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The map label for this gene is ectP [H]

Identifier: 68535659

GI number: 68535659

Start: 708624

End: 710495

Strand: Direct

Name: ectP [H]

Synonym: jk0587

Alternate gene names: 68535659

Gene position: 708624-710495 (Clockwise)

Preceding gene: 68535658

Following gene: 68535660

Centisome position: 28.78

GC content: 59.03

Gene sequence:

>1872_bases
ATGGAAGGCGAAAAATCTACAGCCGCGGCAAACGCGGAAAAAGTAAAGGTTGATCCACTAATCTTCTGGGTTGCCTTCGG
CTTCATCGTCGCCTTTGTTGGCTACGCGATCATCTTCAAAGACAGGGCCGCAGAAAGCCTGCAGACCGGCGCTAACTGGC
TGCTGGAGAACTTCAACTGGCTGTACATCGGCAGCATCTCCCTGGCCTTCCTTTTTCTGATGGTTCTCTTCGCCTCCCGC
TTCGGCCGCATGCGCCTGGGCGTTGAAGGCGAGCAGCCGGCATTCCGAACCTTGTCCTGGTTCGCGATGCTCTTCGCCGG
CGGCCTGGGCTCCGTGTTGATGTTCTACGGTGTGGCCGAGCCGATGAACCACGTCGTCAACGTACCTATGCAAGATGCGG
AACCGATGAGCCCCGAGGCCATCGGCGAAGCCATGGGATTCACCTTGTATCACTTCGGCCTGCACATGTGGGTCATCTTC
GCGCTGCCTGGCCTGGCTCTGGGCTACTTCATCTACAAGCGCCACCTGCCGCCGCGCGTATCAAGTATCTTCGCACCCAT
CCTCGGCGCCCGGATCTATTCGTGGCCCGGAAAGCTTATTGACGCCCTGTCTATCATCGGCACCGTTTTCGGCATCGCGG
TTTCGGTCGGGCTCGGTACGCTGCAGATCAACTCTGGCCTAGCCAAGGTGTTCGGTGCGGACACCGTCGCGTGGGTGCAG
ATCAGCATCCTTGTCGTCATCGTGGTGGCGTCGTCCATCTCGGTTTCCACGGGGCTGTCGAAGGGCATCAAGTGGCTGTC
CAACATCAACATTCTCGCGGCAACTCTGCTGATGGTGTTCGTACTGCTGACCGGCCCTACACTGCTTTTGCTGCGCGGCA
CGATGGATGCCACCAGTCTGTACGCGGAGTATCTGCCGAAGATCATGTTCTGGTCTGATTCGCAGCAGGTGAACCCGGGC
TGGCAGGGTAAGTGGACGGTCTTCTACTGGGCGTGGACGATCTGTTGGTCGCCTTTCGTGGGCATGTTCGTCGCCCGCAT
TTCCCGTGGCCGTACCGTCCGCGAGTTCATCGGCGGCGTGCTGTTGCTGCCGACCGCATTCACTATTGTTTGGTTCTCTG
TCTTTGGATACGCCGGCCTGGATATCGAAAAGAAGGAGCCGGGCGTGCTGACCAAGCCGATCGTGGAGGACGGCGATCCC
GCTACTGCGCTGTTCACCTTCTTGGAGCATTTCCCGTGGACTCTAGCCATTAGCATCCTGGCGCTGTTCGTTATCGCCAT
CTTCTTCGTCACCTCCATCGACTCCGCTGCGCTGATCAACGACATGTTCGCCGCCGGTGAGGAGGGCAAGACTCCGCTGA
TGTACCGCTTGCTGTGGTGCATCATGATCGGCGCCGTCGCAGGTGCCATCCTGATCATGGCTCCGGATTCCGGCATCGAC
GCACTGCAACAAACTGTGATCATCATTGGTTTCCCGTTCGTGCTGTTCAATTTCGTCATGATGTTCTCCCTGGTGAAGGG
AATGAATGATGACTCGGCTGCACGCCCTGAGCCGCCGAGCCGCCAGTGGGGCAAGACCGACTCTGCGGAGAAGCTGGCCG
AGCACGAAGCTCGCCCGGCCCCTGGCTATGACAACGAGGGTAACGAGCACGCCCGCTTCGAGTACGACGCGGAAGGAAAC
CTCGTCATCCCTGGCAACGTGCGCATCGAGGGAGACCTGGGGATCGTCGGTGACGTGGACAATGACGCCGAAGTTGCCCC
CGCGCGCCCGATGTATGACCAAGAGGGCGAACTGATTACCGATGAGAAGGATACGGAAGAGAAGACTGAGGACGAAAGCC
CGGCGGAAGATGAGGGCGTCAACAAGAGTTAG

