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The map label for this gene is dcp [H]

Identifier: 68535666

GI number: 68535666

Start: 717990

End: 720128

Strand: Direct

Name: dcp [H]

Synonym: jk0594

Alternate gene names: 68535666

Gene position: 717990-720128 (Clockwise)

Preceding gene: 68535661

Following gene: 68535667

Centisome position: 29.16

GC content: 65.59

Gene sequence:

>2139_bases
ATGGATTACCTCCAAAACGCTTCCGAACTGCCTTATGAACTGCCCGACTTCGCGGCAATCGACCTTGCCGAGCTGGTGCC
TGCCTTCCGCACCGCGCTGGTGGATCACGCCGCGCAGATCGCGGCGATCGCGAACAACCCTGAAGCTCCCACCTGGGAAA
ATACCGCCGAGGCGTGGGAAGAATCGGGGCAGATGCTGCAGCGCGTGCTGGCCATTGTTTTTAATTATACGGGCGCAAAT
GCCACCGATCAGGTGCGCGAGATTGAGGCGACGATCAGCCCAGAGTTGGCGCGGCACTTCAGCGAAATCTGGCTGAACCG
GAAGCTGTGGGAGCGCATTTGCGACCTGCCCGAGCAACCGGAAGGCAGCGAAGAGGAAGCCCTGCTGCGGGAGCTGAAGA
AGAGCTTTATTCGCGGTGGTGCCGAACTGGACGATGCGCAGCGGGAAAGCCTGCGCGACATCGACGCCCAACTGGCGGAG
CTGACCACCGCCTTCGGCGCGCAGCTGCAGACCGCCACCGAAGACGCGGCGGTGCTGCTGACAGACGAGGCCGAGGTCGC
GGGGCTGAGCGCGGCGGACAAGGAGTACTTCGCCAAGGCCGCCAACGAACGCGGGGAGGAAGGCTGGCTGATTCGCCTGG
GCCTGCCGAGCATCCAGCCGGTGCTGGAATCTCTTGAAAACCCGGCCGCGCGCGCGAAGGTGCACGAGGCATCGCTGAAC
CGCGCCGCCGGCAGCAACGAGGCCACACTGCTGCAGATCGTGCGCCTGCGCGCCCAGCGCGCCGAGCTGCTGGGCTTTGC
CAATCACGCCGAGTTCGTCGCCGCCGCCGAGACCGCCGGTAGCCTCGCGGCGGTCGAGGATCTGCTGAATCAGGTGACGC
CCGCCGCCGTGGCGAACGCGCACGGAGAGTACAAGCGGGCGCTGGACAAGATGGCCGTGAGTGGCACAGAGCCCTCAGCG
GGTACAGAGAGCGCAGCGGGTACAGCGGGGCTGAGCGGGGCCGACTGGCCCTACTGGGATGCCCAGCTGCGCGCAGAAGA
GCTGGACGTCGATGAAGCCGAGCTGAAGAAGTACTTCCCGCTGGAACAGGTTATGGTCGACGGTGCCTTCTTTGCCGCCA
AGCGCCTCTACGGCATTGACGTGCGGGAACGCACCGACCTCGCCGGCTACGCGCCGGGCGTGCGGGTATGGGAAGTCACT
GAGGGTGAAGAGTCGCCCGTCGGCATCGGCCTGCTGCTGACCGACATGTACGCCCGCCCCACCAAGCGCGGTGGCGCGTG
GATGAACTCCTTCGTCGAACAATCCAACCTGCTGGGCAAGGCCCCCGTGGTGGTCAACGTCATGAACATCGCCGAACCCG
CCGAGGGCGAGCAGGCGCTGTTGACCCTCGACGAGGTGCAGACCGTTTTCCACGAGTTCGGCCACGCCCTGCACGGCCTG
CTCTCCGACGTGCGCTATCCCACGCTGTCCGGCACAAATGTGCCCCGCGACTTCGTGGAGTTTCCCAGCCAGATCAACGA
AAACTGGGCTTTAGAGCCCGCCGTACTGCGCAACTACGCCCGCCACGTGGAAACCGGGGAAGTTATCAGTGGCGAGTTCG
TCGATGCGATCCGCGCCCAGGCGAAGTGGGGGCAGGGTCTGGCCACCACCGAGTTCTTGGCCGCCTGCTGGTTGGACCTG
GCCTGGCACAAGCTCTCCGCCGCGGAGGCGGAGCAGCTCGCCGCCACGGACGATGCCGCCGCCCAGGTGGAATCCTTCGA
GGCCGAAGCCCTGGAGCGCGCCGGGGTGGACGTCAACGGCGCGCTTGCCCCGCGCTATCGCTCGGCTTATTTCAACCACA
TCTTCGCTGGCGGCTACTCCGCCGACTACTGGAGCTACCTGTGGGCGGAGGTGCTGGACGCCGACGGTTTCCAGGCCTTC
GTCGACACTGGCGCTGCGGTCGGTGAGTCCGGTACAGATTCTAATGACGCCACCGCCGACCTCGACGACGACGATGTTCG
CTTCGCGGGCGAGCGTTTCCGCCGCATTATCCTCTCCCGCGGCGCTAGCATCGACTTCGAAGATGCATTCTGGATGTTCC
GTGGCCAGCAGCGCAGCGTGCAACCGCTACTTGACCGCCGTGGGCTCAGTCAGGGGTAG

