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The map label for this gene is sigW [H]

Identifier: 68535556

GI number: 68535556

Start: 593087

End: 593662

Strand: Direct

Name: sigW [H]

Synonym: jk0486

Alternate gene names: 68535556

Gene position: 593087-593662 (Clockwise)

Preceding gene: 68535555

Following gene: 68535560

Centisome position: 24.08

GC content: 61.11

Gene sequence:

>576_bases
GTGTCTAACGGATCTAACACCCCACGGAAAGAACTCACCCGCGAAGAAGAGCGCGACCTGCTGGCCAAAGCCCATAAGGG
CGACCAGCAGGCTTTCGCGCGTCTAGCGCGCCAGGCATGGGGCCGGATGTTCTCGGTCTGCCTCTCCATCACGGGCAACC
GTGCTGACGCGGAGGATGCGCTGCAGAATGCTTTGACCTCCGCGTGGAAGAACATTGAGAAGTTCGATGGGCGCGCCCGG
TTCTCCACCTGGGCCTACCGTATTGCTTCCAATGCGGCGCTGCAGATCGTGCGCTCCCGCCGGGAAGTACCGGAAGAGGA
CGCGGGTGTGGACGAGATTGCACAAACCCCGGAAGTTGGCTCGCAGGTCACCTCGGCAATGGTCGTGCGTCAGGCGCTAG
CGCAGCTGCCGGATGATTTCCGTGAAGTCATCGTCCTGCGAGAATACACGGGCATGAGTTACCAGGACATCGCCGCCCAC
CAGGGGATTCCCATTCAAACGGTGAAGTCCCGCATCAATCGCGCGCGTGCGAAGCTGAAGGCAGCACTGGTGGAAGCTGG
CGTCACAAGTGCATAA

Upstream 100 bases:

>100_bases
GATGTCGCGGACTACGGCGAGGATGATTATGGTCACGACTACGGCGATGATCACCCAGATGATCTGACTGACCTCAGCGG
AATGTAAGGGGGAGTCAGAA

Downstream 100 bases:

>100_bases
AGAATAAGACCCAGCCCCACAGGGAAGAGTCCCACAGCAAAGAGCCCCACACCATCGAGCAGTTCGTTCTCCGCTCGGTG
GGTGGGGCTCTAACTTGTGT

Product: ECF family RNA polymerase sigma factor W

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MSNGSNTPRKELTREEERDLLAKAHKGDQQAFARLARQAWGRMFSVCLSITGNRADAEDALQNALTSAWKNIEKFDGRAR
FSTWAYRIASNAALQIVRSRREVPEEDAGVDEIAQTPEVGSQVTSAMVVRQALAQLPDDFREVIVLREYTGMSYQDIAAH
QGIPIQTVKSRINRARAKLKAALVEAGVTSA

Sequences:

>Translated_191_residues
MSNGSNTPRKELTREEERDLLAKAHKGDQQAFARLARQAWGRMFSVCLSITGNRADAEDALQNALTSAWKNIEKFDGRAR
FSTWAYRIASNAALQIVRSRREVPEEDAGVDEIAQTPEVGSQVTSAMVVRQALAQLPDDFREVIVLREYTGMSYQDIAAH
QGIPIQTVKSRINRARAKLKAALVEAGVTSA
>Mature_190_residues
SNGSNTPRKELTREEERDLLAKAHKGDQQAFARLARQAWGRMFSVCLSITGNRADAEDALQNALTSAWKNIEKFDGRARF
STWAYRIASNAALQIVRSRREVPEEDAGVDEIAQTPEVGSQVTSAMVVRQALAQLPDDFREVIVLREYTGMSYQDIAAHQ
GIPIQTVKSRINRARAKLKAALVEAGVTSA

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=172, Percent_Identity=34.3023255813954, Blast_Score=83, Evalue=9e-18,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21144; Mature: 21013

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNGSNTPRKELTREEERDLLAKAHKGDQQAFARLARQAWGRMFSVCLSITGNRADAEDA
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LQNALTSAWKNIEKFDGRARFSTWAYRIASNAALQIVRSRREVPEEDAGVDEIAQTPEVG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHH
SQVTSAMVVRQALAQLPDDFREVIVLREYTGMSYQDIAAHQGIPIQTVKSRINRARAKLK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
AALVEAGVTSA
HHHHHHCCCCC
>Mature Secondary Structure 
SNGSNTPRKELTREEERDLLAKAHKGDQQAFARLARQAWGRMFSVCLSITGNRADAEDA
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LQNALTSAWKNIEKFDGRARFSTWAYRIASNAALQIVRSRREVPEEDAGVDEIAQTPEVG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHH
SQVTSAMVVRQALAQLPDDFREVIVLREYTGMSYQDIAAHQGIPIQTVKSRINRARAKLK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
AALVEAGVTSA
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]