Upstream 100 bases:

>100_bases
CAAACAATCTGGACGTGAAGGTCATGATTGTCCGGGAGAAAGGATAGGGTATTGCAAGACCTACGCACGTTCGAGCATGA
AACTGGGGAGTGATCCCGAC

Downstream 100 bases:

>100_bases
TTAATGCAGTCCAGAAAAAACATTGGCCACAATCGCACCTACAACATCGGTAGGCTGGATCTAGTACGAATAAACCTATA
AAAAAGGAGTGACCATGGTT

Product: hypothetical protein

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MEGEKSTAAANAEKVKVDPLIFWVAFGFIVAFVGYAIIFKDRAAESLQTGANWLLENFNWLYIGSISLAFLFLMVLFASR
FGRMRLGVEGEQPAFRTLSWFAMLFAGGLGSVLMFYGVAEPMNHVVNVPMQDAEPMSPEAIGEAMGFTLYHFGLHMWVIF
ALPGLALGYFIYKRHLPPRVSSIFAPILGARIYSWPGKLIDALSIIGTVFGIAVSVGLGTLQINSGLAKVFGADTVAWVQ
ISILVVIVVASSISVSTGLSKGIKWLSNINILAATLLMVFVLLTGPTLLLLRGTMDATSLYAEYLPKIMFWSDSQQVNPG
WQGKWTVFYWAWTICWSPFVGMFVARISRGRTVREFIGGVLLLPTAFTIVWFSVFGYAGLDIEKKEPGVLTKPIVEDGDP
ATALFTFLEHFPWTLAISILALFVIAIFFVTSIDSAALINDMFAAGEEGKTPLMYRLLWCIMIGAVAGAILIMAPDSGID
ALQQTVIIIGFPFVLFNFVMMFSLVKGMNDDSAARPEPPSRQWGKTDSAEKLAEHEARPAPGYDNEGNEHARFEYDAEGN
LVIPGNVRIEGDLGIVGDVDNDAEVAPARPMYDQEGELITDEKDTEEKTEDESPAEDEGVNKS

Sequences:

>Translated_623_residues
MEGEKSTAAANAEKVKVDPLIFWVAFGFIVAFVGYAIIFKDRAAESLQTGANWLLENFNWLYIGSISLAFLFLMVLFASR
FGRMRLGVEGEQPAFRTLSWFAMLFAGGLGSVLMFYGVAEPMNHVVNVPMQDAEPMSPEAIGEAMGFTLYHFGLHMWVIF
ALPGLALGYFIYKRHLPPRVSSIFAPILGARIYSWPGKLIDALSIIGTVFGIAVSVGLGTLQINSGLAKVFGADTVAWVQ
ISILVVIVVASSISVSTGLSKGIKWLSNINILAATLLMVFVLLTGPTLLLLRGTMDATSLYAEYLPKIMFWSDSQQVNPG
WQGKWTVFYWAWTICWSPFVGMFVARISRGRTVREFIGGVLLLPTAFTIVWFSVFGYAGLDIEKKEPGVLTKPIVEDGDP
ATALFTFLEHFPWTLAISILALFVIAIFFVTSIDSAALINDMFAAGEEGKTPLMYRLLWCIMIGAVAGAILIMAPDSGID
ALQQTVIIIGFPFVLFNFVMMFSLVKGMNDDSAARPEPPSRQWGKTDSAEKLAEHEARPAPGYDNEGNEHARFEYDAEGN
LVIPGNVRIEGDLGIVGDVDNDAEVAPARPMYDQEGELITDEKDTEEKTEDESPAEDEGVNKS
>Mature_623_residues
MEGEKSTAAANAEKVKVDPLIFWVAFGFIVAFVGYAIIFKDRAAESLQTGANWLLENFNWLYIGSISLAFLFLMVLFASR
FGRMRLGVEGEQPAFRTLSWFAMLFAGGLGSVLMFYGVAEPMNHVVNVPMQDAEPMSPEAIGEAMGFTLYHFGLHMWVIF
ALPGLALGYFIYKRHLPPRVSSIFAPILGARIYSWPGKLIDALSIIGTVFGIAVSVGLGTLQINSGLAKVFGADTVAWVQ
ISILVVIVVASSISVSTGLSKGIKWLSNINILAATLLMVFVLLTGPTLLLLRGTMDATSLYAEYLPKIMFWSDSQQVNPG
WQGKWTVFYWAWTICWSPFVGMFVARISRGRTVREFIGGVLLLPTAFTIVWFSVFGYAGLDIEKKEPGVLTKPIVEDGDP
ATALFTFLEHFPWTLAISILALFVIAIFFVTSIDSAALINDMFAAGEEGKTPLMYRLLWCIMIGAVAGAILIMAPDSGID
ALQQTVIIIGFPFVLFNFVMMFSLVKGMNDDSAARPEPPSRQWGKTDSAEKLAEHEARPAPGYDNEGNEHARFEYDAEGN
LVIPGNVRIEGDLGIVGDVDNDAEVAPARPMYDQEGELITDEKDTEEKTEDESPAEDEGVNKS