Upstream 100 bases:

>100_bases
CTCGAAGCGGAGTACGGAACCGCGGAGGAAGCCACGTTTGCGACCCTGTTTGATGGCCACATCAACGTAGTTGTTGGCCT
CAGGGATAGAGTGGGGGATC

Downstream 100 bases:

>100_bases
ATGATGGAATGGCTTATCAACGCGCCGGTGTGGATCCAAACCCCGCTAGTGTTCCTCGCACTATTCGTGGTTTGCACCGT
GTTGGCCTTAGTATGGCAGG

Product: peptidyl-dipeptidase

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 712; Mature: 712

Protein sequence:

>712_residues
MDYLQNASELPYELPDFAAIDLAELVPAFRTALVDHAAQIAAIANNPEAPTWENTAEAWEESGQMLQRVLAIVFNYTGAN
ATDQVREIEATISPELARHFSEIWLNRKLWERICDLPEQPEGSEEEALLRELKKSFIRGGAELDDAQRESLRDIDAQLAE
LTTAFGAQLQTATEDAAVLLTDEAEVAGLSAADKEYFAKAANERGEEGWLIRLGLPSIQPVLESLENPAARAKVHEASLN
RAAGSNEATLLQIVRLRAQRAELLGFANHAEFVAAAETAGSLAAVEDLLNQVTPAAVANAHGEYKRALDKMAVSGTEPSA
GTESAAGTAGLSGADWPYWDAQLRAEELDVDEAELKKYFPLEQVMVDGAFFAAKRLYGIDVRERTDLAGYAPGVRVWEVT
EGEESPVGIGLLLTDMYARPTKRGGAWMNSFVEQSNLLGKAPVVVNVMNIAEPAEGEQALLTLDEVQTVFHEFGHALHGL
LSDVRYPTLSGTNVPRDFVEFPSQINENWALEPAVLRNYARHVETGEVISGEFVDAIRAQAKWGQGLATTEFLAACWLDL
AWHKLSAAEAEQLAATDDAAAQVESFEAEALERAGVDVNGALAPRYRSAYFNHIFAGGYSADYWSYLWAEVLDADGFQAF
VDTGAAVGESGTDSNDATADLDDDDVRFAGERFRRIILSRGASIDFEDAFWMFRGQQRSVQPLLDRRGLSQG

Sequences:

>Translated_712_residues
MDYLQNASELPYELPDFAAIDLAELVPAFRTALVDHAAQIAAIANNPEAPTWENTAEAWEESGQMLQRVLAIVFNYTGAN
ATDQVREIEATISPELARHFSEIWLNRKLWERICDLPEQPEGSEEEALLRELKKSFIRGGAELDDAQRESLRDIDAQLAE
LTTAFGAQLQTATEDAAVLLTDEAEVAGLSAADKEYFAKAANERGEEGWLIRLGLPSIQPVLESLENPAARAKVHEASLN
RAAGSNEATLLQIVRLRAQRAELLGFANHAEFVAAAETAGSLAAVEDLLNQVTPAAVANAHGEYKRALDKMAVSGTEPSA
GTESAAGTAGLSGADWPYWDAQLRAEELDVDEAELKKYFPLEQVMVDGAFFAAKRLYGIDVRERTDLAGYAPGVRVWEVT
EGEESPVGIGLLLTDMYARPTKRGGAWMNSFVEQSNLLGKAPVVVNVMNIAEPAEGEQALLTLDEVQTVFHEFGHALHGL
LSDVRYPTLSGTNVPRDFVEFPSQINENWALEPAVLRNYARHVETGEVISGEFVDAIRAQAKWGQGLATTEFLAACWLDL
AWHKLSAAEAEQLAATDDAAAQVESFEAEALERAGVDVNGALAPRYRSAYFNHIFAGGYSADYWSYLWAEVLDADGFQAF
VDTGAAVGESGTDSNDATADLDDDDVRFAGERFRRIILSRGASIDFEDAFWMFRGQQRSVQPLLDRRGLSQG
>Mature_712_residues
MDYLQNASELPYELPDFAAIDLAELVPAFRTALVDHAAQIAAIANNPEAPTWENTAEAWEESGQMLQRVLAIVFNYTGAN
ATDQVREIEATISPELARHFSEIWLNRKLWERICDLPEQPEGSEEEALLRELKKSFIRGGAELDDAQRESLRDIDAQLAE
LTTAFGAQLQTATEDAAVLLTDEAEVAGLSAADKEYFAKAANERGEEGWLIRLGLPSIQPVLESLENPAARAKVHEASLN
RAAGSNEATLLQIVRLRAQRAELLGFANHAEFVAAAETAGSLAAVEDLLNQVTPAAVANAHGEYKRALDKMAVSGTEPSA
GTESAAGTAGLSGADWPYWDAQLRAEELDVDEAELKKYFPLEQVMVDGAFFAAKRLYGIDVRERTDLAGYAPGVRVWEVT
EGEESPVGIGLLLTDMYARPTKRGGAWMNSFVEQSNLLGKAPVVVNVMNIAEPAEGEQALLTLDEVQTVFHEFGHALHGL
LSDVRYPTLSGTNVPRDFVEFPSQINENWALEPAVLRNYARHVETGEVISGEFVDAIRAQAKWGQGLATTEFLAACWLDL
AWHKLSAAEAEQLAATDDAAAQVESFEAEALERAGVDVNGALAPRYRSAYFNHIFAGGYSADYWSYLWAEVLDADGFQAF
VDTGAAVGESGTDSNDATADLDDDDVRFAGERFRRIILSRGASIDFEDAFWMFRGQQRSVQPLLDRRGLSQG

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=623, Percent_Identity=28.892455858748, Blast_Score=183, Evalue=6e-46,
Organism=Homo sapiens, GI14149738, Length=679, Percent_Identity=26.6568483063328, Blast_Score=179, Evalue=9e-45,
Organism=Homo sapiens, GI156105687, Length=366, Percent_Identity=25.6830601092896, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI1787819, Length=712, Percent_Identity=38.4831460674157, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1789913, Length=726, Percent_Identity=30.1652892561983, Blast_Score=268, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI32565901, Length=555, Percent_Identity=21.981981981982, Blast_Score=74, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319793, Length=635, Percent_Identity=23.3070866141732, Blast_Score=148, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6322715, Length=452, Percent_Identity=23.4513274336283, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21356111, Length=578, Percent_Identity=22.6643598615917, Blast_Score=128, Evalue=2e-29,
Organism=Drosophila melanogaster, GI20129717, Length=362, Percent_Identity=27.6243093922652, Blast_Score=97, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 77732; Mature: 77732

