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The map label for this gene is mepA [H]

Identifier: 68536645

GI number: 68536645

Start: 1829955

End: 1830713

Strand: Direct

Name: mepA [H]

Synonym: jk1559

Alternate gene names: 68536645

Gene position: 1829955-1830713 (Clockwise)

Preceding gene: 68536626

Following gene: 68536646

Centisome position: 74.31

GC content: 65.88

Gene sequence:

>759_bases
GTGCGAAACACTACTGAAGCGAGCCGTACCGGCATCCACCGCAAGCAGGAGAACACCGCGAAGCGCCGCTTCGCGCTCGT
GGCGGTCGCTACCACCGCTGTGACTACTGCTGGCGCTGCCGGCGCTACCGCTGGTGCATCCCAGAACTCCAAGGACGATA
TCGCCCTGGCTTCCGAGAACACCACCATCCTCGCCCAGGGCGAGGGAGCTCAGGGCTCTGCAGCTCCGGCGGACGCTCAG
GCGACCGCCAACGAGGCTCCGCAGATCCTCGAGGTTCCGCAGGCTAAGCCGGTTTCCGATCTGTCTCAGCAGCTCGACTC
CGCCCTGCGCTTCGCCAAGGAGCGCACCGAGGCTGATCTGGCTGCTCGCATGCCCGAGTACGTCAAGCCCGCCGAGGGCT
CCTTCACTTCCGGCTTCGGTTCGCGTTGGGGCACCGTCCACAAGGGCATCGACATCGCCAACGCTGTGGGCACCGCCATC
CGCGCCGTACACGACGGCACCGTCATTGACTCCGGCCCGGCTTCCGGCTTCGGCAACTGGATTCGCATCAAGCACGACGA
CGGCACCATCACCGTCTACGGCCACATGGCCACCCTGGACGTTAAGGTTGGCGACCGTGTAACCGCCGGCCAGAAGATCG
CCGGCATGGGCTCCGAGGGCTTCTCCACCGGCTCCCACCTGCACTTCGAGGTTCGCCCGAACGATGGCGACGCTATCGAC
CCGAAGCCTTGGCTCGCCGAGCGCGGCATCCAGCTTTAA

Upstream 100 bases:

>100_bases
GCCCCAACAATCAGGCTCGGGGAAGAGCGAAAGCGATAGTGCGAAATCACATGTGACAGTTGTTAAAAAACATCGATTAG
GTCAAAGGGTTACTAGGACA

Downstream 100 bases:

>100_bases
GGCTTAGCTAGAACCACAAAGAAAACCTCCCGACCGCCTCCGTTGAACTGCTCCCCATTAGTTGGACTGAGAAATCAGTT
ACCGACTAGTGGGGAGCAGT

Product: putative secreted metallopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MRNTTEASRTGIHRKQENTAKRRFALVAVATTAVTTAGAAGATAGASQNSKDDIALASENTTILAQGEGAQGSAAPADAQ
ATANEAPQILEVPQAKPVSDLSQQLDSALRFAKERTEADLAARMPEYVKPAEGSFTSGFGSRWGTVHKGIDIANAVGTAI
RAVHDGTVIDSGPASGFGNWIRIKHDDGTITVYGHMATLDVKVGDRVTAGQKIAGMGSEGFSTGSHLHFEVRPNDGDAID
PKPWLAERGIQL

Sequences:

>Translated_252_residues
MRNTTEASRTGIHRKQENTAKRRFALVAVATTAVTTAGAAGATAGASQNSKDDIALASENTTILAQGEGAQGSAAPADAQ
ATANEAPQILEVPQAKPVSDLSQQLDSALRFAKERTEADLAARMPEYVKPAEGSFTSGFGSRWGTVHKGIDIANAVGTAI
RAVHDGTVIDSGPASGFGNWIRIKHDDGTITVYGHMATLDVKVGDRVTAGQKIAGMGSEGFSTGSHLHFEVRPNDGDAID
PKPWLAERGIQL
>Mature_252_residues
MRNTTEASRTGIHRKQENTAKRRFALVAVATTAVTTAGAAGATAGASQNSKDDIALASENTTILAQGEGAQGSAAPADAQ
ATANEAPQILEVPQAKPVSDLSQQLDSALRFAKERTEADLAARMPEYVKPAEGSFTSGFGSRWGTVHKGIDIANAVGTAI
RAVHDGTVIDSGPASGFGNWIRIKHDDGTITVYGHMATLDVKVGDRVTAGQKIAGMGSEGFSTGSHLHFEVRPNDGDAID
PKPWLAERGIQL

Specific function: May Be Involved In Stationary-Phase Survival. [C]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Attached To The Inner Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 10 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1789099, Length=120, Percent_Identity=45, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI87082297, Length=104, Percent_Identity=38.4615384615385, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI87082174, Length=104, Percent_Identity=44.2307692307692, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081989, Length=95, Percent_Identity=37.8947368421053, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR008258
- InterPro:   IPR016047
- InterPro:   IPR010090
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01551 Peptidase_M23; PF10145 PhageMin_Tail; PF01464 SLT [H]

EC number: NA

Molecular weight: Translated: 26258; Mature: 26258

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNTTEASRTGIHRKQENTAKRRFALVAVATTAVTTAGAAGATAGASQNSKDDIALASEN
CCCCCCHHHHCCCHHHHHHHHHHEEEEEEHHHHHHHCCCCCCCCCCCCCCCCCEEEECCC
TTILAQGEGAQGSAAPADAQATANEAPQILEVPQAKPVSDLSQQLDSALRFAKERTEADL
CEEEEECCCCCCCCCCCCCCHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AARMPEYVKPAEGSFTSGFGSRWGTVHKGIDIANAVGTAIRAVHDGTVIDSGPASGFGNW
HHHCHHHCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCE
IRIKHDDGTITVYGHMATLDVKVGDRVTAGQKIAGMGSEGFSTGSHLHFEVRPNDGDAID
EEEEECCCEEEEEEEEEEEEEECCCCCCCCCEEECCCCCCCCCCCEEEEEEECCCCCCCC
PKPWLAERGIQL
CCCHHHHCCCCC
>Mature Secondary Structure
MRNTTEASRTGIHRKQENTAKRRFALVAVATTAVTTAGAAGATAGASQNSKDDIALASEN
CCCCCCHHHHCCCHHHHHHHHHHEEEEEEHHHHHHHCCCCCCCCCCCCCCCCCEEEECCC
TTILAQGEGAQGSAAPADAQATANEAPQILEVPQAKPVSDLSQQLDSALRFAKERTEADL
CEEEEECCCCCCCCCCCCCCHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AARMPEYVKPAEGSFTSGFGSRWGTVHKGIDIANAVGTAIRAVHDGTVIDSGPASGFGNW
HHHCHHHCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCE
IRIKHDDGTITVYGHMATLDVKVGDRVTAGQKIAGMGSEGFSTGSHLHFEVRPNDGDAID
EEEEECCCEEEEEEEEEEEEEECCCCCCCCCEEECCCCCCCCCCCEEEEEEECCCCCCCC
PKPWLAERGIQL
CCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]