Specific function: High-affinity uptake of glycine betaine [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=523, Percent_Identity=35.755258126195, Blast_Score=314, Evalue=1e-86,
Organism=Escherichia coli, GI1788102, Length=479, Percent_Identity=27.9749478079332, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI1786224, Length=438, Percent_Identity=26.4840182648402, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 68301; Mature: 68301

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGEKSTAAANAEKVKVDPLIFWVAFGFIVAFVGYAIIFKDRAAESLQTGANWLLENFNW
CCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
LYIGSISLAFLFLMVLFASRFGRMRLGVEGEQPAFRTLSWFAMLFAGGLGSVLMFYGVAE
EEEHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
PMNHVVNVPMQDAEPMSPEAIGEAMGFTLYHFGLHMWVIFALPGLALGYFIYKRHLPPRV
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SSIFAPILGARIYSWPGKLIDALSIIGTVFGIAVSVGLGTLQINSGLAKVFGADTVAWVQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHCCCHHHHHH
ISILVVIVVASSISVSTGLSKGIKWLSNINILAATLLMVFVLLTGPTLLLLRGTMDATSL
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHH
YAEYLPKIMFWSDSQQVNPGWQGKWTVFYWAWTICWSPFVGMFVARISRGRTVREFIGGV
HHHHHHHHEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCH
LLLPTAFTIVWFSVFGYAGLDIEKKEPGVLTKPIVEDGDPATALFTFLEHFPWTLAISIL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHH
ALFVIAIFFVTSIDSAALINDMFAAGEEGKTPLMYRLLWCIMIGAVAGAILIMAPDSGID
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCCCHH
ALQQTVIIIGFPFVLFNFVMMFSLVKGMNDDSAARPEPPSRQWGKTDSAEKLAEHEARPA
HHHHHHHHEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
PGYDNEGNEHARFEYDAEGNLVIPGNVRIEGDLGIVGDVDNDAEVAPARPMYDQEGELIT
CCCCCCCCCCCEEEECCCCCEEECCCEEEECCCEEEECCCCCCCCCCCCCCCCCCCCEEC
DEKDTEEKTEDESPAEDEGVNKS
CCCCCHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEGEKSTAAANAEKVKVDPLIFWVAFGFIVAFVGYAIIFKDRAAESLQTGANWLLENFNW
CCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
LYIGSISLAFLFLMVLFASRFGRMRLGVEGEQPAFRTLSWFAMLFAGGLGSVLMFYGVAE
EEEHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
PMNHVVNVPMQDAEPMSPEAIGEAMGFTLYHFGLHMWVIFALPGLALGYFIYKRHLPPRV
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SSIFAPILGARIYSWPGKLIDALSIIGTVFGIAVSVGLGTLQINSGLAKVFGADTVAWVQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHCCCHHHHHH
ISILVVIVVASSISVSTGLSKGIKWLSNINILAATLLMVFVLLTGPTLLLLRGTMDATSL
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHH
YAEYLPKIMFWSDSQQVNPGWQGKWTVFYWAWTICWSPFVGMFVARISRGRTVREFIGGV
HHHHHHHHEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCH
LLLPTAFTIVWFSVFGYAGLDIEKKEPGVLTKPIVEDGDPATALFTFLEHFPWTLAISIL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHH
ALFVIAIFFVTSIDSAALINDMFAAGEEGKTPLMYRLLWCIMIGAVAGAILIMAPDSGID
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCCCHH
ALQQTVIIIGFPFVLFNFVMMFSLVKGMNDDSAARPEPPSRQWGKTDSAEKLAEHEARPA
HHHHHHHHEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
PGYDNEGNEHARFEYDAEGNLVIPGNVRIEGDLGIVGDVDNDAEVAPARPMYDQEGELIT
CCCCCCCCCCCEEEECCCCCEEECCCEEEECCCEEEECCCCCCCCCCCCCCCCCCCCEEC
DEKDTEEKTEDESPAEDEGVNKS
CCCCCHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8752321; 9387221; 9384377 [H]