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYLQNASELPYELPDFAAIDLAELVPAFRTALVDHAAQIAAIANNPEAPTWENTAEAWE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
ESGQMLQRVLAIVFNYTGANATDQVREIEATISPELARHFSEIWLNRKLWERICDLPEQP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHCCCCCC
EGSEEEALLRELKKSFIRGGAELDDAQRESLRDIDAQLAELTTAFGAQLQTATEDAAVLL
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TDEAEVAGLSAADKEYFAKAANERGEEGWLIRLGLPSIQPVLESLENPAARAKVHEASLN
ECCHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHH
RAAGSNEATLLQIVRLRAQRAELLGFANHAEFVAAAETAGSLAAVEDLLNQVTPAAVANA
HCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHC
HGEYKRALDKMAVSGTEPSAGTESAAGTAGLSGADWPYWDAQLRAEELDVDEAELKKYFP
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHCC
LEQVMVDGAFFAAKRLYGIDVRERTDLAGYAPGVRVWEVTEGEESPVGIGLLLTDMYARP
HHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCC
TKRGGAWMNSFVEQSNLLGKAPVVVNVMNIAEPAEGEQALLTLDEVQTVFHEFGHALHGL
CCCCHHHHHHHHHHHHCCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSDVRYPTLSGTNVPRDFVEFPSQINENWALEPAVLRNYARHVETGEVISGEFVDAIRAQ
HHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHH
AKWGQGLATTEFLAACWLDLAWHKLSAAEAEQLAATDDAAAQVESFEAEALERAGVDVNG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
ALAPRYRSAYFNHIFAGGYSADYWSYLWAEVLDADGFQAFVDTGAAVGESGTDSNDATAD
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHCCHHCCCCCCCCCCCCCC
LDDDDVRFAGERFRRIILSRGASIDFEDAFWMFRGQQRSVQPLLDRRGLSQG
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCC
>Mature Secondary Structure
MDYLQNASELPYELPDFAAIDLAELVPAFRTALVDHAAQIAAIANNPEAPTWENTAEAWE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
ESGQMLQRVLAIVFNYTGANATDQVREIEATISPELARHFSEIWLNRKLWERICDLPEQP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHCCCCCC
EGSEEEALLRELKKSFIRGGAELDDAQRESLRDIDAQLAELTTAFGAQLQTATEDAAVLL
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TDEAEVAGLSAADKEYFAKAANERGEEGWLIRLGLPSIQPVLESLENPAARAKVHEASLN
ECCHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHH
RAAGSNEATLLQIVRLRAQRAELLGFANHAEFVAAAETAGSLAAVEDLLNQVTPAAVANA
HCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHC
HGEYKRALDKMAVSGTEPSAGTESAAGTAGLSGADWPYWDAQLRAEELDVDEAELKKYFP
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHCC
LEQVMVDGAFFAAKRLYGIDVRERTDLAGYAPGVRVWEVTEGEESPVGIGLLLTDMYARP
HHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCC
TKRGGAWMNSFVEQSNLLGKAPVVVNVMNIAEPAEGEQALLTLDEVQTVFHEFGHALHGL
CCCCHHHHHHHHHHHHCCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSDVRYPTLSGTNVPRDFVEFPSQINENWALEPAVLRNYARHVETGEVISGEFVDAIRAQ
HHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHH
AKWGQGLATTEFLAACWLDLAWHKLSAAEAEQLAATDDAAAQVESFEAEALERAGVDVNG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
ALAPRYRSAYFNHIFAGGYSADYWSYLWAEVLDADGFQAFVDTGAAVGESGTDSNDATAD
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHCCHHCCCCCCCCCCCCCC
LDDDDVRFAGERFRRIILSRGASIDFEDAFWMFRGQQRSVQPLLDRRGLSQG
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]