCTGGAACCGTAATGCGCTTCGTCCCGCCGATCGCTGCCCTGGCCAC
TGGCACGGTTGCTTTCGACGGTGACGTGGAGGCGCGCCGCCGCCCGATGTCTACCACTTTGGATTCCCTGCGTGCCCTTG
GCGCCACCGTGAAAACAAGCACCGAGTGCAACCCGGAGGGGTTGCCTTTCTTCGTGGAGGGTTCCGGGGAGATCCAGGGC
GGGGAGATCACCATCGATGCTTCCCAGTCCTCCCAGTTCGTCAGCGGCTTGCTCCTGGCCGGTGCGCGCTTCACCGAGGG
GGTTACCGTTATCCACGAGGGTAACTCCCTGCCCAGCCAGCCCCACGTCGAGATGACGGTGCAGATGTTGCGTGAGGCCG
GGGTGCACGTCGAGACCTCCTTCAACCGGTGGACCGTCCACCCCGGCCCGATCCGTGGCCGTCAATGGCACGTGGAGCCG
GACCTGTCGAACGCCACCCCGTTCATGGCCGCGGGCGTGCTCACCGGTGGCACCGTGCGCATTCAGAACTGGCCCGCCAC
CACCAACCAGCCGGGCGACCAGTTCCGCCAGATCCTGTTGGACATGGGCGCGGAGGCGGAGCTGGACGTCCATCACGGCG
ATCTTGTTGTCTCCAGCACCGGCCGCATCAACGGGATTACCTGGGACATGCACGATATTGGGGAGCTCACCCCCACCGTC
GCCGCCCTGGCGGCCCTGGCCGATGGACCTAGCCACCTCTACGGAATCGCGCACCTGCGCGGCCACGAGACCGACCGACT
ACAGGCCCTGGCGGATAACATCAACGCCCTGGGTGGCAACGTCGAGCAGACCGCCGACGGGCTGATCATCCACCCGGCTG
CCCTGGAGGGTGGCCGCTGGGAGTCCTACGCCGATCACCGCATGGCCACCGCCGGAGCGATCCTGGGCCTGCGCGTCGAA
GGCATCCACGTCTCCGACGTGGACACCACCGCCAAGACCCTTCCCGGCTTCCGCCGCCGCTGGGCGCAGCTGCTGGGCCA
GGAACGTTAA

Upstream 100 bases:

>100_bases
AGCTGAACAATACGTATCGGCCACACATACTCGCCCATTATGCCCACCCCACACTTCTTTTCCAGGCAAAAAGTGAGACA
ATGTGGGTATGTCTGCAGGT

Downstream 100 bases:

>100_bases
ATGGGGCGACGGCACAGCAACGCCCATCACTGGGACGAATCCGATGTCCGCGTCCGTCCAGGTAAGGGCTCTCGCCCGCG
GACCAAGGATCGGCCGAGCC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSEQLWPAPVATEPVQATVAIPGSKSITNRALILAALADAPSTITGGLVSRDTELMMSALRALGTQILLKNDQIYVTPAE
KLHGGEVDCGLAGTVMRFVPPIAALATGTVAFDGDVEARRRPMSTTLDSLRALGATVKTSTECNPEGLPFFVEGSGEIQG
GEITIDASQSSQFVSGLLLAGARFTEGVTVIHEGNSLPSQPHVEMTVQMLREAGVHVETSFNRWTVHPGPIRGRQWHVEP
DLSNATPFMAAGVLTGGTVRIQNWPATTNQPGDQFRQILLDMGAEAELDVHHGDLVVSSTGRINGITWDMHDIGELTPTV
AALAALADGPSHLYGIAHLRGHETDRLQALADNINALGGNVEQTADGLIIHPAALEGGRWESYADHRMATAGAILGLRVE
GIHVSDVDTTAKTLPGFRRRWAQLLGQER

Sequences:

>Translated_429_residues
MSEQLWPAPVATEPVQATVAIPGSKSITNRALILAALADAPSTITGGLVSRDTELMMSALRALGTQILLKNDQIYVTPAE
KLHGGEVDCGLAGTVMRFVPPIAALATGTVAFDGDVEARRRPMSTTLDSLRALGATVKTSTECNPEGLPFFVEGSGEIQG
GEITIDASQSSQFVSGLLLAGARFTEGVTVIHEGNSLPSQPHVEMTVQMLREAGVHVETSFNRWTVHPGPIRGRQWHVEP
DLSNATPFMAAGVLTGGTVRIQNWPATTNQPGDQFRQILLDMGAEAELDVHHGDLVVSSTGRINGITWDMHDIGELTPTV
AALAALADGPSHLYGIAHLRGHETDRLQALADNINALGGNVEQTADGLIIHPAALEGGRWESYADHRMATAGAILGLRVE
GIHVSDVDTTAKTLPGFRRRWAQLLGQER
>Mature_428_residues
SEQLWPAPVATEPVQATVAIPGSKSITNRALILAALADAPSTITGGLVSRDTELMMSALRALGTQILLKNDQIYVTPAEK
LHGGEVDCGLAGTVMRFVPPIAALATGTVAFDGDVEARRRPMSTTLDSLRALGATVKTSTECNPEGLPFFVEGSGEIQGG
EITIDASQSSQFVSGLLLAGARFTEGVTVIHEGNSLPSQPHVEMTVQMLREAGVHVETSFNRWTVHPGPIRGRQWHVEPD
LSNATPFMAAGVLTGGTVRIQNWPATTNQPGDQFRQILLDMGAEAELDVHHGDLVVSSTGRINGITWDMHDIGELTPTVA
ALAALADGPSHLYGIAHLRGHETDRLQALADNINALGGNVEQTADGLIIHPAALEGGRWESYADHRMATAGAILGLRVEG
IHVSDVDTTAKTLPGFRRRWAQLLGQER

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=436, Percent_Identity=32.3394495412844, Blast_Score=169, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6320332, Length=461, Percent_Identity=29.0672451193059, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 45598; Mature: 45467

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQLWPAPVATEPVQATVAIPGSKSITNRALILAALADAPSTITGGLVSRDTELMMSAL
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCHHCCCHHHHHHHH
RALGTQILLKNDQIYVTPAEKLHGGEVDCGLAGTVMRFVPPIAALATGTVAFDGDVEARR
HHCCCEEEEECCEEEEECHHHHCCCCCCCCHHHHHHHHHCCHHHHHCCCEEECCCHHHHC
RPMSTTLDSLRALGATVKTSTECNPEGLPFFVEGSGEIQGGEITIDASQSSQFVSGLLLA
CCHHHHHHHHHHHCCCEECCCCCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHH
GARFTEGVTVIHEGNSLPSQPHVEMTVQMLREAGVHVETSFNRWTVHPGPIRGRQWHVEP
CCHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEECCCCCCCCCEEEECC
DLSNATPFMAAGVLTGGTVRIQNWPATTNQPGDQFRQILLDMGAEAELDVHHGDLVVSST
CCCCCCCHHHHHEECCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCEEEECC
GRINGITWDMHDIGELTPTVAALAALADGPSHLYGIAHLRGHETDRLQALADNINALGGN
CCCCCEEECHHHHHHHHHHHHHHHHHCCCHHHEEEEEHHCCCCHHHHHHHHHHHHHCCCC
VEQTADGLIIHPAALEGGRWESYADHRMATAGAILGLRVEGIHVSDVDTTAKTLPGFRRR
HHHCCCCEEEEECCCCCCCCCCHHHHHHHHHCEEEEEEEECEEECCCCHHHHHCHHHHHH
WAQLLGQER
HHHHHCCCC
>Mature Secondary Structure 
SEQLWPAPVATEPVQATVAIPGSKSITNRALILAALADAPSTITGGLVSRDTELMMSAL
CCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCHHCCCHHHHHHHH
RALGTQILLKNDQIYVTPAEKLHGGEVDCGLAGTVMRFVPPIAALATGTVAFDGDVEARR
HHCCCEEEEECCEEEEECHHHHCCCCCCCCHHHHHHHHHCCHHHHHCCCEEECCCHHHHC
RPMSTTLDSLRALGATVKTSTECNPEGLPFFVEGSGEIQGGEITIDASQSSQFVSGLLLA
CCHHHHHHHHHHHCCCEECCCCCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHH
GARFTEGVTVIHEGNSLPSQPHVEMTVQMLREAGVHVETSFNRWTVHPGPIRGRQWHVEP
CCHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEECCCCCCCCCEEEECC
DLSNATPFMAAGVLTGGTVRIQNWPATTNQPGDQFRQILLDMGAEAELDVHHGDLVVSST
CCCCCCCHHHHHEECCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCEEEECC
GRINGITWDMHDIGELTPTVAALAALADGPSHLYGIAHLRGHETDRLQALADNINALGGN
CCCCCEEECHHHHHHHHHHHHHHHHHCCCHHHEEEEEHHCCCCHHHHHHHHHHHHHCCCC
VEQTADGLIIHPAALEGGRWESYADHRMATAGAILGLRVEGIHVSDVDTTAKTLPGFRRR
HHHCCCCEEEEECCCCCCCCCCHHHHHHHHHCEEEEEEEECEEECCCCHHHHHCHHHHHH
WAQLLGQER
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA